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Volumn 10, Issue SUPPL. 1, 2005, Pages 2217-2229

Sympathetic excitotoxicity in sepsis: Pro-inflammatory priming of macrophages by norepinephrine

Author keywords

Alpha2A Adrenoceptor; Ghrelin; Inflammation; Kupffer cells; Macrophages; Norepinephrine; Review; Sepsis; Sympathetic Nervous System

Indexed keywords

4 AMINOBUTYRIC ACID; ADRENALIN; ADRENERGIC RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; CATECHOLAMINE; CHOLINERGIC RECEPTOR; GHRELIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTRANSMITTER; NORADRENALIN; PEPTIDE; RECEPTOR BLOCKING AGENT;

EID: 21344441265     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1691     Document Type: Review
Times cited : (65)

References (94)
  • 1
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • Martin, G. S., D. M. Mannino, S. Eaton & M. Moss: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med, 348, 1546-54 (2003)
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 2
    • 11344281556 scopus 로고    scopus 로고
    • An international sepsis survey: A study of doctors' knowledge and perception about sepsis
    • Poeze, M., G. Ramsay, H. Gerlach, F. Rubulotta & M. Levy: An international sepsis survey: a study of doctors' knowledge and perception about sepsis. Crit Care, 8, R409-13 (2004)
    • (2004) Crit Care , vol.8
    • Poeze, M.1    Ramsay, G.2    Gerlach, H.3    Rubulotta, F.4    Levy, M.5
  • 3
    • 11344279695 scopus 로고    scopus 로고
    • Bench-to-bedside review: Sepsis is a disease of the microcirculation
    • Spronk, P. E., D. F. Zandstra & C. Ince: Bench-to-bedside review: sepsis is a disease of the microcirculation. Crit Care, 8, 462-8 (2004)
    • (2004) Crit Care , vol.8 , pp. 462-468
    • Spronk, P.E.1    Zandstra, D.F.2    Ince, C.3
  • 4
    • 1642602647 scopus 로고    scopus 로고
    • Lipid unites disparate syndromes of sepsis
    • Wang, H., C. J. Czura & K. J. Tracey: Lipid unites disparate syndromes of sepsis. Nat Med, 10, 124-5 (2004)
    • (2004) Nat Med , vol.10 , pp. 124-125
    • Wang, H.1    Czura, C.J.2    Tracey, K.J.3
  • 5
    • 0038578608 scopus 로고    scopus 로고
    • Novel strategies for the treatment of sepsis
    • Riedemann, N. C., R. F. Guo & P. A. Ward: Novel strategies for the treatment of sepsis. Nat Med, 9, 517-24 (2003)
    • (2003) Nat Med , vol.9 , pp. 517-524
    • Riedemann, N.C.1    Guo, R.F.2    Ward, P.A.3
  • 6
    • 21344439005 scopus 로고
    • Effects of Adrenotropic Drugs on the Release of Histamine in the Anaphylactic Reaction of the Isolated Guinea Pig Heart
    • Mannaioni, P. F., L. Zilletti, A. Guidotti & A. Giotti: Effects of Adrenotropic Drugs on the Release of Histamine in the Anaphylactic Reaction of the Isolated Guinea Pig Heart. Life Sci, 11, 347-50 (1964)
    • (1964) Life Sci , vol.11 , pp. 347-350
    • Mannaioni, P.F.1    Zilletti, L.2    Guidotti, A.3    Giotti, A.4
  • 7
    • 0033638849 scopus 로고    scopus 로고
    • The sympathetic nerve - An integrative interface between two supersystems: The brain and the immune system
    • Elenkov, I. J., R. L. Wilder, G. P. Chrousos & E. S. Vizi: The sympathetic nerve - an integrative interface between two supersystems: the brain and the immune system. Pharmacol Rev, 52, 595-638 (2000)
    • (2000) Pharmacol Rev , vol.52 , pp. 595-638
    • Elenkov, I.J.1    Wilder, R.L.2    Chrousos, G.P.3    Vizi, E.S.4
  • 8
    • 0036010814 scopus 로고    scopus 로고
    • Nonsynaptic noradrenaline release in neuro-immune responses
    • Vizi, E. S. & I. J. Elenkov: Nonsynaptic noradrenaline release in neuro-immune responses. Acta Biol Hung, 53, 229-44 (2002)
    • (2002) Acta Biol Hung , vol.53 , pp. 229-244
    • Vizi, E.S.1    Elenkov, I.J.2
  • 11
    • 0037180778 scopus 로고    scopus 로고
    • The inflammatory reflex
    • Tracey, K. J.: The inflammatory reflex. Nature, 420, 853-9 (2002)
    • (2002) Nature , vol.420 , pp. 853-859
    • Tracey, K.J.1
  • 12
    • 0035177937 scopus 로고    scopus 로고
    • Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis
    • Echtenacher, B., M. A. Freudenberg, R. S. Jack & D. N. Mannel: Differences in innate defense mechanisms in endotoxemia and polymicrobial septic peritonitis. Infect Immun, 69, 7271-6 (2001)
    • (2001) Infect Immun , vol.69 , pp. 7271-7276
