메뉴 건너뛰기




Volumn 16, Issue 9, 1996, Pages 4744-4753

The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: Inhibition of AP1 binding and activation of a silencer element

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DNA; DNA BINDING PROTEIN; GAMMA INTERFERON; NUCLEAR FACTOR; RECOMBINANT PROTEIN;

EID: 0029740336     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.9.4744     Document Type: Article
Times cited : (158)

References (54)
  • 1
    • 0023355884 scopus 로고
    • 12-O-Tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region
    • Angel, P., I. Baumann, B. Stein, H. Delius, H. J. Rahmsdorf, and P. Herrlich. 1987. 12-O-Tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region. Mol. Cell. Biol. 7:2256-2266.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2256-2266
    • Angel, P.1    Baumann, I.2    Stein, B.3    Delius, H.4    Rahmsdorf, H.J.5    Herrlich, P.6
  • 2
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel, P., and M. Karin. 1991. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochem. Biophys. Acta 1072:129-157.
    • (1991) Biochem. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 3
    • 0027535524 scopus 로고
    • Identification of a transcriptional initiator element in the cytochrome c oxidase subunit Vb promoter which binds to transcription factors NF-E1 (YY1, δ) and Sp1
    • Basu, A., K. Park, M. L. Atchison, R. S. Carter, and N. G. Avadhani. 1993. Identification of a transcriptional initiator element in the cytochrome c oxidase subunit Vb promoter which binds to transcription factors NF-E1 (YY1, δ) and Sp1. J. Biol. Chem. 268:4188-4196.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4188-4196
    • Basu, A.1    Park, K.2    Atchison, M.L.3    Carter, R.S.4    Avadhani, N.G.5
  • 4
    • 0026440998 scopus 로고
    • Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: Interaction with the transcriptional repressor YY1
    • Bauknecht, T., P. Angel, H-D. Royer, and H. Z. Hausen. 1992. Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1. EMBO J. 11: 4607-4617.
    • (1992) EMBO J. , vol.11 , pp. 4607-4617
    • Bauknecht, T.1    Angel, P.2    Royer, H.-D.3    Hausen, H.Z.4
  • 5
    • 0025072964 scopus 로고
    • A model of human cytokine regulation based on transfection of γ interferon gene fragments directly into isolated peripheral blood T lymphocytes
    • Chrivia, J. C., T. Wedrychowicz, H. A. Young, and K. J. Hardy. 1990. A model of human cytokine regulation based on transfection of γ interferon gene fragments directly into isolated peripheral blood T lymphocytes. J. Exp. Med. 172:661-664.
    • (1990) J. Exp. Med. , vol.172 , pp. 661-664
    • Chrivia, J.C.1    Wedrychowicz, T.2    Young, H.A.3    Hardy, K.J.4
  • 6
    • 0025020621 scopus 로고
    • Identification of enhancer-like elements in human IFN-γ genomic DNA
    • Ciccarone, V. C., J. Chrivia, K. J. Hardy, and H. A. Young. 1990. Identification of enhancer-like elements in human IFN-γ genomic DNA. J. Immunol. 144:735-730.
    • (1990) J. Immunol. , vol.144 , pp. 735-1730
    • Ciccarone, V.C.1    Chrivia, J.2    Hardy, K.J.3    Young, H.A.4
  • 7
    • 0029052324 scopus 로고
    • Negative transcriptional regulation of the interferon-γ promoter by glucocorticoid and dominant negative mutants of c-Jun
    • Cippitelli, M., A. Sica, V. Viggiano, J. Ye, P. Ghosh, M. J. Birrer, and H. A. Young. 1995. Negative transcriptional regulation of the interferon-γ promoter by glucocorticoid and dominant negative mutants of c-Jun. J. Biol. Chem. 270:12548-12556.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12548-12556
    • Cippitelli, M.1    Sica, A.2    Viggiano, V.3    Ye, J.4    Ghosh, P.5    Birrer, M.J.6    Young, H.A.7
  • 8
    • 0028079661 scopus 로고
    • Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells
    • Dong, Z., M. J. Birrer, R. G. Watts, L. M. Matrisian, and N. H. Colburn. 1994. Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc. Natl. Acad. Sci. USA 91:609-613.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 609-613
    • Dong, Z.1    Birrer, M.J.2    Watts, R.G.3    Matrisian, L.M.4    Colburn, N.H.5
  • 10
    • 0028318464 scopus 로고
    • Identification and characterization of a novel repressor site in the human tumor necrosis factor α gene
    • Fong, C.-L. W., A. H. Siddiqui, and D. F. Mark. 1994. Identification and characterization of a novel repressor site in the human tumor necrosis factor α gene. Nucleic Acids Res. 22:1108-1114.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1108-1114
    • Fong, C.-L.W.1    Siddiqui, A.H.2    Mark, D.F.3
  • 11
    • 0022523095 scopus 로고
    • The human β-interferon gene enhancer is under negative control
    • Goodbourn, S., H. Burstein, and T. Maniatis. 1986. The human β-interferon gene enhancer is under negative control. Cell 45:601-610.
