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Volumn 42, Issue 8, 2012, Pages 900-913

Regenerative pulmonary medicine: Potential and promise, pitfalls and challenges

Author keywords

Emphysema; Lung injury; Mesenchymal stem cell; Pulmonary hypertension; Regenerative medicine; Stem cell

Indexed keywords

CYTOKERATIN 5; HEME OXYGENASE 1; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P63; STEM CELL FACTOR RECEPTOR;

EID: 84863996373     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2012.02667.x     Document Type: Review
Times cited : (19)

References (134)
  • 1
    • 80051487211 scopus 로고    scopus 로고
    • Advancing respiratory research
    • Kiley JP. Advancing respiratory research. Chest 2011;140:497-501.
    • (2011) Chest , vol.140 , pp. 497-501
    • Kiley, J.P.1
  • 2
    • 80053316665 scopus 로고    scopus 로고
    • The registry of the international society for heart and lung transplantation: twenty-eighth adult lung and heart-lung transplant report - 2011
    • Christie JD, Edwards LB, Kucheryavaya AY, Benden C, Dobbels F, Kirk R et al. The registry of the international society for heart and lung transplantation: twenty-eighth adult lung and heart-lung transplant report - 2011. J Heart Lung Transplant 2011;30:1104-22.
    • (2011) J Heart Lung Transplant , vol.30 , pp. 1104-1122
    • Christie, J.D.1    Edwards, L.B.2    Kucheryavaya, A.Y.3    Benden, C.4    Dobbels, F.5    Kirk, R.6
  • 3
    • 80051491362 scopus 로고    scopus 로고
    • Bronchiolitis obliterans syndrome: the final frontier for lung transplantation
    • Todd JL, Palmer SM. Bronchiolitis obliterans syndrome: the final frontier for lung transplantation. Chest 2011;140:502-8.
    • (2011) Chest , vol.140 , pp. 502-508
    • Todd, J.L.1    Palmer, S.M.2
  • 4
    • 58449104363 scopus 로고    scopus 로고
    • Endogenous lung stem cells and contribution to disease
    • Snyder JC, Teisanu RM, Stripp BR. Endogenous lung stem cells and contribution to disease. J Pathol 2009;217:254-64.
    • (2009) J Pathol , vol.217 , pp. 254-264
    • Snyder, J.C.1    Teisanu, R.M.2    Stripp, B.R.3
  • 6
    • 80054030182 scopus 로고    scopus 로고
    • Epithelial progenitor cells in lung development, maintenance, repair, and disease
    • Rock JR, Hogan BL. Epithelial progenitor cells in lung development, maintenance, repair, and disease. Annu Rev Cell Dev Biol 2011;27:493-512.
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 493-512
    • Rock, J.R.1    Hogan, B.L.2
  • 7
    • 0018152081 scopus 로고
    • Role of the Clara cell in renewal of the bronchiolar epithelium
    • Evans MJ, Cabral-Anderson LJ, Freeman G. Role of the Clara cell in renewal of the bronchiolar epithelium. Lab Invest 1978;38:648-53.
    • (1978) Lab Invest , vol.38 , pp. 648-653
    • Evans, M.J.1    Cabral-Anderson, L.J.2    Freeman, G.3
  • 9
    • 0034974148 scopus 로고    scopus 로고
    • Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion
    • Hong KU, Reynolds SD, Giangreco A, Hurley CM, Stripp BR. Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. Am J Respir Cell Mol Biol 2001;24:671-81.
    • (2001) Am J Respir Cell Mol Biol , vol.24 , pp. 671-681
    • Hong, K.U.1    Reynolds, S.D.2    Giangreco, A.3    Hurley, C.M.4    Stripp, B.R.5
  • 10
    • 0036314791 scopus 로고    scopus 로고
    • Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
    • Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol 2002;161:173-82.
    • (2002) Am J Pathol , vol.161 , pp. 173-182
    • Giangreco, A.1    Reynolds, S.D.2    Stripp, B.R.3
  • 11
    • 1542319868 scopus 로고    scopus 로고
    • Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium
    • Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR. Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol 2004;164:577-88.
    • (2004) Am J Pathol , vol.164 , pp. 577-588
    • Hong, K.U.1    Reynolds, S.D.2    Watkins, S.3    Fuchs, E.4    Stripp, B.R.5
  • 12
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cancer
    • Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005;121:823-35.
    • (2005) Cell , vol.121 , pp. 823-835
    • Kim, C.F.1    Jackson, E.L.2    Woolfenden, A.E.3    Lawrence, S.4    Babar, I.5    Vogel, S.6
  • 13
    • 66049083441 scopus 로고    scopus 로고
    • The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium
    • Rawlins EL, Okubo T, Xue Y, Brass DM, Auten RL, Hasegawa H et al. The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell 2009;4:525-34.
    • (2009) Cell Stem Cell , vol.4 , pp. 525-534
    • Rawlins, E.L.1    Okubo, T.2    Xue, Y.3    Brass, D.M.4    Auten, R.L.5    Hasegawa, H.6
  • 16
    • 76549126430 scopus 로고    scopus 로고
    • Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung
    • McQualter JL, Yuen K, Williams B, Bertoncello I. Evidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lung. Proc Natl Acad Sci USA 2010;107:1414-9.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 1414-1419
    • McQualter, J.L.1    Yuen, K.2    Williams, B.3    Bertoncello, I.4
  • 17
    • 79952094467 scopus 로고    scopus 로고
    • Isolation of alveolar epithelial type II progenitor cells from adult human lungs
    • Fujino N, Kubo H, Suzuki T, Ota C, Hegab AE, He M et al. Isolation of alveolar epithelial type II progenitor cells from adult human lungs. Lab Invest 2011;91:363-78.