    • Echtenacher, B.1    Freudenberg, M.A.2    Jack, R.S.3    Mannel, D.N.4
  • 14
    • 0029822874 scopus 로고    scopus 로고
    • Pentoxifylline maintains vascular endothelial cell function during hyperdynamic and hypodynamic sepsis
    • Wang, P., T. J. Wood, Z. F. Ba & I. H. Chaudry: Pentoxifylline maintains vascular endothelial cell function during hyperdynamic and hypodynamic sepsis. Surgery, 120, 367-73 (1996)
    • (1996) Surgery , vol.120 , pp. 367-373
    • Wang, P.1    Wood, T.J.2    Ba, Z.F.3    Chaudry, I.H.4
  • 15
    • 0034112615 scopus 로고    scopus 로고
    • Immunologic response to infection and its role in septic shock
    • Casey, L. C.: Immunologic response to infection and its role in septic shock. Crit Care Clin, 16, 193-213 (2000)
    • (2000) Crit Care Clin , vol.16 , pp. 193-213
    • Casey, L.C.1
  • 16
    • 0030908902 scopus 로고    scopus 로고
    • High mobility group 1 protein is not stably associated with the chromosomes of somatic cells
    • Falciola, L., F. Spada, S. Calogero, G. Langst, R. Voit, I. Grummt & M. E. Bianchi: High mobility group 1 protein is not stably associated with the chromosomes of somatic cells. J Cell Biol, 137, 19-26 (1997)
    • (1997) J Cell Biol , vol.137 , pp. 19-26
    • Falciola, L.1    Spada, F.2    Calogero, S.3    Langst, G.4    Voit, R.5    Grummt, I.6    Bianchi, M.E.7
  • 20
    • 0031045654 scopus 로고    scopus 로고
    • Passive immunization against tumor necrosis factor-alpha impairs host defense during pneumococcal pneumonia in mice
    • van der Poll, T., C. V. Keogh, W. A. Buurman & S. F. Lowry: Passive immunization against tumor necrosis factor-alpha impairs host defense during pneumococcal pneumonia in mice. Am J Respir Crit Care Med, 155, 603-8 (1997)
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 603-608
    • Van Der Poll, T.1    Keogh, C.V.2    Buurman, W.A.3    Lowry, S.F.4
  • 21
    • 2142726023 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: Increased mortality in the absence of liver injury
    • Moore, T. A., H. Y. Lau, A. L. Cogen, C. L. Monteleon & T. J. Standiford: Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. Shock, 20, 309-15 (2003)
    • (2003) Shock , vol.20 , pp. 309-315
    • Moore, T.A.1    Lau, H.Y.2    Cogen, A.L.3    Monteleon, C.L.4    Standiford, T.J.5
  • 23
    • 0027420579 scopus 로고
    • Tumor necrosis factor: An updated review of its biology
    • Tracey, K. J. & A. Cerami: Tumor necrosis factor: an updated review of its biology. Crit Care Med, 21, S415-22 (1993)
    • (1993) Crit Care Med , vol.21
    • Tracey, K.J.1    Cerami, A.2
  • 26
    • 0017108927 scopus 로고
    • On the mechanism of activation of the hypothalamo-pituitary-adrenal reaction to changes in the environment (the 'alarm reaction')
    • Laborit, H.: On the mechanism of activation of the hypothalamo-pituitary- adrenal reaction to changes in the environment (the 'alarm reaction'). Resuscitation, 5, 19-30 (1976)
    • (1976) Resuscitation , vol.5 , pp. 19-30
    • Laborit, H.1
  • 27
    • 0000668139 scopus 로고
    • Thymus and adrenals in the response of the organism to injuries and intoxications
    • Seyle, H.: Thymus and adrenals in the response of the organism to injuries and intoxications. Br J Exp Pathol, 17, 234-238 (1936)
    • (1936) Br J Exp Pathol , vol.17 , pp. 234-238
    • Seyle, H.1
  • 28
    • 0022530255 scopus 로고
    • Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
    • Besedovsky, H., A. del Rey, E. Sorkin & C. A. Dinarello: Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science, 233, 652-4 (1986)
    • (1986) Science , vol.233 , pp. 652-654
    • Besedovsky, H.1    Del Rey, A.2    Sorkin, E.3    Dinarello, C.A.4
  • 29
    • 0036229599 scopus 로고    scopus 로고
    • Regulation mechanisms of intestinal secretion: Implications in nutrient absorption
    • Wapnir, R. A. & S. Teichberg: Regulation mechanisms of intestinal secretion: implications in nutrient absorption. J Nutr Biochem, 13, 190-199 (2002)
    • (2002) J Nutr Biochem , vol.13 , pp. 190-199
    • Wapnir, R.A.1    Teichberg, S.2
  • 30
    • 0023889666 scopus 로고
    • Interleukin-1 immunoreactive innervation of the human hypothalamus
    • Breder, C. D., C. A. Dinarello & C. B. Saper: Interleukin-1 immunoreactive innervation of the human hypothalamus. Science, 240, 321-4 (1988)
