메뉴 건너뛰기




Volumn 4, Issue 1-2, 2011, Pages 25-33

Neural inflammation and the microglial response in diabetic retinopathy

Author keywords

Diabetic retinopathy; Leukostasis; Microglia

Indexed keywords

ALMADORI GLYCATED ALBUMIN; C REACTIVE PROTEIN; CD18 ANTIGEN; GLUCOCORTICOID; GLYCOSYLATED ALBUMIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR A; TRANSFORMING GROWTH FACTOR BETA1; TRIAMCINOLONE ACETATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84863990408     PISSN: 19368437     EISSN: 19368445     Source Type: Journal    
DOI: 10.1007/s12177-012-9086-x     Document Type: Review
Times cited : (21)

References (98)
  • 2
    • 80355143546 scopus 로고    scopus 로고
    • Microglial cell origin and phenotypes in health and disease
    • doi:710.1038/ nri3086
    • Saijo K, Glass CK. Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol. 2011;11:775-87. doi:710.1038/ nri3086.
    • (2011) Nat Rev Immunol , vol.11 , pp. 775-787
    • Saijo, K.1    Glass, C.K.2
  • 3
    • 33846571886 scopus 로고    scopus 로고
    • The origin and cell lineage of microglia-New concepts
    • DOI 10.1016/j.brainresrev.2006.11.002, PII S0165017306001184
    • Chan WY, Kohsaka S, Rezaie P. The origin and cell lineage of microglia: new concepts. Brain Res Rev. 2007;53:344-54. (Pubitemid 46177241)
    • (2007) Brain Research Reviews , vol.53 , Issue.2 , pp. 344-354
    • Chan, W.Y.1    Kohsaka, S.2    Rezaie, P.3
  • 5
    • 17844392902 scopus 로고    scopus 로고
    • Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy
    • DOI 10.2337/diabetes.54.5.1559
    • Krady JK, Basu A, Allen CM, Xu Y, LaNoue KF, Gardner TW, et al. Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. Diabetes. 2005;54:1559-65. (Pubitemid 40586690)
    • (2005) Diabetes , vol.54 , Issue.5 , pp. 1559-1565
    • Krady, J.K.1    Basu, A.2    Allen, C.M.3    Xu, Y.4    LaNoue, K.F.5    Gardner, T.W.6    Levison, S.W.7
  • 6
    • 34248392684 scopus 로고    scopus 로고
    • Microglial activation and its implications in the brain diseases
    • DOI 10.2174/092986707780597961
    • Dheen ST, Kaur C, Ling EA. Microglial activation and its implications in the brain diseases. Curr Med Chem. 2007;14:1189-97. (Pubitemid 46739320)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.11 , pp. 1189-1197
    • Dheen, S.T.1    Kaur, C.2    Ling, E.-A.3
  • 7
    • 66449130960 scopus 로고    scopus 로고
    • Regulation of innate immune responses in the brain
    • Rivest S. Regulation of innate immune responses in the brain. Nat Rev Immunol. 2009;9:429-39.
    • (2009) Nat Rev Immunol , vol.9 , pp. 429-439
    • Rivest, S.1
  • 8
    • 34547678667 scopus 로고    scopus 로고
    • Mechanisms of over-activated innate immune system regulation in autoimmune and neurodegenerative disorders
    • Blach-Olszewska Z, Leszek J. Mechanisms of over-activated innate immune system regulation in autoimmune and neurodegenerative disorders. Neuropsychiatr Dis Treat. 2007;3:365-72. (Pubitemid 47215011)
    • (2007) Neuropsychiatric Disease and Treatment , vol.3 , Issue.3 , pp. 365-372
    • Blach-Olszewska, Z.1    Leszek, J.2
  • 9
    • 34547127632 scopus 로고    scopus 로고
    • Neuroprotective role of the innate immune system by microglia
    • DOI 10.1016/j.neuroscience.2007.02.055, PII S0306452207002588
    • Glezer I, Simard AR, Rivest S. Neuroprotective role of the innate immune system by microglia. Neuroscience. 2007;147:867-83. Epub 2007 Apr 2024. (Pubitemid 47102534)
    • (2007) Neuroscience , vol.147 , Issue.4 , pp. 867-883
    • Glezer, I.1    Simard, A.R.2    Rivest, S.3
  • 10
    • 77956537707 scopus 로고    scopus 로고
    • Microglia and neuroprotection: From in vitro studies to therapeutic applications
    • Epub 2010 Jul 2014
    • Polazzi E, Monti B. Microglia and neuroprotection: from in vitro studies to therapeutic applications. Prog Neurobiol. 2010;92:293-315. Epub 2010 Jul 2014.