    • (2011) Lab Invest , vol.91 , pp. 363-378
    • Fujino, N.1    Kubo, H.2    Suzuki, T.3    Ota, C.4    Hegab, A.E.5    He, M.6
  • 18
    • 79959946669 scopus 로고    scopus 로고
    • Integrin alpha6beta4 identifies an adult distal lung epithelial population with regenerative potential in mice
    • Chapman HA, Li X, Alexander JP, Brumwell A, Lorizio W, Tan K et al. Integrin alpha6beta4 identifies an adult distal lung epithelial population with regenerative potential in mice. J Clin Invest 2011;121:2855-62.
    • (2011) J Clin Invest , vol.121 , pp. 2855-2862
    • Chapman, H.A.1    Li, X.2    Alexander, J.P.3    Brumwell, A.4    Lorizio, W.5    Tan, K.6
  • 19
    • 79960858341 scopus 로고    scopus 로고
    • Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential
    • Hegab AE, Ha VL, Gilbert JL, Zhang KX, Malkoski SP, Chon AT et al. Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential. Stem Cells 2011;29:1283-93.
    • (2011) Stem Cells , vol.29 , pp. 1283-1293
    • Hegab, A.E.1    Ha, V.L.2    Gilbert, J.L.3    Zhang, K.X.4    Malkoski, S.P.5    Chon, A.T.6
  • 20
    • 80155148257 scopus 로고    scopus 로고
    • Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection
    • Kumar PA, Hu Y, Yamamoto Y, Hoe NB, Wei TS, Mu D et al. Distal airway stem cells yield alveoli in vitro and during lung regeneration following H1N1 influenza infection. Cell 2011;147:525-38.
    • (2011) Cell , vol.147 , pp. 525-538
    • Kumar, P.A.1    Hu, Y.2    Yamamoto, Y.3    Hoe, N.B.4    Wei, T.S.5    Mu, D.6
  • 22
    • 79551586005 scopus 로고    scopus 로고
    • Therapeutic potential of lung epithelial progenitor cells derived from embryonic and induced pluripotent stem cells
    • Wetsel RA, Wang D, Calame DG. Therapeutic potential of lung epithelial progenitor cells derived from embryonic and induced pluripotent stem cells. Annu Rev Med 2011;62:95-105.
    • (2011) Annu Rev Med , vol.62 , pp. 95-105
    • Wetsel, R.A.1    Wang, D.2    Calame, D.G.3
  • 23
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981;292:154-6.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 25
    • 41349116799 scopus 로고    scopus 로고
    • Stem cells: 5 things to know before jumping on the iPS bandwagon
    • Cyranoski D. Stem cells: 5 things to know before jumping on the iPS bandwagon. Nature 2008;452:406-8.
    • (2008) Nature , vol.452 , pp. 406-408
    • Cyranoski, D.1
  • 26
    • 77955850887 scopus 로고    scopus 로고
    • Advances in reprogramming somatic cells to induced pluripotent stem cells
    • Patel M, Yang S. Advances in reprogramming somatic cells to induced pluripotent stem cells. Stem Cell Rev 2010;6:367-80.
    • (2010) Stem Cell Rev , vol.6 , pp. 367-380
    • Patel, M.1    Yang, S.2
  • 27
    • 77953159822 scopus 로고    scopus 로고
    • Human iPS cell-based therapy: considerations before clinical applications
    • Sun N, Longaker MT, Wu JC. Human iPS cell-based therapy: considerations before clinical applications. Cell Cycle 2010;9:880-5.
    • (2010) Cell Cycle , vol.9 , pp. 880-885
    • Sun, N.1    Longaker, M.T.2    Wu, J.C.3
  • 28
    • 70349815094 scopus 로고    scopus 로고
    • Tumors originating from induced pluripotent stem cells and methods for their prevention
    • Duinsbergen D, Salvatori D, Eriksson M, Mikkers H. Tumors originating from induced pluripotent stem cells and methods for their prevention. Ann N Y Acad Sci 2009;1176:197-204.
    • (2009) Ann N Y Acad Sci , vol.1176 , pp. 197-204
    • Duinsbergen, D.1    Salvatori, D.2    Eriksson, M.3    Mikkers, H.4
  • 30
    • 82255175382 scopus 로고    scopus 로고
    • Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial
    • Bolli R, Chugh AR, D'Amario D, Loughran JH, Stoddard MF, Ikram S et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 2011;378:1847-57.
    • (2011) Lancet , vol.378 , pp. 1847-1857
    • Bolli, R.1    Chugh, A.R.2    D'Amario, D.3    Loughran, J.H.4    Stoddard, M.F.5    Ikram, S.6
  • 31
    • 61749097005 scopus 로고    scopus 로고
    • Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium
    • Wong AP, Keating A, Lu WY, Duchesneau P, Wang X, Sacher A et al. Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium. J Clin Invest 2009;119:336-48.