    • (1988) Science , vol.240 , pp. 321-324
    • Breder, C.D.1    Dinarello, C.A.2    Saper, C.B.3
  • 31
    • 0031868405 scopus 로고    scopus 로고
    • Vagal and splanchnic afferents are not necessary for the anorexia produced by peripheral IL-1beta, LPS, and MDP
    • Porter, M. H., B. J. Hrupka, W. Langhans & G. J. Schwartz: Vagal and splanchnic afferents are not necessary for the anorexia produced by peripheral IL-1beta, LPS, and MDP. Am J Physiol, 275, R384-9 (1998)
    • (1998) Am J Physiol , vol.275
    • Porter, M.H.1    Hrupka, B.J.2    Langhans, W.3    Schwartz, G.J.4
  • 32
    • 2942687605 scopus 로고    scopus 로고
    • Elaborate interactions between the immune and nervous systems
    • Steinman, L.: Elaborate interactions between the immune and nervous systems. Nat Immunol, 5, 575-81 (2004)
    • (2004) Nat Immunol , vol.5 , pp. 575-581
    • Steinman, L.1
  • 33
    • 0024539186 scopus 로고
    • Pharmacological characterization of neuropeptide Y and noradrenaline mechanisms in sympathetic control of pig spleen
    • Lundberg, J. M., A. Rudehill & A. Sollevi: Pharmacological characterization of neuropeptide Y and noradrenaline mechanisms in sympathetic control of pig spleen. Eur J Pharmacol, 163, 103-13 (1989)
    • (1989) Eur J Pharmacol , vol.163 , pp. 103-113
    • Lundberg, J.M.1    Rudehill, A.2    Sollevi, A.3
  • 34
    • 0037201295 scopus 로고    scopus 로고
    • Immunomodulatory effects of vasoactive catecholamines
    • Bergmann, M. & T. Sautner: Immunomodulatory effects of vasoactive catecholamines. Wien Klin Wochenschr, 114, 752-61 (2002)
    • (2002) Wien Klin Wochenschr , vol.114 , pp. 752-761
    • Bergmann, M.1    Sautner, T.2
  • 35
    • 3242790884 scopus 로고    scopus 로고
    • Increased gut-derived norepinephrine release in sepsis: Up-regulation of intestinal tyrosine hydroxylase
    • Zhou, M., H. Hank Simms & P. Wang: Increased gut-derived norepinephrine release in sepsis: up-regulation of intestinal tyrosine hydroxylase. Biochim Biophys Acta, 1689, 212-8 (2004)
    • (2004) Biochim Biophys Acta , vol.1689 , pp. 212-218
    • Zhou, M.1    Hank Simms, H.2    Wang, P.3
  • 36
    • 0029382098 scopus 로고
    • Sustained elevation in circulating catecholamine levels during polymicrobial sepsis
    • Hahn, P. Y., P. Wang, S. M. Tait, Z. F. Ba, S. S. Reich & I. H. Chaudry: Sustained elevation in circulating catecholamine levels during polymicrobial sepsis. Shock, 4, 269-73 (1995)
    • (1995) Shock , vol.4 , pp. 269-273
    • Hahn, P.Y.1    Wang, P.2    Tait, S.M.3    Ba, Z.F.4    Reich, S.S.5    Chaudry, I.H.6
  • 37
    • 0033635547 scopus 로고    scopus 로고
    • Gut-derived norepinephrine plays a critical role in producing hepatocellular dysfunction during early sepsis
    • Yang, S., D. J. Koo, M. Zhou, I. H. Chaudry & P. Wang: Gut-derived norepinephrine plays a critical role in producing hepatocellular dysfunction during early sepsis. Am J Physiol Gastrointest Liver Physiol, 279, G1274-81 (2000)
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Yang, S.1    Koo, D.J.2    Zhou, M.3    Chaudry, I.H.4    Wang, P.5
  • 38
    • 0036658760 scopus 로고    scopus 로고
    • Rate and extent of phagocytosis in macrophages lacking vamp3
    • Allen, L.-A. H., C. Yang & J. E. Pessin: Rate and extent of phagocytosis in macrophages lacking vamp3. J Leukoc Biol, 72, 217-221 (2002)
    • (2002) J Leukoc Biol , vol.72 , pp. 217-221
    • Allen, L.-A.H.1    Yang, C.2    Pessin, J.E.3
  • 39
    • 0347786911 scopus 로고    scopus 로고
    • The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion
    • Pagan, J. K., F. G. Wylie, S. Joseph, C. Widberg, N. J. Bryant, D. E. James & J. L. Stow: The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion. Curr Biol, 13, 156-60 (2003)
    • (2003) Curr Biol , vol.13 , pp. 156-160
    • Pagan, J.K.1    Wylie, F.G.2    Joseph, S.3    Widberg, C.4    Bryant, N.J.5    James, D.E.6    Stow, J.L.7
  • 40
    • 0033659365 scopus 로고    scopus 로고
    • Syntaxin 11 is an atypical SNARE abundant in the immune system
    • Prekeris, R., J. Klumperman & R. H. Scheller: Syntaxin 11 is an atypical SNARE abundant in the immune system. Eur J Cell Biol, 79, 771-80 (2000)
    • (2000) Eur J Cell Biol , vol.79 , pp. 771-780
