-
1
-
-
0023701033
-
Molecular mechanisms of endothelium-mediated vasodilation
-
Fiscus RR. Molecular mechanisms of endothelium-mediated vasodilation. Semin Thromb Hemost 1988;14 Suppl:12-22.
-
(1988)
Semin Thromb Hemost
, vol.14
, Issue.SUPPL.
, pp. 12-22
-
-
Fiscus, R.R.1
-
2
-
-
0023752017
-
CGMP-dependent protein kinase activation in intact tissues
-
Fiscus RR, Murad F. cGMP-dependent protein kinase activation in intact tissues. Methods Enzymol 1988;159:150-159
-
(1988)
Methods Enzymol
, vol.159
, pp. 150-159
-
-
Fiscus, R.R.1
Murad, F.2
-
3
-
-
33644834949
-
Function of cGMP-dependent protein kinases as revealed by gene deletion
-
Hofmann F, Feil R, Kleppisch T, Schlossmann J. Function of cGMP-dependent protein kinases as revealed by gene deletion. Physiol Rev 2006;86:1-23.
-
(2006)
Physiol Rev
, vol.86
, pp. 1-23
-
-
Hofmann, F.1
Feil, R.2
Kleppisch, T.3
Schlossmann, J.4
-
4
-
-
32844456138
-
Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase
-
Lincoln TM, Wu X, Sellak H, Dey N, Choi CS. Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase. Front Biosci 2006;11:356-367 (Pubitemid 43253498)
-
(2006)
Frontiers in Bioscience
, vol.11
, Issue.1 P.1-446
, pp. 356-367
-
-
Lincoln, T.M.1
Wu, X.2
Sellak, H.3
Dey, N.4
Choi, C.-S.5
-
6
-
-
0022261486
-
Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta
-
DOI 10.1016/0167-4889(85)90124-7
-
Fiscus RR, Rapoport RM, Waldman SA, Murad F. Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta. Biochim Biophys Acta 1985;846:179-184 (Pubitemid 15012810)
-
(1985)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.846
, Issue.1
, pp. 179-184
-
-
Fiscus, R.R.1
Rapoport, R.M.2
Waldman, S.A.3
Murad, F.4
-
7
-
-
0028912956
-
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor
-
Barger SW, Fiscus RR, Ruth P, Hofmann F, Mattson MP. Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor. J Neurochem 1995;64:2087-2096
-
(1995)
J Neurochem
, vol.64
, pp. 2087-2096
-
-
Barger, S.W.1
Fiscus, R.R.2
Ruth, P.3
Hofmann, F.4
Mattson, M.P.5
-
8
-
-
0035847606
-
Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC12 cells
-
Fiscus RR, Tu AW, Chew SB. Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC12 cells. Neuroreport 2001;12:185-189
-
(2001)
Neuroreport
, vol.12
, pp. 185-189
-
-
Fiscus, R.R.1
Tu, A.W.2
Chew, S.B.3
-
9
-
-
0141924373
-
Preincubation with atrial natriuretic peptide protects NG108-15 cells against the toxic/proapoptotic effects of the nitric oxide donor S-nitroso-N-acetylpenicillamine
-
Cheng Chew SB, Leung PY, Fiscus RR. Preincubation with atrial natriuretic peptide protects NG108-15 cells against the toxic/proapoptotic effects of the nitric oxide donor S-nitroso-N-acetylpenicillamine. Histochem Cell Biol 2003;120:163-171
-
(2003)
Histochem Cell Biol
, vol.120
, pp. 163-171
-
-
Cheng Chew, S.B.1
Leung, P.Y.2
Fiscus, R.R.3
-
10
-
-
0036634250
-
Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells
-
Fiscus RR. Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells. Neurosignals 2002;11:175-190
-
(2002)
Neurosignals
, vol.11
, pp. 175-190
-
-
Fiscus, R.R.1
-
11
-
-
0036665112
-
Nitric oxide and cyclic GMP as pro- and anti-apoptotic agents
-
Fiscus RR, Yuen JP, Chan SL, Kwong JH, Chew SB. Nitric oxide and cyclic GMP as pro- and anti-apoptotic agents. J Card Surg 2002;17:336-339
-
(2002)
J Card Surg
, vol.17
, pp. 336-339
-
-
Fiscus, R.R.1
Yuen, J.P.2
Chan, S.L.3
Kwong, J.H.4
Chew, S.B.5
-
12
-
-
0344033734
-
Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: Anti-apoptotic effects of basal cGMP/PKG
-