    • (2010) Prog Neurobiol , vol.92 , pp. 293-315
    • Polazzi, E.1    Monti, B.2
  • 11
    • 37049028157 scopus 로고    scopus 로고
    • Neuroprotective effects of resident microglia following acute brain injury
    • DOI 10.1002/cne.21469
    • Simard AR, Rivest S. Neuroprotective effects of resident microglia following acute brain injury. J Comp Neurol. 2007;504:716-29. (Pubitemid 350246584)
    • (2007) Journal of Comparative Neurology , vol.504 , Issue.6 , pp. 716-729
    • Simard, A.R.1    Rivest, S.2
  • 12
    • 0020536689 scopus 로고
    • Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: Phagocytosis of dying neurons and differentiation in microglial cells to form a regular array in the plexiform layers
    • Hume DA, Perry VH, Gordon S. Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: phagocytosis of dying neurons and differentiation of microglial cells to form a regular array in the plexiform layers. J Cell Biol. 1983;97:253-7. (Pubitemid 13076538)
    • (1983) Journal of Cell Biology , vol.97 , Issue.1 , pp. 253-257
    • Hume, D.A.1    Perry, V.H.2    Gordon, S.3
  • 14
    • 53149116704 scopus 로고    scopus 로고
    • Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy
    • Epub 2008 May 4116
    • Lee JE, Liang KJ, Fariss RN,Wong WT. Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy. Invest Ophthalmol Vis Sci. 2008;49:4169-76. Epub 2008 May 4116.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4169-4176
    • Lee, J.E.1    Liang, K.J.2    Fariss, R.N.3    Wong, W.T.4
  • 15
    • 34547645633 scopus 로고    scopus 로고
    • Turnover of resident retinal microglia in the normal adult mouse
    • DOI 10.1002/glia.20535
    • Xu H, Chen M, Mayer EJ, Forrester JV, Dick AD. Turnover of resident retinal microglia in the normal adult mouse. Glia. 2007;55:1189-98. (Pubitemid 47204210)
    • (2007) GLIA , vol.55 , Issue.11 , pp. 1189-1198
    • Xu, H.1    Chen, M.2    Mayer, E.J.3    Forrester, J.V.4    Dick, A.D.5
  • 16
    • 53149128027 scopus 로고    scopus 로고
    • Characteristics of bone marrow-derived microglia in the normal and injured retina
    • Epub 2008 May 4116
    • Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H. Characteristics of bone marrow-derived microglia in the normal and injured retina. Invest Ophthalmol Vis Sci. 2008;49:4162-8. Epub 2008 May 4116.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4162-4168
    • Kaneko, H.1    Nishiguchi, K.M.2    Nakamura, M.3    Kachi, S.4    Terasaki, H.5
  • 17
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • DOI 10.1038/nn2014, PII NN2014
    • Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local selfrenewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci. 2007;10:1538-43. Epub 2007 Nov 1518. (Pubitemid 350175883)
    • (2007) Nature Neuroscience , vol.10 , Issue.12 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.V.5
  • 18
    • 78650233802 scopus 로고    scopus 로고
    • Microglia in the CNS: Immigrants from another world
    • Prinz M, Mildner A. Microglia in the CNS: immigrants from another world. Glia. 2011;59:177-87.
    • (2011) Glia , vol.59 , pp. 177-187
    • Prinz, M.1    Mildner, A.2
  • 20
    • 80052246111 scopus 로고    scopus 로고
    • Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
    • doi:1110.1038/nn.2887
    • Ajami B, Bennett JL, Krieger C, McNagny KM, Rossi FM. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci. 2011;14:1142-9. doi:1110.1038/nn.2887.
    • (2011) Nat Neurosci , vol.14 , pp. 1142-1149
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    McNagny, K.M.4    Rossi, F.M.5
  • 21
    • 84860498105 scopus 로고    scopus 로고
    • History of innate immunity in neurodegenerative disorders
    • Epub 2011 Dec 2012
    • McGeer PL, McGeer EG. History of innate immunity in neurodegenerative disorders. Front Pharmacol. 2011;2:77. Epub 2011 Dec 2012.
    • (2011) Front Pharmacol , vol.2 , pp. 77
    • McGeer, P.L.1    McGeer, E.G.2
  • 22
    • 19744380563 scopus 로고    scopus 로고
    • Neuroscience: Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • DOI 10.1126/science.1110647
    • Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science. 2005;308:1314-8. Epub 2005 Apr 1314. (Pubitemid 40746128)
    • (2005) Science , vol.308 , Issue.5726 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 23
    • 65249157852 scopus 로고    scopus 로고
    • Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
    • Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci. 2009;29:3974-80.
    • (2009) J Neurosci , vol.29 , pp. 3974-3980
    • Wake, H.1    Moorhouse, A.J.2    Jinno, S.3    Kohsaka, S.4    Nabekura, J.5
  • 24
    • 34547519410 scopus 로고    scopus 로고
    • Innate immunity and protective neuroinflammation: New emphasis on the role of neuroimmune regulatory proteins
    • Griffiths M, Neal JW, Gasque P. Innate immunity and protective neuroinflammation: new emphasis on the role of neuroimmune regulatory proteins. Int Rev Neurobiol. 2007;82:29-55.
