-
1
-
-
0025362523
-
In vivo tumor targeting of a recombinant single-chain antigen-binding protein
-
Colcher D, Bird R, Roselli M, Hardman KD, Johnson S, Pope S, Dodd SW, Pantoliano MW, Milenic DE and Schlom J: In vivo tumor targeting of a recombinant single-chain antigen-binding protein. J Natl Cancer Inst 1990;82:1191-1197.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1191-1197
-
-
Colcher, D.1
Bird, R.2
Roselli, M.3
Hardman, K.D.4
Johnson, S.5
Pope, S.6
Dodd, S.W.7
Pantoliano, M.W.8
Milenic, D.E.9
Schlom, J.10
-
2
-
-
0026327378
-
Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49
-
Milenic DE, Yokota T, Filpula DR, Finkelman MA, Dodd SW, Wood JF, Whitlow M, Snoy P, and Schlom J: Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res 1991;51:6363-6371.
-
(1991)
Cancer Res
, vol.51
, pp. 6363-6371
-
-
Milenic, D.E.1
Yokota, T.2
Filpula, D.R.3
Finkelman, M.A.4
Dodd, S.W.5
Wood, J.F.6
Whitlow, M.7
Snoy, P.8
Schlom, J.9
-
3
-
-
0027303686
-
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv
-
Adams GP, McCartney JE, Tai MS, Oppermann H, Huston JS, Stafford WF, 3rd, Bookman MA, Fand I, Houston LL, and Weiner LM: Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv. Cancer Res 1993;53:4026-4034.
-
(1993)
Cancer Res
, vol.53
, pp. 4026-4034
-
-
Adams, G.P.1
McCartney, J.E.2
Tai, M.S.3
Oppermann, H.4
Huston, J.S.5
Stafford 3rd, W.F.6
Bookman, M.A.7
Fand, I.8
Houston, L.L.9
Weiner, L.M.10
-
4
-
-
0029918942
-
Tumor localization of anti-CEA single-chain Fvs: Improved targeting by npn-covalent dimers
-
Wu AM, Chen W, Raubitschek A, Williams LE, Neumaier M, Fischer R, Hu SZ, Odom-Maryon T, Wong JY, and Shively JE: Tumor localization of anti-CEA single-chain Fvs: improved targeting by npn-covalent dimers. Immunotechnology 1996;2:21-36.
-
(1996)
Immunotechnology
, vol.2
, pp. 21-36
-
-
Wu, A.M.1
Chen, W.2
Raubitschek, A.3
Williams, L.E.4
Neumaier, M.5
Fischer, R.6
Hu, S.Z.7
Odom-Maryon, T.8
Wong, J.Y.9
Shively, J.E.10
-
5
-
-
0033046339
-
Binding characteristics and tumor targeting of a covalently linked divalent CC49 single-chain antibody
-
Beresford GW, Pavlinkova G, Booth BJ, Batra SK, and Colcher D: Binding characteristics and tumor targeting of a covalently linked divalent CC49 single-chain antibody. Int J Cancer 1999;81: 911-917.
-
(1999)
Int J Cancer
, vol.81
, pp. 911-917
-
-
Beresford, G.W.1
Pavlinkova, G.2
Booth, B.J.3
Batra, S.K.4
Colcher, D.5
-
6
-
-
0032870332
-
Pharmacokinetics and biodistribution of engineered single-chain antibody constructs of MAb CC49 in colon carcinoma xenografts
-
Pavlinkova G, Beresford GW, Booth BJ, Batra SK, and Colcher D: Pharmacokinetics and biodistribution of engineered single-chain antibody constructs of MAb CC49 in colon carcinoma xenografts. J Nucl Med 1999;40:1536-1546.
-
(1999)
J Nucl Med
, vol.40
, pp. 1536-1546
-
-
Pavlinkova, G.1
Beresford, G.W.2
Booth, B.J.3
Batra, S.K.4
Colcher, D.5
-
7
-
-
0014943238
-
Affinity and the immune response
-
Karush F: Affinity and the immune response. Ann NY Acad Sci 1970;169:56-64.
-
(1970)
Ann NY Acad Sci
, vol.169
, pp. 56-64
-
-
Karush, F.1
-
8
-
-
33644857036
-
Monospecific bivalent scFv-SH: Effects of linker length and location of an engineered cysteine on production, antigen binding activity and free SH accessibility
-
Albrecht H, Denardo GL, and Denardo SJ: Monospecific bivalent scFv-SH: effects of linker length and location of an engineered cysteine on production, antigen binding activity and free SH accessibility. J Immunol Methods 2006.