    • Prekeris, R.1    Klumperman, J.2    Scheller, R.H.3
  • 42
    • 0029949540 scopus 로고    scopus 로고
    • Characterization and subcellular localization of target membrane soluble NSF attachment protein receptors (t-SNAREs) in macrophages. Syntaxins 2, 3, and 4 are present on phagosomal membranes
    • Hackam, D. J., O. D. Rotstein, M. K. Bennett, A. Klip, S. Grinstein & M. F. Manolson: Characterization and subcellular localization of target membrane soluble NSF attachment protein receptors (t-SNAREs) in macrophages. Syntaxins 2, 3, and 4 are present on phagosomal membranes. J Immunol, 156, 4377-83 (1996)
    • (1996) J Immunol , vol.156 , pp. 4377-4383
    • Hackam, D.J.1    Rotstein, O.D.2    Bennett, M.K.3    Klip, A.4    Grinstein, S.5    Manolson, M.F.6
  • 43
    • 0028980924 scopus 로고
    • Involvement of HPC-1/syntaxin-1A antigen in transmitter release from PC12h cells
    • Kushima, Y., T. Fujiwara, T. Morimoto & K. Akagawa: Involvement of HPC-1/syntaxin-1A antigen in transmitter release from PC12h cells. Biochem Biophys Res Commun, 212, 97-103 (1995)
    • (1995) Biochem Biophys Res Commun , vol.212 , pp. 97-103
    • Kushima, Y.1    Fujiwara, T.2    Morimoto, T.3    Akagawa, K.4
  • 44
    • 0034093307 scopus 로고    scopus 로고
    • A late phase of exocytosis from synaptosomes induced by elevated [Ca2+]i is not blocked by Clostridial neurotoxins
    • Ashton, A. C. & J. O. Dolly: A late phase of exocytosis from synaptosomes induced by elevated [Ca2+]i is not blocked by Clostridial neurotoxins. J Neurochem, 74, 1979-88 (2000)
    • (2000) J Neurochem , vol.74 , pp. 1979-1988
    • Ashton, A.C.1    Dolly, J.O.2
  • 45
    • 0141816760 scopus 로고    scopus 로고
    • Differential expression of syntaxin 1A and 1B by noradrenergic and adrenergic chromaffin cells
    • Baltazar, G., A. P. Carvalho & E. P. Duarte: Differential expression of syntaxin 1A and 1B by noradrenergic and adrenergic chromaffin cells. Neurochem Res, 28, 1453-7 (2003)
    • (2003) Neurochem Res , vol.28 , pp. 1453-1457
    • Baltazar, G.1    Carvalho, A.P.2    Duarte, E.P.3
  • 46
    • 0037335481 scopus 로고    scopus 로고
    • A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity
    • Sung, U., S. Apparsundaram, A. Galli, K. M. Kahlig, V. Savchenko, S. Schroeter, M. W. Quick & R. D. Blakely: A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity. J Neurosci, 23, 1697-709 (2003)
    • (2003) J Neurosci , vol.23 , pp. 1697-1709
    • Sung, U.1    Apparsundaram, S.2    Galli, A.3    Kahlig, K.M.4    Savchenko, V.5    Schroeter, S.6    Quick, M.W.7    Blakely, R.D.8
  • 47
    • 0037008753 scopus 로고    scopus 로고
    • Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly
    • Scales, S. J., B. A. Hesser, E. S. Masuda & R. H. Scheller: Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly. J Biol Chem, 277, 28271-9 (2002)
    • (2002) J Biol Chem , vol.277 , pp. 28271-28279
    • Scales, S.J.1    Hesser, B.A.2    Masuda, E.S.3    Scheller, R.H.4
  • 48
    • 0032852641 scopus 로고    scopus 로고
    • Neurotransmitter transporters in the central nervous system
    • Masson, J., C. Sagne, M. Hamon & S. El Mestikawy: Neurotransmitter transporters in the central nervous system. Pharmacol Rev, 51, 439-64 (1999)
    • (1999) Pharmacol Rev , vol.51 , pp. 439-464
    • Masson, J.1    Sagne, C.2    Hamon, M.3    El Mestikawy, S.4
  • 49
    • 0034786538 scopus 로고    scopus 로고
    • Norepinephrine-induced hepatocellular dysfunction in early sepsis is mediated by activation of alpha2-adrenoceptors
    • Yang, S., M. Zhou, I. H. Chaudry & P. Wang: Norepinephrine-induced hepatocellular dysfunction in early sepsis is mediated by activation of alpha2-adrenoceptors. Am J Physiol Gastrointest Liver Physiol, 281, G1014-21 (2001)
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Yang, S.1    Zhou, M.2    Chaudry, I.H.3    Wang, P.4
  • 50
    • 0035958703 scopus 로고    scopus 로고
    • The role of Kupffer cell alpha (2)-adrenoceptors in norepinephrine- induced TNF-alpha production
    • Zhou, M., S. Yang, D. J. Koo, D. A. Oman, I. H. Chaudry & P. Wang: The role of Kupffer cell alpha (2)-adrenoceptors in norepinephrine-induced TNF-alpha production. Biochim Biophys Acta, 1537, 49-57 (2001)
    • (2001) Biochim Biophys Acta , vol.1537 , pp. 49-57
