메뉴 건너뛰기




Volumn 64, Issue 11, 2004, Pages 3966-3973

Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIC GMP PHOSPHODIESTERASE; CYCLIN D1; PROTEIN P21; SULINDAC SULFONE;

EID: 2542619027     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-3740     Document Type: Article
Times cited : (103)

References (67)
  • 1
    • 0032601592 scopus 로고    scopus 로고
    • Signal transduction by cGMP-dependent protein kinases and their emerging roles in the regulation of cell adhesion and gene expression
    • Eigenthaler M, Lohmann SM, Walter U, Pilz RB. Signal transduction by cGMP-dependent protein kinases and their emerging roles in the regulation of cell adhesion and gene expression. Rev Physiol Biochem Pharmacol 1999;135:173-209.
    • (1999) Rev Physiol Biochem Pharmacol , vol.135 , pp. 173-209
    • Eigenthaler, M.1    Lohmann, S.M.2    Walter, U.3    Pilz, R.B.4
  • 2
    • 0029964536 scopus 로고    scopus 로고
    • Signalling by cGMP-dependent protein kinases
    • Vaandrager AB, de Jonge HR. Signalling by cGMP-dependent protein kinases. Mol Cell Biochem 1996;157:23-30,
    • (1996) Mol Cell Biochem , vol.157 , pp. 23-30
    • Vaandrager, A.B.1    De Jonge, H.R.2
  • 3
    • 0033602017 scopus 로고    scopus 로고
    • Nitric oxide induces apoptotic death of cardiomyocytes via a cyclic-GMP-dependent pathway
    • Shimojo T, Hiroe M, Ishiyama S, Ito H, Nishikawa T, Marumo F. Nitric oxide induces apoptotic death of cardiomyocytes via a cyclic-GMP-dependent pathway. Exp Cell Res 1999;247:38-47.
    • (1999) Exp Cell Res , vol.247 , pp. 38-47
    • Shimojo, T.1    Hiroe, M.2    Ishiyama, S.3    Ito, H.4    Nishikawa, T.5    Marumo, F.6
  • 4
    • 0031033910 scopus 로고    scopus 로고
    • Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15
    • Loweth AC, Williams GT, Scarpello JH, Morgan NG. Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15. FEBS Lett 1997;400:285-8.
    • (1997) FEBS Lett , vol.400 , pp. 285-288
    • Loweth, A.C.1    Williams, G.T.2    Scarpello, J.H.3    Morgan, N.G.4
  • 5
    • 0032545516 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP
    • Chiche JD, Schlutsmeyer SM, Bloch DB, et al. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J Biol Chem 1998;273:34263-71.
    • (1998) J Biol Chem , vol.273 , pp. 34263-34271
    • Chiche, J.D.1    Schlutsmeyer, S.M.2    Bloch, D.B.3
  • 6
    • 0032543366 scopus 로고    scopus 로고
    • Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5)
    • Stacey P, Rulten S, Dapling A, Phillips SC. Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5). Biochem Biophys Res Commun 1998;247:249-54.
    • (1998) Biochem Biophys Res Commun , vol.247 , pp. 249-254
    • Stacey, P.1    Rulten, S.2    Dapling, A.3    Phillips, S.C.4
  • 7
    • 0031842130 scopus 로고    scopus 로고
    • Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects
    • Smolenski A, Burkhardt AM, Eigenthaler M, et al. Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects. Naunyn-Schmiedebergs Arch Pharmacol 1998;358:134-9.
    • (1998) Naunyn-Schmiedebergs Arch Pharmacol , vol.358 , pp. 134-139
    • Smolenski, A.1    Burkhardt, A.M.2    Eigenthaler, M.3
  • 8
    • 0027404913 scopus 로고
    • Intracellular cyclic GMP receptor proteins
    • Lincoln TM, Cornwell TL. Intracellular cyclic GMP receptor proteins. FASEB J 1993;7:328-38.
    • (1993) FASEB J , vol.7 , pp. 328-338
    • Lincoln, T.M.1    Cornwell, T.L.2
  • 9
    • 0032989849 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinases: Understanding in vivo functions by gene targeting
    • Ruth P. Cyclic GMP-dependent protein kinases: understanding in vivo functions by gene targeting. Pharmacol Ther 1999;82:355-72.