    • (2007) Int Rev Neurobiol , vol.82 , pp. 29-55
    • Griffiths, M.1    Neal, J.W.2    Gasque, P.3
  • 25
    • 79961011276 scopus 로고    scopus 로고
    • Activation and control of CNS innate immune responses in health and diseases: A balancing act finely tuned by neuroimmune regulators (NIReg)
    • Hoarau JJ, Krejbich-Trotot P, Jaffar-Bandjee MC, Das T, Thon-Hon GV, Kumar S, et al. Activation and control of CNS innate immune responses in health and diseases: a balancing act finely tuned by neuroimmune regulators (NIReg). CNS Neurol Disord Drug Targets. 2011;10:25-43.
    • (2011) CNS Neurol Disord Drug Targets , vol.10 , pp. 25-43
    • Hoarau, J.J.1    Krejbich-Trotot, P.2    Jaffar-Bandjee, M.C.3    Das, T.4    Thon-Hon, G.V.5    Kumar, S.6
  • 26
    • 80355125158 scopus 로고    scopus 로고
    • CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease
    • Zhang S, Wang XJ, Tian LP, Pan J, Lu GQ, Zhang YJ, et al. CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease. J Neuroinflammation. 2011;8:154.
    • (2011) J Neuroinflammation , vol.8 , pp. 154
    • Zhang, S.1    Wang, X.J.2    Tian, L.P.3    Pan, J.4    Lu, G.Q.5    Zhang, Y.J.6
  • 27
    • 80052714655 scopus 로고    scopus 로고
    • CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease
    • Epub 32011 Jul 32719
    • Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, et al. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. J Biol Chem. 2011;286:32713-22. Epub 32011 Jul 32719.
    • (2011) J Biol Chem , vol.286 , pp. 32713-32722
    • Cho, S.H.1    Sun, B.2    Zhou, Y.3    Kauppinen, T.M.4    Halabisky, B.5    Wes, P.6
  • 28
    • 80052315340 scopus 로고    scopus 로고
    • Toll-like receptors in health and disease in the brain: Mechanisms and therapeutic potential
    • Hanke ML, Kielian T. Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clin Sci (Lond). 2011;121:367-87.
    • (2011) Clin Sci (Lond) , vol.121 , pp. 367-387
    • Hanke, M.L.1    Kielian, T.2
  • 29
    • 66049164016 scopus 로고    scopus 로고
    • IFN-gamma receptor signaling mediates spinal microglia activation driving neuropathic pain
    • Epub 2009 Apr 8020
    • Tsuda M, Masuda T, Kitano J, Shimoyama H, Tozaki-Saitoh H, Inoue K. IFN-gamma receptor signaling mediates spinal microglia activation driving neuropathic pain. Proc Natl Acad Sci USA. 2009;106:8032-7. Epub 2009 Apr 8020.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8032-8037
    • Tsuda, M.1    Masuda, T.2    Kitano, J.3    Shimoyama, H.4    Tozaki-Saitoh, H.5    Inoue, K.6
  • 30
    • 35748939409 scopus 로고    scopus 로고
    • Neuronal 'On' and 'Off' signals control microglia
    • DOI 10.1016/j.tins.2007.08.007, PII S0166223607002482
    • Biber K, Neumann H, Inoue K, Boddeke HW. Neuronal 'On' and 'Off' signals control microglia. Trends Neurosci. 2007;30:596-602. Epub 2007 Oct 2024. (Pubitemid 350051426)
    • (2007) Trends in Neurosciences , vol.30 , Issue.11 , pp. 596-602
    • Biber, K.1    Neumann, H.2    Inoue, K.3    Boddeke, H.W.G.M.4
  • 32
    • 0344495393 scopus 로고    scopus 로고
    • Plasminogen-induced IL-1β and TNF-α production in microglia is regulated by reactive oxygen species
    • DOI 10.1016/j.bbrc.2003.11.010
    • Min KJ, Jou I, Joe E. Plasminogen-induced IL-1beta and TNFalpha production in microglia is regulated by reactive oxygen species. Biochem Biophys Res Commun. 2003;312:969-74. (Pubitemid 37490910)
    • (2003) Biochemical and Biophysical Research Communications , vol.312 , Issue.4 , pp. 969-974
    • Min, K.-J.1    Jou, I.2    Joe, E.3
  • 35
    • 70449526190 scopus 로고    scopus 로고
    • Heterogeneity of microglial activation in the innate immune response in the brain
    • Epub 2009 Aug 2005
    • Colton CA. Heterogeneity of microglial activation in the innate immune response in the brain. J Neuroimmune Pharmacol. 2009;4:399-418. Epub 2009 Aug 2005.
