Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)

Journal of Biological Chemistry

Volumn 287, Issue 29, 2012, Pages 24427-24437

  Werneburg, Nathan W ^a   Bronk, Steve F ^a   Guicciardi, Maria Eugenia ^a   Thomas, Laurel ^b   Dikeakos, Jimmy D ^b   Thomas, Gary ^b   Gores, Gregory J ^a  

^a MAYO CLINIC   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASES; CATHEPSIN B; CELL SURVIVAL; CYTOSOLS; ENDOSOMES; HUH-7 CELLS; IMMUNOPRECIPITATABLE COMPLEXES; IN-VITRO; INDUCED APOPTOSIS; LIVER CANCER CELLS; LYSOSOMAL MEMBRANES; MEMBRANE PERMEABILIZATION; PERMEABILIZATION; TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGANDS;

CELL CULTURE; GLYCOPROTEINS; LIGANDS; MACROPHAGES; MEMBRANES; PROTEINS;

CELL DEATH;

BIM PROTEIN; CATHEPSIN B; DEATH RECEPTOR 5; PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN 2; PROTEIN BAX; PROTEIN BID; REGULATOR PROTEIN; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; ENDOSOME; HEPATOMA CELL; IN VITRO STUDY; LYSOSOME; LYSOSOME MEMBRANE; LYSOSOME MEMBRANE PERMEABILIZATION; MEMBRANE BIOLOGY; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CATHEPSIN B; CELL LINE, TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOPRECIPITATION; LYSOSOMES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; VESICULAR TRANSPORT PROTEINS;

EID: 84863809112     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.342238     Document Type: Article

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