    • (2009) J Clin Invest , vol.119 , pp. 336-348
    • Wong, A.P.1    Keating, A.2    Lu, W.Y.3    Duchesneau, P.4    Wang, X.5    Sacher, A.6
  • 33
    • 0016269155 scopus 로고
    • Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo
    • Friedenstein AJ, Chailakhyan RK, Latsinik NV, Panasyuk AF, Keiliss-Borok IV. Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation 1974;17:331-40.
    • (1974) Transplantation , vol.17 , pp. 331-340
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Latsinik, N.V.3    Panasyuk, A.F.4    Keiliss-Borok, I.V.5
  • 34
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 1997;276:71-4.
    • (1997) Science , vol.276 , pp. 71-74
    • Prockop, D.J.1
  • 37
    • 33745503987 scopus 로고    scopus 로고
    • Mesenchymal stem cells reside in virtually all post-natal organs and tissues
    • da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 2006;119:2204-13.
    • (2006) J Cell Sci , vol.119 , pp. 2204-2213
    • da Silva Meirelles, L.1    Chagastelles, P.C.2    Nardi, N.B.3
  • 38
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair - current views
    • Phinney DG, Prockop DJ. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair - current views. Stem Cells 2007;25:2896-902.
    • (2007) Stem Cells , vol.25 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 39
    • 79551564502 scopus 로고    scopus 로고
    • Cellular therapies for lung disease: a distant horizon
    • Moodley Y, Manuelpillai U, Weiss DJ. Cellular therapies for lung disease: a distant horizon. Respirology 2011;16:223-37.
    • (2011) Respirology , vol.16 , pp. 223-237
    • Moodley, Y.1    Manuelpillai, U.2    Weiss, D.J.3
  • 41
    • 79960223740 scopus 로고    scopus 로고
    • Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease
    • Lai RC, Chen TS, Lim SK. Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease. Regen Med 2011;6:481-92.
    • (2011) Regen Med , vol.6 , pp. 481-492
    • Lai, R.C.1    Chen, T.S.2    Lim, S.K.3
  • 42
    • 79960408013 scopus 로고    scopus 로고
    • Bone marrow-derived stem cells and respiratory disease
    • Jones CP, Rankin SM. Bone marrow-derived stem cells and respiratory disease. Chest 2011;140:205-11.
    • (2011) Chest , vol.140 , pp. 205-211
    • Jones, C.P.1    Rankin, S.M.2
  • 44
    • 0345306119 scopus 로고    scopus 로고
    • Diverse origin and function of cells with endothelial phenotype obtained from adult human blood
    • Gulati R, Jevremovic D, Peterson TE, Chatterjee S, Shah V, Vile RG et al. Diverse origin and function of cells with endothelial phenotype obtained from adult human blood. Circ Res 2003;93:1023-5.
    • (2003) Circ Res , vol.93 , pp. 1023-1025
    • Gulati, R.1    Jevremovic, D.2    Peterson, T.E.3    Chatterjee, S.4    Shah, V.5    Vile, R.G.6
  • 45
    • 67749108267 scopus 로고    scopus 로고
    • Endothelial progenitor cell: ongoing controversy for defining these cells and their role in neoangiogenesis in the murine system
    • Yoder MC, Ingram DA. Endothelial progenitor cell: ongoing controversy for defining these cells and their role in neoangiogenesis in the murine system. Curr Opin Hematol 2009;16:269-73.
    • (2009) Curr Opin Hematol , vol.16 , pp. 269-273
    • Yoder, M.C.1    Ingram, D.A.2
  • 46
    • 49449093753 scopus 로고    scopus 로고
    • Engineering of a complex organ: progress toward development of a tissue-engineered lung
    • Nichols JE, Cortiella J. Engineering of a complex organ: progress toward development of a tissue-engineered lung. Proc Am Thorac Soc 2008;5:723-30.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 723-730
    • Nichols, J.E.1    Cortiella, J.2
  • 48
    • 33745798223 scopus 로고    scopus 로고
    • Tissue-engineered lung: an in vivo and in vitro comparison of polyglycolic acid and pluronic F-127 hydrogel/somatic lung progenitor cell constructs to support tissue growth
    • Cortiella J, Nichols JE, Kojima K, Bonassar LJ, Dargon P, Roy AK et al. Tissue-engineered lung: an in vivo and in vitro comparison of polyglycolic acid and pluronic F-127 hydrogel/somatic lung progenitor cell constructs to support tissue growth. Tissue Eng 2006;12:1213-25.
    • (2006) Tissue Eng , vol.12 , pp. 1213-1225
    • Cortiella, J.1    Nichols, J.E.2    Kojima, K.3    Bonassar, L.J.4    Dargon, P.5    Roy, A.K.6
  • 51
    • 14844360656 scopus 로고    scopus 로고
    • Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease
    • Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, Stewart DJ. Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease. Circ Res 2005;96:442-50.
    • (2005) Circ Res , vol.96 , pp. 442-450
    • Zhao, Y.D.1    Courtman, D.W.2    Deng, Y.3    Kugathasan, L.4    Zhang, Q.5    Stewart, D.J.6
  • 52
    • 80655125159 scopus 로고    scopus 로고
    • Cell-based therapies for lung vascular diseases: lessons for the future
    • Stewart DJ, Mei SH. Cell-based therapies for lung vascular diseases: lessons for the future. Proc Am Thorac Soc 2011;8:535-40.
