Enhanced phosphorylation of MAPKs by NE promotes TNF-α production by macrophage through α adrenergic receptor

Inflammation

Volumn 35, Issue 2, 2012, Pages 527-534

  Huang, Jun Long ^a   Zhang, You Lei ^a   Wang, Cheng Cai ^b   Zhou, Jiang Rui ^a   Ma, Qian ^a   Wang, Xia ^a   Shen, Xing Hua ^a   Jiang, Chun Lei ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Inflammatory factors; Macrophages; Mitogen activated protein kinases; Norepinephrine

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA ADRENERGIC RECEPTOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NORADRENALIN; PHENTOLAMINE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; STRESS;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANTHRACENES; BUTADIENES; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; NOREPINEPHRINE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENTOLAMINE; PHOSPHORYLATION; PYRIDINES; RECEPTORS, ADRENERGIC, ALPHA; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84863782750     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-011-9342-4     Document Type: Article

References (30)

1. Miksa, M., P. Das, M. Zhou, R. Wu, W. Dong, Y. Ji, et al. 2009. Pivotal role of the alpha(2A)-adrenoceptor in producing inflammation and organ injury in a rat model of sepsis. PLoS ONE 4: e5504.
2. Oberholzer, A., C. Oberholzer, and L.L. Moldawer. 2001. Sepsis syndromes: understanding the role of innate and acquired immunity. Shock 16: 83-96. (Pubitemid 33596740)
3. Beutler, B., and A. Poltorak. 2001. Sepsis and evolution of the innate immune response. Critical Care Medicine 29: S2-S6.
4. Cook, D.N., D.S. Pisetsky, and D.A. Schwartz. 2004. Toll-like receptors in the pathogenesis of human disease. Nature Immunology 5: 975-979. (Pubitemid 41057713)
5. Naugler, W.E., T. Sakurai, S. Kim, S. Maeda, K. Kim, A.M. Elsharkawy, et al. 2007. Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317: 121-124. (Pubitemid 47056470)
6. Chávez-Sánchez, L., A. Madrid-Miller, K. Chávez-Rueda, M.V. Legorreta-Haquet, E. Tesoro-Cruz, and F. Blanco-Favela. 2010. Activation of TLR2 and TLR4 by minimally modified low-density lipoprotein in human macrophages and monocytes triggers the inflammatory response. Human Immunology 71: 737-744.
7. Flierl, M.A., D. Rittirsch, B.A. Nadeau, A.J. Chen, J.V. Sarma, F.S. Zetoune, et al. 2007. Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature 449: 721-726.
8. Guha, M., and N. Mackman. 2001. LPS induction of gene expression in human monocytes. Cellular Signalling 13: 85-94. (Pubitemid 32222977)
9. Dower, S.K., and E.E. Qwarnstrom. 2003. Signalling networks, inflammation and innate immunity. Biochemical Society Transactions 31: 1462-1471. (Pubitemid 38031002)
10. Geppert, T.D., C.E. Whitehurst, P. Thompson, and B. Beutler. 1994. Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway. Molecular Medicine 1: 93-103.
11. Ci, X., Y. Song, F. Zeng, X. Zhang, H. Li, X. Wang, et al. 2008. Ceftiofur impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-kappaB and MAPK. Biochemical and Biophysical Research Communications 372: 73-77.
12. Kim, K., O. Duramad, X.F. Qin, and B. Su. 2007. MEKK3 is essential for lipopolysaccharide- induced interleukin-6 and granulocyte-macrophage colony-stimulating factor production in macrophages. Immunology 120: 242-250. (Pubitemid 46046322)
13. Davel, A.P., L.E. Fukuda, L.L. De Sá, C.D. Munhoz, C. Scavone, D. Sanz-Rosa, et al. 2008. Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta. American Journal of Physiology. Heart and Circulatory Physiology 295: 211-219.
