-
1
-
-
77951220203
-
Trypanosoma cruzi induces the reactive oxygen species-parp-1-rela pathway for up-regulation of cytokine expression in cardiomyocytes
-
Ba X, Gupta S, Davidson M, Garg NJ. (2010). Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes. J Biol Chem 285: 11596-11606.
-
(2010)
J Biol Chem
, vol.285
, pp. 11596-11606
-
-
Ba, X.1
Gupta, S.2
Davidson, M.3
Garg, N.J.4
-
2
-
-
77956147463
-
Characterization of fra7b, a human common fragile site mapped at the 7P chromosome terminal region
-
Bosco N, Pelliccia F, Rocchi A. (2010). Characterization of FRA7B, a human common fragile site mapped at the 7p chromosome terminal region. Cancer Genet Cytogenet 202: 47-52.
-
(2010)
Cancer Genet Cytogenet
, vol.202
, pp. 47-52
-
-
Bosco, N.1
Pelliccia, F.2
Rocchi, A.3
-
3
-
-
8644282751
-
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
-
DOI 10.1128/MCB.24.23.10161-10168.2004
-
Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N et al. (2004). Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 24: 10161-10168. (Pubitemid 39507856)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.23
, pp. 10161-10168
-
-
Deng, J.1
Lu, P.D.2
Zhang, Y.3
Scheuner, D.4
Kaufman, R.J.5
Sonenberg, N.6
Harding, H.P.7
Ron, D.8
-
4
-
-
0038673854
-
STAT signaling in cancer: Insights into pathogenesis and treatment strategies
-
Frank DA. (2003). STAT signaling in cancer: insights into pathogenesis and treatment strategies. Cancer Treat Res 115: 267-291.
-
(2003)
Cancer Treat Res
, vol.115
, pp. 267-291
-
-
Frank, D.A.1
-
5
-
-
34548313955
-
Clonogenic assay of cells in vitro
-
Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C. (2006). Clonogenic assay of cells in vitro. Nat Protoc 1: 2315-2319.
-
(2006)
Nat Protoc
, vol.1
, pp. 2315-2319
-
-
Franken, N.A.1
Rodermond, H.M.2
Stap, J.3
Haveman, J.4
Van Bree, C.5
-
6
-
-
0026708394
-
Independent modes of transcriptional activation by the p50 and p65 subunits of nf-kappa B
-
Fujita T, Nolan GP, Ghosh S, Baltimore D. (1992). Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Genes Dev 6: 775-787.
-
(1992)
Genes Dev
, vol.6
, pp. 775-787
-
-
Fujita, T.1
Nolan, G.P.2
Ghosh, S.3
Baltimore, D.4
-
7
-
-
1442334863
-
Von Willebrand factor as an intermediate between hemostasis and angiogenesis of tumor origin
-
Gil-Bazo I, Catalan V, Paramo J, Quero C, Escriva de Romani S, Perez-Ochoa A et al. (2003). Von Willebrand factor as an intermediate between hemostasis and angiogenesis of tumor origin. Rev Med Univ Navarra 47: 22-28.
-
(2003)
Rev Med Univ Navarra
, vol.47
, pp. 22-28
-
-
Gil-Bazo, I.1
Catalan, V.2
Paramo, J.3
Quero, C.4
Escriva De Romani, S.5
Perez-Ochoa, A.6
-
8
-
-
33748433789
-
Restoration of SHIP-1 activity in human leukemic cells modifies NF-κB activation pathway and cellular survival upon oxidative stress
-
DOI 10.1038/sj.onc.1209542, PII 1209542
-
Gloire G, Charlier E, Rahmouni S, Volanti C, Chariot A, Erneux C et al. (2006). Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappa B activation pathway and cellular survival upon oxidative stress. Oncogene 25: 5485-5494. (Pubitemid 44344099)
-
(2006)
Oncogene
, vol.25
, Issue.40
, pp. 5485-5494
-
-
Gloire, G.1
Charlier, E.2
Rahmouni, S.3
Volanti, C.4
Chariot, A.5
Erneux, C.6
Piette, J.7
-
9
-
-
33750902737
-
The endoplasmic reticulum: Folding, calcium homeostasis, signaling, and redox control
-
DOI 10.1089/ars.2006.8.1391
-
Gorlach A, Klappa P, Kietzmann T. (2006). The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid Redox Signal 8: 1391-1418. (Pubitemid 44726319)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.9-10
, pp. 1391-1418
-
-
Gorlach, A.1
Klappa, P.2
Kietzmann, T.3
-
10
-
-
79953107993
-
A brief history of il-9
-
Goswami R, Kaplan MH. (2011). A brief history of IL-9. J Immunol 186: 3283-3288.