    • (1986) Cell , vol.45 , pp. 601-610
    • Goodbourn, S.1    Burstein, H.2    Maniatis, T.3
  • 12
    • 0027486297 scopus 로고
    • Molecular regulation of the human IL-3 gene: Inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites
    • Gottschalk, L. R., D. M. Giannola, and S. G. Emerson. 1993. Molecular regulation of the human IL-3 gene: inducible T cell-restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites. J. Exp. Med. 178:1681-1692.
    • (1993) J. Exp. Med. , vol.178 , pp. 1681-1692
    • Gottschalk, L.R.1    Giannola, D.M.2    Emerson, S.G.3
  • 14
    • 0001187488 scopus 로고
    • The yin and the yang of mammalian transcription
    • Hahn, S. 1992. The yin and the yang of mammalian transcription. Curr. Biol. 2:152-154.
    • (1992) Curr. Biol. , vol.2 , pp. 152-154
    • Hahn, S.1
  • 15
    • 0023771685 scopus 로고
    • c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities
    • Halazonetis, T. D., K. Georgopoulos, M. E. Greenberg, and P. Leder. 1988. c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell 55:917-924.
    • (1988) Cell , vol.55 , pp. 917-924
    • Halazonetis, T.D.1    Georgopoulos, K.2    Greenberg, M.E.3    Leder, P.4
  • 16
    • 0026008651 scopus 로고
    • δ, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein
    • Hariharan, N., D. E. Kelley, and R. P. Perry. 1991. δ, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein. Proc. Natl. Acad. Sci. USA 88: 9799-9803.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9799-9803
    • Hariharan, N.1    Kelley, D.E.2    Perry, R.P.3
  • 17
    • 0023663116 scopus 로고
    • Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP
    • Imagawa, M., R. Chiu, and M. Karin. 1987. Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP. Cell 51:251-260.
    • (1987) Cell , vol.51 , pp. 251-260
    • Imagawa, M.1    Chiu, R.2    Karin, M.3
  • 18
    • 0028335152 scopus 로고
    • Relief of YY1-induced transcriptional repression by protein-protein interaction with the nuclear phosphoprotein B23
    • Inouye, C. J., and E. Seto. 1994. Relief of YY1-induced transcriptional repression by protein-protein interaction with the nuclear phosphoprotein B23. J. Biol. Chem. 269:6506-6510.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6506-6510
    • Inouye, C.J.1    Seto, E.2
  • 19
    • 0023665120 scopus 로고
    • Reversible silencing of enhancer by sequences derived from the human IFN-α promoter
    • Kuhl, D., J. D. L. Fuente, M. Chaturvedi, S. Parimoo, J. Ryals, F. Meyer, and C. Weissmann. 1987. Reversible silencing of enhancer by sequences derived from the human IFN-α promoter. Cell 50:1057-1069.
    • (1987) Cell , vol.50 , pp. 1057-1069
    • Kuhl, D.1    Fuente, J.D.L.2    Chaturvedi, M.3    Parimoo, S.4    Ryals, J.5    Meyer, F.6    Weissmann, C.7
  • 20
    • 0027241738 scopus 로고
    • Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1
    • Let, J.-S., K. M. Galvin, and Y. Shi. 1993. Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1. Proc. Natl. Acad. Sci. USA 90:6145-6149.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6145-6149
    • Let, J.-S.1    Galvin, K.M.2    Shi, Y.3
  • 22
    • 0026657069 scopus 로고
    • Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal α-actin transcription in embryonic myoblasts
    • Lee, T.-C., Y. Shi and J. Schwartz. 1992. Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal α-actin transcription in embryonic myoblasts. Proc. Natl. Acad. Sci. USA 89:9814-9818.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9814-9818
    • Lee, T.-C.1    Shi, Y.2    Schwartz, J.3
  • 23
    • 0026510627 scopus 로고
    • T cell-specific negative regulation of transcription of the human cytokine IL-4
    • Li-Weber, M., A. Eder, H. Krafft-Czepa, and P. H. Krammer. 1992. T cell-specific negative regulation of transcription of the human cytokine IL-4. J. Immunol. 148:1913-1918.