    • (2009) J Neuroimmune Pharmacol , vol.4 , pp. 399-418
    • Colton, C.A.1
  • 36
    • 0036884424 scopus 로고    scopus 로고
    • A blast from the past: Clearance of apoptotic cells regulates immune responses
    • DOI 10.1038/nri957
    • Savill J, Dransfield I, Gregory C, Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol. 2002;2:965-75. (Pubitemid 37323217)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.12 , pp. 965-975
    • Savill, J.1    Dransfield, I.2    Gregory, C.3    Haslett, C.4
  • 38
    • 80053322513 scopus 로고    scopus 로고
    • Changes in aqueous concentrations of various cytokines after intravitreal triamcinolone versus bevacizumab for diabetic macular edema
    • Epub 2011 Jul 2022
    • Sohn HJ, Han DH, Kim IT, Oh IK, Kim KH, Lee DY, et al. Changes in aqueous concentrations of various cytokines after intravitreal triamcinolone versus bevacizumab for diabetic macular edema. Am J Ophthalmol. 2011;152:686-94. Epub 2011 Jul 2022.
    • (2011) Am J Ophthalmol , vol.152 , pp. 686-694
    • Sohn, H.J.1    Han, D.H.2    Kim, I.T.3    Oh, I.K.4    Kim, K.H.5    Lee, D.Y.6
  • 39
    • 80755152818 scopus 로고    scopus 로고
    • Intervention with an erythropoietin-derived peptide protects against neuroglial and vascular degeneration during diabetic retinopathy
    • Epub 2011 Sep 2912
    • McVicar CM, Hamilton R, Colhoun LM, Gardiner TA, Brines M, Cerami A, et al. Intervention with an erythropoietin-derived peptide protects against neuroglial and vascular degeneration during diabetic retinopathy. Diabetes. 2011;60:2995-3005. Epub 2011 Sep 2912.
    • (2011) Diabetes , vol.60 , pp. 2995-3005
    • McVicar, C.M.1    Hamilton, R.2    Colhoun, L.M.3    Gardiner, T.A.4    Brines, M.5    Cerami, A.6
  • 40
    • 79955919145 scopus 로고    scopus 로고
    • A(A) adenosine receptor (A(A)AR) as a therapeutic target in diabetic retinopathy
    • Ibrahim AS, El-Shishtawy MM, Zhang W, Caldwell RB, Liou GI. A(A) adenosine receptor (A(A)AR) as a therapeutic target in diabetic retinopathy. Am J Pathol. 2011;178:2136-45.
    • (2011) Am J Pathol , vol.178 , pp. 2136-2145
    • Ibrahim, A.S.1    El-Shishtawy, M.M.2    Zhang, W.3    Caldwell, R.B.4    Liou, G.I.5
  • 42
    • 79955943133 scopus 로고    scopus 로고
    • TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis
    • Print 2011 Mar
    • Huang H, Gandhi JK, Zhong X, Wei Y, Gong J, Duh EJ, et al. TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis. Invest Ophthalmol Vis Sci. 2011;52:1336-44. Print 2011 Mar.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 1336-1344
    • Huang, H.1    Gandhi, J.K.2    Zhong, X.3    Wei, Y.4    Gong, J.5    Duh, E.J.6
  • 43
    • 77956380383 scopus 로고    scopus 로고
    • Muller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage
    • Epub 2010 Jun 2298
    • Wang J, Xu X, Elliott MH, Zhu M, Le YZ. Muller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage. Diabetes. 2010;59:2297-305. Epub 2010 Jun 2298.
    • (2010) Diabetes , vol.59 , pp. 2297-2305
    • Wang, J.1    Xu, X.2    Elliott, M.H.3    Zhu, M.4    Le, Y.Z.5
  • 44
    • 80052554460 scopus 로고    scopus 로고
    • Ischaemiainduced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Muller cells
    • Epub 2011 Mar 1551
    • Lin M, Chen Y, Jin J, Hu Y, Zhou KK, Zhu M, et al. Ischaemiainduced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Muller cells. Diabetologia. 2011;54:1554-66. Epub 2011 Mar 1551.
    • (2011) Diabetologia , vol.54 , pp. 1554-1566
    • Lin, M.1    Chen, Y.2    Jin, J.3    Hu, Y.4    Zhou, K.K.5    Zhu, M.6
  • 45
    • 0025915186 scopus 로고
    • Retinal microglia: A new cell in idiopathic proliferative vitreoretinopathy?
    • Weller M, Esser P, Heimann K, Wiedemann P. Retinal microglia: a new cell in idiopathic proliferative vitreoretinopathy? Exp Eye Res. 1991;53:275-81.
    • (1991) Exp Eye Res , vol.53 , pp. 275-281
    • Weller, M.1    Esser, P.2    Heimann, K.3    Wiedemann, P.4
  • 47
    • 79551549280 scopus 로고    scopus 로고
    • Hyalocytes: Essential cells of the vitreous cavity in vitreoretinal pathophysiology?
    • Sakamoto T, Ishibashi T. Hyalocytes: essential cells of the vitreous cavity in vitreoretinal pathophysiology? Retina. 2011;31:222-8.
    • (2011) Retina , vol.31 , pp. 222-228
    • Sakamoto, T.1    Ishibashi, T.2
  • 48
    • 79954986853 scopus 로고    scopus 로고
    • Circulating bone-marrow-derived endothelial precursor cells contribute to neovascularization in diabetic epiretinal membranes
    • doi:210.1111/j.1755-3768.2009.01700.x
    • Abu El-Asrar AM, Struyf S, Verbeke H, Van Damme J, Geboes K. Circulating bone-marrow-derived endothelial precursor cells contribute to neovascularization in diabetic epiretinal membranes. Acta Ophthalmol. 2011;89:222-8. doi:210.1111/j.1755-3768.2009.01700.x.
