Ceftiofur impairs pro-inflammatory cytokine secretion through the inhibition of the activation of NF-κB and MAPK

Biochemical and Biophysical Research Communications

Volumn 372, Issue 1, 2008, Pages 73-77

  Ci, Xinxin ^a   Song, Yu ^a   Zeng, Fanqin ^a   Zhang, Xuemei ^a   Li, Hongyu ^a   Wang, Xinrui ^a   Cui, Junqing ^b   Deng, Xuming ^a  

^a JILIN UNIVERSITY   (China)

^b PFIZER INC   (United States)

Author keywords

Ceftiofur; Cytokines; LPS; MAPKs; NF B

Indexed keywords

CEFTIOFUR; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IMMUNOCYTOCHEMISTRY; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL NUCLEUS; CEPHALOSPORINS; CYTOKINES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 44649152241     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.170     Document Type: Article

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