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Volumn 8, Issue 4, 2010, Pages 578-591

Protein kinase G type Iα activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; 4 (4' PHENOXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE 1 ALPHA; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR DT2; EPIDERMAL GROWTH FACTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 77951150727     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-09-0178     Document Type: Article
Times cited : (56)

References (43)
  • 1
    • 0023701033 scopus 로고
    • Molecular mechanisms of endothelium-mediated vasodilation
    • Fiscus RR. Molecular mechanisms of endothelium-mediated vasodilation. Semin Thromb Hemost 1988;14 Suppl:12-22.
    • (1988) Semin Thromb Hemost , vol.14 , Issue.SUPPL. , pp. 12-22
    • Fiscus, R.R.1
  • 2
    • 0023752017 scopus 로고
    • CGMP-dependent protein kinase activation in intact tissues
    • Fiscus RR, Murad F. cGMP-dependent protein kinase activation in intact tissues. Methods Enzymol 1988;159:150-159
    • (1988) Methods Enzymol , vol.159 , pp. 150-159
    • Fiscus, R.R.1    Murad, F.2
  • 3
    • 33644834949 scopus 로고    scopus 로고
    • Function of cGMP-dependent protein kinases as revealed by gene deletion
    • Hofmann F, Feil R, Kleppisch T, Schlossmann J. Function of cGMP-dependent protein kinases as revealed by gene deletion. Physiol Rev 2006;86:1-23.
    • (2006) Physiol Rev , vol.86 , pp. 1-23
    • Hofmann, F.1    Feil, R.2    Kleppisch, T.3    Schlossmann, J.4
  • 4
    • 32844456138 scopus 로고    scopus 로고
    • Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase
    • Lincoln TM, Wu X, Sellak H, Dey N, Choi CS. Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase. Front Biosci 2006;11:356-367 (Pubitemid 43253498)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.1 P.1-446 , pp. 356-367
    • Lincoln, T.M.1    Wu, X.2    Sellak, H.3    Dey, N.4    Choi, C.-S.5
  • 6
    • 0022261486 scopus 로고
    • Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta
    • DOI 10.1016/0167-4889(85)90124-7
    • Fiscus RR, Rapoport RM, Waldman SA, Murad F. Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta. Biochim Biophys Acta 1985;846:179-184 (Pubitemid 15012810)
    • (1985) Biochimica et Biophysica Acta - Molecular Cell Research , vol.846 , Issue.1 , pp. 179-184
    • Fiscus, R.R.1    Rapoport, R.M.2    Waldman, S.A.3    Murad, F.4
  • 7
    • 0028912956 scopus 로고
    • Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor
    • Barger SW, Fiscus RR, Ruth P, Hofmann F, Mattson MP. Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of β-amyloid precursor. J Neurochem 1995;64:2087-2096
    • (1995) J Neurochem , vol.64 , pp. 2087-2096
    • Barger, S.W.1    Fiscus, R.R.2    Ruth, P.3    Hofmann, F.4    Mattson, M.P.5
  • 8
    • 0035847606 scopus 로고    scopus 로고
    • Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC12 cells
    • Fiscus RR, Tu AW, Chew SB. Natriuretic peptides inhibit apoptosis and prolong the survival of serum-deprived PC12 cells. Neuroreport 2001;12:185-189
    • (2001) Neuroreport , vol.12 , pp. 185-189
    • Fiscus, R.R.1    Tu, A.W.2    Chew, S.B.3
  • 9
    • 0141924373 scopus 로고    scopus 로고
    • Preincubation with atrial natriuretic peptide protects NG108-15 cells against the toxic/proapoptotic effects of the nitric oxide donor S-nitroso-N-acetylpenicillamine
    • Cheng Chew SB, Leung PY, Fiscus RR. Preincubation with atrial natriuretic peptide protects NG108-15 cells against the toxic/proapoptotic effects of the nitric oxide donor S-nitroso-N-acetylpenicillamine. Histochem Cell Biol 2003;120:163-171
    • (2003) Histochem Cell Biol , vol.120 , pp. 163-171
    • Cheng Chew, S.B.1    Leung, P.Y.2    Fiscus, R.R.3
  • 10
    • 0036634250 scopus 로고    scopus 로고
    • Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells
    • Fiscus RR. Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells. Neurosignals 2002;11:175-190
    • (2002) Neurosignals , vol.11 , pp. 175-190
