메뉴 건너뛰기




Volumn 27, Issue 9, 2009, Pages 2263-2270

National heart, lung, and blood institute perspective: Lung progenitor and stem cells - Gaps in knowledge and future opportunities

Author keywords

Lung cell biology; Lung regeneration; Reprogramming

Indexed keywords

FIBROBLAST GROWTH FACTOR; NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; THYROID TRANSCRIPTION FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

EID: 70349871249     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.148     Document Type: Review
Times cited : (19)

References (54)
  • 1
    • 49449105336 scopus 로고    scopus 로고
    • Lung epithelial progenitor cells: Lessons from development
    • Rawlins EL. Lung epithelial progenitor cells: lessons from development. Proc Am Thorac Soc 2008;5:675-681.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 675-681
    • Rawlins, E.L.1
  • 2
    • 68549136903 scopus 로고    scopus 로고
    • Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair
    • Rawlins EL, Okubo T, Que J et al. Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair. Cold Spring Harb Symp Quant Biol 2008;73:291-295.
    • (2008) Cold Spring Harb Symp Quant Biol , vol.73 , pp. 291-295
    • Rawlins, E.L.1    Okubo, T.2    Que, J.3
  • 3
    • 42049084004 scopus 로고    scopus 로고
    • Maintenance and repair of the bronchiolar epithelium
    • Stripp BR, Reynolds SD. Maintenance and repair of the bronchiolar epithelium. Proc Am Thorac Soc 2008;5:328-333.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 328-333
    • Stripp, B.R.1    Reynolds, S.D.2
  • 4
    • 33646236153 scopus 로고    scopus 로고
    • Adult stem cells, lung biology, and lung disease: NHLBI/cystic fibrosis foundation workshop
    • Weiss DJ, Berberich MA, Borok Z et al. Adult stem cells, lung biology, and lung disease: NHLBI/cystic fibrosis foundation workshop. Proc Am Thorac Soc 2006;3:193-207.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 193-207
    • Weiss, D.J.1    Berberich, M.A.2    Borok, Z.3
  • 6
    • 0031026847 scopus 로고    scopus 로고
    • Stem cells of the respiratory epithelium and their in vitro cultivation
    • Emura M. Stem cells of the respiratory epithelium and their in vitro cultivation. In Vitro Cell Dev Biol Anim 1997;33:3-14. (Pubitemid 27075132)
    • (1997) In Vitro Cellular and Developmental Biology - Animal , vol.33 , Issue.1 , pp. 3-14
    • Emura, M.1
  • 7
    • 49449085453 scopus 로고    scopus 로고
    • The glandular stem/progenitor cell niche in airway development and repair
    • Liu X, Engelhardt JF. The glandular stem/progenitor cell niche in airway development and repair. Proc Am Thorac Soc 2008;5:682-688.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 682-688
    • Liu, X.1    Engelhardt, J.F.2
  • 8
    • 0033826997 scopus 로고    scopus 로고
    • Inhibition of angiogenesis decreases alveolarization in the developing rat lung
    • Jakkula M, Le Cras TD, Gebb S et al. Inhibition of angiogenesis decreases alveolarization in the developing rat lung. Am J Physiol Lung Cell Mol Physiol 2000;279:L600-L607.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Jakkula, M.1    Le Cras, T.D.2    Gebb, S.3
  • 9
    • 34248384848 scopus 로고    scopus 로고
    • Bronchopulmonary dysplasia: Where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease
    • DOI 10.1164/rccm.200611-1660PP
    • Thébaud B, Abman SH. Bronchopulmonary dysplasia: where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease. Am J Respir Crit Care Med 2007;175:978-985. (Pubitemid 46741748)
    • (2007) American Journal of Respiratory and Critical Care Medicine , vol.175 , Issue.10 , pp. 978-985
    • Thebaud, B.1    Abman, S.H.2
  • 10
    • 44849091512 scopus 로고    scopus 로고
    • The branching programme of mouse lung development
    • Metzger RJ, Klein OD, Martin GR et al. The branching programme of mouse lung development. Nature 2008;453:745-750.
    • (2008) Nature , vol.453 , pp. 745-750
    • Metzger, R.J.1    Klein, O.D.2    Martin, G.R.3
  • 11
    • 50849085475 scopus 로고    scopus 로고
