The 3′ untranslated regions of influenza genomic sequences are 5′PPP-independent ligands for RIG-i

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Davis, William G ^a   Bowzard, J Bradford ^a   Sharma, Suresh D ^b   Wiens, Mayim E ^a   Ranjan, Priya ^a   Gangappa, Shivaprakash ^a   Stuchlik, Olga ^c   Pohl, Jan ^c   Donis, Ruben O ^a   Katz, Jacqueline M ^a   Cameron, Craig E ^b   Fujita, Takashi ^d   Sambhara, Suryaprakash ^a  

^a NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5' TRIPHOSPHATE; BETA INTERFERON; DOUBLE STRANDED RNA; LIGAND; PHOSPHATE; RETINOIC ACID INDUCIBLE PROTEIN I; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; 5'PPP RNA; 5'PPP-RNA; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; INS1 PROTEIN, INFLUENZA VIRUS; VIRUS PROTEIN; VIRUS RNA;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; GENE SEQUENCE; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; LIGAND BINDING; NONHUMAN; NS1 GENE; PROTEIN INDUCTION; RNA SEQUENCE; RNA STRUCTURE; VIRUS GENE; BINDING SITE; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CONFORMATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KINETICS; METABOLISM; PHYSIOLOGY; VIRUS GENOME;

ORTHOMYXOVIRIDAE;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; BINDING SITES; CELL LINE; DEAD-BOX RNA HELICASES; GENOME, VIRAL; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; INTERFERON-BETA; KINETICS; LIGANDS; NUCLEIC ACID CONFORMATION; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84863421511     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032661     Document Type: Article

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