    • Fiscus, R.R.1
  • 12
    • 0344033734 scopus 로고    scopus 로고
    • Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: Anti-apoptotic effects of basal cGMP/PKG
    • Chan SL, Fiscus RR. Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG. Mol Hum Reprod 2003;9:775-783
    • (2003) Mol Hum Reprod , vol.9 , pp. 775-783
    • Chan, S.L.1    Fiscus, R.R.2
  • 13
    • 33645744133 scopus 로고    scopus 로고
    • Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells
    • Fraser M, Chan SL, Chan SS, Fiscus RR, Tsang BK. Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells. Oncogene 2006;25:2203-2212
    • (2006) Oncogene , vol.25 , pp. 2203-2212
    • Fraser, M.1    Chan, S.L.2    Chan, S.S.3    Fiscus, R.R.4    Tsang, B.K.5
  • 14
    • 44349175448 scopus 로고    scopus 로고
    • Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: Involvement in p53 regulation and cisplatin resistance
    • DOI 10.1038/sj.bjc.6604375, PII 6604375
    • Leung EL, Fraser M, Fiscus RR, Tsang BK. Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement in p53 regulation and cisplatin resistance. Br J Cancer 2008;98:1803-1809 (Pubitemid 351748840)
    • (2008) British Journal of Cancer , vol.98 , Issue.11 , pp. 1803-1809
    • Leung, E.L.1    Fraser, M.2    Fiscus, R.R.3    Tsang, B.K.4
  • 15
    • 77951172906 scopus 로고    scopus 로고
    • Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells
    • In press
    • Wong JC, Fiscus RR. Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells. Cardiovasc Pathol. In press 2010.
    • (2010) Cardiovasc Pathol.
    • Wong, J.C.1    Fiscus, R.R.2
  • 16
    • 0032545516 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP
    • Chiche JD, Schlutsmeyer SM, Bloch DB, et al. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP. J Biol Chem 1998;273:34263-34271
    • (1998) J Biol Chem , vol.273 , pp. 34263-34271
    • Chiche, J.D.1    Schlutsmeyer, S.M.2    Bloch, D.B.3
  • 17
    • 1542719065 scopus 로고    scopus 로고
    • Quantitative analysis of the cardiac fibroblast transcriptome - Implications for NO/cGMP signaling
    • Smolenski A, Schultess J, Danielewski O, et al. Quantitative analysis of the cardiac fibroblast transcriptome - implications for NO/cGMP signaling. Genomics 2004;83:577-587
    • (2004) Genomics , vol.83 , pp. 577-587
    • Smolenski, A.1    Schultess, J.2    Danielewski, O.3
  • 18
    • 0035937175 scopus 로고    scopus 로고
    • Activation of cGMP-dependent protein kinase Iβ inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells
    • Fischer TA, Palmetshofer A, Gambaryan S, et al. Activation of cGMP-dependent protein kinase Iβ inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells. J Biol Chem 2001;276:5967-5974
    • (2001) J Biol Chem , vol.276 , pp. 5967-5974
    • Fischer, T.A.1    Palmetshofer, A.2    Gambaryan, S.3
  • 19
    • 2542619027 scopus 로고    scopus 로고
    • Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells
    • Deguchi A, Thompson WJ, Weinstein IB. Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells. Cancer Res 2004;64:3966-3973
    • (2004) Cancer Res , vol.64 , pp. 3966-3973
    • Deguchi, A.1    Thompson, W.J.2    Weinstein, I.B.3
  • 20
    • 7944237784 scopus 로고    scopus 로고
    • The interplay between Src family kinases and receptor tyrosine kinases
    • Bromann PA, Korkaya H, Courtneidge SA. The interplay between Src family kinases and receptor tyrosine kinases. Oncogene 2004;23:7957-7968
    • (2004) Oncogene , vol.23 , pp. 7957-7968
    • Bromann, P.A.1    Korkaya, H.2    Courtneidge, S.A.3
  • 21
    • 67649600824 scopus 로고    scopus 로고
    • Src promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy
    • Leung EL, Tam IY, Tin VP, et al. Src promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy. Mol Cancer Res 2009;7:923-932
    • (2009) Mol Cancer Res , vol.7 , pp. 923-932
    • Leung, E.L.1    Tam, I.Y.2    Tin, V.P.3
  • 22
    • 0038386613 scopus 로고    scopus 로고
    • Src family kinases in tumor progression and metastasis