-
(2006)
J Immunol Methods
-
-
Albrecht, H.1
Denardo, G.L.2
Denardo, S.J.3
-
9
-
-
30344458506
-
A multivalent recombinant antibody fragment specific for carcinoembryonic antigen
-
Perez L, Ayala M, Pimentel G, Bell H, Canaan-Haden L, Bequet M, Gonzalez LJ, Miranda M, Ravelo R, Roque L, Acevedo B, Oliva JP, and Gavilondo JV: A multivalent recombinant antibody fragment specific for carcinoembryonic antigen. Biotechnol Appl Biochem 2006;43:39-48.
-
(2006)
Biotechnol Appl Biochem
, vol.43
, pp. 39-48
-
-
Perez, L.1
Ayala, M.2
Pimentel, G.3
Bell, H.4
Canaan-Haden, L.5
Bequet, M.6
Gonzalez, L.J.7
Miranda, M.8
Ravelo, R.9
Roque, L.10
Acevedo, B.11
Oliva, J.P.12
Gavilondo, J.V.13
-
10
-
-
0037436345
-
The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: Implications for diabody flexibility
-
Carmichael JA, Power BE, Garrett TP, Yazaki PJ, Shively JE, Raubischek AA, Wu AM, and Hudson PJ: The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility. J Mol Biol 2003;326:341-351.
-
(2003)
J Mol Biol
, vol.326
, pp. 341-351
-
-
Carmichael, J.A.1
Power, B.E.2
Garrett, T.P.3
Yazaki, P.J.4
Shively, J.E.5
Raubischek, A.A.6
Wu, A.M.7
Hudson, P.J.8
-
11
-
-
0028949091
-
Tetravalent miniantibodies with high avidity assembling in Escherichia coli
-
Pack P, Muller K, Zahn R, and Pluckthun A: Tetravalent miniantibodies with high avidity assembling in Escherichia coli. J Mol Biol 1995;246:28-34.
-
(1995)
J Mol Biol
, vol.246
, pp. 28-34
-
-
Pack, P.1
Muller, K.2
Zahn, R.3
Pluckthun, A.4
-
12
-
-
0034830739
-
Dimeric and trimeric antibodies: High avidity scFvs for cancer targeting
-
Kortt AA, Dolezal O, Power BE, and Hudson PJ: Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting. Biomol Eng 2001;18:95-108.
-
(2001)
Biomol Eng
, vol.18
, pp. 95-108
-
-
Kortt, A.A.1
Dolezal, O.2
Power, B.E.3
Hudson, P.J.4
-
13
-
-
0027197493
-
Diabodies: Small bivalent and bispecific antibody fragments
-
Holliger P, Prospero T, and Winter G: "Diabodies": Small bivalent and bispecific antibody fragments. Proc Natl Acad Sci USA 1993;90:6444-6448.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6444-6448
-
-
Holliger, P.1
Prospero, T.2
Winter, G.3
-
14
-
-
0030748513
-
Triabodies: Single chain Fv fragments without a linker form trivalent trimers
-
Iliades P, Kortt AA, and Hudson PJ: Triabodies: Single chain Fv fragments without a linker form trivalent trimers. FEBS Lett 1997;409:437-441.
-
(1997)
FEBS Lett
, vol.409
, pp. 437-441
-
-
Iliades, P.1
Kortt, A.A.2
Hudson, P.J.3
-
15
-
-
0029890636
-
Minibody: A novel engineered anticarcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts
-
Hu S, Shively L, Raubitschek A, Sherman M, Williams LE, Wong JY, Shively JE, and Wu AM: Minibody: A novel engineered anticarcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res 1996;56:3055-3061.
-
(1996)
Cancer Res
, vol.56
, pp. 3055-3061
-
-
Hu, S.1
Shively, L.2
Raubitschek, A.3
Sherman, M.4
Williams, L.E.5
Wong, J.Y.6
Shively, J.E.7
Wu, A.M.8
-
16
-
-
0032403273
-
Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis
-
Reiter Y and Pastan I: Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis. Trends Biotechnol 1998;16:513-520.