    • (1999) Pharmacol Ther , vol.82 , pp. 355-372
    • Ruth, P.1
  • 12
    • 0028928892 scopus 로고
    • cGMP and nitric oxide modulate thrombin-induced endothelial permeability: Regulation via different pathways in human aortic and umbilical vein endothelial cells
    • Draijer R, Atsma DE, vander Laarse A, van Hinsbergh VW. cGMP and nitric oxide modulate thrombin-induced endothelial permeability: regulation via different pathways in human aortic and umbilical vein endothelial cells. Circ Res 1995;76:199-208.
    • (1995) Circ Res , vol.76 , pp. 199-208
    • Draijer, R.1    Atsma, D.E.2    Vander Laarse, A.3    Van Hinsbergh, V.W.4
  • 13
    • 0028869124 scopus 로고
    • Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin
    • Draijer R, Vaandrager AB, Nolte C, de Jonge HR, Walter U, van Hinsbergh VW. Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin. Circ Res 1995;77:897-905,
    • (1995) Circ Res , vol.77 , pp. 897-905
    • Draijer, R.1    Vaandrager, A.B.2    Nolte, C.3    De Jonge, H.R.4    Walter, U.5    Van Hinsbergh, V.W.6
  • 14
    • 0032101741 scopus 로고    scopus 로고
    • Defective smooth muscle regulation in cGMP kinase I-deficient mice
    • Pfeifer A, Klatt P, Massberg S, et al. Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J 1998;17:3045-51.
    • (1998) EMBO J , vol.17 , pp. 3045-3051
    • Pfeifer, A.1    Klatt, P.2    Massberg, S.3
  • 15
    • 0033583481 scopus 로고    scopus 로고
    • Increased adhesion and aggregation of platelets lacking cyclic guanosine 3′,5′-monophosphate kinase I
    • Massberg S, Sausbier M, Klatt P, et al. Increased adhesion and aggregation of platelets lacking cyclic guanosine 3′,5′ -monophosphate kinase I. J Exp Med 1999; 189:1255-64.
    • (1999) J Exp Med , vol.189 , pp. 1255-1264
    • Massberg, S.1    Sausbier, M.2    Klatt, P.3
  • 16
    • 0034682801 scopus 로고    scopus 로고
    • Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I
    • Smolenski A, Poller W, Walter U, Lohmann SM. Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase I. J Biol Chem 2000;275:25723-32.
    • (2000) J Biol Chem , vol.275 , pp. 25723-25732
    • Smolenski, A.1    Poller, W.2    Walter, U.3    Lohmann, S.M.4
  • 17
    • 0027519350 scopus 로고
    • Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain
    • Uhler MD. Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain. J Biol Chem 1993;268:13586-91.
    • (1993) J Biol Chem , vol.268 , pp. 13586-13591
    • Uhler, M.D.1
  • 18
    • 0027965908 scopus 로고
    • Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II
    • Jarchau T, Hausler C, Markert T, et al. Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II. Proc Natl Acad Sci USA 1994; 91:9426-30.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9426-9430
    • Jarchau, T.1    Hausler, C.2    Markert, T.3
  • 19
    • 0032543366 scopus 로고    scopus 로고
    • Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5)
    • Stacey P, Rulten S, Dapling A, Phillips SC. Molecular cloning and expression of human cGMP-binding cGMP-specific phosphodiesterase (PDE5). Biochem Biophys Res Commun 1998;247:249-54.
    • (1998) Biochem Biophys Res Commun , vol.247 , pp. 249-254
    • Stacey, P.1    Rulten, S.2    Dapling, A.3    Phillips, S.C.4
  • 20
    • 0017229843 scopus 로고
    • Cyclic nucleotide phosphodiesterases in neoplastic and nonneoplastic human mammary tissues
    • Singer AL, Sherwin RP, Dunn AS, Appleman MM. Cyclic nucleotide phosphodiesterases in neoplastic and nonneoplastic human mammary tissues. Cancer Res 1976; 36:60-6.
