Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Yu, Chung Ming ^a   Peng, Hung Pin ^a,b,e   Chen, Ing Chien ^a   Lee, Yu Ching ^a   Chen, Jun Bo ^a,c   Tsai, Keng Chang ^a   Chen, Ching Tai ^a,d,e   Chang, Jeng Yih ^a   Yang, Ei Wen ^a,e   Hsu, Po Chiang ^a   Jian, Jhih Wei ^a,b,e   Hsu, Hung Ju ^a,f   Chang, Hung Ju ^a,g,h   Hsu, Wen Lian ^e   Huang, Kai Fa ^h   Ma, Alex Che ^a   Yang, An Suei ^a  

^a GENOMICS RESEARCH CENTER   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^d NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^e INSTITUTE OF INFORMATION SCIENCE   (Taiwan)

^f NATIONAL DEFENSE UNIVERSITY   (Taiwan)

^g NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^h INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; VASCULOTROPIN ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; VASCULOTROPIN A;

ACCURACY; ANTIBODY COMBINING SITE; ANTIBODY STRUCTURE; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CRYSTAL STRUCTURE; EXPERIMENTAL DESIGN; HIGH THROUGHPUT SCREENING; INTERMETHOD COMPARISON; MACHINE LEARNING; MATHEMATICAL COMPUTING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PREDICTION; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PROTEIN STRUCTURE; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; THREE DIMENSIONAL IMAGING; ARTIFICIAL INTELLIGENCE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; IMMUNOLOGY; REPRODUCIBILITY; VALIDATION STUDY; X RAY CRYSTALLOGRAPHY;

ANIMALIA;

ANTIGEN-ANTIBODY REACTIONS; ARTIFICIAL INTELLIGENCE; BINDING SITES, ANTIBODY; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; REPRODUCIBILITY OF RESULTS; SINGLE-CHAIN ANTIBODIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84863338291     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033340     Document Type: Article

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