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Volumn 120, Issue 2, 2007, Pages 242-250

MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte-macrophage colony-stimulating factor production in macrophages

Author keywords

Cytokine; Macrophages; MAPK; MEKK3; TLR signalling

Indexed keywords

COMPLEMENTARY DNA; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B ALPHA; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 33845979829     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2006.02495.x     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 0036159842 scopus 로고    scopus 로고
    • Endotoxin tolerance. A review
    • West MA, Heagy W. Endotoxin tolerance. A review. Crit Care Med 2002: 30:S64-S73.
    • (2002) Crit Care Med , vol.30
    • West, M.A.1    Heagy, W.2
  • 2
    • 0037465251 scopus 로고    scopus 로고
    • The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
    • Dunne A, O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci STKE 2003: 2003: re3.
    • (2003) Sci STKE , vol.2003
    • Dunne, A.1    O'Neill, L.A.2
  • 4
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003: 85:85-95.
    • (2003) Immunol Lett , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 5
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001: 1:135-45.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 6
    • 0033975869 scopus 로고    scopus 로고
    • Innate immune recognition: Mechanisms and pathways
    • Medzhitov R, Janeway C Jr. Innate immune recognition: mechanisms and pathways. Immunol Rev 2000: 173:89-97.
    • (2000) Immunol Rev , vol.173 , pp. 89-97
    • Medzhitov, R.1    Janeway Jr., C.2
  • 7
    • 0035104961 scopus 로고    scopus 로고
    • Toll-like receptors: Their physiological role and signal transduction system
    • Takeuchi O, Akira S. Toll-like receptors: their physiological role and signal transduction system. Int Immunopharmacol 2001: 1:625-35.
    • (2001) Int Immunopharmacol , vol.1 , pp. 625-635
    • Takeuchi, O.1    Akira, S.2
  • 8
    • 0036448929 scopus 로고    scopus 로고
    • MyD88 as a bottle neck in Toll/IL-1 signaling
    • Takeuchi O, Akira S. MyD88 as a bottle neck in Toll/IL-1 signaling. Curr Top Microbiol Immunol 2002: 270:155-67.
    • (2002) Curr Top Microbiol Immunol , vol.270 , pp. 155-167
    • Takeuchi, O.1    Akira, S.2
  • 10
    • 0033580466 scopus 로고    scopus 로고
    • The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
    • Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 1999: 398:252-6.
    • (1999) Nature , vol.398 , pp. 252-256
    • Ninomiya-Tsuji, J.1    Kishimoto, K.2    Hiyama, A.3    Inoue, J.4    Cao, Z.5    Matsumoto, K.6
  • 12
    • 0033567388 scopus 로고    scopus 로고
    • ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
    • Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA, Ghosh S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev 1999: 13:2059-71.
    • (1999) Genes Dev , vol.13 , pp. 2059-2071
    • Kopp, E.1    Medzhitov, R.2    Carothers, J.3    Xiao, C.4    Douglas, I.5    Janeway, C.A.6    Ghosh, S.7
  • 13
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway
    • Lee FS, Hagler J, Chen ZJ, Maniatis T. Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell 1997: 88:213-22.
    • (1997) Cell , vol.88 , pp. 213-222
    • Lee, F.S.1    Hagler, J.2    Chen, Z.J.3    Maniatis, T.4
  • 14
    • 0033563101 scopus 로고    scopus 로고
    • Signaling by proinflammatory cytokines. Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
    • Baud V, Liu ZG, Bennett B, Suzuki N, Xia Y, Karin M. Signaling by proinflammatory cytokines. Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev 1999: 13:1297-308.
    • (1999) Genes Dev , vol.13 , pp. 1297-1308
    • Baud, V.1    Liu, Z.G.2    Bennett, B.3    Suzuki, N.4    Xia, Y.5    Karin, M.6
  • 15
    • 0033605575 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta
    • Zhao Q, Lee FS. Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta. J Biol Chem 1999: 274:8355-8.
    • (1999) J Biol Chem , vol.274 , pp. 8355-8358
    • Zhao, Q.1    Lee, F.S.2
  • 16
    • 0034922161 scopus 로고    scopus 로고
    • The essential role of MEKK3 in TNF-induced NF-kappaB activation
    • Yang J, Lin Y, Guo Z, et al. The essential role of MEKK3 in TNF-induced NF-kappaB activation. Nat Immunol 2001: 2:620-4.
    • (2001) Nat Immunol , vol.2 , pp. 620-624
    • Yang, J.1    Lin, Y.2    Guo, Z.3
  • 17
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
    • Malinin NL, Boldin MP, Kovalenko AV, Wallach D. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature 1997: 385:540-4.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 18
    • 17744371331 scopus 로고    scopus 로고
    • TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