    • (1976) Cancer Res , vol.36 , pp. 60-66
    • Singer, A.L.1    Sherwin, R.P.2    Dunn, A.S.3    Appleman, M.M.4
  • 21
    • 0021296011 scopus 로고
    • Cyclic nucleotide phosphodiesterase in normal and leukemic human lymphocytes and lymphoblasts
    • Epstein PM, Hachisu R. Cyclic nucleotide phosphodiesterase in normal and leukemic human lymphocytes and lymphoblasts. Adv Cyclic Nucleotide Protein Phosphorylation Res 1984;16:303-24.
    • (1984) Adv Cyclic Nucleotide Protein Phosphorylation Res , vol.16 , pp. 303-324
    • Epstein, P.M.1    Hachisu, R.2
  • 22
    • 0142026063 scopus 로고    scopus 로고
    • Phase I and II study of exisulind in combination with capecitabine in patients with metastatic breast cancer
    • Pusztai L, Zhen JH, Arun B, et al, Phase I and II study of exisulind in combination with capecitabine in patients with metastatic breast cancer. J Clin Oncol 2003;21: 3454-61.
    • (2003) J Clin Oncol , vol.21 , pp. 3454-3461
    • Pusztai, L.1    Zhen, J.H.2    Arun, B.3
  • 23
    • 0004425399 scopus 로고    scopus 로고
    • Overexpression of cGMP phosphodiesterase in colonic neoplasias compared to normal mucosa
    • Piazza GA, Xu S, Klein-Szanto A, et al. Overexpression of cGMP phosphodiesterase in colonic neoplasias compared to normal mucosa. Gastroenterology 2000;118:A282.
    • (2000) Gastroenterology , vol.118
    • Piazza, G.A.1    Xu, S.2    Klein-Szanto, A.3
  • 24
    • 0035872448 scopus 로고    scopus 로고
    • Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis
    • Piazza GA, Thompson WJ, Pamukcu R, et al. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis. Cancer Res 2001;61:3961-8.
    • (2001) Cancer Res , vol.61 , pp. 3961-3968
    • Piazza, G.A.1    Thompson, W.J.2    Pamukcu, R.3
  • 25
    • 0142158595 scopus 로고    scopus 로고
    • Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival
    • Whitehead CM, Earle KA, Fetter J, et al. Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival. Mol Cancer Ther 2003;2:479-88.
    • (2003) Mol Cancer Ther , vol.2 , pp. 479-488
    • Whitehead, C.M.1    Earle, K.A.2    Fetter, J.3
  • 26
    • 0034665151 scopus 로고    scopus 로고
    • Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP
    • Shailubhai K, Yu HH, Karunanandaa K, et al. Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP. Cancer Res 2000;60:5151-7.
    • (2000) Cancer Res , vol.60 , pp. 5151-5157
    • Shailubhai, K.1    Yu, H.H.2    Karunanandaa, K.3
  • 27
    • 0035300437 scopus 로고    scopus 로고
    • Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays
    • Notterman DA, Alon U, Sierk AJ, Levine AJ. Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Res 2001;61:3124-30.
    • (2001) Cancer Res , vol.61 , pp. 3124-3130
    • Notterman, D.A.1    Alon, U.2    Sierk, A.J.3    Levine, A.J.4
  • 28
    • 0032545516 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP
    • Chiche JD, Schlutsmeyer SM, Bloch DB, et al. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J Biol Chem 1998;273:34263-71.
    • (1998) J Biol Chem , vol.273 , pp. 34263-34271
    • Chiche, J.D.1    Schlutsmeyer, S.M.2    Bloch, D.B.3
  • 29
    • 0037129906 scopus 로고    scopus 로고
    • Overexpression of a constitutively active protein kinase G mutant reduces neointima formation and in-stent restenosis
    • Sinnaeve P, Chiche JD, Gillijns H, et al. Overexpression of a constitutively active protein kinase G mutant reduces neointima formation and in-stent restenosis. Circulation 2002;105:2911-6.
    • (2002) Circulation , vol.105 , pp. 2911-2916
    • Sinnaeve, P.1    Chiche, J.D.2    Gillijns, H.3
  • 30
    • 0035937175 scopus 로고    scopus 로고
    • Activation of cGMP-dependent protein kinase I β inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells
    • Fischer TA, Palmetshofer A, Gambaryan S, et al. Activation of cGMP-dependent protein kinase I β inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells. J Biol Chem 2001;276:5967-74.