Chan SL, Fiscus RR. Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG. Mol Hum Reprod 2003;9:775-783
-
(2003)
Mol Hum Reprod
, vol.9
, pp. 775-783
-
-
Chan, S.L.1
Fiscus, R.R.2
-
13
-
-
33645744133
-
Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells
-
Fraser M, Chan SL, Chan SS, Fiscus RR, Tsang BK. Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells. Oncogene 2006;25:2203-2212
-
(2006)
Oncogene
, vol.25
, pp. 2203-2212
-
-
Fraser, M.1
Chan, S.L.2
Chan, S.S.3
Fiscus, R.R.4
Tsang, B.K.5
-
14
-
-
44349175448
-
Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: Involvement in p53 regulation and cisplatin resistance
-
DOI 10.1038/sj.bjc.6604375, PII 6604375
-
Leung EL, Fraser M, Fiscus RR, Tsang BK. Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance. Br J Cancer 2008;98:1803-1809 (Pubitemid 351748840)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.11
, pp. 1803-1809
-
-
Leung, E.L.1
Fraser, M.2
Fiscus, R.R.3
Tsang, B.K.4
-
15
-
-
77951172906
-
Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells
-
In press
-
Wong JC, Fiscus RR. Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells. Cardiovasc Pathol. In press 2010.
-
(2010)
Cardiovasc Pathol.
-
-
Wong, J.C.1
Fiscus, R.R.2
-
16
-
-
0032545516
-
Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP
-
Chiche JD, Schlutsmeyer SM, Bloch DB, et al. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J Biol Chem 1998;273:34263-34271
-
(1998)
J Biol Chem
, vol.273
, pp. 34263-34271
-
-
Chiche, J.D.1
Schlutsmeyer, S.M.2
Bloch, D.B.3
-
17
-
-
1542719065
-
Quantitative analysis of the cardiac fibroblast transcriptome - Implications for NO/cGMP signaling
-
Smolenski A, Schultess J, Danielewski O, et al. Quantitative analysis of the cardiac fibroblast transcriptome - implications for NO/cGMP signaling. Genomics 2004;83:577-587
-
(2004)
Genomics
, vol.83
, pp. 577-587
-
-
Smolenski, A.1
Schultess, J.2
Danielewski, O.3
-
18
-
-
0035937175
-
Activation of cGMP-dependent protein kinase Iβ inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells
-
Fischer TA, Palmetshofer A, Gambaryan S, et al. Activation of cGMP-dependent protein kinase Iβ inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells. J Biol Chem 2001;276:5967-5974
-
(2001)
J Biol Chem
, vol.276
, pp. 5967-5974
-
-
Fischer, T.A.1
Palmetshofer, A.2
Gambaryan, S.3
-
19
-
-
2542619027
-
Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells
-
Deguchi A, Thompson WJ, Weinstein IB. Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells. Cancer Res 2004;64:3966-3973
-
(2004)
Cancer Res
, vol.64
, pp. 3966-3973
-
-
Deguchi, A.1
Thompson, W.J.2
Weinstein, I.B.3
-
20
-
-
7944237784
-
The interplay between Src family kinases and receptor tyrosine kinases
-
Bromann PA, Korkaya H, Courtneidge SA. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 2004;23:7957-7968
-
(2004)
Oncogene
, vol.23
, pp. 7957-7968
-
-
Bromann, P.A.1
Korkaya, H.2
Courtneidge, S.A.3
-
21
-
-
67649600824
-
Src promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy
-
Leung EL, Tam IY, Tin VP, et al. Src promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy. Mol Cancer Res 2009;7:923-932
-
(2009)
Mol Cancer Res
, vol.7
, pp. 923-932
-
-
Leung, E.L.1
Tam, I.Y.2
Tin, V.P.3
-
22
-
-
0038386613
-
Src family kinases in tumor progression and metastasis
-
Summy JM, Gallick GE. Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 2003;22:337-358
-
(2003)
Cancer Metastasis Rev
, vol.22
, pp. 337-358
-
-
Summy, J.M.1
Gallick, G.E.2
-
23
-
-
0037229627
-
Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers
-
Wiener JR, Windham TC, Estrella VC, et al. Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers. Gynecol Oncol 2003;88:73-79
-
(2003)
Gynecol Oncol
, vol.88
, pp. 73-79
-
-
Wiener, J.R.1
Windham, T.C.2
Estrella, V.C.3
-
24
-
-
4143066760
-
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella R, Bell DW, Haber DA, Settleman J. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 2004;305:1163-1167
-
(2004)
Science
, vol.305
, pp. 1163-1167
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
Settleman, J.4
-
25
-
-
0028303913
-
CAMP- And cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets
-
Butt E, Abel K, Krieger M, et al. cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem 1994;269:14509-14517
-
(1994)
J Biol Chem
, vol.269
, pp. 14509-14517
-
-
Butt, E.1
Abel, K.2
Krieger, M.3
-
26
-
-
42949095659
-
Atrial natriuretic peptide-initiated cGMP pathways regulate vasodilator-stimulated phosphoprotein phosphorylation and angiogenesis in vascular endothelium
-
Chen H, Levine YC, Golan DE, Michel T, Lin AJ. Atrial natriuretic peptide-initiated cGMP pathways regulate vasodilator-stimulated phosphoprotein phosphorylation and angiogenesis in vascular endothelium. J Biol Chem 2008;283:4439-4447
-
(2008)
J Biol Chem
, vol.283
, pp. 4439-4447
-
-
Chen, H.1
Levine, Y.C.2
Golan, D.E.3
Michel, T.4
Lin, A.J.5
-
27
-
-
38349132563
-
Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling
-
Isenberg JS, Romeo MJ, Yu C, et al. Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood 2008;111:613-623
-
(2008)
Blood
, vol.111
, pp. 613-623
-
-
Isenberg, J.S.1
Romeo, M.J.2
Yu, C.3
-
28
-
-
37349060695
-
Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function
-
Fraser M, Bai T, Tsang BK. Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function. Int J Cancer 2008;122:534-546
-
(2008)
Int J Cancer
, vol.122
, pp. 534-546
-
-
Fraser, M.1
Bai, T.2
Tsang, B.K.3
-
29
-
-
0034687854
-
Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iβ inhabit NO-induced cerebral dilation
-
Dostmann WR, Taylor MS, Nickl CK, Brayden JE, Frank R, Tegge WJ. Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iβ inhabit NO-induced cerebral dilation. Proc Natl Acad Sci U S A 2000;97:14772-14777
-
Proc Natl Acad Sci U S A 2000
, vol.97
, pp. 14772-14777
-
-
Dostmann, W.R.1
Taylor, M.S.2
Nickl, C.K.3
Brayden, J.E.4
Frank, R.5
Tegge, W.J.6
-
30
-
-
0035990915
-
Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Iα
-
Dostmann WR, Tegge W, Frank R, Nickl CK, Taylor MS, Brayden JE. Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Iα. Pharmacol Ther 2002;93:203-215
-
(2002)
Pharmacol Ther
, vol.93
, pp. 203-215
-
-
Dostmann, W.R.1
Tegge, W.2
Frank, R.3
Nickl, C.K.4
Taylor, M.S.5
Brayden, J.E.6
-
31
-
-
2142650232
-
Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation
-
Taylor MS, Okwuchukwuasanya C, Nickl CK, Tegge W, Brayden JE, Dostmann WR. Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation. Mol Pharmacol 2004;65:1111-1119
-
(2004)
Mol Pharmacol
, vol.65
, pp. 1111-1119
-
-
Taylor, M.S.1
Okwuchukwuasanya, C.2
Nickl, C.K.3
Tegge, W.4
Brayden, J.E.5
Dostmann, W.R.6
-
32
-
-
0033761255
-
Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells
-
Alper O, De Santis ML, Stromberg K, Hacker NF, Cho-Chung YS, Salomon DS. Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells. Int J Cancer 2000;88:566-574
-
(2000)
Int J Cancer
, vol.88
, pp. 566-574
-
-
Alper, O.1
De Santis, M.L.2
Stromberg, K.3
Hacker, N.F.4
Cho-Chung, Y.S.5
Salomon, D.S.6
-
33
-
-
