Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice

FASEB Journal

Volumn 19, Issue 7, 2005, Pages 761-772

  Huang, DeRen ^a   Wujek, Jerome ^a,f   Kidd, Graham ^a   He, Toby T ^a   Cardona, Astrid ^a   Sasse, Margaret E ^a   Stein, Erica J ^a   Kish, Jacqueline ^a   Tani, Marie ^a   Charo, Israel F ^b   Proudfoot, Amanda E ^c   Rollins, Barrett J ^d   Handel, Tracy ^e   Ransohoff, Richard M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^c SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Chemokine receptors; Chemokines; Macrophages; Transgenic mice

Indexed keywords

CD11B ANTIGEN; CD40 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR2; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCOPROTEIN P 15095; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DISEASE; CELL FUNCTION; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOREACTIVITY; MICROGLIA; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ANIMALS; ANTIGENS, CD45; AUTOIMMUNITY; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CEREBRAL CORTEX; CHEMOKINE CCL2; CROSSES, GENETIC; FLOW CYTOMETRY; GENE EXPRESSION; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MICROSCOPY, CONFOCAL; MYELIN PROTEINS; NERVOUS SYSTEM DISEASES; NEUROFILAMENT PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; SPINAL CORD;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MUS MUSCULUS;

EID: 20944435318     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.04-3104com     Document Type: Article

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