    • (2001) J Biol Chem , vol.276 , pp. 5967-5974
    • Fischer, T.A.1    Palmetshofer, A.2    Gambaryan, S.3
  • 31
    • 0034234978 scopus 로고    scopus 로고
    • Exisulind induction of apoptosis involves guanosine 3′,5′ -cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated β-catenin
    • Thompson WJ, Piazza GA, Li H, et al. Exisulind induction of apoptosis involves guanosine 3′,5′-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated β-catenin. Cancer Res 2000;60:3338-42.
    • (2000) Cancer Res , vol.60 , pp. 3338-3342
    • Thompson, W.J.1    Piazza, G.A.2    Li, H.3
  • 32
    • 0033755261 scopus 로고    scopus 로고
    • Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1
    • Soh JW, Mao Y, Kim MG, et al. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1. Clin Cancer Res 2000;6: 4136-41.
    • (2000) Clin Cancer Res , vol.6 , pp. 4136-4141
    • Soh, J.W.1    Mao, Y.2    Kim, M.G.3
  • 33
    • 0036690669 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G
    • Deguchi A, Soh JW, Li H, et al. Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G. Mol Cancer Ther 2002;1:803-9.
    • (2002) Mol Cancer Ther , vol.1 , pp. 803-809
    • Deguchi, A.1    Soh, J.W.2    Li, H.3
  • 34
    • 0030747817 scopus 로고    scopus 로고
    • Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels
    • Piazza GA, Alberts DS, Hixson LJ, et al. Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. Cancer Res 1997;57:2909-15.
    • (1997) Cancer Res , vol.57 , pp. 2909-2915
    • Piazza, G.A.1    Alberts, D.S.2    Hixson, L.J.3
  • 35
    • 0034757918 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells
    • Liu L, Li H, Underwood T, et al. Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells. J Pharmacol Exp Ther 2001;299:583-92.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 583-592
    • Liu, L.1    Li, H.2    Underwood, T.3
  • 37
    • 0031759389 scopus 로고    scopus 로고
    • Abnormalities in cell cycle control in cancer and their clinical implications
    • Sgambato A, Flamini G, Cittadini A, Weinstein IB. Abnormalities in cell cycle control in cancer and their clinical implications. Tumori 1998;84:421-33.
    • (1998) Tumori , vol.84 , pp. 421-433
    • Sgambato, A.1    Flamini, G.2    Cittadini, A.3    Weinstein, I.B.4
  • 38
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science 1996;274:1672-7.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 39
    • 0034660892 scopus 로고    scopus 로고
    • The Pezcoller lecture: Cancer cell cycles revisited
    • Sherr CJ. The Pezcoller lecture: cancer cell cycles revisited. Cancer Res 2000;60: 3689-95.
    • (2000) Cancer Res , vol.60 , pp. 3689-3695
    • Sherr, C.J.1
  • 40
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 41
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21((WAF1/CIP1)) gene
    • Gartel AL, Tyner AL. Transcriptional regulation of the p21((WAF1/CIP1)) gene. Exp Cell Res 1999;246:280-9.
    • (1999) Exp Cell Res , vol.246 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 42
    • 0030030036 scopus 로고    scopus 로고
    • Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis
    • Arber N, Hibshoosh H, Moss SF, et al. Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis. Gastroenterology 1996;110:669-74.
    • (1996) Gastroenterology , vol.110 , pp. 669-674
    • Arber, N.1    Hibshoosh, H.2    Moss, S.F.3
  • 44
    • 0030949419 scopus 로고    scopus 로고
    • Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells
    • Arber N, Doki Y, Han EK, et al. Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. Cancer Res 1997;57:1569-74.
    • (1997) Cancer Res , vol.57 , pp. 1569-1574
    • Arber, N.1    Doki, Y.2    Han, E.K.3
  • 45
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
    • Sparks AB, Morin PJ, Vogelstein B, Kinzler KW. Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer. Cancer Res 1998;58:1130-4.