    • Summy JM, Gallick GE. Src family kinases in tumor progression and metastasis. Cancer Metastasis Rev 2003;22:337-358
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 337-358
    • Summy, J.M.1    Gallick, G.E.2
  • 23
    • 0037229627 scopus 로고    scopus 로고
    • Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers
    • Wiener JR, Windham TC, Estrella VC, et al. Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers. Gynecol Oncol 2003;88:73-79
    • (2003) Gynecol Oncol , vol.88 , pp. 73-79
    • Wiener, J.R.1    Windham, T.C.2    Estrella, V.C.3
  • 24
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
    • Sordella R, Bell DW, Haber DA, Settleman J. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 2004;305:1163-1167
    • (2004) Science , vol.305 , pp. 1163-1167
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3    Settleman, J.4
  • 25
    • 0028303913 scopus 로고
    • CAMP- And cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets
    • Butt E, Abel K, Krieger M, et al. cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem 1994;269:14509-14517
    • (1994) J Biol Chem , vol.269 , pp. 14509-14517
    • Butt, E.1    Abel, K.2    Krieger, M.3
  • 26
    • 42949095659 scopus 로고    scopus 로고
    • Atrial natriuretic peptide-initiated cGMP pathways regulate vasodilator-stimulated phosphoprotein phosphorylation and angiogenesis in vascular endothelium
    • Chen H, Levine YC, Golan DE, Michel T, Lin AJ. Atrial natriuretic peptide-initiated cGMP pathways regulate vasodilator-stimulated phosphoprotein phosphorylation and angiogenesis in vascular endothelium. J Biol Chem 2008;283:4439-4447
    • (2008) J Biol Chem , vol.283 , pp. 4439-4447
    • Chen, H.1    Levine, Y.C.2    Golan, D.E.3    Michel, T.4    Lin, A.J.5
  • 27
    • 38349132563 scopus 로고    scopus 로고
    • Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling
    • Isenberg JS, Romeo MJ, Yu C, et al. Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood 2008;111:613-623
    • (2008) Blood , vol.111 , pp. 613-623
    • Isenberg, J.S.1    Romeo, M.J.2    Yu, C.3
  • 28
    • 37349060695 scopus 로고    scopus 로고
    • Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function
    • Fraser M, Bai T, Tsang BK. Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function. Int J Cancer 2008;122:534-546
    • (2008) Int J Cancer , vol.122 , pp. 534-546
    • Fraser, M.1    Bai, T.2    Tsang, B.K.3
  • 29
    • 0034687854 scopus 로고    scopus 로고
    • Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iβ inhabit NO-induced cerebral dilation
    • Dostmann WR, Taylor MS, Nickl CK, Brayden JE, Frank R, Tegge WJ. Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iβ inhabit NO-induced cerebral dilation. Proc Natl Acad Sci U S A 2000;97:14772-14777
    • Proc Natl Acad Sci U S A 2000 , vol.97 , pp. 14772-14777
    • Dostmann, W.R.1    Taylor, M.S.2    Nickl, C.K.3    Brayden, J.E.4    Frank, R.5    Tegge, W.J.6
  • 30
    • 0035990915 scopus 로고    scopus 로고
    • Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Iα
    • Dostmann WR, Tegge W, Frank R, Nickl CK, Taylor MS, Brayden JE. Exploring the mechanisms of vascular smooth muscle tone with highly specific, membrane-permeable inhibitors of cyclic GMP-dependent protein kinase Iα. Pharmacol Ther 2002;93:203-215
    • (2002) Pharmacol Ther , vol.93 , pp. 203-215
    • Dostmann, W.R.1    Tegge, W.2    Frank, R.3    Nickl, C.K.4    Taylor, M.S.5    Brayden, J.E.6
  • 31
    • 2142650232 scopus 로고    scopus 로고
    • Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation
    • Taylor MS, Okwuchukwuasanya C, Nickl CK, Tegge W, Brayden JE, Dostmann WR. Inhibition of cGMP-dependent protein kinase by the cell-permeable peptide DT-2 reveals a novel mechanism of vasoregulation. Mol Pharmacol 2004;65:1111-1119
    • (2004) Mol Pharmacol , vol.65 , pp. 1111-1119
    • Taylor, M.S.1    Okwuchukwuasanya, C.2    Nickl, C.K.3    Tegge, W.4    Brayden, J.E.5    Dostmann, W.R.6
  • 32
    • 0033761255 scopus 로고    scopus 로고
    • Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells
    • Alper O, De Santis ML, Stromberg K, Hacker NF, Cho-Chung YS, Salomon DS. Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells. Int J Cancer 2000;88:566-574
    • (2000) Int J Cancer , vol.88 , pp. 566-574
    • Alper, O.1    De Santis, M.L.2    Stromberg, K.3    Hacker, N.F.4    Cho-Chung, Y.S.5    Salomon, D.S.6
  • 33
    • 24944553762 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1α (SDF-1α/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation
    • Porcile C, Bajetto A, Barbieri F, et al. Stromal cell-derived factor-1α (SDF-1α/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. Exp Cell Res 2005;308:241-253
    • (2005) Exp Cell Res , vol.308 , pp. 241-253
    • Porcile, C.1    Bajetto, A.2    Barbieri, F.3
  • 34
    • 27544453151 scopus 로고    scopus 로고
    • SRC family kinase activity is required for murine embryonic stem cell growth and differentiation
    • Meyn MA 3rd, Schreiner SJ, Dumitrescu TP, Nau GJ, Smithgall TE. SRC family kinase activity is required for murine embryonic stem cell growth and differentiation. Mol Pharmacol 2005;68:1320-1330
    • (2005) Mol Pharmacol , vol.68 , pp. 1320-1330
    • Meyn III, M.A.1    Schreiner, S.J.2    Dumitrescu, T.P.3    Nau, G.J.4    Smithgall, T.E.5
  • 35
    • 0035912929 scopus 로고    scopus 로고
    • Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines
    • Tian G, Cory M, Smith AA, Knight WB. Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochemistry 2001;40:7084-7091
    • (2001) Biochemistry , vol.40 , pp. 7084-7091
    • Tian, G.1    Cory, M.2    Smith, A.A.3    Knight, W.B.4
  • 36
    • 34247480545 scopus 로고    scopus 로고
    • Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
    • DOI 10.1038/nrc2106, PII NRC2106
    • Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007;7:332-344 (Pubitemid 46652481)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.5 , pp. 332-344
    • Force, T.1    Krause, D.S.2    Van Etten, R.A.3
  • 38
    • 0032483514 scopus 로고    scopus 로고
    • Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells
    • Hood J, Granger HJ. Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J Biol Chem 1998;273:23504-23508
    • (1998) J Biol Chem , vol.273 , pp. 23504-23508
    • Hood, J.1    Granger, H.J.2
  • 39
    • 0034668186 scopus 로고    scopus 로고
    • New insights into p53 regulation and gene therapy for cancer
    • Zeimet AG, Riha K, Berger J, et al. New insights into p53 regulation and gene therapy for cancer. Biochem Pharmacol 2000;60:1153-1163
    • (2000) Biochem Pharmacol , vol.60 , pp. 1153-1163
    • Zeimet, A.G.1    Riha, K.2    Berger, J.3
  • 40
    • 0034910880 scopus 로고    scopus 로고
    • Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium
    • Wong AS, Kim SO, Leung PC, Auersperg N, Pelech SL. Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium. Gynecol Oncol 2001;82:305-311
    • (2001) Gynecol Oncol , vol.82 , pp. 305-311
    • Wong, A.S.1    Kim, S.O.2    Leung, P.C.3    Auersperg, N.4    Pelech, S.L.5
  • 42
    • 2042446388 scopus 로고    scopus 로고
    • Nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1
    • Tejedo JR, Cahuana GM, Ramirez R, et al. Nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1. Endocrinology 2004;145:2319-2327
    • (2004) Endocrinology , vol.145 , pp. 2319-2327
    • Tejedo, J.R.1    Cahuana, G.M.2    Ramirez, R.3
  • 43
    • 0034808675 scopus 로고    scopus 로고
    • Evidence for involvement of c-Src in the anti-apoptotic action of nitric oxide in serum-deprived RINm5F cells
    • Tejedo JR, Ramirez R, Cahuana GM, Rincon P, Sobrino F, Bedoya FJ. Evidence for involvement of c-Src in the anti-apoptotic action of nitric oxide in serum-deprived RINm5F cells. Cell Signal 2001;13: 809-817
    • (2001) Cell Signal , vol.13 , pp. 809-817
    • Tejedo, J.R.1    Ramirez, R.2    Cahuana, G.M.3    Rincon, P.4    Sobrino, F.5    Bedoya, F.J.6


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