    • Zhou, M.1    Yang, S.2    Koo, D.J.3    Oman, D.A.4    Chaudry, I.H.5    Wang, P.6
  • 51
    • 20444403005 scopus 로고    scopus 로고
    • Gut-derived Norepinephrine plays an important role in upregulating IL-1β and IL-10
    • In Pess
    • Zhou, M., P. Das, H. H. Simms & P. Wang: Gut-derived Norepinephrine plays an important role in upregulating IL-1β and IL-10 (In Pess). BBA (2005)
    • (2005) BBA
    • Zhou, M.1    Das, P.2    Simms, H.H.3    Wang, P.4
  • 52
    • 0025070946 scopus 로고
    • Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor
    • Spengler, R. N., R. M. Allen, D. G. Remick, R. M. Strieter & S. L. Kunkel: Stimulation of alpha-adrenergic receptor augments the production of macrophage-derived tumor necrosis factor. J Immunol, 145, 1430-4 (1990)
    • (1990) J Immunol , vol.145 , pp. 1430-1434
    • Spengler, R.N.1    Allen, R.M.2    Remick, D.G.3    Strieter, R.M.4    Kunkel, S.L.5
  • 53
    • 0026100451 scopus 로고
    • The effect of norepinephrine on endotoxin-mediated macrophage activation
    • Hu, X. X., E. A. Goldmuntz & C. F. Brosnan: The effect of norepinephrine on endotoxin-mediated macrophage activation. J Neuroimmunol, 31, 35-42 (1991)
    • (1991) J Neuroimmunol , vol.31 , pp. 35-42
    • Hu, X.X.1    Goldmuntz, E.A.2    Brosnan, C.F.3
  • 54
    • 0036196908 scopus 로고    scopus 로고
    • Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis
    • Miller, L. E., J. Grifka, J. Scholmerich & R. H. Straub: Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis. J Rheumatol, 29, 427-35 (2002)
    • (2002) J Rheumatol , vol.29 , pp. 427-435
    • Miller, L.E.1    Grifka, J.2    Scholmerich, J.3    Straub, R.H.4
  • 55
    • 0030227883 scopus 로고    scopus 로고
    • Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: Clinical implications
    • Elenkov, I. J., D. A. Papanicolaou, R. L. Wilder & G. P. Chrousos: Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc Assoc Am Physicians, 108, 374-81 (1996)
    • (1996) Proc Assoc Am Physicians , vol.108 , pp. 374-381
    • Elenkov, I.J.1    Papanicolaou, D.A.2    Wilder, R.L.3    Chrousos, G.P.4
  • 56
    • 0032146334 scopus 로고    scopus 로고
    • Stimulation of beta-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice
    • Hasko, G., C. Szabo, Z. H. Nemeth, A. L. Salzman & E. S. Vizi: Stimulation of beta-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice. J Neuroimmunol, 88, 57-61 (1998)
    • (1998) J Neuroimmunol , vol.88 , pp. 57-61
    • Hasko, G.1    Szabo, C.2    Nemeth, Z.H.3    Salzman, A.L.4    Vizi, E.S.5
  • 57
    • 0026594462 scopus 로고
    • Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists
    • Severn, A., N. T. Rapson, C. A. Hunter & F. Y. Liew: Regulation of tumor necrosis factor production by adrenaline and beta-adrenergic agonists. J Immunol, 148, 3441-5 (1992)
    • (1992) J Immunol , vol.148 , pp. 3441-3445
    • Severn, A.1    Rapson, N.T.2    Hunter, C.A.3    Liew, F.Y.4
  • 58
    • 20444405887 scopus 로고    scopus 로고
    • 2A-adrenoceptor (AR) plays an important role in TNF-α release in sepsis
    • 2A-adrenoceptor (AR) plays an important role in TNF-α release in sepsis. Shock, 21, 30 (2004)
    • (2004) Shock , vol.21 , pp. 30
    • Das, P.1    Zhou, M.2    Goyert, S.M.3    Simms, H.H.4    Wang, P.5
  • 59
    • 21344450239 scopus 로고    scopus 로고
    • A novel approach to inhibit inflammatory responses in sepsis: Modulation of the sympathetic nervous system
    • in press
    • Das, P., R. Wu, W. Dong, D. Yang & P. Wang: A novel approach to inhibit inflammatory responses in sepsis: modulation of the sympathetic nervous system (in press). Shock (2005)
    • (2005) Shock
    • Das, P.1    Wu, R.2    Dong, W.3    Yang, D.4    Wang, P.5
  • 60
    • 1542613795 scopus 로고    scopus 로고
    • Dual mode of catecholamine action on splenic macrophage phagocytosis in wall lizard, Hemidactylus flaviviridis
    • Roy, B. & U. Rai: Dual mode of catecholamine action on splenic macrophage phagocytosis in wall lizard, Hemidactylus flaviviridis. Gen Comp Endocrinol, 136, 180-91 (2004)
    • (2004) Gen Comp Endocrinol , vol.136 , pp. 180-191
    • Roy, B.1    Rai, U.2
  • 61
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., H. Hosoda, Y. Date, M. Nakazato, H. Matsuo & K. Kangawa: Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature, 402, 656-60 (1999)