-
(2011)
J Immunol
, vol.186
, pp. 3283-3288
-
-
Goswami, R.1
Kaplan, M.H.2
-
11
-
-
77549083560
-
Dangerous liaisons: STAT3 and NF-kappa B collaboration and crosstalk in cancer
-
Grivennikov SI, Karin M. (2009). Dangerous liaisons: STAT3 and NF-kappa B collaboration and crosstalk in cancer. Cytokine Growth Factor Rev 21: 11-19.
-
(2009)
Cytokine Growth Factor Rev
, vol.21
, pp. 11-19
-
-
Grivennikov, S.I.1
Karin, M.2
-
12
-
-
52949096859
-
The function of stat3 in tumor cells and their microenvironment
-
Groner B, Lucks P, Borghouts C. (2008). The function of Stat3 in tumor cells and their microenvironment. Semin Cell Dev Biol 19: 341-350.
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 341-350
-
-
Groner, B.1
Lucks, P.2
Borghouts, C.3
-
13
-
-
34548037901
-
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
-
DOI 10.1038/sj.cdd.4402200, PII 4402200
-
Hoyer-Hansen M, Jaattela M. (2007). Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ 14: 1576-1582. (Pubitemid 47278843)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1576-1582
-
-
Hoyer-Hansen, M.1
Jaattela, M.2
-
14
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through ire1alphamediated nf-kappa B activation and down-regulation of TRAF2 expression
-
Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH. (2006). Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alphamediated NF-kappa B activation and down-regulation of TRAF2 expression. Mol Cell Biol 26: 3071-3084.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
15
-
-
70350778443
-
An epigenetic switch involving NF-kappa B, Lin28, Let-7 microrna, and IL6 links inflammation to cell transformation
-
Iliopoulos D, Hirsch HA, Struhl K. (2009). An epigenetic switch involving NF-kappa B, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 139: 693-706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
16
-
-
69249111865
-
Targeting adam12 in human disease: Head, body or tail?
-
Jacobsen J, Wewer UM. (2009). Targeting ADAM12 in human disease: head, body or tail? Curr Pharm Des 15: 2300-2310.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 2300-2310
-
-
Jacobsen, J.1
Wewer, U.M.2
-
17
-
-
12844259491
-
GCN2 phosphorylation of eIF2α activates NF-κB in response to UV irradiation
-
DOI 10.1042/BJ20041164
-
Jiang HY, Wek RC. (2005). GCN2 phosphorylation of eIF2 alpha activates NF-kappa B in response to UV irradiation. Biochem J 385 (Pt 2): 371-380. (Pubitemid 40165069)
-
(2005)
Biochemical Journal
, vol.385
, Issue.2
, pp. 371-380
-
-
Jiang, H.-Y.1
Wek, R.C.2
-
18
-
-
14844327760
-
Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
DOI 10.1016/j.cell.2004.12.041
-
Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M. (2005). Reactive oxygen species promote TNF alpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120: 649-661. (Pubitemid 40343077)
-
(2005)
Cell
, vol.120
, Issue.5
, pp. 649-661
-
-
Kamata, H.1
Honda, S.-I.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
19
-
-
57249104900
-
Nf-kappa B activates transcription of the RNA-binding factor hur, via PI3K-AKT signaling, to promote gastric tumorigenesis
-
2042 e2031-2033
-
Kang MJ, Ryu BK, Lee MG, Han J, Lee JH, Ha TK et al. (2008). NF-kappa B activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis. Gastroenterology 135: 2030-2042 2042 e2031-2033.