    • (2011) Acta Ophthalmol , vol.89 , pp. 222-228
    • Abu El-Asrar, A.M.1    Struyf, S.2    Verbeke, H.3    Van Damme, J.4    Geboes, K.5
  • 49
    • 39049127031 scopus 로고    scopus 로고
    • Microglial activation in human diabetic retinopathy
    • DOI 10.1001/archophthalmol.2007.65
    • Zeng HY, Green WR, Tso MO. Microglial activation in human diabetic retinopathy. Arch Ophthalmol. 2008;126:227-32. (Pubitemid 351240852)
    • (2008) Archives of Ophthalmology , vol.126 , Issue.2 , pp. 227-232
    • Zeng, H.-Y.1    Green, W.R.2    Tso, M.O.M.3
  • 50
    • 80052365841 scopus 로고    scopus 로고
    • The innate immune system and the clearance of apoptotic cells
    • Epub 2011 May 2011
    • Devitt A, Marshall LJ. The innate immune system and the clearance of apoptotic cells. J Leukoc Biol. 2011;90:447-57. Epub 2011 May 2011.
    • (2011) J Leukoc Biol , vol.90 , pp. 447-457
    • Devitt, A.1    Marshall, L.J.2
  • 51
    • 80755152818 scopus 로고    scopus 로고
    • Intervention with an erythropoietin-derived peptide protects against neuroglial and vascular degeneration during diabetic retinopathy
    • McVicar CM, Hamilton R, Colhoun LM, Gardiner TA, Brines M, et al. Intervention with an erythropoietin-derived peptide protects against neuroglial and vascular degeneration during diabetic retinopathy. Diabetes. 2011;60(11):2995-3005.
    • (2011) Diabetes , vol.60 , Issue.11 , pp. 2995-3005
    • McVicar, C.M.1    Hamilton, R.2    Colhoun, L.M.3    Gardiner, T.A.4    Brines, M.5
  • 52
    • 65449157994 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats
    • Epub 2009 Feb 2003
    • Tsai GY, Cui JZ, Syed H, Xia Z, Ozerdem U, McNeill JH, et al. Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats. Clin Experiment Ophthalmol. 2009;37:223-31. Epub 2009 Feb 2003.
    • (2009) Clin Experiment Ophthalmol , vol.37 , pp. 223-231
    • Tsai, G.Y.1    Cui, J.Z.2    Syed, H.3    Xia, Z.4    Ozerdem, U.5    McNeill, J.H.6
  • 53
    • 34447290842 scopus 로고    scopus 로고
    • Hypertension increases retinal inflammation in experimental diabetes: A possible mechanism for aggravation of diabetic retinopathy by hypertension
    • DOI 10.1080/02713680701435391, PII 779875559
    • Silva KC, Pinto CC, Biswas SK, de Faria JB, de Faria JM. Hypertension increases retinal inflammation in experimental diabetes: a possible mechanism for aggravation of diabetic retinopathy by hypertension. Curr Eye Res. 2007;32:533-41. (Pubitemid 47039108)
    • (2007) Current Eye Research , vol.32 , Issue.6 , pp. 533-541
    • Silva, K.C.1    Pinto, C.C.2    Biswas, S.K.3    De Faria, J.B.L.4    De Faria, J.M.L.5
  • 54
    • 0033921527 scopus 로고    scopus 로고
    • Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats
    • Zeng XX, Ng YK, Ling EA. Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats. Vis Neurosci. 2000;17:463-71.
    • (2000) Vis Neurosci , vol.17 , pp. 463-471
    • Zeng, X.X.1    Ng, Y.K.2    Ling, E.A.3
  • 58
    • 80051599575 scopus 로고    scopus 로고
    • AGEs, RAGE, and diabetic retinopathy
    • Zong H, Ward M, Stitt AW. AGEs, RAGE, and diabetic retinopathy. Curr Diab Rep. 2011;11:244-52.
    • (2011) Curr Diab Rep , vol.11 , pp. 244-252
    • Zong, H.1    Ward, M.2    Stitt, A.W.3
  • 60
    • 79960190061 scopus 로고    scopus 로고
    • Inflammation in diabetic retinopathy
    • Epub 2011 May 2025
    • Tang J, Kern TS. Inflammation in diabetic retinopathy. Prog Retin Eye Res. 2011;30:343-58. Epub 2011 May 2025.