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 63
    • 1642354552 scopus 로고    scopus 로고
    • Ghrelin: Integrative neuroendocrine peptide in health and disease
    • Wu, J. T. & J. G. Kral: Ghrelin: integrative neuroendocrine peptide in health and disease. Ann Surg, 239, 464-74 (2004)
    • (2004) Ann Surg , vol.239 , pp. 464-474
    • Wu, J.T.1    Kral, J.G.2
  • 64
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • van der Lely, A. J., M. Tschop, M. L. Heiman & E. Ghigo: Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocr Rev, 25, 426-57 (2004)
    • (2004) Endocr Rev , vol.25 , pp. 426-457
    • Van Der Lely, A.J.1    Tschop, M.2    Heiman, M.L.3    Ghigo, E.4
  • 65
    • 2542453815 scopus 로고    scopus 로고
    • Ghrelin - Satisfying a hunger for the mechanism
    • Cowley, M. A. & K. L. Grove: Ghrelin - satisfying a hunger for the mechanism. Endocrinology, 145, 2604-6 (2004)
    • (2004) Endocrinology , vol.145 , pp. 2604-2606
    • Cowley, M.A.1    Grove, K.L.2
  • 66
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop, M., D. L. Smiley & M. L. Heiman: Ghrelin induces adiposity in rodents. Nature, 407, 908-13 (2000)
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 67
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date, Y., M. Kojima, H. Hosoda, A. Sawaguchi, M. S. Mondal, T. Suganuma, S. Matsukura, K. Kangawa & M. Nakazato: Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology, 141, 4255-61 (2000)
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3    Sawaguchi, A.4    Mondal, M.S.5    Suganuma, T.6    Matsukura, S.7    Kangawa, K.8    Nakazato, M.9
  • 69
    • 0033784980 scopus 로고    scopus 로고
    • Systemic administration of ghrelin induces Fos and Egr-1 proteins in the hypothalamic arcuate nucleus of fasted and fed rats
    • Hewson, A. K. & S. L. Dickson: Systemic administration of ghrelin induces Fos and Egr-1 proteins in the hypothalamic arcuate nucleus of fasted and fed rats. J Neuroendocrinol, 12, 1047-9 (2000)
    • (2000) J Neuroendocrinol , vol.12 , pp. 1047-1049
    • Hewson, A.K.1    Dickson, S.L.2
  • 70
    • 0036842016 scopus 로고    scopus 로고
    • Central ghrelin modulates sympathetic activity in conscious rabbits
    • Matsumura, K., T. Tsuchihashi, K. Fujii, I. Abe & M. Iida: Central ghrelin modulates sympathetic activity in conscious rabbits. Hypertension, 40, 694-9 (2002)
    • (2002) Hypertension , vol.40 , pp. 694-699
    • Matsumura, K.1    Tsuchihashi, T.2    Fujii, K.3    Abe, I.4    Iida, M.5
  • 72
    • 2342620868 scopus 로고    scopus 로고
    • Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats
    • Lin, Y., K. Matsumura, M. Fukuhara, S. Kagiyama, K. Fujii & M. Iida: Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats. Hypertension, 43, 977-82 (2004)
    • (2004) Hypertension , vol.43 , pp. 977-982
    • Lin, Y.1    Matsumura, K.2    Fukuhara, M.3    Kagiyama, S.4    Fujii, K.5    Iida, M.6
  • 73
    • 0142089853 scopus 로고    scopus 로고
    • Centrally administered ghrelin suppresses sympathetic nerve activity in brown adipose tissue of rats
    • Yasuda, T., T. Masaki, T. Kakuma & H. Yoshimatsu: Centrally administered ghrelin suppresses sympathetic nerve activity in brown adipose tissue of rats. Neurosci Lett, 349, 75-8 (2003)
    • (2003) Neurosci Lett , vol.349 , pp. 75-78
    • Yasuda, T.1    Masaki, T.2    Kakuma, T.3    Yoshimatsu, H.4
  • 74
    • 20844460120 scopus 로고    scopus 로고
    • Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
    • Nagaya, N., J. Moriya, Y. Yasumura, M. Uematsu, F. Ono, W. Shimizu, K. Ueno, M. Kitakaze, K. Miyatake & K. Kangawa: Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation, 110, 3674-9 (2004)
    • (2004) Circulation , vol.110 , pp. 3674-3679
    • Nagaya, N.1    Moriya, J.2    Yasumura, Y.3    Uematsu, M.4    Ono, F.5    Shimizu, W.6    Ueno, K.7    Kitakaze, M.8    Miyatake, K.9    Kangawa, K.10
  • 75
    • 4143111272 scopus 로고    scopus 로고
    • Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis
    • Wu, R., M. Zhou, X. Cui, H. H. Simms & P. Wang: Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis. Am J Physiol Heart Circ Physiol, 287, H1296-302 (2004)