    • (2011) Proc Am Thorac Soc , vol.8 , pp. 535-540
    • Stewart, D.J.1    Mei, S.H.2
  • 53
    • 34047108549 scopus 로고    scopus 로고
    • Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: a pilot randomized controlled trial
    • Wang XX, Zhang FR, Shang YP, Zhu JH, Xie XD, Tao QM et al. Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: a pilot randomized controlled trial. J Am Coll Cardiol 2007;49:1566-71.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1566-1571
    • Wang, X.X.1    Zhang, F.R.2    Shang, Y.P.3    Zhu, J.H.4    Xie, X.D.5    Tao, Q.M.6
  • 54
    • 49349116828 scopus 로고    scopus 로고
    • Safety and efficacy of autologous endothelial progenitor cells transplantation in children with idiopathic pulmonary arterial hypertension: open-label pilot study
    • Zhu JH, Wang XX, Zhang FR, Shang YP, Tao QM, Chen JZ. Safety and efficacy of autologous endothelial progenitor cells transplantation in children with idiopathic pulmonary arterial hypertension: open-label pilot study. Pediatr Transplant 2008;12:650-5.
    • (2008) Pediatr Transplant , vol.12 , pp. 650-655
    • Zhu, J.H.1    Wang, X.X.2    Zhang, F.R.3    Shang, Y.P.4    Tao, Q.M.5    Chen, J.Z.6
  • 56
    • 0017119380 scopus 로고
    • Fibroblast precursors in normal and irradiated mouse hematopoietic organs
    • Friedenstein AJ, Gorskaja JF, Kulagina NN. Fibroblast precursors in normal and irradiated mouse hematopoietic organs. Exp Hematol 1976;4:267-74.
    • (1976) Exp Hematol , vol.4 , pp. 267-274
    • Friedenstein, A.J.1    Gorskaja, J.F.2    Kulagina, N.N.3
  • 58
    • 0033694301 scopus 로고    scopus 로고
    • Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    • Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-34.
    • (2000) Nat Med , vol.6 , pp. 1229-1234
    • Lagasse, E.1    Connors, H.2    Al-Dhalimy, M.3    Reitsma, M.4    Dohse, M.5    Osborne, L.6
  • 59
    • 0035805055 scopus 로고    scopus 로고
    • Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
    • Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-77.
    • (2001) Cell , vol.105 , pp. 369-377
    • Krause, D.S.1    Theise, N.D.2    Collector, M.I.3    Henegariu, O.4    Hwang, S.5    Gardner, R.6
  • 60
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006;8:315-7.
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3    Slaper-Cortenbach, I.4    Marini, F.5    Krause, D.6
  • 62
    • 1442356953 scopus 로고    scopus 로고
    • Isolation of multipotent mesenchymal stem cells from umbilical cord blood
    • Lee OK, Kuo TK, Chen WM, Lee KD, Hsieh SL, Chen TH. Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood 2004;103:1669-75.
    • (2004) Blood , vol.103 , pp. 1669-1675
    • Lee, O.K.1    Kuo, T.K.2    Chen, W.M.3    Lee, K.D.4    Hsieh, S.L.5    Chen, T.H.6
  • 63
    • 3543003475 scopus 로고    scopus 로고
    • Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood
    • Bieback K, Kern S, Kluter H, Eichler H. Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood. Stem Cells 2004;22:625-34.
    • (2004) Stem Cells , vol.22 , pp. 625-634
    • Bieback, K.1    Kern, S.2    Kluter, H.3    Eichler, H.4
  • 64
    • 10444248938 scopus 로고    scopus 로고
    • Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord
    • Wang HS, Hung SC, Peng ST, Huang CC, Wei HM, Guo YJ et al. Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 2004;22:1330-7.
    • (2004) Stem Cells , vol.22 , pp. 1330-1337
    • Wang, H.S.1    Hung, S.C.2    Peng, S.T.3    Huang, C.C.4    Wei, H.M.5    Guo, Y.J.6
  • 65
    • 33750559121 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease
    • Yanez R, Lamana ML, Garcia-Castro J, Colmenero I, Ramirez M, Bueren JA. Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells 2006;24:2582-91.
    • (2006) Stem Cells , vol.24 , pp. 2582-2591
    • Yanez, R.1    Lamana, M.L.2    Garcia-Castro, J.3    Colmenero, I.4    Ramirez, M.5    Bueren, J.A.6
  • 66
    • 40349110711 scopus 로고    scopus 로고
    • Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases
    • Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R et al. Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases. JAMA 2008;299:925-36.
    • (2008) JAMA , vol.299 , pp. 925-936
    • Burt, R.K.1    Loh, Y.2    Pearce, W.3    Beohar, N.4    Barr, W.G.5    Craig, R.6
  • 67
    • 34047156273 scopus 로고    scopus 로고
    • Stem cells and chronic lung disease
    • Gomperts BN, Strieter RM. Stem cells and chronic lung disease. Annu Rev Med 2007;58:285-98.
    • (2007) Annu Rev Med , vol.58 , pp. 285-298
    • Gomperts, B.N.1    Strieter, R.M.2
  • 68
    • 33646687955 scopus 로고    scopus 로고
    • Adult bone marrow-derived stem cells for the lung: implications for pediatric lung diseases
    • van Haaften T, Thebaud B. Adult bone marrow-derived stem cells for the lung: implications for pediatric lung diseases. Pediatr Res 2006;59:94R-9R.
    • (2006) Pediatr Res , vol.59
    • van Haaften, T.1    Thebaud, B.2
  • 72
    • 34147131808 scopus 로고    scopus 로고
    • Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts
    • Lama VN, Smith L, Badri L, Flint A, Andrei AC, Murray S et al. Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts. J Clin Invest 2007;117:989-96.