    • Lung vascular cell heterogeneity: Endothelium, smooth muscle, and fibroblasts
    • Stevens T, Phan S, Frid MG et al. Lung vascular cell heterogeneity: endothelium, smooth muscle, and fibroblasts. Proc Am Thorac Soc 2008;5:783-791.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 783-791
    • Stevens, T.1    Phan, S.2    Frid, M.G.3
  • 12
    • 41549100928 scopus 로고    scopus 로고
    • Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium
    • Clark J, Alvarez DF, Alexeyev M et al. Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol 2008;294:L431-L439.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.294
    • Clark, J.1    Alvarez, D.F.2    Alexeyev, M.3
  • 13
    • 0032707150 scopus 로고    scopus 로고
    • Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia
    • Kimura S, Ward JM, Minoo P. Thyroid-specific enhancer-binding protein/thyroid transcription factor 1 is not required for the initial specification of the thyroid and lung primordia. Biochimie 1999;81:321-327.
    • (1999) Biochimie , vol.81 , pp. 321-327
    • Kimura, S.1    Ward, J.M.2    Minoo, P.3
  • 14
    • 0030057596 scopus 로고    scopus 로고
    • The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
    • Kimura S, Hara Y, Pineau T et al. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev 1996;10:60-69. (Pubitemid 26025299)
    • (1996) Genes and Development , vol.10 , Issue.1 , pp. 60-69
    • Kimura, S.1    Hara, Y.2    Pineau, T.3    Fernandez-Salguero, P.4    Fox, C.H.5    Ward, J.M.6    Gonzalez, F.J.7
  • 15
    • 13444310931 scopus 로고    scopus 로고
    • Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
    • DOI 10.1242/dev.01570
    • Serls AE, Doherty S, Parvatiyar P et al. Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development 2005;132:35-47. (Pubitemid 40207965)
    • (2005) Development , vol.132 , Issue.1 , pp. 35-47
    • Serls, A.E.1    Doherty, S.2    Parvatiyar, P.3    Wells, J.M.4    Deutsch, G.H.5
  • 16
    • 40349083964 scopus 로고    scopus 로고
    • FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia
    • DOI 10.1186/1471-213X-8-2
    • Nyeng P, Norgaard GA, Kobberup S et al. Fgf10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol 2008;8:2. (Pubitemid 351342672)
    • (2008) BMC Developmental Biology , vol.8 , pp. 2
    • Nyeng, P.1    Norgaard, G.A.2    Kobberup, S.3    Jensen, J.4
  • 17
    • 34347364738 scopus 로고    scopus 로고
    • Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development
    • Ramasamy SK, Mailleux AA, Gupte VV et al. Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol 2007;307:237-247.
    • (2007) Dev Biol , vol.307 , pp. 237-247
    • Ramasamy, S.K.1    Mailleux, A.A.2    Gupte, V.V.3
  • 18
    • 34548562240 scopus 로고    scopus 로고
    • Inhibition of Tgfβ signaling by endogenous retinoic acid is essential for primary lung bud induction
    • DOI 10.1242/dev.006221
    • Chen F, Desai TJ, Qian J et al. Inhibition of TGF β signaling by endogenous retinoic acid is essential for primary lung bud induction. Development 2007;134:2969-2979. (Pubitemid 47393407)
    • (2007) Development , vol.134 , Issue.16 , pp. 2969-2979
    • Chen, F.1    Desai, T.J.2    Qian, J.3    Niederreither, K.4    Lu, J.5    Cardoso, W.V.6
  • 19
    • 20444445954 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung
    • Shu W, Guttentag S, Wang Z et al. Wnt/β-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol 2005;283:226-239.
    • (2005) Dev Biol , vol.283 , pp. 226-239
    • Shu, W.1    Guttentag, S.2    Wang, Z.3
  • 20
    • 70349862613 scopus 로고    scopus 로고
    • β-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium
    • Zemke AC, Teisanu RM, Giangreco A et al. β-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium. Am J Respir Cell Mol Biol 2009.
    • (2009) Am J Respir Cell Mol Biol
    • Zemke, A.C.1    Teisanu, R.M.2    Giangreco, A.3
  • 22
    • 1642269178 scopus 로고    scopus 로고
    • In vivo differentiation potential of tracheal basal cells: Evidence for multipotent and unipotent subpopulations