    • (1998) Cancer Res , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3    Kinzler, K.W.4
  • 46
    • 0033119801 scopus 로고    scopus 로고
    • β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F, β-Catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-6.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 47
    • 0033545845 scopus 로고    scopus 로고
    • The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
    • Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 1999;96:5522-7.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5522-5527
    • Shtutman, M.1    Zhurinsky, J.2    Simcha, I.3
  • 48
    • 0036830654 scopus 로고    scopus 로고
    • Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve β-catenin and cyclin D1 down-regulation
    • Li H, Liu L, David ML, et al. Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve β-catenin and cyclin D1 down-regulation. Biochem Pharmacol 2002;64:1325-36.
    • (2002) Biochem Pharmacol , vol.64 , pp. 1325-1336
    • Li, H.1    Liu, L.2    David, M.L.3
  • 49
    • 0033199317 scopus 로고    scopus 로고
    • Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
    • Van Parijs L, Refaeli Y, Lord JD, Nelson BH, Abbas AK, Baltimore D. Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death. Immunity 1999;11:281-8.
    • (1999) Immunity , vol.11 , pp. 281-288
    • Van Parijs, L.1    Refaeli, Y.2    Lord, J.D.3    Nelson, B.H.4    Abbas, A.K.5    Baltimore, D.6
  • 50
    • 0142157237 scopus 로고    scopus 로고
    • Production of ribosome components in effector CD4+ T cells is accelerated by TCR sfimulation and coordinated by ERK-MAPK
    • Asmal M, Colgan J, Naef F, et al. Production of ribosome components in effector CD4+ T cells is accelerated by TCR sfimulation and coordinated by ERK-MAPK. Immunity 2003;19:535-48.
    • (2003) Immunity , vol.19 , pp. 535-548
    • Asmal, M.1    Colgan, J.2    Naef, F.3
  • 51
    • 0028970609 scopus 로고
    • Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
    • Albanese C, Johnson J, Watanabe G, et al. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions. J Biol Chem 1995; 270:23589-97.
    • (1995) J Biol Chem , vol.270 , pp. 23589-23597
    • Albanese, C.1    Johnson, J.2    Watanabe, G.3
  • 52
    • 0037108708 scopus 로고    scopus 로고
    • Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells
    • Moon EY, Lerner A. Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells. Cancer Res 2002;62:5711-9.
    • (2002) Cancer Res , vol.62 , pp. 5711-5719
    • Moon, E.Y.1    Lerner, A.2
  • 53
    • 0035038913 scopus 로고    scopus 로고
    • Overexpression of protein kinase G using adenovirus inhibits cyclin E transcription and mesangial cell cycle
    • Hanada S, Terada Y, Inoshita S, et al. Overexpression of protein kinase G using adenovirus inhibits cyclin E transcription and mesangial cell cycle. Am J Physiol Renal Physiol 2001;280:F851-9.
    • (2001) Am J Physiol Renal Physiol , vol.280
    • Hanada, S.1    Terada, Y.2    Inoshita, S.3
  • 54
    • 0028981086 scopus 로고
    • Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues
    • el-Deiry WS, Tokino T, Waldman T, et al. Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res 1995;55:2910-9.
    • (1995) Cancer Res , vol.55 , pp. 2910-2919
    • El-Deiry, W.S.1    Tokino, T.2    Waldman, T.3
  • 55
    • 0034057086 scopus 로고    scopus 로고
    • Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway
    • Huang YQ, Li JJ, Karpatkin S. Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway. J Biol Chem 2000;275:6462-8.
    • (2000) J Biol Chem , vol.275 , pp. 6462-6468
    • Huang, Y.Q.1    Li, J.J.2    Karpatkin, S.3
  • 56
    • 0033562343 scopus 로고    scopus 로고
    • Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells
    • Xiao H, Hasegawa T, Isobe K. Both Sp1 and Sp3 are responsible for p21waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells. J Cell Biochem 1999;73:291-302.
    • (1999) J Cell Biochem , vol.73 , pp. 291-302
    • Xiao, H.1    Hasegawa, T.2    Isobe, K.3
  • 57
    • 0029976068 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein a (C/EBP a) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein
    • Timchenko NA, Wilde M, Nakanishi M, Smith JR, Darlington GJ. CCAAT/enhancer-binding protein a (C/EBP a) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. Genes Dev 1996;10:804-15.