    • (1992) J. Immunol. , vol.148 , pp. 1913-1918
    • Li-Weber, M.1    Eder, A.2    Krafft-Czepa, H.3    Krammer, P.H.4
  • 24
    • 0028129088 scopus 로고
    • YY1 represses rat serum amyloid A1 gene transcription and is antagonized by NF-κB during acute-phase response
    • Lu, S.-Y., M. Rodriguez, and W. S.-L. Liao. 1994. YY1 represses rat serum amyloid A1 gene transcription and is antagonized by NF-κB during acute-phase response. Mol. Cell. Biol. 14:6253-6263.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6253-6263
    • Lu, S.-Y.1    Rodriguez, M.2    Liao, W.S.-L.3
  • 25
    • 0028120913 scopus 로고
    • Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production
    • Margolis, D. M., M. Somasundaran, and M. R. Green. 1994. Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production. J. Virol. 68:905-910.
    • (1994) J. Virol. , vol.68 , pp. 905-910
    • Margolis, D.M.1    Somasundaran, M.2    Green, M.R.3
  • 26
    • 0027488631 scopus 로고
    • The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT
    • Masuda, E. S., H. Tokumisu, A. Tsuboi, J. Shlomal, P. Hung, K.-I. Arai, and N. Arai. 1993. The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT. Mol. Cell. Biol. 13:7399-7407.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7399-7407
    • Masuda, E.S.1    Tokumisu, H.2    Tsuboi, A.3    Shlomal, J.4    Hung, P.5    Arai, K.-I.6    Arai, N.7
  • 28
    • 0028324821 scopus 로고
    • The E6/E7 promoter of extrachromosomal HPV16 DNA in cervical cancer escapes from cellular repression by mutation of target sequences for YY1
    • May, M., X.-P. Dong, E. Beyer-Finkler, F. Stubenrauch, P. G. Fuchs, and H. Pfister. 1994. The E6/E7 promoter of extrachromosomal HPV16 DNA in cervical cancer escapes from cellular repression by mutation of target sequences for YY1. EMBO J. 13:1460-1466.
    • (1994) EMBO J. , vol.13 , pp. 1460-1466
    • May, M.1    Dong, X.-P.2    Beyer-Finkler, E.3    Stubenrauch, F.4    Fuchs, P.G.5    Pfister, H.6
  • 29
    • 0028054824 scopus 로고
    • The nuclear factor YY1 participates in repression of the β-casein gene promoter in mammary epithelial cells and is counteracted by mammary gland factor during lactogenic hormone induction
    • Meier, V., and B. Groner. 1994. The nuclear factor YY1 participates in repression of the β-casein gene promoter in mammary epithelial cells and is counteracted by mammary gland factor during lactogenic hormone induction. Mol. Cell. Biol. 14:128-137.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 128-137
    • Meier, V.1    Groner, B.2
  • 30
    • 2642641167 scopus 로고
    • T-cell-specific expression of interleukin 2: Evidence for a negative regulatory site
    • Nabel, G. J., C. Gorka, and D. Baltimore. 1988. T-cell-specific expression of interleukin 2: evidence for a negative regulatory site. Proc. Natl. Acad. Sci. USA 85:2934-2938.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2934-2938
    • Nabel, G.J.1    Gorka, C.2    Baltimore, D.3
  • 31
    • 0027714828 scopus 로고
    • DNA bending and orientation-dependent function of YY1 in the c-fos promoter
    • Natesan, S., and M. Z. Gilman. 1993. DNA bending and orientation-dependent function of YY1 in the c-fos promoter. Genes Dev. 7:2497-2509.
    • (1993) Genes Dev. , vol.7 , pp. 2497-2509
    • Natesan, S.1    Gilman, M.Z.2
  • 32
    • 0028245317 scopus 로고
    • NF-AT-AP-1 and rel-bZIP: Hybrid vigor and binding under the influence
    • Nolan, G. P. 1994. NF-AT-AP-1 and rel-bZIP: hybrid vigor and binding under the influence. Cell 77:795-798.