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Wu, R.1    Zhou, M.2    Cui, X.3    Simms, H.H.4    Wang, P.5
  • 76
    • 0344394263 scopus 로고    scopus 로고
    • Alterations of plasma ghrelin levels in rats with lipopolysaccharide- induced wasting syndrome and effects of ghrelin treatment on the syndrome
    • Hataya, Y., T. Akamizu, H. Hosoda, N. Kanamoto, K. Moriyama, K. Kangawa, K. Takaya & K. Nakao: Alterations of plasma ghrelin levels in rats with lipopolysaccharide-induced wasting syndrome and effects of ghrelin treatment on the syndrome. Endocrinology, 144, 5365-71 (2003)
    • (2003) Endocrinology , vol.144 , pp. 5365-5371
    • Hataya, Y.1    Akamizu, T.2    Hosoda, H.3    Kanamoto, N.4    Moriyama, K.5    Kangawa, K.6    Takaya, K.7    Nakao, K.8
  • 77
    • 0038054817 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide shifts fasted plasma ghrelin to postprandial levels in rats
    • Basa, N. R., L. Wang, J. R. Arteaga, D. Heber, E. H. Livingston & Y. Tache: Bacterial lipopolysaccharide shifts fasted plasma ghrelin to postprandial levels in rats. Neurosci Lett, 343, 25-8 (2003)
    • (2003) Neurosci Lett , vol.343 , pp. 25-28
    • Basa, N.R.1    Wang, L.2    Arteaga, J.R.3    Heber, D.4    Livingston, E.H.5    Tache, Y.6
  • 78
    • 21344441622 scopus 로고    scopus 로고
    • Ghrelin downregulates TNF-alpha in sepsis via the activation of the vagus nerve
    • in press
    • Wu, R., W. Dong, H. Simms & P. Wang: Ghrelin downregulates TNF-alpha in sepsis via the activation of the vagus nerve. Surg Infect, (in press), (2005)
    • (2005) Surg Infect
    • Wu, R.1    Dong, W.2    Simms, H.3    Wang, P.4
  • 79
    • 0242660829 scopus 로고    scopus 로고
    • Neuropeptide Y: A physiological orexigen modulated by the feedback action of ghrelin and leptin
    • Kalra, S. P. & P. S. Kalra: Neuropeptide Y: a physiological orexigen modulated by the feedback action of ghrelin and leptin. Endocrine, 22, 49-56 (2003)
    • (2003) Endocrine , vol.22 , pp. 49-56
    • Kalra, S.P.1    Kalra, P.S.2
  • 80
    • 0942298220 scopus 로고    scopus 로고
    • Melanocortin receptors mediate the excitatory effects of blood-borne murine leptin on hypothalamic paraventricular neurons in rat
    • Zhang, Z. H. & R. B. Felder: Melanocortin receptors mediate the excitatory effects of blood-borne murine leptin on hypothalamic paraventricular neurons in rat. Am J Physiol Regul Integr Comp Physiol, 286, R303-10 (2004)
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Zhang, Z.H.1    Felder, R.B.2
  • 81
    • 0242637573 scopus 로고    scopus 로고
    • Alteration of NMDA NR1 receptors within the paraventricular nucleus of hypothalamus in rats with heart failure
    • Li, Y. F., K. G. Cornish & K. P. Patel: Alteration of NMDA NR1 receptors within the paraventricular nucleus of hypothalamus in rats with heart failure. Circ Res, 93, 990-7 (2003)
    • (2003) Circ Res , vol.93 , pp. 990-997
    • Li, Y.F.1    Cornish, K.G.2    Patel, K.P.3
  • 82
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin, J. P. & R. Duvoisin: The metabotropic glutamate receptors: structure and functions. Neuropharmacology, 34, 1-26 (1995)
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 83
    • 0141893612 scopus 로고    scopus 로고
    • Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors
    • Chen, Q. H., J. R. Haywood & G. M. Toney: Sympathoexcitation by PVN-injected bicuculline requires activation of excitatory amino acid receptors. Hypertension, 42, 725-31 (2003)
    • (2003) Hypertension , vol.42 , pp. 725-731
    • Chen, Q.H.1    Haywood, J.R.2    Toney, G.M.3
  • 84
    • 4444370704 scopus 로고    scopus 로고
    • Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver
    • Kalsbeek, A., S. La Fleur, C. Van Heijningen & R. M. Buijs: Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver. J Neurosci, 24, 7604-13 (2004)
    • (2004) J Neurosci , vol.24 , pp. 7604-7613
    • Kalsbeek, A.1    La Fleur, S.2    Van Heijningen, C.3    Buijs, R.M.4
  • 85
    • 0038748471 scopus 로고    scopus 로고
    • Septic encephalopathy. Diagnosis und therapy
    • Eggers, V., A. Schilling, W. J. Kox & C. Spies: [Septic encephalopathy. Diagnosis und therapy]. Anaesthesist, 52, 294-303 (2003)
    • (2003) Anaesthesist , vol.52 , pp. 294-303
    • Eggers, V.1    Schilling, A.2    Kox, W.J.3    Spies, C.4