    • (2007) J Clin Invest , vol.117 , pp. 989-996
    • Lama, V.N.1    Smith, L.2    Badri, L.3    Flint, A.4    Andrei, A.C.5    Murray, S.6
  • 74
    • 72049118713 scopus 로고    scopus 로고
    • Human umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats
    • Chang YS, Oh W, Choi SJ, Sung DK, Kim SY, Choi EY et al. Human umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats. Cell Transplant 2009;18:869-86.
    • (2009) Cell Transplant , vol.18 , pp. 869-886
    • Chang, Y.S.1    Oh, W.2    Choi, S.J.3    Sung, D.K.4    Kim, S.Y.5    Choi, E.Y.6
  • 76
    • 0036841473 scopus 로고    scopus 로고
    • Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow
    • Theise ND, Henegariu O, Grove J, Jagirdar J, Kao PN, Crawford JM et al. Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow. Exp Hematol 2002;30:1333-8.
    • (2002) Exp Hematol , vol.30 , pp. 1333-1338
    • Theise, N.D.1    Henegariu, O.2    Grove, J.3    Jagirdar, J.4    Kao, P.N.5    Crawford, J.M.6
  • 77
    • 0348230711 scopus 로고    scopus 로고
    • Transplanted BM and BM side population cells contribute progeny to the lung and liver in irradiated mice
    • Abe S, Lauby G, Boyer C, Rennard SI, Sharp JG. Transplanted BM and BM side population cells contribute progeny to the lung and liver in irradiated mice. Cytotherapy 2003;5:523-33.
    • (2003) Cytotherapy , vol.5 , pp. 523-533
    • Abe, S.1    Lauby, G.2    Boyer, C.3    Rennard, S.I.4    Sharp, J.G.5
  • 78
    • 0036961904 scopus 로고    scopus 로고
    • SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats
    • Hatch HM, Zheng D, Jorgensen ML, Petersen BE. SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. Cloning Stem Cells 2002;4:339-51.
    • (2002) Cloning Stem Cells , vol.4 , pp. 339-351
    • Hatch, H.M.1    Zheng, D.2    Jorgensen, M.L.3    Petersen, B.E.4
  • 79
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • Wagers AJ, Sherwood RI, Christensen JL, Weissman IL. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 2002;297:2256-9.
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 81
    • 0242495039 scopus 로고    scopus 로고
    • Plasticity of marrow-derived stem cells
    • Herzog EL, Chai L, Krause DS. Plasticity of marrow-derived stem cells. Blood 2003;102:3483-93.
    • (2003) Blood , vol.102 , pp. 3483-3493
    • Herzog, E.L.1    Chai, L.2    Krause, D.S.3
  • 83
    • 23044455018 scopus 로고    scopus 로고
    • Bone marrow-derived stem-cell repopulation contributes minimally to the Type II pneumocyte pool in transplanted human lungs
    • Zander DS, Baz MA, Cogle CR, Visner GA, Theise ND, Crawford JM. Bone marrow-derived stem-cell repopulation contributes minimally to the Type II pneumocyte pool in transplanted human lungs. Transplantation 2005;80:206-12.
    • (2005) Transplantation , vol.80 , pp. 206-212
    • Zander, D.S.1    Baz, M.A.2    Cogle, C.R.3    Visner, G.A.4    Theise, N.D.5    Crawford, J.M.6
  • 84
    • 1642454668 scopus 로고    scopus 로고
    • Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury
    • Yamada M, Kubo H, Kobayashi S, Ishizawa K, Numasaki M, Ueda S et al. Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury. J Immunol 2004;172:1266-72.
    • (2004) J Immunol , vol.172 , pp. 1266-1272
    • Yamada, M.1    Kubo, H.2    Kobayashi, S.3    Ishizawa, K.4    Numasaki, M.5    Ueda, S.6
  • 85
    • 34548610480 scopus 로고    scopus 로고
    • Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    • Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007;179:1855-63.
    • (2007) J Immunol , vol.179 , pp. 1855-1863
    • Gupta, N.1    Su, X.2    Popov, B.3    Lee, J.W.4    Serikov, V.5    Matthay, M.A.6
  • 86
    • 34848853276 scopus 로고    scopus 로고
    • Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1
    • Mei SH, McCarter SD, Deng Y, Parker CH, Liles WC, Stewart DJ. Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med 2007;4:e269.
    • (2007) PLoS Med , vol.4
    • Mei, S.H.1    McCarter, S.D.2    Deng, Y.3    Parker, C.H.4    Liles, W.C.5    Stewart, D.J.6
  • 87
    • 0037478581 scopus 로고    scopus 로고
    • Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
    • Ortiz LA, Gambelli F, McBride C, Gaupp D, Baddoo M, Kaminski N et al. Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Natl Acad Sci USA 2003;100:8407-11.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8407-8411
    • Ortiz, L.A.1    Gambelli, F.2    McBride, C.3    Gaupp, D.4    Baddoo, M.5    Kaminski, N.6
  • 89
    • 33749993448 scopus 로고    scopus 로고
    • Autologous transplantation of adipose tissue-derived stromal cells ameliorates pulmonary emphysema
    • Shigemura N, Okumura M, Mizuno S, Imanishi Y, Nakamura T, Sawa Y. Autologous transplantation of adipose tissue-derived stromal cells ameliorates pulmonary emphysema. Am J Transplant 2006;6:2592-600.