-
(2008)
Gastroenterology
, vol.135
, pp. 2030-2042
-
-
Kang, M.J.1
Ryu, B.K.2
Lee, M.G.3
Han, J.4
Lee, J.H.5
Ha, T.K.6
-
20
-
-
33744978564
-
Nf-kappa B and cancer: Mechanisms and targets
-
Karin M. (2006). NF-kappa B and cancer: mechanisms and targets. Mol Carcinog 45: 355-361.
-
(2006)
Mol Carcinog
, vol.45
, pp. 355-361
-
-
Karin, M.1
-
21
-
-
0036009115
-
Nf-kappa B at the crossroads of life and death
-
Karin M, Lin A. (2002). NF-kappa B at the crossroads of life and death. Nat Immunol 3: 221-227.
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
22
-
-
77956727472
-
Post-transcriptional control during chronic inflammation and cancer: A focus on au-rich elements
-
Khabar KS. (2010). Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements. Cell Mol Life Sci 67: 2937-2955.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 2937-2955
-
-
Khabar, K.S.1
-
23
-
-
72049124015
-
Atf4-dependent transcription mediates signaling of amino acid limitation
-
Kilberg MS, Shan J, Su N. (2009). ATF4-dependent transcription mediates signaling of amino acid limitation. Trends Endocrinol Metab 20: 436-443.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 436-443
-
-
Kilberg, M.S.1
Shan, J.2
Su, N.3
-
24
-
-
68949214606
-
Biphasic, bidirectional regulation of NF-kappa B by endoplasmic reticulum stress
-
Kitamura M. (2009). Biphasic, bidirectional regulation of NF-kappa B by endoplasmic reticulum stress. Antioxid Redox Signal 11: 2353-2364.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2353-2364
-
-
Kitamura, M.1
-
25
-
-
63249092765
-
Persistently activated stat3 maintains constitutive NF-kappa B activity in tumors
-
Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z et al. (2009). Persistently activated Stat3 maintains constitutive NF-kappa B activity in tumors. Cancer Cell 15: 283-293.
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
Kujawski, M.4
Niu, G.5
Li, Z.6
-
26
-
-
35649021332
-
NADPH Oxidase Promotes Pancreatic Cancer Cell Survival via Inhibiting JAK2 Dephosphorylation by Tyrosine Phosphatases
-
DOI 10.1053/j.gastro.2007.08.022, PII S0016508507014795
-
Lee JK, Edderkaoui M, Truong P, Ohno I, Jang KT, Berti A et al. (2007). NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases. Gastroenterology 133: 1637-1648. (Pubitemid 350029743)
-
(2007)
Gastroenterology
, vol.133
, Issue.5
, pp. 1637-1648
-
-
Lee, J.K.1
Edderkaoui, M.2
Truong, P.3
Ohno, I.4
Jang, K.5
Berti, A.6
Pandol, S.J.7
Gukovskaya, A.S.8
-
27
-
-
49949105827
-
The unfolded protein response regulator grp78/bip is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
-
Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS. (2008). The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death Differ 15: 1460-1471.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1460-1471
-
-
Li, J.1
Ni, M.2
Lee, B.3
Barron, E.4
Hinton, D.R.5
Lee, A.S.6
-
28
-
-
36049049392
-
IRE1 signaling affects cell fate during the unfolded protein response
-
DOI 10.1126/science.1146361
-
Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B et al. (2007). IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944-949. (Pubitemid 350098984)
-
(2007)
Science
, vol.318
, Issue.5852
, pp. 944-949
-
-
Lin, J.H.1
Li, H.2
Yasumura, D.3
Cohen, H.R.4
Zhang, C.5
Panning, B.6
Shokat, K.M.7
LaVail, M.M.8
Walter, P.9
-
29
-
-
33749492425
-
Endoplasmic reticulum stress signaling in disease
-
DOI 10.1152/physrev.00015.2006
-
Marciniak SJ, Ron D. (2006). Endoplasmic reticulum stress signaling in disease. Physiol Rev 86: 1133-1149. (Pubitemid 44521649)
-
(2006)
Physiological Reviews
, vol.86
, Issue.4
, pp. 1133-1149
-
-
Marciniak, S.J.1
Ron, D.2
-
30
-
-
77958114292
-
A novel axis of innate immunity in cancer
-
Mattarollo SR, Smyth MJ. (2010). A novel axis of innate immunity in cancer. Nat Immunol 11: 981-982.