    • (1994) Cell , vol.77 , pp. 795-798
    • Nolan, G.P.1
  • 33
    • 0027400136 scopus 로고
    • Interferon-β promoters contain a DNA element that acts as a position-independent silencer on the NF-κB site
    • Nourbakhsh, M., K. Hoffmann, and H. Hauser. 1993. Interferon-β promoters contain a DNA element that acts as a position-independent silencer on the NF-κB site. EMBO J. 12:451-459.
    • (1993) EMBO J. , vol.12 , pp. 451-459
    • Nourbakhsh, M.1    Hoffmann, K.2    Hauser, H.3
  • 34
    • 0027364319 scopus 로고
    • Two essential regulatory elements in the human interferon γ promoter confer activation-specific expression in T cells
    • Penix, L., W. M. Weaver, Y. Pang, H. A. Young, and C. B. Wilson. 1993. Two essential regulatory elements in the human interferon γ promoter confer activation-specific expression in T cells. J. Exp. Med. 178:1483-1496.
    • (1993) J. Exp. Med. , vol.178 , pp. 1483-1496
    • Penix, L.1    Weaver, W.M.2    Pang, Y.3    Young, H.A.4    Wilson, C.B.5
  • 35
    • 0028030884 scopus 로고
    • Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription
    • Petrak, D., S. A. Memon, M. J. Birrer, J. D. Ashwell, and C. M. Zacharchuk. 1994. Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription. J. Immunol. 153:2046-2051.
    • (1994) J. Immunol. , vol.153 , pp. 2046-2051
    • Petrak, D.1    Memon, S.A.2    Birrer, M.J.3    Ashwell, J.D.4    Zacharchuk, C.M.5
  • 36
    • 0028939923 scopus 로고
    • GATA1 and YY1 are developmental repressors of the human ε-globin gene
    • Raich, N., C. H. Clegg, J. Grofti, P.-H. Romeo, and G. Stamatoyannopoulos. 1995. GATA1 and YY1 are developmental repressors of the human ε-globin gene. EMBO J. 14:801-809.
    • (1995) EMBO J. , vol.14 , pp. 801-809
    • Raich, N.1    Clegg, C.H.2    Grofti, J.3    Romeo, P.-H.4    Stamatoyannopoulos, G.5
  • 37
    • 0028300431 scopus 로고
    • NF-ATp: A transcription factor required for the co-ordinate induction of several cytokine genes
    • Rao, A. 1994. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunol. Today 15:274-281.
    • (1994) Immunol. Today , vol.15 , pp. 274-281
    • Rao, A.1
  • 38
    • 0028173685 scopus 로고
    • YY1 represses β-casein gene expression by preventing the formation of a lactation-associated complex
    • Raught, B., B. Khursheed, A. Kazansky, and J. Rosen. 1994. YY1 represses β-casein gene expression by preventing the formation of a lactation-associated complex. Mol. Cell. Biol. 14:1752-1763.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1752-1763
    • Raught, B.1    Khursheed, B.2    Kazansky, A.3    Rosen, J.4
  • 40
    • 0027373948 scopus 로고
    • Interaction between transcription factors Sp1 and YY1
    • Seto, E., B. Lewis, and T. Shenk. 1993. Interaction between transcription factors Sp1 and YY1. Nature (London) 365:462-464.
    • (1993) Nature (London) , vol.365 , pp. 462-464
    • Seto, E.1    Lewis, B.2    Shenk, T.3
  • 41
    • 0026072263 scopus 로고
    • YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro
    • Seto, E., Y. Shi, and T. Shenk. 1991. YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro. Nature (London) 354:241-245.
    • (1991) Nature (London) , vol.354 , pp. 241-245
    • Seto, E.1    Shi, Y.2    Shenk, T.3
  • 42
    • 0025943945 scopus 로고
    • Transcriptional repression by YY1, a human GLI-Kruppel-rclated protein, and relief of repression by adenovirus E1A protein
    • Shi, Y., E. Seto, L.-S. Chang, and T. Shenk. 1991. Transcriptional repression by YY1, a human GLI-Kruppel-rclated protein, and relief of repression by adenovirus E1A protein. Cell 67:377-388.