    • (2006) Am J Transplant , vol.6 , pp. 2592-2600
    • Shigemura, N.1    Okumura, M.2    Mizuno, S.3    Imanishi, Y.4    Nakamura, T.5    Sawa, Y.6
  • 90
    • 42649127352 scopus 로고    scopus 로고
    • Mesenchymal stem cells transplantation protects against rat pulmonary emphysema
    • Zhen G, Liu H, Gu N, Zhang H, Xu Y, Zhang Z. Mesenchymal stem cells transplantation protects against rat pulmonary emphysema. Front Biosci 2008;13:3415-22.
    • (2008) Front Biosci , vol.13 , pp. 3415-3422
    • Zhen, G.1    Liu, H.2    Gu, N.3    Zhang, H.4    Xu, Y.5    Zhang, Z.6
  • 91
    • 78650923962 scopus 로고    scopus 로고
    • Paracrine factors of multipotent stromal cells ameliorate lung injury in an elastase-induced emphysema model
    • Katsha AM, Ohkouchi S, Xin H, Kanehira M, Sun R, Nukiwa T et al. Paracrine factors of multipotent stromal cells ameliorate lung injury in an elastase-induced emphysema model. Mol Ther 2010;19:196-203.
    • (2010) Mol Ther , vol.19 , pp. 196-203
    • Katsha, A.M.1    Ohkouchi, S.2    Xin, H.3    Kanehira, M.4    Sun, R.5    Nukiwa, T.6
  • 92
    • 33846980821 scopus 로고    scopus 로고
    • Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction
    • Baber SR, Deng W, Master RG, Bunnell BA, Taylor BK, Murthy SN et al. Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction. Am J Physiol Heart Circ Physiol 2007;292:H1120-8.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Baber, S.R.1    Deng, W.2    Master, R.G.3    Bunnell, B.A.4    Taylor, B.K.5    Murthy, S.N.6
  • 93
    • 33747186449 scopus 로고    scopus 로고
    • Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension
    • Kanki-Horimoto S, Horimoto H, Mieno S, Kishida K, Watanabe F, Furuya E et al. Implantation of mesenchymal stem cells overexpressing endothelial nitric oxide synthase improves right ventricular impairments caused by pulmonary hypertension. Circulation 2006;114:I181-5.
    • (2006) Circulation , vol.114
    • Kanki-Horimoto, S.1    Horimoto, H.2    Mieno, S.3    Kishida, K.4    Watanabe, F.5    Furuya, E.6
  • 94
    • 77952771680 scopus 로고    scopus 로고
    • Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats
    • Takemiya K, Kai H, Yasukawa H, Tahara N, Kato S, Imaizumi T. Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats. Basic Res Cardiol 2010;105:409-17.
    • (2010) Basic Res Cardiol , vol.105 , pp. 409-417
    • Takemiya, K.1    Kai, H.2    Yasukawa, H.3    Tahara, N.4    Kato, S.5    Imaizumi, T.6
  • 95
    • 0033561224 scopus 로고    scopus 로고
    • Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice
    • Yet SF, Perrella MA, Layne MD, Hsieh CM, Maemura K, Kobzik L et al. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest 1999;103:R23-9.
    • (1999) J Clin Invest , vol.103
    • Yet, S.F.1    Perrella, M.A.2    Layne, M.D.3    Hsieh, C.M.4    Maemura, K.5    Kobzik, L.6
  • 97
    • 79951819303 scopus 로고    scopus 로고
    • Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension
    • Liang OD, Mitsialis SA, Chang MS, Vergadi E, Lee C, Aslam M et al. Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension. Stem Cells 2011;29:99-107.
    • (2011) Stem Cells , vol.29 , pp. 99-107
    • Liang, O.D.1    Mitsialis, S.A.2    Chang, M.S.3    Vergadi, E.4    Lee, C.5    Aslam, M.6
  • 98
    • 77954982590 scopus 로고    scopus 로고
    • Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury
    • Manning E, Pham S, Li S, Vazquez-Padron RI, Mathew J, Ruiz P et al. Interleukin-10 delivery via mesenchymal stem cells: a novel gene therapy approach to prevent lung ischemia-reperfusion injury. Hum Gene Ther 2010;21:713-27.
    • (2010) Hum Gene Ther , vol.21 , pp. 713-727
    • Manning, E.1    Pham, S.2    Li, S.3    Vazquez-Padron, R.I.4    Mathew, J.5    Ruiz, P.6
  • 99
    • 31944451977 scopus 로고    scopus 로고
    • Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells
    • Loi R, Beckett T, Goncz KK, Suratt BT, Weiss DJ. Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells. Am J Respir Crit Care Med 2006;173:171-9.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 171-179
    • Loi, R.1    Beckett, T.2    Goncz, K.K.3    Suratt, B.T.4    Weiss, D.J.5
  • 100
    • 19944427214 scopus 로고    scopus 로고
    • Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis
    • Wang G, Bunnell BA, Painter RG, Quiniones BC, Tom S, Lanson NA Jr et al. Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc Natl Acad Sci USA 2005;102:186-91.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 186-191
    • Wang, G.1    Bunnell, B.A.2    Painter, R.G.3    Quiniones, B.C.4    Tom, S.5    Lanson Jr., N.A.6
  • 102
    • 77952893038 scopus 로고    scopus 로고
    • Mesenchymal stem cells rescue cardiomyoblasts from cell death in an in vitro ischemia model via direct cell-to-cell connections
    • Cselenyak A, Pankotai E, Horvath EM, Kiss L, Lacza Z. Mesenchymal stem cells rescue cardiomyoblasts from cell death in an in vitro ischemia model via direct cell-to-cell connections. BMC Cell Biol 2010;11:29.