24944553762
-
Stromal cell-derived factor-1α (SDF-1α/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation
-
Porcile C, Bajetto A, Barbieri F, et al. Stromal cell-derived factor-1α (SDF-1α/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. Exp Cell Res 2005;308:241-253
-
(2005)
Exp Cell Res
, vol.308
, pp. 241-253
-
-
Porcile, C.1
Bajetto, A.2
Barbieri, F.3
-
34
-
-
27544453151
-
SRC family kinase activity is required for murine embryonic stem cell growth and differentiation
-
Meyn MA 3rd, Schreiner SJ, Dumitrescu TP, Nau GJ, Smithgall TE. SRC family kinase activity is required for murine embryonic stem cell growth and differentiation. Mol Pharmacol 2005;68:1320-1330
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1320-1330
-
-
Meyn III, M.A.1
Schreiner, S.J.2
Dumitrescu, T.P.3
Nau, G.J.4
Smithgall, T.E.5
-
35
-
-
0035912929
-
Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines
-
Tian G, Cory M, Smith AA, Knight WB. Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochemistry 2001;40:7084-7091
-
(2001)
Biochemistry
, vol.40
, pp. 7084-7091
-
-
Tian, G.1
Cory, M.2
Smith, A.A.3
Knight, W.B.4
-
36
-
-
34247480545
-
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
-
DOI 10.1038/nrc2106, PII NRC2106
-
Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007;7:332-344 (Pubitemid 46652481)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.5
, pp. 332-344
-
-
Force, T.1
Krause, D.S.2
Van Etten, R.A.3
-
38
-
-
0032483514
-
Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells
-
Hood J, Granger HJ. Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J Biol Chem 1998;273:23504-23508
-
(1998)
J Biol Chem
, vol.273
, pp. 23504-23508
-
-
Hood, J.1
Granger, H.J.2
-
39
-
-
0034668186
-
New insights into p53 regulation and gene therapy for cancer
-
Zeimet AG, Riha K, Berger J, et al. New insights into p53 regulation and gene therapy for cancer. Biochem Pharmacol 2000;60:1153-1163
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1153-1163
-
-
Zeimet, A.G.1
Riha, K.2
Berger, J.3
-
40
-
-
0034910880
-
Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium
-
Wong AS, Kim SO, Leung PC, Auersperg N, Pelech SL. Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium. Gynecol Oncol 2001;82:305-311
-
(2001)
Gynecol Oncol
, vol.82
, pp. 305-311
-
-
Wong, A.S.1
Kim, S.O.2
Leung, P.C.3
Auersperg, N.4
Pelech, S.L.5
-
41
-
-
0037429737
-
Epidermal growth factor receptor: Mechanisms of activation and signalling
-
Jorissen RN, Walker F, Pouliot N, Garrett TP, Ward CW, Burgess AW. Epidermal growth factor receptor: mechanisms of activation and signalling. Exp Cell Res 2003;284:31-53.
-
(2003)
Exp Cell Res
, vol.284
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
Garrett, T.P.4
Ward, C.W.5
Burgess, A.W.6
-
42
-
-
2042446388
-
Nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1
-
Tejedo JR, Cahuana GM, Ramirez R, et al. Nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1. Endocrinology 2004;145:2319-2327
-
(2004)
Endocrinology
, vol.145
, pp. 2319-2327
-
-
Tejedo, J.R.1
Cahuana, G.M.2
Ramirez, R.3
-
43
-
-
0034808675
-
Evidence for involvement of c-Src in the anti-apoptotic action of nitric oxide in serum-deprived RINm5F cells
-
Tejedo JR, Ramirez R, Cahuana GM, Rincon P, Sobrino F, Bedoya FJ. Evidence for involvement of c-Src in the anti-apoptotic action of nitric oxide in serum-deprived RINm5F cells. Cell Signal 2001;13: 809-817
-
(2001)
Cell Signal
, vol.13
, pp. 809-817
-
-
Tejedo, J.R.1
Ramirez, R.2
Cahuana, G.M.3
Rincon, P.4
Sobrino, F.5
Bedoya, F.J.6
|