    • (2011) Prog Retin Eye Res , vol.30 , pp. 343-358
    • Tang, J.1    Kern, T.S.2
  • 61
    • 17444405235 scopus 로고    scopus 로고
    • Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes - The EURODIAB Prospective Complications Study
    • DOI 10.1007/s00125-004-1628-8
    • Schram MT, Chaturvedi N, Schalkwijk CG, Fuller JH, Stehouwer CD. Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes-the EURODIAB Prospective Complications Study. Diabetologia. 2005;48:370-8. Epub 2005 Feb 2004. (Pubitemid 40543311)
    • (2005) Diabetologia , vol.48 , Issue.2 , pp. 370-378
    • Schram, M.T.1    Chaturvedi, N.2    Schalkwijk, C.G.3    Fuller, J.H.4    Stehouwer, C.D.A.5
  • 62
    • 69549112950 scopus 로고    scopus 로고
    • Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: The multi-ethnic study of atherosclerosis
    • Epub 2009 Jun 1723
    • Nguyen TT, Alibrahim E, Islam FM, Klein R, Klein BE, Cotch MF, et al. Inflammatory, hemostatic, and other novel biomarkers for diabetic retinopathy: the multi-ethnic study of atherosclerosis. Diabetes Care. 2009;32:1704-9. Epub 2009 Jun 1723.
    • (2009) Diabetes Care , vol.32 , pp. 1704-1709
    • Nguyen, T.T.1    Alibrahim, E.2    Islam, F.M.3    Klein, R.4    Klein, B.E.5    Cotch, M.F.6
  • 63
    • 70349243143 scopus 로고    scopus 로고
    • The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy
    • Klein BE, Knudtson MD, Tsai MY, Klein R. The relation of markers of inflammation and endothelial dysfunction to the prevalence and progression of diabetic retinopathy: Wisconsin epidemiologic study of diabetic retinopathy. Arch Ophthalmol. 2009;127:1175-82.
    • (2009) Arch Ophthalmol , vol.127 , pp. 1175-1182
    • Klein, B.E.1    Knudtson, M.D.2    Tsai, M.Y.3    Klein, R.4
  • 68
    • 79953188707 scopus 로고    scopus 로고
    • Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes
    • Epub 2011 Feb 1111
    • Ibrahim AS, El-Remessy AB, Matragoon S, Zhang W, Patel Y, Khan S, et al. Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes. Diabetes. 2011;60:1122-33. Epub 2011 Feb 1111.
    • (2011) Diabetes , vol.60 , pp. 1122-1133
    • Ibrahim, A.S.1    El-Remessy, A.B.2    Matragoon, S.3    Zhang, W.4    Patel, Y.5    Khan, S.6
  • 69
    • 0036847840 scopus 로고    scopus 로고
    • Role of p38 and p44/42 mitogen-activated protein kinases in microglia
    • DOI 10.1002/glia.10151
    • Koistinaho M, Koistinaho J. Role of p38 and p44/42 mitogenactivated protein kinases in microglia. Glia. 2002;40:175-83. (Pubitemid 35337375)
    • (2002) GLIA , vol.40 , Issue.2 , pp. 175-183
    • Koistinaho, M.1    Koistinaho, J.2
  • 70
    • 78149472989 scopus 로고    scopus 로고
    • Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation
    • Ibrahim AS, El-Shishtawy MM, Pena Jr A, Liou GI. Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation. Mol Vis. 2010;16:2033-42.
    • (2010) Mol Vis , vol.16 , pp. 2033-2042
    • Ibrahim, A.S.1    El-Shishtawy, M.M.2    Pena Jr., A.3    Liou, G.I.4
  • 71
    • 35148887143 scopus 로고    scopus 로고
    • Comment on AGEs mediated expression and secretion of TNF alpha in rat retinal microglia by Dr Wang et al
    • DOI 10.1016/j.exer.2007.07.007, PII S0014483507001960
    • Schalkwijk CG. Comment on "AGEs mediated expression and secretion of TNF alpha in rat retinal microglia" by Dr Wang et al. Exp Eye Res. 2007;85:572-3. author reply 574. Epub 2007 Jul 2015. (Pubitemid 47534205)
    • (2007) Experimental Eye Research , vol.85 , Issue.4 , pp. 572-573
    • Schalkwijk, C.G.1
  • 72
    • 68149164365 scopus 로고    scopus 로고
    • Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages
    • Epub 2009 Jul 2113
    • McColl A, Bournazos S, Franz S, Perretti M, Morgan BP, Haslett C, et al. Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages. J Immunol. 2009;183:2167-75. Epub 2009 Jul 2113.