    • Hong KU, Reynolds SD, Watkins S et al. In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. Am J Physiol Lung Cell Mol Physiol 2004;286:L643-L649.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286
    • Hong, K.U.1    Reynolds, S.D.2    Watkins, S.3
  • 24
    • 66049083441 scopus 로고    scopus 로고
    • + Clara cells in the long-term maintenance and repair of lung airway, but not alveolar epithelium
    • + Clara cells in the long-term maintenance and repair of lung airway, but not alveolar epithelium. Cell Stem Cell 2009;4:525-534.
    • (2009) Cell Stem Cell , vol.4 , pp. 525-534
    • Rawlins, E.L.1    Okubo, T.2    Xue, Y.3
  • 27
    • 55049093300 scopus 로고    scopus 로고
    • Characterization of side population cells from human airway epithelium
    • Hackett TL, Shaheen F, Johnson A et al. Characterization of side population cells from human airway epithelium. Stem Cells 2008;26:2576-2585.
    • (2008) Stem Cells , vol.26 , pp. 2576-2585
    • Hackett, T.L.1    Shaheen, F.2    Johnson, A.3
  • 30
    • 0034974148 scopus 로고    scopus 로고
    • Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion
    • Hong KU, Reynolds SD, Giangreco A et al. Clara cell secretory protein- expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. Am J Respir Cell Mol Biol 2001;24:671-681. (Pubitemid 32550588)
    • (2001) American Journal of Respiratory Cell and Molecular Biology , vol.24 , Issue.6 , pp. 671-681
    • Hong, K.U.1    Reynolds, S.D.2    Giangreco, A.3    Hurley, C.M.4    Stripp, B.R.5
  • 31
    • 47949120382 scopus 로고    scopus 로고
    • Conditional stabilization of β-catenin expands the pool of lung stem cells
    • Reynolds SD, Zemke AC, Giangreco A et al. Conditional stabilization of β-catenin expands the pool of lung stem cells. Stem Cells 2008;26:1337-1346.
    • (2008) Stem Cells , vol.26 , pp. 1337-1346
    • Reynolds, S.D.1    Zemke, A.C.2    Giangreco, A.3
  • 32
    • 55949133275 scopus 로고    scopus 로고
    • Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development
    • Que J, Wilm B, Hasegawa H et al. Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. Proc Natl Acad Sci USA 2008;105:16626-16630.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16626-16630
    • Que, J.1    Wilm, B.2    Hasegawa, H.3
  • 34
    • 3142757135 scopus 로고    scopus 로고
    • Initial observations on the effect of medium composition on the differentiation of murine embryonic stem cells to alveolar type II cells
    • Rippon HJ, Ali NN, Polak JM et al. Initial observations on the effect of medium composition on the differentiation of murine embryonic stem cells to alveolar type II cells. Cloning Stem Cells 2004;6:49-56.
    • (2004) Cloning Stem Cells , vol.6 , pp. 49-56
    • Rippon, H.J.1    Ali, N.N.2    Polak, J.M.3
  • 35
    • 53349178722 scopus 로고    scopus 로고
    • In vivo reprogramming of adult pancreatic exocrine cells to β-cells
    • Zhou Q, Brown J, Kanarek A et al. In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature 2008;455:627-632.
    • (2008) Nature , vol.455 , pp. 627-632
    • Zhou, Q.1    Brown, J.2    Kanarek, A.3
  • 36
    • 56249127158 scopus 로고    scopus 로고
    • Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages
    • Carraro G, Perin L, Sedrakyan S et al. Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Stem Cells 2008;26:2902-2911.
    • (2008) Stem Cells , vol.26 , pp. 2902-2911
    • Carraro, G.1    Perin, L.2    Sedrakyan, S.3
  • 37
    • 34547907770 scopus 로고    scopus 로고
    • "Stemness" Does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs)
    • Prockop DJ. "Stemness" Does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs). Clin Pharmacol Ther 2007;82:241-243.
    • (2007) Clin Pharmacol Ther , vol.82 , pp. 241-243
    • Prockop, D.J.1
  • 38
    • 34548610480 scopus 로고    scopus 로고
    • Intrapulmonary delivery of bone marrow- Derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice
    • Gupta N, Su X, Popov B et al. Intrapulmonary delivery of bone marrow- derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 2007;179:1855-1863.