-
(2010)
Nat Immunol
, vol.11
, pp. 981-982
-
-
Mattarollo, S.R.1
Smyth, M.J.2
-
31
-
-
33847351136
-
The JAK-STAT signaling pathway: Input and output integration
-
Murray PJ. (2007). The JAK-STAT signaling pathway: input and output integration. J Immunol 178: 2623-2629. (Pubitemid 46333135)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2623-2629
-
-
Murray, P.J.1
-
32
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
DOI 10.1038/sj.cdd.4401373
-
Oyadomari S, Mori M. (2004). Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11: 381-389. (Pubitemid 38489416)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
33
-
-
0030603101
-
2+ and reactive oxygen intermediates as messengers
-
DOI 10.1016/0014-5793(96)00800-9
-
2+ and reactive oxygen intermediates as messengers. FEBS Lett 392: 129-136. (Pubitemid 26276734)
-
(1996)
FEBS Letters
, vol.392
, Issue.2
, pp. 129-136
-
-
Pahl, H.L.1
Baeuerle, P.A.2
-
34
-
-
3242723975
-
3H]uridine incorporation and stress-dependent transcription
-
DOI 10.1021/bi049358o
-
2+ buffer BAPTA. Analyses of 3Huridine incorporation and stress-dependent transcription. Biochemistry 43: 9576-9582. (Pubitemid 38955491)
-
(2004)
Biochemistry
, vol.43
, Issue.29
, pp. 9576-9582
-
-
Shang, J.1
Lehrman, M.A.2
-
36
-
-
4544312319
-
The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis
-
DOI 10.1073/pnas.0402760101
-
Smyth I, Du X, Taylor MS, Justice MJ, Beutler B, Jackson IJ. (2004). The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci USA 101: 13560-13565. (Pubitemid 39238442)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.37
, pp. 13560-13565
-
-
Smyth, I.1
Du, X.2
Taylor, M.S.3
Justice, M.J.4
Beutler, B.5
Jackson, I.J.6
-
37
-
-
64549164503
-
NADPH oxidase and erk1/2 are involved in cadmium induced-stat3 activation in hepg2 cells
-
Souza V, Escobar Mdel C, Bucio L, Hernandez E, Gomez-Quiroz LE, Gutierrez Ruiz MC. (2009). NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. Toxicol Lett 187: 180-186.
-
(2009)
Toxicol Lett
, vol.187
, pp. 180-186
-
-
Souza, V.1
Escobar Mdel, C.2
Bucio, L.3
Hernandez, E.4
Gomez-Quiroz, L.E.5
Gutierrez Ruiz, M.C.6
-
38
-
-
0037044820
-
Binding of C/EBP and RBP (CBF1) to overlapping sites regulates interleukin-6 gene expression
-
DOI 10.1074/jbc.M207363200
-
Vales LD, Friedl EM. (2002). Binding of C/EBP and RBP (CBF1) to overlapping sites regulates interleukin-6 gene expression. J Biol Chem 277: 42438-42446. (Pubitemid 35285609)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.45
, pp. 42438-42446
-
-
Vales, L.D.1
Friedl, E.M.2
-
39
-
-
67650898259
-
IRSS: A webbased tool for automatic layout and analysis of IRES secondary structure prediction and searching system in silico
-
Wu TY, Hsieh CC, Hong JJ, Chen CY, Tsai YS. (2009). IRSS: a webbased tool for automatic layout and analysis of IRES secondary structure prediction and searching system in silico. BMC Bioinform 10: 160.