    • (2009) J Immunol , vol.183 , pp. 2167-2175
    • McColl, A.1    Bournazos, S.2    Franz, S.3    Perretti, M.4    Morgan, B.P.5    Haslett, C.6
  • 73
    • 0043172315 scopus 로고    scopus 로고
    • Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: Implications for the resolution of inflammation
    • DOI 10.1677/joe.0.1780029
    • Heasman SJ, Giles KM, Ward C, Rossi AG, Haslett C, Dransfield I. Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation. J Endocrinol. 2003;178:29-36. (Pubitemid 36927006)
    • (2003) Journal of Endocrinology , vol.178 , Issue.1 , pp. 29-36
    • Heasman, S.J.1    Giles, K.M.2    Ward, C.3    Rossi, A.G.4    Haslett, C.5    Dransfield, I.6
  • 74
    • 0041669300 scopus 로고    scopus 로고
    • Corticosteroids, eosinophils and bronchial epithelial cells: New insights into the resolution of inflammation in asthma
    • DOI 10.1677/joe.0.1780037
    • Walsh GM, Sexton DW, Blaylock MG. Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma. J Endocrinol. 2003;178:37-43. (Pubitemid 36927007)
    • (2003) Journal of Endocrinology , vol.178 , Issue.1 , pp. 37-43
    • Walsh, G.M.1    Sexton, D.W.2    Blaylock, M.G.3
  • 75
    • 77952865796 scopus 로고    scopus 로고
    • Phagocyte partnership during the onset and resolution of inflammation
    • Soehnlein O, Lindbom L. Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol. 2010;10:427-39.
    • (2010) Nat Rev Immunol , vol.10 , pp. 427-439
    • Soehnlein, O.1    Lindbom, L.2
  • 76
    • 78149438403 scopus 로고    scopus 로고
    • Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice
    • Saederup N, Cardona AE, Croft K, Mizutani M, Cotleur AC, Tsou CL, et al. Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One. 2010;5:e13693.
    • (2010) PLoS One , vol.5
    • Saederup, N.1    Cardona, A.E.2    Croft, K.3    Mizutani, M.4    Cotleur, A.C.5    Tsou, C.L.6
  • 77
    • 0025769620 scopus 로고
    • Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy
    • Schroder S, Palinski W, Schmid-Schonbein GW. Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy. Am J Pathol. 1991;139:81-100.
    • (1991) Am J Pathol , vol.139 , pp. 81-100
    • Schroder, S.1    Palinski, W.2    Schmid-Schonbein, G.W.3
  • 78
    • 0036216417 scopus 로고    scopus 로고
    • Is diabetic retinopathy an inflammatory disease?
    • DOI 10.1136/bjo.86.4.363
    • Adamis AP. Is diabetic retinopathy an inflammatory disease? Br J Ophthalmol. 2002;86:363-5. (Pubitemid 34293277)
    • (2002) British Journal of Ophthalmology , vol.86 , Issue.4 , pp. 363-365
    • Adamis, A.P.1
  • 79
    • 73249115843 scopus 로고    scopus 로고
    • Targeting leukostasis for the treatment of early diabetic retinopathy
    • Patel N. Targeting leukostasis for the treatment of early diabetic retinopathy. Cardiovasc Hematol Disord Drug Targets. 2009;9:222-9.
    • (2009) Cardiovasc Hematol Disord Drug Targets , vol.9 , pp. 222-229
    • Patel, N.1
  • 81
    • 0036174019 scopus 로고    scopus 로고
    • Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo
    • Joussen AM, Poulaki V, Qin W, Kirchhof B, Mitsiades N, Wiegand SJ, et al. Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am J Pathol. 2002;160:501-9. (Pubitemid 34160327)
    • (2002) American Journal of Pathology , vol.160 , Issue.2 , pp. 501-509
    • Joussen, A.M.1    Poulaki, V.2    Qin, W.3    Kirchhof, B.4    Mitsiades, N.5    Wiegand, S.J.6    Rudge, J.7    Yancopoulos, G.D.8    Adamis, A.P.9
  • 85
    • 77954331063 scopus 로고    scopus 로고
    • Leucocyte/endothelium interactions and microvessel permeability: Coupled or uncoupled?
    • Epub 2010 May 2013
    • He P. Leucocyte/endothelium interactions and microvessel permeability: coupled or uncoupled? Cardiovasc Res. 2010;87:281-90. Epub 2010 May 2013.
    • (2010) Cardiovasc Res , vol.87 , pp. 281-290
    • He, P.1
  • 86
    • 0037271803 scopus 로고    scopus 로고
    • Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes
    • Epub 2002 Nov 2015
    • Joussen AM, Poulaki V, Mitsiades N, Cai WY, Suzuma I, Pak J, et al. Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes. FASEB J. 2003;17:76-8. Epub 2002 Nov 2015.
