-
1
-
-
0036159842
-
Endotoxin tolerance. A review
-
West MA, Heagy W. Endotoxin tolerance. A review. Crit Care Med 2002: 30:S64-S73.
-
(2002)
Crit Care Med
, vol.30
-
-
West, M.A.1
Heagy, W.2
-
2
-
-
0037465251
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
Dunne A, O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci STKE 2003: 2003: re3.
-
(2003)
Sci STKE
, vol.2003
-
-
Dunne, A.1
O'Neill, L.A.2
-
4
-
-
0037460116
-
Recognition of pathogen-associated molecular patterns by TLR family
-
Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003: 85:85-95.
-
(2003)
Immunol Lett
, vol.85
, pp. 85-95
-
-
Akira, S.1
Hemmi, H.2
-
5
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001: 1:135-45.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 135-145
-
-
Medzhitov, R.1
-
6
-
-
0033975869
-
Innate immune recognition: Mechanisms and pathways
-
Medzhitov R, Janeway C Jr. Innate immune recognition: mechanisms and pathways. Immunol Rev 2000: 173:89-97.
-
(2000)
Immunol Rev
, vol.173
, pp. 89-97
-
-
Medzhitov, R.1
Janeway Jr., C.2
-
7
-
-
0035104961
-
Toll-like receptors: Their physiological role and signal transduction system
-
Takeuchi O, Akira S. Toll-like receptors: their physiological role and signal transduction system. Int Immunopharmacol 2001: 1:625-35.
-
(2001)
Int Immunopharmacol
, vol.1
, pp. 625-635
-
-
Takeuchi, O.1
Akira, S.2
-
8
-
-
0036448929
-
MyD88 as a bottle neck in Toll/IL-1 signaling
-
Takeuchi O, Akira S. MyD88 as a bottle neck in Toll/IL-1 signaling. Curr Top Microbiol Immunol 2002: 270:155-67.
-
(2002)
Curr Top Microbiol Immunol
, vol.270
, pp. 155-167
-
-
Takeuchi, O.1
Akira, S.2
-
10
-
-
0033580466
-
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 1999: 398:252-6.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
11
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 2001: 412:346-51.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
12
-
-
0033567388
-
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
-
Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA, Ghosh S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev 1999: 13:2059-71.
-
(1999)
Genes Dev
, vol.13
, pp. 2059-2071
-
-
Kopp, E.1
Medzhitov, R.2
Carothers, J.3
Xiao, C.4
Douglas, I.5
Janeway, C.A.6
Ghosh, S.7
-
13
-
-
0031285250
-
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway
-
Lee FS, Hagler J, Chen ZJ, Maniatis T. Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell 1997: 88:213-22.
-
(1997)
Cell
, vol.88
, pp. 213-222
-
-
Lee, F.S.1
Hagler, J.2
Chen, Z.J.3
Maniatis, T.4
-
14
-
-
0033563101
-
Signaling by proinflammatory cytokines. Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
-
Baud V, Liu ZG, Bennett B, Suzuki N, Xia Y, Karin M. Signaling by proinflammatory cytokines. Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev 1999: 13:1297-308.
-
(1999)
Genes Dev
, vol.13
, pp. 1297-1308
-
-
Baud, V.1
Liu, Z.G.2
Bennett, B.3
Suzuki, N.4
Xia, Y.5
Karin, M.6
-
15
-
-
0033605575
-
Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta
-
Zhao Q, Lee FS. Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta. J Biol Chem 1999: 274:8355-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 8355-8358
-
-
Zhao, Q.1
Lee, F.S.2
-
16
-
-
0034922161
-
The essential role of MEKK3 in TNF-induced NF-kappaB activation
-
Yang J, Lin Y, Guo Z, et al. The essential role of MEKK3 in TNF-induced NF-kappaB activation. Nat Immunol 2001: 2:620-4.
-
(2001)
Nat Immunol
, vol.2
, pp. 620-624
-
-
Yang, J.1
Lin, Y.2
Guo, Z.3
-
17
-
-
0031017618
-
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
-
Malinin NL, Boldin MP, Kovalenko AV, Wallach D. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature 1997: 385:540-4.
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
Wallach, D.4
-
18
-
-
17744371331
-
TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
-
Dumitru CD, Ceci JD, Tsatsanis C, et al. TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 2000: 103:1071-83.