    • (2007) J Immunol , vol.179 , pp. 1855-1863
    • Gupta, N.1    Su, X.2    Popov, B.3
  • 39
    • 44549088334 scopus 로고    scopus 로고
    • Bone marrow- Derived cells participate in stromal remodeling of the lung following acute bacterial pneumonia in mice
    • Serikov VB, Mikhaylov VM, Krasnodembskay AD et al. Bone marrow- derived cells participate in stromal remodeling of the lung following acute bacterial pneumonia in mice. Lung 2008;186:179-190.
    • (2008) Lung , vol.186 , pp. 179-190
    • Serikov, V.B.1    Mikhaylov, V.M.2    Krasnodembskay, A.D.3
  • 43
    • 3142736394 scopus 로고    scopus 로고
    • Lung epithelial cells and type II pneumocytes of donor origin after allogeneic hematopoietic stem cell transplantation
    • Mattsson J, Jansson M, Wernerson A et al. Lung epithelial cells and type II pneumocytes of donor origin after allogeneic hematopoietic stem cell transplantation. Transplantation 2004;78:154-157. (Pubitemid 38938300)
    • (2004) Transplantation , vol.78 , Issue.2 , pp. 154-157
    • Mattsson, J.1    Jansson, M.2    Wernerson, A.3    Hassan, M.4
  • 45
    • 65249098301 scopus 로고    scopus 로고
    • Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis
    • Moeller A, Gilpin SE, Ask K et al. Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2009;179:588-594.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 588-594
    • Moeller, A.1    Gilpin, S.E.2    Ask, K.3
  • 46
    • 50849104286 scopus 로고    scopus 로고
    • Resident cellular components of the lung: Developmental aspects
    • Cardoso WV, Whitsett JA. Resident cellular components of the lung: developmental aspects. Proc Am Thorac Soc 2008;5:767-771.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 767-771
    • Cardoso, W.V.1    Whitsett, J.A.2
  • 47
    • 57349176894 scopus 로고    scopus 로고
    • Clinical transplantation of a tissue-engineered airway
    • Macchiarini P, Jungebluth P, Go T et al. Clinical transplantation of a tissue-engineered airway. Lancet 2008;372:2023-2030.
    • (2008) Lancet , vol.372 , pp. 2023-2030
    • Macchiarini, P.1    Jungebluth, P.2    Go, T.3
  • 49
    • 62949220231 scopus 로고    scopus 로고
    • Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
    • Feng B, Ng JH, Heng JC et al. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 2009;4:301-312.
    • (2009) Cell Stem Cell , vol.4 , pp. 301-312
    • Feng, B.1    Ng, J.H.2    Heng, J.C.3
  • 50
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4:381-384.
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 51
    • 48649094116 scopus 로고    scopus 로고
    • Functional live cell imaging of the pulmonary neuroepithelial body microenvironment
    • De Proost I, Pintelon I, Brouns I et al. Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. Am J Respir Cell Mol Biol 2008;39:180-189.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 180-189
    • De Proost, I.1    Pintelon, I.2    Brouns, I.3
  • 52
    • 65249098332 scopus 로고    scopus 로고
    • Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics
    • Teisanu RM, Lagasse E, Whitesides JF et al. Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. Stem Cells 2009;27:612-622.
    • (2009) Stem Cells , vol.27 , pp. 612-622
    • Teisanu, R.M.1    Lagasse, E.2    Whitesides, J.F.3
  • 53
    • 52449128741 scopus 로고    scopus 로고
    • The pipeline: Preparing and training pulmonary scientists for research careers
    • Reynolds HY, Rothgeb A, Colombini-Hatch S et al. The pipeline: preparing and training pulmonary scientists for research careers. Lung 2008;186:279-291.
    • (2008) Lung , vol.186 , pp. 279-291
    • Reynolds, H.Y.1    Rothgeb, A.2    Colombini-Hatch, S.3
  • 54
    • 34447619339 scopus 로고    scopus 로고
    • Lung, and Blood Institute resources and programs for cell-based therapies
    • Thomas JW. National Heart, Lung, and Blood Institute resources and programs for cell-based therapies. Circ Res 2007;101:1-6.
    • (2007) Circ Res , vol.101 , pp. 1-6
    • Thomas, J.W.1    Heart, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.