Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3β and p53 in response to tumor necrosis factor α

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Vadrot, Nathalie ^a   Ghanem, Sarita ^a   Braut, Françoise ^a   Gavrilescu, Laura ^a   Pilard, Nathalie ^a   Mansouri, Abdellah ^a   Moreau, Richard ^a   Reyl Desmars, Florence ^a  

^a CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1;

APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CELL VIABILITY; CHEMOLUMINESCENCE; CONTROLLED STUDY; DNA CONTENT; ENZYME LINKED IMMUNOSORBENT ASSAY; EXCISION REPAIR; GENE DOSAGE; GENE SILENCING; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; MITOCHONDRIAL DNA DEPLETION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; WESTERN BLOTTING;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; DEOXYGUANOSINE; DNA DAMAGE; DNA REPAIR; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; GLYCOGEN SYNTHASE KINASE 3; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MITOCHONDRIAL PROTEINS; PROTEIN BINDING; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864104552     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040879     Document Type: Article

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