Cyclopentenyl cytosine induces senescence in breast cancer cells through the nucleolar stress response and activation of p53

Molecular Pharmacology

Volumn 80, Issue 1, 2011, Pages 40-48

  Huang, Min ^a,b   Whang, Patrick ^a,b   Lewicki, Patrick ^a,b   Mitchell, Beverly S ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4,5 DIHYDROXY 3 HYDROXYMETHYL 2 CYCLOPENTEN 1 YL)CYTOSINE; BETA GALACTOSIDASE; CYTIDINE TRIPHOSPHATE; CYTIDINE TRIPHOSPHATE SYNTHASE; NUCLEAR PROTEIN; NUCLEOLIN; NUCLEOSTEMIN; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL AGING; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL DEATH; CELL DIFFERENTIATION; CELL STRAIN MCF 7; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL AGING; CELL LINE, TUMOR; CELL NUCLEOLUS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTIDINE; CYTIDINE TRIPHOSPHATE; FEMALE; GENE SILENCING; GENES, P53; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; RNA, SMALL INTERFERING;

EID: 79959311537     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.110.070284     Document Type: Article

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