-
(2000)
Cell
, vol.103
, pp. 1071-1083
-
-
Dumitru, C.D.1
Ceci, J.D.2
Tsatsanis, C.3
-
19
-
-
0029913457
-
Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase
-
Blank JL, Gerwins P, Elliott EM, Sather S, Johnson GL. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. J Biol Chem 1996: 271:5361-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 5361-5368
-
-
Blank, J.L.1
Gerwins, P.2
Elliott, E.M.3
Sather, S.4
Johnson, G.L.5
-
20
-
-
0035805552
-
MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression
-
Su B, Cheng J, Yang J, Guo Z. MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression. J Biol Chem 2001: 276:14784-90.
-
(2001)
J Biol Chem
, vol.276
, pp. 14784-14790
-
-
Su, B.1
Cheng, J.2
Yang, J.3
Guo, Z.4
-
21
-
-
0031036629
-
Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein kinase/ERK kinase kinase 3 (MEKK) derivative
-
Ellinger-Ziegelbauer H, Brown K, Kelly K, Siebenlist U. Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein kinase/ERK kinase kinase 3 (MEKK) derivative. J Biol Chem 1997: 272:2668-74.
-
(1997)
J Biol Chem
, vol.272
, pp. 2668-2674
-
-
Ellinger-Ziegelbauer, H.1
Brown, K.2
Kelly, K.3
Siebenlist, U.4
-
22
-
-
0030952084
-
Characterization of the mitogen-activated protein kinase kinase 4 (MKK4) /c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo
-
Deacon K, Blank JL. Characterization of the mitogen-activated protein kinase kinase 4 (MKK4) /c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo. J Biol Chem 1997: 272:14489-96.
-
(1997)
J Biol Chem
, vol.272
, pp. 14489-14496
-
-
Deacon, K.1
Blank, J.L.2
-
23
-
-
0033213597
-
Live cell fluorescence imaging of T cell MEKK2: Redistribution and activation in response to antigen stimulation of the T cell receptor
-
Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, Johnson GL, Monks CR. Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity 1999: 11:411-21.
-
(1999)
Immunity
, vol.11
, pp. 411-421
-
-
Schaefer, B.C.1
Ware, M.F.2
Marrack, P.3
Fanger, G.R.4
Kappler, J.W.5
Johnson, G.L.6
Monks, C.R.7
-
24
-
-
0034061264
-
Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation
-
Cheng J, Yang J, Xia Y, Karin M, Su B. Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol Cell Biol 2000: 20:2334-42.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2334-2342
-
-
Cheng, J.1
Yang, J.2
Xia, Y.3
Karin, M.4
Su, B.5
-
25
-
-
0034675925
-
MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells [In Process Citation]
-
Garrington TP, Ishizuka T, Papst PJ, et al.. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells [In Process Citation]. Embo J 2000: 19:5387-95.
-
(2000)
Embo J
, vol.19
, pp. 5387-5395
-
-
Garrington, T.P.1
Ishizuka, T.2
Papst, P.J.3
-
26
-
-
0346496017
-
Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
-
Huang Q, Yang J, Lin Y, Walker C, Cheng J, Liu ZG, Su B. Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3. Nat Immunol 2004: 5:98-103.
-
(2004)
Nat Immunol
, vol.5
, pp. 98-103
-
-
Huang, Q.1
Yang, J.2
Lin, Y.3
Walker, C.4
Cheng, J.5
Liu, Z.G.6
Su, B.7
-
27
-
-
0035875333
-
An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene
-
Myslinski E, Ame JC, Krol A, Carbon P. An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene. Nucl Acids Res 2001: 29:2502-9.
-
(2001)
Nucl Acids Res
, vol.29
, pp. 2502-2509
-
-
Myslinski, E.1
Ame, J.C.2
Krol, A.3
Carbon, P.4
-
28
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA 2003: 100:183-8.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.3
Baltimore, D.4
-
29
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, Naldini L, Trono D. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 1998: 72:9873-80.
-
(1998)
J Virol
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
Bukovsky, A.4
Quiroz, D.5
Naldini, L.6
Trono, D.7
-
30
-
-
0028705684
-
Generation of high-titer pseudotyped retroviral vectors with very broad host range
-
Yee JK, Friedmann T, Burns JC. Generation of high-titer pseudotyped retroviral vectors with very broad host range. Methods Cell Biol 1994: 43 Part A:99-112.
-
(1994)
Methods Cell Biol
, vol.43
, Issue.PART A
, pp. 99-112
-
-
Yee, J.K.1
Friedmann, T.2
Burns, J.C.3
-
31
-
-
0035836668
-
Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
-
Chayama K, Papst PJ, Garrington TP, et al.. Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells. Proc Natl Acad Sci USA 2001: 98:4599-604.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4599-4604
-
-
Chayama, K.1
Papst, P.J.2
Garrington, T.P.3
|