Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord

Stem Cells

Volumn 22, Issue 7, 2004, Pages 1330-1337

  Wang, Hwai Shi ^a   Hung, Shih Chieh ^a,b   Peng, Shu Tine ^a   Huang, Chun Chieh ^a   Wei, Hung Mu ^a   Guo, Yi Jhih ^a   Fu, Yu Show ^a   Lai, Mei Chun ^a   Chen, Chin Chang ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Mesenchymal stem cells; Multipotent cells; Umbilical cord; Wharton's jelly

Indexed keywords

AZACITIDINE; CELL MARKER; FAT; INTEGRIN; NERVE CELL ADHESION MOLECULE; TROPONIN I;

ARTICLE; BONE; CELL DIFFERENTIATION; CELL LINEAGE; CONNECTIVE TISSUE; FIBROBLAST; FLOW CYTOMETRY; HEART CELL CULTURE; HEART MUSCLE CELL; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MESENCHYME CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; STAINING; STEM CELL; UMBILICAL CORD; WESTERN BLOTTING;

ADIPOCYTES; ANTIGENS, CD; ANTIGENS, CD34; ANTIGENS, CD44; ANTIGENS, CD45; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELLS; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; UMBILICAL CORD; VASCULAR CELL ADHESION MOLECULE-1;

EID: 10444248938     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2004-0013     Document Type: Article

References (36)

1. Meyer FA, Laver-Rudich Z, Tanenbaum R. Evidence for a mechanical coupling of glycoprotein microfibrils with collagen fibrils in Wharton's jelly. Biochim Biophys Acta 1983;755:376-387.
2. Vizza E, Correr S, Goranova V et al. The collagen skeleton of the human umbilical cord at term: a scanning electron microscopy study after 2N-NaOH maceration. Reprod Fertil Dev 1996;8:885-894.
3. Sobolewski K, Bankowski E, Chyczewski L et al. Collagen and glycosaminoglycans of Wharton's jelly. Biol Neonate 1997;71:11-21.
4. Sakamoto T, Ono H, Saito Y. Electron microscopic histochemical studies on the localization of hyaluronic acid in Wharton's jelly of the human umbilical cord [in Japanese]. Nippon Sanka Fujinka Gakkai Zasshi 1996;48:501-507.
5. McElreavey KD, Irvine AI, Ennis KT et al. Isolation, culture and characterisation of fibroblast-like cells derived from the Wharton's jelly portion of human umbilical cord. Biochem Soc Trans 1991;19:29S.
6. Kobayashi K, Kubota T, Aso T. Study on myofibroblast differentiation in the stromal cells of Wharton's jelly : expression and localization of alpha-smooth muscle actin. Early Hum Dev 1998;51:223-233.
7. Mitchell KE, Weiss ML, Mitchell BM et al. Matrix cells from Wharton's jelly form neurons and glia. STEM CELLS 2003;21:50-60.
8. Wang JS, Shum-Tim D, Galipeau J et al. Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages. J Thorac Cardiovasc Surg 2000;120: 999-1005.
9. Friedenstein AJ, Gorskaja JF, Kulagina NN. Fibroblast precursors in normal and irradiated mouse hematopoietic organs. Exp Hematol 1976;4:267-274.
10. Mets T, Verdonk G. In vitro aging of human bone marrow derived stromal cells. Mech Ageing Dev 1981;16:81-89.
11. Owen ME, Friedenstein AJ. Cell and molecular biology of vertebrate hard tissues. Ciba Found Symp 1998;132:42-60.
12. Caplan AI. Mesenchymal stem cells. J Orthop Res 1991;9: 641-650.
13. Clark BR, Keating A. Biology of bone marrow stroma. Ann N Y Acad Sci 1995;770:70-78.
14. Bruder SP, Jaiswal N, Haynesworth SE. Growth kinetics, self-renewal and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J Cell Biochem 1997;64: 278-294.
15. Zohar R, Sodek J, McCulloch CA. Characterization of stromal progenitor cells enriched by flow cytometry. Blood 1997;90:3471-3481.
16. Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
17. Lennon DP, Edmison JM, Caplan SI. Cutlivation of rat marrow-derived mesenchymal stem cells in reduced oxygen tension: effects on in vitro and in vivo osteochondrogenesis. J Cell Physiol 2001;187:345-355.
18. Sekiya I, Vuoristo JT, Larson BL et al. In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc Natl Acad Sci U S A 2002;99:4397-4402.
19. Pereira RF, Halford KW, O'Hara MD et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage and lung in irradiated mice. Proc Natl Acad Sci U S A 1995;92:4857-4861.
20. Pereira RF, O'Hara MD, Laptev AV et al. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proc Natl Acad Sci U S A 1998;95:1142-1147.
21. Ferrari G, Cusella-De Angelis G, Coletta M et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-1530.
22. Sandhu JS, Clark BR, Boynton EL et al. Human hematopoiesis in SCID mice implanted with human adult cancellous bone. Blood 1996;88:1973-1982.
23. Spees JL, Olson SD, Ylostalo J et al. Differentiation, cell fusion and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma. Proc Natl Acad Sci U S A 2003;100:2397-2402.
24. Fukuda K. Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering. Artif Organs 2001;25:187-193.
25. Orlic D, Kajstura J, Chimenti S et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-705.
26. Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM et al. Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 2003;425: 968-973.
27. Hakuno D, Fukuda K, Makino S et al. Bone marrow-derived regenerated cardiomyocytes (CMG cells) express functional adrenergic and muscarinic receptors. Circulation 2002;105:380-386.
28. Volk T, Geiger B. A 135-kd membrane protein of intercellular adherens junctions. EMBO J 1984;3:2249-2260.
29. Volk T, Geiger B. A-CAM: a 135-kD receptor of intercellular adherens junctions, II. Antibody-mediated modulation of junction formation. J Cell Biol 1986;103:1451-1464.
30. Makino S, Fukuda K, Miyoshi S et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999,103:697-705.
31. Irvine AE, Morris TC, Kennedy H et al. Human umbilical cord conditioned medium: a stimulus for human CFU-G. Exp Hematol 1984;12:19-24.
32. Palka J, Bankowski E, Jaworski S. An accumulation of IGF-I and IGF-binding proteins in human umbilical cord. Mol Cell Biochem 2000;206:133-139.
33. Rao CV, Li X, Toth P et al. Expression of epidermal growth factor, transforming growth factor-alpha and their common receptor genes in human umbilical cords. J Clin Endocrinol Metab 1995;80:1012-1020.
34. Majumdar MK, Thiede MA, Mosca JD et al. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells and stromal cells. J Cell Physiol 1998;176:57-66.
35. + hematopoietic progenitor cells. J Cell Physiol 2000;184:58-69.
36. Kadner A, Hoerstrup SP, Tracy J et al. Human umbilical cord cells: a new cell source for cardiovascular tissue engineering. Ann Thorac Surg 2002;74:S1422-S1428.