    • (2010) BMC Cell Biol , vol.11 , pp. 29
    • Cselenyak, A.1    Pankotai, E.2    Horvath, E.M.3    Kiss, L.4    Lacza, Z.5
  • 103
    • 34547402979 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
    • Ortiz LA, Dutreil M, Fattman C, Pandey AC, Torres G, Go K et al. Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc Natl Acad Sci USA 2007;104:11002-7.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11002-11007
    • Ortiz, L.A.1    Dutreil, M.2    Fattman, C.3    Pandey, A.C.4    Torres, G.5    Go, K.6
  • 105
    • 79957619269 scopus 로고    scopus 로고
    • Concise review: mesenchymal stem cells for acute lung injury: role of paracrine soluble factors
    • Lee JW, Fang X, Krasnodembskaya A, Howard JP, Matthay MA. Concise review: mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. Stem Cells 2011;29:913-9.
    • (2011) Stem Cells , vol.29 , pp. 913-919
    • Lee, J.W.1    Fang, X.2    Krasnodembskaya, A.3    Howard, J.P.4    Matthay, M.A.5
  • 106
    • 0021288953 scopus 로고
    • Fetal and postnatal development of the lung
    • Burri PH. Fetal and postnatal development of the lung. Annu Rev Physiol 1984;46:617-28.
    • (1984) Annu Rev Physiol , vol.46 , pp. 617-628
    • Burri, P.H.1
  • 107
    • 33745069841 scopus 로고    scopus 로고
    • Structural aspects of postnatal lung development - alveolar formation and growth
    • Burri PH. Structural aspects of postnatal lung development - alveolar formation and growth. Biol Neonate 2006;89:313-22.
    • (2006) Biol Neonate , vol.89 , pp. 313-322
    • Burri, P.H.1
  • 108
    • 0014879343 scopus 로고
    • Growth of the alveoli and pulmonary arteries in childhood
    • Davies G, Reid L. Growth of the alveoli and pulmonary arteries in childhood. Thorax 1970;25:669-81.
    • (1970) Thorax , vol.25 , pp. 669-681
    • Davies, G.1    Reid, L.2
  • 109
    • 13544249881 scopus 로고    scopus 로고
    • Developmental biology of the pulmonary circulation
    • Hislop A. Developmental biology of the pulmonary circulation. Paediatr Respir Rev 2005;6:35-43.
    • (2005) Paediatr Respir Rev , vol.6 , pp. 35-43
    • Hislop, A.1
  • 110
    • 33745956858 scopus 로고    scopus 로고
    • 4. Stem and progenitor cells in the formation of the pulmonary vasculature
    • Fisher KA, Summer RS. 4. Stem and progenitor cells in the formation of the pulmonary vasculature. Curr Top Dev Biol 2006;74:117-31.
    • (2006) Curr Top Dev Biol , vol.74 , pp. 117-131
    • Fisher, K.A.1    Summer, R.S.2
  • 111
    • 75749146169 scopus 로고    scopus 로고
    • Coexistence of quiescent and active adult stem cells in mammals
    • Li L, Clevers H. Coexistence of quiescent and active adult stem cells in mammals. Science 2010;327:542-5.
    • (2010) Science , vol.327 , pp. 542-545
    • Li, L.1    Clevers, H.2
  • 112
    • 70349871249 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute perspective: lung progenitor and stem cells - gaps in knowledge and future opportunities
    • Blaisdell CJ, Gail DB, Nabel EG. National Heart, Lung, and Blood Institute perspective: lung progenitor and stem cells - gaps in knowledge and future opportunities. Stem Cells 2009;27:2263-70.
    • (2009) Stem Cells , vol.27 , pp. 2263-2270
    • Blaisdell, C.J.1    Gail, D.B.2    Nabel, E.G.3
  • 113
    • 79957922264 scopus 로고    scopus 로고
    • The three R's of lung health and disease: repair, remodeling, and regeneration
    • Beers MF, Morrisey EE. The three R's of lung health and disease: repair, remodeling, and regeneration. J Clin Invest 2011;121:2065-73.
    • (2011) J Clin Invest , vol.121 , pp. 2065-2073
    • Beers, M.F.1    Morrisey, E.E.2
  • 114
    • 80052486592 scopus 로고    scopus 로고
    • Tissue-specific adult stem cells in the human lung
    • Anversa P, Kajstura J, Leri A, Loscalzo J. Tissue-specific adult stem cells in the human lung. Nat Med 2011;17:1038-9.
    • (2011) Nat Med , vol.17 , pp. 1038-1039
    • Anversa, P.1    Kajstura, J.2    Leri, A.3    Loscalzo, J.4
  • 115
    • 80054862249 scopus 로고    scopus 로고
    • Lung stem cells - from an evolving understanding to a paradigm shift?
    • Hayes M, Curley GF, Laffey JG. Lung stem cells - from an evolving understanding to a paradigm shift? Stem Cell Res Ther 2011;2:41.