    • Dumitru CD, Ceci JD, Tsatsanis C, et al. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 2000: 103:1071-83.
    • (2000) Cell , vol.103 , pp. 1071-1083
    • Dumitru, C.D.1    Ceci, J.D.2    Tsatsanis, C.3
  • 19
    • 0029913457 scopus 로고    scopus 로고
    • Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase
    • Blank JL, Gerwins P, Elliott EM, Sather S, Johnson GL. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. J Biol Chem 1996: 271:5361-8.
    • (1996) J Biol Chem , vol.271 , pp. 5361-5368
    • Blank, J.L.1    Gerwins, P.2    Elliott, E.M.3    Sather, S.4    Johnson, G.L.5
  • 20
    • 0035805552 scopus 로고    scopus 로고
    • MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression
    • Su B, Cheng J, Yang J, Guo Z. MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression. J Biol Chem 2001: 276:14784-90.
    • (2001) J Biol Chem , vol.276 , pp. 14784-14790
    • Su, B.1    Cheng, J.2    Yang, J.3    Guo, Z.4
  • 21
    • 0031036629 scopus 로고    scopus 로고
    • Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein kinase/ERK kinase kinase 3 (MEKK) derivative
    • Ellinger-Ziegelbauer H, Brown K, Kelly K, Siebenlist U. Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein kinase/ERK kinase kinase 3 (MEKK) derivative. J Biol Chem 1997: 272:2668-74.
    • (1997) J Biol Chem , vol.272 , pp. 2668-2674
    • Ellinger-Ziegelbauer, H.1    Brown, K.2    Kelly, K.3    Siebenlist, U.4
  • 22
    • 0030952084 scopus 로고    scopus 로고
    • Characterization of the mitogen-activated protein kinase kinase 4 (MKK4) /c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo
    • Deacon K, Blank JL. Characterization of the mitogen-activated protein kinase kinase 4 (MKK4) /c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo. J Biol Chem 1997: 272:14489-96.
    • (1997) J Biol Chem , vol.272 , pp. 14489-14496
    • Deacon, K.1    Blank, J.L.2
  • 23
    • 0033213597 scopus 로고    scopus 로고
    • Live cell fluorescence imaging of T cell MEKK2: Redistribution and activation in response to antigen stimulation of the T cell receptor
    • Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity 1999: 11:411-21.
    • (1999) Immunity , vol.11 , pp. 411-421
    • Schaefer, B.C.1    Ware, M.F.2    Marrack, P.3    Fanger, G.R.4    Kappler, J.W.5    Johnson, G.L.6    Monks, C.R.7
  • 24
    • 0034061264 scopus 로고    scopus 로고
    • Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation
    • Cheng J, Yang J, Xia Y, Karin M, Su B. Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol Cell Biol 2000: 20:2334-42.
    • (2000) Mol Cell Biol , vol.20 , pp. 2334-2342
    • Cheng, J.1    Yang, J.2    Xia, Y.3    Karin, M.4    Su, B.5
  • 25
    • 0034675925 scopus 로고    scopus 로고
    • MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells [In Process Citation]
    • Garrington TP, Ishizuka T, Papst PJ, et al.. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells [In Process Citation]. Embo J 2000: 19:5387-95.
    • (2000) Embo J , vol.19 , pp. 5387-5395
    • Garrington, T.P.1    Ishizuka, T.2    Papst, P.J.3
  • 26
    • 0346496017 scopus 로고    scopus 로고
    • Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
    • Huang Q, Yang J, Lin Y, Walker C, Cheng J, Liu ZG, Su B. Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3. Nat Immunol 2004: 5:98-103.
    • (2004) Nat Immunol , vol.5 , pp. 98-103
    • Huang, Q.1    Yang, J.2    Lin, Y.3    Walker, C.4    Cheng, J.5    Liu, Z.G.6    Su, B.7
  • 27
    • 0035875333 scopus 로고    scopus 로고
    • An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene
    • Myslinski E, Ame JC, Krol A, Carbon P. An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene. Nucl Acids Res 2001: 29:2502-9.
    • (2001) Nucl Acids Res , vol.29 , pp. 2502-2509
    • Myslinski, E.1    Ame, J.C.2    Krol, A.3    Carbon, P.4
  • 28
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA 2003: 100:183-8.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 30
    • 0028705684 scopus 로고
    • Generation of high-titer pseudotyped retroviral vectors with very broad host range
    • Yee JK, Friedmann T, Burns JC. Generation of high-titer pseudotyped retroviral vectors with very broad host range. Methods Cell Biol 1994: 43 Part A:99-112.
    • (1994) Methods Cell Biol , vol.43 , Issue.PART A , pp. 99-112
    • Yee, J.K.1    Friedmann, T.2    Burns, J.C.3
  • 31
    • 0035836668 scopus 로고    scopus 로고
    • Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
    • Chayama K, Papst PJ, Garrington TP, et al.. Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells. Proc Natl Acad Sci USA 2001: 98:4599-604.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4599-4604
    • Chayama, K.1    Papst, P.J.2    Garrington, T.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.