    • (2003) FASEB J , vol.17 , pp. 76-78
    • Joussen, A.M.1    Poulaki, V.2    Mitsiades, N.3    Cai, W.Y.4    Suzuma, I.5    Pak, J.6
  • 87
    • 77649273140 scopus 로고    scopus 로고
    • Role of chemokines in CNS health and pathology: A focus on the CCL2/CCR2 and CXCL8/CXCR2 networks
    • Epub 2009 Nov 2011
    • Semple BD, Kossmann T, Morganti-Kossmann MC. Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. J Cereb Blood Flow Metab. 2010;30:459-73. Epub 2009 Nov 2011.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 459-473
    • Semple, B.D.1    Kossmann, T.2    Morganti-Kossmann, M.C.3
  • 88
    • 0024421453 scopus 로고
    • Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils
    • Baggiolini M, Walz A, Kunkel SL. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest. 1989;84:1045-9. (Pubitemid 19247571)
    • (1989) Journal of Clinical Investigation , vol.84 , Issue.4 , pp. 1045-1049
    • Baggiolini, M.1    Walz, A.2    Kunkel, S.L.3
  • 89
    • 0029761934 scopus 로고    scopus 로고
    • Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines
    • DOI 10.1016/0306-4522(96)00083-8
    • Bell MD, Taub DD, Perry VH. Overriding the brain's intrinsic resistance to leukocyte recruitment with intraparenchymal injections of recombinant chemokines. Neuroscience. 1996;74:283-92. (Pubitemid 26291164)
    • (1996) Neuroscience , vol.74 , Issue.1 , pp. 283-292
    • Bell, M.D.1    Taub, D.D.2    Perry, V.H.3
  • 90
    • 0037155913 scopus 로고    scopus 로고
    • Vascular endothelial growth factor modulates neutrophil transendothelial migration via up-regulation of interleukin-8 in human brain microvascular endothelial cells
    • DOI 10.1074/jbc.M107348200
    • Lee TH, Avraham H, Lee SH, Avraham S. Vascular endothelial growth factor modulates neutrophil transendothelial migration via up-regulation of interleukin-8 in human brain microvascular endothelial cells. J Biol Chem. 2002;277:10445-51. Epub 12002 Jan 10449. (Pubitemid 34968165)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.12 , pp. 10445-10451
    • Lee, T.-H.1    Avraham, H.2    Lee, S.-H.3    Avraham, S.4
  • 91
    • 77955090344 scopus 로고    scopus 로고
    • Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS
    • Epub 2010 May 2031
    • Prinz M, Priller J. Tickets to the brain: role of CCR2 and CX3CR1 in myeloid cell entry in the CNS. J Neuroimmunol. 2010;224:80-4. Epub 2010 May 2031.
    • (2010) J Neuroimmunol , vol.224 , pp. 80-84
    • Prinz, M.1    Priller, J.2
  • 92
    • 27644570209 scopus 로고    scopus 로고
    • CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2
    • DOI 10.1016/j.mvr.2005.04.005, PII S0026286205000518
    • Dzenko KA, Song L, Ge S, Kuziel WA, Pachter JS. CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2. Microvasc Res. 2005;70:53-64. Epub 2005 May 2031. (Pubitemid 41565409)
    • (2005) Microvascular Research , vol.70 , Issue.1-2 , pp. 53-64
    • Dzenko, K.A.1    Song, L.2    Ge, S.3    Kuziel, W.A.4    Pachter, J.S.5
  • 94
    • 67049114123 scopus 로고    scopus 로고
    • Cooperative phagocytes: Resident microglia and bone marrow immigrants remove dead photoreceptors in retinal lesions
    • Epub 2009 May 2312
    • Joly S, Francke M, Ulbricht E, Beck S, Seeliger M, Hirrlinger P, et al. Cooperative phagocytes: resident microglia and bone marrow immigrants remove dead photoreceptors in retinal lesions. Am J Pathol. 2009;174:2310-23. Epub 2009 May 2312.
    • (2009) Am J Pathol , vol.174 , pp. 2310-2323
    • Joly, S.1    Francke, M.2    Ulbricht, E.3    Beck, S.4    Seeliger, M.5    Hirrlinger, P.6
  • 95
    • 79956028114 scopus 로고    scopus 로고
    • Early focal expression of the chemokine Ccl2 by Muller cells during exposure to damageinducing bright continuous light
    • Print 2011 Apr
    • Rutar M, Natoli R, Valter K, Provis JM. Early focal expression of the chemokine Ccl2 by Muller cells during exposure to damageinducing bright continuous light. Invest Ophthalmol Vis Sci. 2011;52:2379-88. Print 2011 Apr.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 2379-2388
    • Rutar, M.1    Natoli, R.2    Valter, K.3    Provis, J.M.4
  • 97
    • 84862833229 scopus 로고    scopus 로고
    • Elevated systemic neutrophil count in diabetic retinopathy and diabetes: A hospitalbased cross-sectional study of 30,793 Korean subjects
    • Print 2011 Sep
    • Woo SJ, Ahn SJ, Ahn J, Park KH, Lee K. Elevated systemic neutrophil count in diabetic retinopathy and diabetes: a hospitalbased cross-sectional study of 30,793 Korean subjects. Invest Ophthalmol Vis Sci. 2011;52:7697-703. Print 2011 Sep.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 7697-7703
    • Woo, S.J.1    Ahn, S.J.2    Ahn, J.3    Park, K.H.4    Lee, K.5
  • 98
    • 34248663234 scopus 로고    scopus 로고
    • Expression of CD18 on the neutrophils of patients with diabetic retinopathy
    • DOI 10.1007/s00417-006-0379-2
    • Song H, Wang L, Hui Y. Expression of CD18 on the neutrophils of patients with diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol. 2007;245:24-31. Epub 2006 Jul 2018. (Pubitemid 46766726)
    • (2007) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.245 , Issue.1 , pp. 24-31
    • Song, H.1    Wang, L.2    Hui, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.