    • (2011) Stem Cell Res Ther , vol.2 , pp. 41
    • Hayes, M.1    Curley, G.F.2    Laffey, J.G.3
  • 116
    • 78650963929 scopus 로고    scopus 로고
    • Dynamics between stem cells, niche, and progeny in the hair follicle
    • Hsu YC, Pasolli HA, Fuchs E. Dynamics between stem cells, niche, and progeny in the hair follicle. Cell 2011;144:92-105.
    • (2011) Cell , vol.144 , pp. 92-105
    • Hsu, Y.C.1    Pasolli, H.A.2    Fuchs, E.3
  • 117
    • 81355147381 scopus 로고    scopus 로고
    • The haematopoietic stem cell niche at a glance
    • Lo Celso C, Scadden DT. The haematopoietic stem cell niche at a glance. J Cell Sci 2011;124:3529-35.
    • (2011) J Cell Sci , vol.124 , pp. 3529-3535
    • Lo Celso, C.1    Scadden, D.T.2
  • 118
    • 49449085453 scopus 로고    scopus 로고
    • The glandular stem/progenitor cell niche in airway development and repair
    • Liu X, Engelhardt JF. The glandular stem/progenitor cell niche in airway development and repair. Proc Am Thorac Soc 2008;5:682-8.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 682-688
    • Liu, X.1    Engelhardt, J.F.2
  • 119
    • 49449112792 scopus 로고    scopus 로고
    • Hierarchical organization of lung progenitor cells: is there an adult lung tissue stem cell?
    • Stripp BR. Hierarchical organization of lung progenitor cells: is there an adult lung tissue stem cell? Proc Am Thorac Soc 2008;5:695-8.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 695-698
    • Stripp, B.R.1
  • 120
    • 69549090537 scopus 로고    scopus 로고
    • Multiple roles for Sox2 in the developing and adult mouse trachea
    • Que J, Luo X, Schwartz RJ, Hogan BL. Multiple roles for Sox2 in the developing and adult mouse trachea. Development 2009;136:1899-907.
    • (2009) Development , vol.136 , pp. 1899-1907
    • Que, J.1    Luo, X.2    Schwartz, R.J.3    Hogan, B.L.4
  • 122
    • 74049139927 scopus 로고    scopus 로고
    • Preparing for the first breath: genetic and cellular mechanisms in lung development
    • Morrisey EE, Hogan BL. Preparing for the first breath: genetic and cellular mechanisms in lung development. Dev Cell 2010;18:8-23.
    • (2010) Dev Cell , vol.18 , pp. 8-23
    • Morrisey, E.E.1    Hogan, B.L.2
  • 123
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999;398:714-8.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3    Kaghad, M.4    Walker, N.5    Bronson, R.T.6
  • 126
    • 34347379049 scopus 로고    scopus 로고
    • p63: revving up epithelial stem-cell potential
    • Blanpain C, Fuchs E. p63: revving up epithelial stem-cell potential. Nat Cell Biol 2007;9:731-3.
    • (2007) Nat Cell Biol , vol.9 , pp. 731-733
    • Blanpain, C.1    Fuchs, E.2
  • 127
    • 80155123730 scopus 로고    scopus 로고
    • A breath of fresh air in lung regeneration
    • Beronja S, Fuchs E. A breath of fresh air in lung regeneration. Cell 2011;147:485-7.
    • (2011) Cell , vol.147 , pp. 485-487
    • Beronja, S.1    Fuchs, E.2
  • 128
    • 70549107968 scopus 로고    scopus 로고
    • Clara cell: progenitor for the bronchiolar epithelium
    • Reynolds SD, Malkinson AM. Clara cell: progenitor for the bronchiolar epithelium. Int J Biochem Cell Biol 2010;42:1-4.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1-4
    • Reynolds, S.D.1    Malkinson, A.M.2
  • 129
    • 0033875885 scopus 로고    scopus 로고
    • Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration
    • Reynolds SD, Giangreco A, Power JH, Stripp BR. Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. Am J Pathol 2000;156:269-78.
    • (2000) Am J Pathol , vol.156 , pp. 269-278
    • Reynolds, S.D.1    Giangreco, A.2    Power, J.H.3    Stripp, B.R.4
  • 131
    • 80052289137 scopus 로고    scopus 로고
    • Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci
    • Zacharek SJ, Fillmore CM, Lau AN, Gludish DW, Chou A, Ho JW et al. Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci. Cell Stem Cell 2011;9:272-81.
    • (2011) Cell Stem Cell , vol.9 , pp. 272-281
    • Zacharek, S.J.1    Fillmore, C.M.2    Lau, A.N.3    Gludish, D.W.4    Chou, A.5    Ho, J.W.6
  • 132
    • 22144481028 scopus 로고    scopus 로고
    • Stem cells of the alveolar epithelium
    • Griffiths MJ, Bonnet D, Janes SM. Stem cells of the alveolar epithelium. Lancet 2005;366:249-60.
    • (2005) Lancet , vol.366 , pp. 249-260
    • Griffiths, M.J.1    Bonnet, D.2    Janes, S.M.3
  • 133
    • 34547699399 scopus 로고    scopus 로고
    • Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
    • Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD et al. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med 2007;13:970-4.
    • (2007) Nat Med , vol.13 , pp. 970-974
    • Hsieh, P.C.1    Segers, V.F.2    Davis, M.E.3    MacGillivray, C.4    Gannon, J.5    Molkentin, J.D.6
  • 134


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