-
(2009)
BMC Bioinform
, vol.10
, pp. 160
-
-
Wu, T.Y.1
Hsieh, C.C.2
Hong, J.J.3
Chen, C.Y.4
Tsai, Y.S.5
-
40
-
-
79959658547
-
Nf-kb and cancer: A paradigm of yin-yang
-
Xiao G, Fu J. (2011). NF-kB and cancer: a paradigm of Yin-Yang. Am J Cancer Res 1: 192-221.
-
(2011)
Am J Cancer Res
, vol.1
, pp. 192-221
-
-
Xiao, G.1
Fu, J.2
-
41
-
-
34249868449
-
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFκB
-
DOI 10.1101/gad.1553707
-
Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR. (2007). Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NF kappa B. Genes Dev 21: 1396-1408. (Pubitemid 46871042)
-
(2007)
Genes and Development
, vol.21
, Issue.11
, pp. 1396-1408
-
-
Yang, J.1
Liao, X.2
Agarwal, M.K.3
Barnes, L.4
Auron, P.E.5
Stark, G.R.6
-
42
-
-
72449211941
-
Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without cdkn2a mutations
-
Yang XR, Pfeiffer RM, Wheeler W, Yeager M, Chanock S, Tucker MA et al. (2009). Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. Int J Cancer 125: 2912-2917.
-
(2009)
Int J Cancer
, vol.125
, pp. 2912-2917
-
-
Yang, X.R.1
Pfeiffer, R.M.2
Wheeler, W.3
Yeager, M.4
Chanock, S.5
Tucker, M.A.6
-
43
-
-
0029740336
-
The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: Inhibition of AP1 binding and activation of a silencer element
-
Ye J, Cippitelli M, Dorman L, Ortaldo JR, Young HA. (1996). The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: inhibition of AP1 binding and activation of a silencer element. Mol Cell Biol 16: 4744-4753. (Pubitemid 26272128)
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.9
, pp. 4744-4753
-
-
Ye, J.1
Cippitelli, M.2
Dorman, L.3
Ortaldo, J.R.4
Young, H.A.5
-
44
-
-
77953565102
-
The gcn2-atf4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
-
Ye J, Kumanova M, Hart LS, Sloane K, Zhang H, De Panis DN et al. (2010). The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. EMBO J 29: 2082-2096.
-
(2010)
EMBO J
, vol.29
, pp. 2082-2096
-
-
Ye, J.1
Kumanova, M.2
Hart, L.S.3
Sloane, K.4
Zhang, H.5
De Panis, D.N.6
-
45
-
-
78649251953
-
Stat3 transcriptional factor activated by reactive oxygen species induces il6 in starvation-induced autophagy of cancer cells
-
Yoon S, Woo SU, Kang JH, Kim K, Kwon MH, Park S et al. (2010). STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells. Autophagy 6: 1125-1138.
-
(2010)
Autophagy
, vol.6
, pp. 1125-1138
-
-
Yoon, S.1
Woo, S.U.2
Kang, J.H.3
Kim, K.4
Kwon, M.H.5
Park, S.6
-
46
-
-
1042302005
-
The stats of cancer - New molecular targets come of age
-
Yu H, Jove R. (2004). The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 4: 97-105. (Pubitemid 38198738)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.2
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
47
-
-
47949099916
-
From endoplasmic-reticulum stress to the inflammatory response
-
Zhang K, Kaufman RJ. (2008). From endoplasmic-reticulum stress to the inflammatory response. Nature 454: 455-462.
-
(2008)
Nature
, vol.454
, pp. 455-462
-
-
Zhang, K.1
Kaufman, R.J.2
|