    • (1991) Cell , vol.67 , pp. 377-388
    • Shi, Y.1    Seto, E.2    Chang, L.-S.3    Shenk, T.4
  • 43
    • 0028639172 scopus 로고
    • An analysis of genes regulated by the multifunctional transcription regulator Yin Yang-1
    • Shrivastava, A., and K. Calame. 1994. An analysis of genes regulated by the multifunctional transcription regulator Yin Yang-1. Nucleic Acids Res. 22: 5151-5155.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5151-5155
    • Shrivastava, A.1    Calame, K.2
  • 44
    • 0027745645 scopus 로고
    • Inhibition of transcription regulator Yin-Yang-1 by association with c-myc
    • Shrivastava, A., S. Saleque, G. V. Kalpana, S. Artandi, S. P. Goff, and K. Calame. 1993. Inhibition of transcription regulator Yin-Yang-1 by association with c-myc. Science 262:1889-1892.
    • (1993) Science , vol.262 , pp. 1889-1892
    • Shrivastava, A.1    Saleque, S.2    Kalpana, G.V.3    Artandi, S.4    Goff, S.P.5    Calame, K.6
  • 45
    • 0026601978 scopus 로고
    • The c-rel protooncogene product c-Rel but not NF-κB binds to the intronic region of the human interferon-γ gene at a site related to an interferon-stimulable response clement
    • Sica, A., T.-H. Tan, N. Rice, M. Kretzschmar, P. Ghosh, and H. A. Young. 1992. The c-rel protooncogene product c-Rel but not NF-κB binds to the intronic region of the human interferon-γ gene at a site related to an interferon-stimulable response clement. Proc. Natl. Acad. Sci. USA 89: 1740-1744.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1740-1744
    • Sica, A.1    Tan, T.-H.2    Rice, N.3    Kretzschmar, M.4    Ghosh, P.5    Young, H.A.6
  • 46
    • 0026665460 scopus 로고
    • κB site-dependent activation of the interleukin-2 receptor α-chain gene promoter by human c-Rel
    • Tan, T.-H., G. P. Huang, A. Sica, P. Ghosh, H. A. Young, D. L. Longo, and N. R. Rice. 1992. κB site-dependent activation of the interleukin-2 receptor α-chain gene promoter by human c-Rel. Mol. Cell. Biol. 12:4067-4075.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4067-4075
    • Tan, T.-H.1    Huang, G.P.2    Sica, A.3    Ghosh, P.4    Young, H.A.5    Longo, D.L.6    Rice, N.R.7
  • 47
    • 0028223852 scopus 로고
    • TATA-binding protein-independence initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA
    • Usheva, A., and T. Shenk. 1994. TATA-binding protein-independence initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA. Cell 76:1115-1121.
    • (1994) Cell , vol.76 , pp. 1115-1121
    • Usheva, A.1    Shenk, T.2
  • 50
    • 0029100898 scopus 로고
    • Cellular and molecular mechanisms of IFN-γ production induced by IL-2 and IL-12 in a human NK cell line
    • Ye, J., J. R. Ortaldo, K. Conlon, R. Winkler-Pickett, and H. A. Young. 1995. Cellular and molecular mechanisms of IFN-γ production induced by IL-2 and IL-12 in a human NK cell line. J. Leukocyte Biol. 58:225-233.
    • (1995) J. Leukocyte Biol. , vol.58 , pp. 225-233
    • Ye, J.1    Ortaldo, J.R.2    Conlon, K.3    Winkler-Pickett, R.4    Young, H.A.5
  • 51
    • 0028593994 scopus 로고
    • Identification of a DNA binding site for the nuclear factor YY1 in the human GM-CSF core promoter
    • Ye, J., H. A. Young, J. R. Ortaldo, and P. Ghosh. 1994. Identification of a DNA binding site for the nuclear factor YY1 in the human GM-CSF core promoter. Nucleic Acids Res. 22:5672-5678.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5672-5678
    • Ye, J.1    Young, H.A.2    Ortaldo, J.R.3    Ghosh, P.4
  • 53
    • 0025190966 scopus 로고
    • Interferon-γ: Producer cells, activation stimuli, and molecular genetic regulation
    • Young, H. A., and K. J. Hardy. 1989. Interferon-γ: producer cells, activation stimuli, and molecular genetic regulation. Pharmacol. Ther. 45:137-151.
    • (1989) Pharmacol. Ther. , vol.45 , pp. 137-151
    • Young, H.A.1    Hardy, K.J.2
  • 54
    • 0028068807 scopus 로고
    • Positive and negative regulation of IL-2 gene expression: Role of multiple regulatory sites
    • Zhang, L., and G. J. Nabel. 1994. Positive and negative regulation of IL-2 gene expression: role of multiple regulatory sites. Cytokine 6:221-228.
    • (1994) Cytokine , vol.6 , pp. 221-228
    • Zhang, L.1    Nabel, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.