14. Rose, D.M., B.W. Winston, E.D. Chan, D.W. Riches, and P.M. Henson. 1997. Interferon-gamma and transforming growth factor-beta modulate the activation of mitogen-activated protein kinases and tumor necrosis factor-alpha production induced by Fc gamma-receptor stimulation in murine macrophages. Biochemical and Biophysical Research Communications 238: 256-260. (Pubitemid 27453311)
15. Gosain, A., K. Muthu, R.L. Gamelli, and L.A. DiPietro. 2007. Norepinephrine suppresses wound macrophage phagocytic efficiency through alpha- and beta-adrenoreceptor dependent pathways. Surgery 142: 170-179. (Pubitemid 47198679)
16. Miksa, M., R. Wu, M. Zhou, and P. Wang. 2005. Sympathetic excitotoxicity in sepsis: pro-inflammatory priming of macrophages by norepinephrine. Frontiers in Bioscience 10: 2217-2229. (Pubitemid 40905293)
17. Maestroni, G.J., and P. Mazzola. 2003. Langerhans cells β2-adrenoceptors: role in migration, cytokine production, Th priming and contact hypersensitivity. Journal of Neuroimmunology 144: 91-99. (Pubitemid 37329933)
18. Spooren, A., R. Kooijman, B. Lintermans, K. Van Craenenbroeck, L. Vermeulen, G. Haegeman, et al. 2010. Cooperation of NFkappaB and CREB to induce synergistic IL-6 expression in astrocytes. Cellular Signalling 22: 871-881.
19. Spengler, R.N., S.W. Chensue, D.A. Giacherio, N. Blenk, and S.L. Kunkel. 1994. Endogenous norepinephrine regulates tumor necrosis factor-alpha production from macrophages in vitro. Journal of Immunology 152: 3024-3031. (Pubitemid 24098001)
20. Flierl, M.A., D. Rittirsch, M. Huber-Lang, J.V. Sarma, and P.A. Ward. 2008. Catecholamines-crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening pandora's box? Molecular Medicine 14: 195-204. (Pubitemid 351481850)
21. Spengler, R.N., R.M. Allen, D.G. Remick, R.M. Strieter, and S.L. Kunkel. 1990. Stimulation of alpha-adrenergic receptor augments the production of macrophage derived tumor necrosis factor. Journal of Immunology 145: 1430-1434. (Pubitemid 20255049)
22. d-adrenergic receptor subtypes in human monocytes. Journal of Neuroimmunology 95: 165-173.
23. Severn, A., N.T. Rapson, C.A. Hunter, and F.Y. Liew. 1992. Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists. Journal of Immunology 148: 3441-3445.
24. Bylund, D.B., D.C. Eikenberg, J.P. Hieble, S.Z. Langer, R.J. Lefkowitz, K.P. Minneman, et al. 1994. IV. International Union of Pharmacology nomenclature of adrenoceptors. Pharmacological Reviews 46: 121-136.
25. Rouppe van der Voort, C., A. Kavelaars, M. van de Pol, and C.J. Heijnen. 2000. Noradrenaline induces phosphorylation of ERK-2 in human peripheral blood mononuclear cells after induction of alpha(1)-adrenergic receptors. Journal of Neuroimmunology 108 (1-2): 82-91. (Pubitemid 30438755)
26. Elenkov, I.J., R.L. Wilder, G.P. Chrousos, and E.S. Vizi. 2000. The sympathetic nerve-an integrative interface between two super-systems: the brain and the immune system. Pharmacological Reviews 52: 595-638.
27. Yang, S., D.J. Koo, M. Zhou, I.H. Chaudry, and P. Wang. 2000. Gut-derived norepinephrine plays a critical role in producing hepatocellular dysfunction during early sepsis. American Journal of Physiology. Gastrointestinal and Liver Physiology 279: G1274-G1281.
28. Jiang, J.L., Y.H. Qiu, Y.P. Peng, and J.J. Wang. 2006. Immunoregulatory role of endogenous catecholamines synthesized by immune cells. Sheng Li Xue Bao 58: 309-317.
29. Sternberg, E.M. 2006. Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nature Reviews. Immunology 6: 318-328.
30. Wang, H., M. Yu, M. Ochani, C.A. Amella, M. Tanovic, S. Susarla, et al. 2003. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421: 384-388. (Pubitemid 36157937)