  • 86
    • 0038681852 scopus 로고    scopus 로고
    • Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy
    • Ahboucha, S., P. Desjardins, N. Chatauret, G. Pomier-Layrargues & R. F. Butterworth: Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy. Neurochem Int, 43, 551-6 (2003)
    • (2003) Neurochem Int , vol.43 , pp. 551-556
    • Ahboucha, S.1    Desjardins, P.2    Chatauret, N.3    Pomier-Layrargues, G.4    Butterworth, R.F.5
  • 87
    • 0030058595 scopus 로고    scopus 로고
    • An alteration in the gamma-aminobutyric acid receptor system in experimentally induced septic shock in rats
    • Kadoi, Y. & S. Saito: An alteration in the gamma-aminobutyric acid receptor system in experimentally induced septic shock in rats. Crit Care Med, 24, 298-305 (1996)
    • (1996) Crit Care Med , vol.24 , pp. 298-305
    • Kadoi, Y.1    Saito, S.2
  • 88
    • 0028884702 scopus 로고
    • Augmented sensitivity to benzodiazepine in septic shock rats
    • Komatsubara, T., Y. Kadoi & S. Saito: Augmented sensitivity to benzodiazepine in septic shock rats. Can J Anaesth, 42, 937-43 (1995)
    • (1995) Can J Anaesth , vol.42 , pp. 937-943
    • Komatsubara, T.1    Kadoi, Y.2    Saito, S.3
  • 89
    • 0014668762 scopus 로고
    • Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
    • Olney, J. W.: Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science, 164, 719-21 (1969)
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 90
    • 0042886941 scopus 로고    scopus 로고
    • Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation
    • Prass, K., C. Meisel, C. Hoflich, J. Braun, E. Halle, T. Wolf, K. Ruscher, I. V. Victorov, J. Priller, U. Dirnagl, H. D. Volk & A. Meisel: Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med, 198, 725-36 (2003)
    • (2003) J Exp Med , vol.198 , pp. 725-736
    • Prass, K.1    Meisel, C.2    Hoflich, C.3    Braun, J.4    Halle, E.5    Wolf, T.6    Ruscher, K.7    Victorov, I.V.8    Priller, J.9    Dirnagl, U.10    Volk, H.D.11    Meisel, A.12
  • 91
    • 0036835441 scopus 로고    scopus 로고
    • Growth stimulation of intestinal commensal Escherichia coli by catecholamines: A possible contributory factor in trauma-induced sepsis
    • Freestone, P. P., P. H. Williams, R. D. Haigh, A. F. Maggs, C. P. Neal & M. Lyte: Growth stimulation of intestinal commensal Escherichia coli by catecholamines: a possible contributory factor in trauma-induced sepsis. Shock, 18, 465-70 (2002)
    • (2002) Shock , vol.18 , pp. 465-470
    • Freestone, P.P.1    Williams, P.H.2    Haigh, R.D.3    Maggs, A.F.4    Neal, C.P.5    Lyte, M.6
  • 92
    • 0037431758 scopus 로고    scopus 로고
    • Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes
    • Lyte, M., P. P. Freestone, C. P. Neal, B. A. Olson, R. D. Haigh, R. Bayston & P. H. Williams: Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes. Lancet, 361, 130-5 (2003)
    • (2003) Lancet , vol.361 , pp. 130-135
    • Lyte, M.1    Freestone, P.P.2    Neal, C.P.3    Olson, B.A.4    Haigh, R.D.5    Bayston, R.6    Williams, P.H.7
  • 93
    • 0038129534 scopus 로고    scopus 로고
    • HPA axis activation and neurochemical responses to bacterial translocation from the gastrointestinal tract
    • Dunn, A. J., T. Ando, R. F. Brown & R. D. Berg: HPA axis activation and neurochemical responses to bacterial translocation from the gastrointestinal tract. Ann N Y Acad Sci, 992, 21-9 (2003)
    • (2003) Ann N Y Acad Sci , vol.992 , pp. 21-29
    • Dunn, A.J.1    Ando, T.2    Brown, R.F.3    Berg, R.D.4
  • 94
    • 0033814549 scopus 로고    scopus 로고
    • Gut-derived sepsis occurs when the right pathogen with the right virulence genes meets the right host: Evidence for in vivo virulence expression in Pseudomonas aeruginosa
    • Alverdy, J., C. Holbrook, F. Rocha, L. Seiden, R. L. Wu, M. Musch, E. Chang, D. Ohman & S. Suh: Gut-derived sepsis occurs when the right pathogen with the right virulence genes meets the right host: evidence for in vivo virulence expression in Pseudomonas aeruginosa. Ann Surg, 232, 480-9 (2000)
    • (2000) Ann Surg , vol.232 , pp. 480-489
    • Alverdy, J.1    Holbrook, C.2    Rocha, F.3    Seiden, L.4    Wu, R.L.5    Musch, M.6    Chang, E.7    Ohman, D.8    Suh, S.9


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