    • (1996) Genes Dev , vol.10 , pp. 804-815
    • Timchenko, N.A.1    Wilde, M.2    Nakanishi, M.3    Smith, J.R.4    Darlington, G.J.5
  • 58
    • 0035872863 scopus 로고    scopus 로고
    • A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 α-subunit of the 20S proteasome
    • Touitou R, Richardson J, Bose S, Nakanishi M, Rivett J, Allday MJ. A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 α-subunit of the 20S proteasome. EMBO J 2001;20:2367-75.
    • (2001) EMBO J , vol.20 , pp. 2367-2375
    • Touitou, R.1    Richardson, J.2    Bose, S.3    Nakanishi, M.4    Rivett, J.5    Allday, M.J.6
  • 60
    • 0034646652 scopus 로고    scopus 로고
    • Nitric oxide increases p21(Waf1/Cip1) expression by a cGMP-dependent pathway that includes activation of extracellular signal-regulated kinase and p70(S6k)
    • Gu M, Lynch J, Brecher P. Nitric oxide increases p21(Waf1/Cip1) expression by a cGMP-dependent pathway that includes activation of extracellular signal-regulated kinase and p70(S6k). J Biol Chem 2000;275:11389-96.
    • (2000) J Biol Chem , vol.275 , pp. 11389-11396
    • Gu, M.1    Lynch, J.2    Brecher, P.3
  • 61
    • 0036594890 scopus 로고    scopus 로고
    • The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
    • Gartel AL, Tyner AL. The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther 2002;1:639-49.
    • (2002) Mol Cancer Ther , vol.1 , pp. 639-649
    • Gartel, A.L.1    Tyner, A.L.2
  • 63
    • 10244242609 scopus 로고    scopus 로고
    • WAF1/CIP1 increases the susceptibility of p53 non-functional malignant glioma cells to cisplatin-induced apoptosis
    • Kondo S, Barna BP, Kondo Y, et al. WAF1/CIP1 increases the susceptibility of p53 non-functional malignant glioma cells to cisplatin-induced apoptosis. Oncogene 1996;13:1279-85.
    • (1996) Oncogene , vol.13 , pp. 1279-1285
    • Kondo, S.1    Barna, B.P.2    Kondo, Y.3
  • 64
    • 0034624331 scopus 로고    scopus 로고
    • The p21(cip1/waf1) cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells
    • Lincet H, Poulain L, Remy JS, et al. The p21(cip1/waf1) cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells. Cancer Lett 2000;161:17-26.
    • (2000) Cancer Lett , vol.161 , pp. 17-26
    • Lincet, H.1    Poulain, L.2    Remy, J.S.3
  • 65
    • 0032126494 scopus 로고    scopus 로고
    • Transforming growth factor-β1 induces apoptotic cell death in cultured retinal endothelial cells but not pericytes: Association with decreased expression of p21waf1/cip1
    • Yan Q, Sage EH. Transforming growth factor-β1 induces apoptotic cell death in cultured retinal endothelial cells but not pericytes: association with decreased expression of p21waf1/cip1. J Cell Biochem 1998;70:70-83.
    • (1998) J Cell Biochem , vol.70 , pp. 70-83
    • Yan, Q.1    Sage, E.H.2
  • 66
    • 0034686624 scopus 로고    scopus 로고
    • 15-LOX-1: A novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells
    • Shureiqi I, Chen D, Lee JJ, et al. 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. J Natl Cancer Inst (Bethesda) 2000;92:1136-42.
    • (2000) J Natl Cancer Inst (Bethesda) , vol.92 , pp. 1136-1142
    • Shureiqi, I.1    Chen, D.2    Lee, J.J.3
  • 67
    • 0042692791 scopus 로고    scopus 로고
    • The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-δ to induce apoptosis in colorectal cancer cells
    • Shureiqi I, Jiang W, Zuo X, et al. The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-δ to induce apoptosis in colorectal cancer cells. Proc Natl Acad Sci USA 2003;100:9968-73.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9968-9973
    • Shureiqi, I.1    Jiang, W.2    Zuo, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.