-
(1998)
Trends Biotechnol
, vol.16
, pp. 513-520
-
-
Reiter, Y.1
Pastan, I.2
-
17
-
-
33751017388
-
Optimizing the generation of recombinant single-chain antibodies against placental alkaline phosphatase
-
Sheikholvaezin A, Sandstrom P, Eriksson D, Norgren N, Riklund K, and Stigbrand T: Optimizing the generation of recombinant single-chain antibodies against placental alkaline phosphatase. Hybridoma 2006;25:181-192.
-
(2006)
Hybridoma
, vol.25
, pp. 181-192
-
-
Sheikholvaezin, A.1
Sandstrom, P.2
Eriksson, D.3
Norgren, N.4
Riklund, K.5
Stigbrand, T.6
-
18
-
-
0020508096
-
Antigenic determinants of human placental and testicular placental-like alkaline phosphatases as mapped by monoclonal antibodies
-
Millan JL and Stigbrand T: Antigenic determinants of human placental and testicular placental-like alkaline phosphatases as mapped by monoclonal antibodies. Eur J Biochem 1983;136:1-7.
-
(1983)
Eur J Biochem
, vol.136
, pp. 1-7
-
-
Millan, J.L.1
Stigbrand, T.2
-
19
-
-
0031740502
-
Differences in sequence and affinity between three monoclonal anti-idiotypic antibodies against one anti-placental alkaline phosphatase idiotypic antibody
-
Sandstrom PJA, Ullen A, Behravan G, and Stigbrand T: Differences in sequence and affinity between three monoclonal anti-idiotypic antibodies against one anti-placental alkaline phosphatase idiotypic antibody. Tumor Targeting 1998;3:80-86.
-
(1998)
Tumor Targeting
, vol.3
, pp. 80-86
-
-
Sandstrom, P.J.A.1
Ullen, A.2
Behravan, G.3
Stigbrand, T.4
-
20
-
-
0003046374
-
Producing antibodies in Escherichia coli: From PCR to fermentation
-
McCafferty J, Hoogenboom HR, and Chiswell DJ Eds, IRL Press, Oxford
-
Pluckthun A KA, Krebber C, Horn U, Knupfer U, Wenderoth R, Nieba L, Proba K, and Riesenberg D: Producing antibodies in Escherichia coli: From PCR to fermentation. In: Antibody Engineering. McCafferty J, Hoogenboom HR, and Chiswell DJ (Eds.). IRL Press, Oxford, 1996, pp. 203-252.
-
(1996)
Antibody Engineering
, pp. 203-252
-
-
Pluckthun, A.K.1
Krebber, C.2
Horn, U.3
Knupfer, U.4
Wenderoth, R.5
Nieba, L.6
Proba, K.7
Riesenberg, D.8
-
21
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
22
-
-
0029849896
-
Single-chain Fv radioimmunotargeting
-
Huston JS, George AJ, Adams GP, Stafford WF, Jamar F, Tai MS, McCartney JE, Oppermann H, Heelan BT, Peters AM, Houston LL, Bookman MA, Wolf EJ, and Weiner LM: Single-chain Fv radioimmunotargeting. Q J Nucl Med 1996;40:320-333.
-
(1996)
Q J Nucl Med
, vol.40
, pp. 320-333
-
-
Huston, J.S.1
George, A.J.2
Adams, G.P.3
Stafford, W.F.4
Jamar, F.5
Tai, M.S.6
McCartney, J.E.7
Oppermann, H.8
Heelan, B.T.9
Peters, A.M.10
Houston, L.L.11
Bookman, M.A.12
Wolf, E.J.13
Weiner, L.M.14
-
24
-
-
0028140247
-
Construction, expression, and activity of a bivalent bispecific single-chain antibody
-
Mallender WD and Voss EW, Jr.: Construction, expression, and activity of a bivalent bispecific single-chain antibody. J Biol Chem 1994;269:199-206.
-
(1994)
J Biol Chem
, vol.269
, pp. 199-206
-
-
Mallender, W.D.1
Voss Jr., E.W.2
-
25
-
-
0025978976
-
Man-made antibodies
-
Winter G and Milstein C: Man-made antibodies. Nature 1991;349: 293-299.
-
(1991)
Nature
, vol.349
, pp. 293-299
-
-
Winter, G.1
Milstein, C.2
-
26
-
-
0021832361
-
Hybrid antibodies can target sites for attack by T cells
-
Staerz UD, Kanagawa O, and Bevan MJ: Hybrid antibodies can target sites for attack by T cells. Nature 1985;314:628-631.
-
(1985)
Nature
, vol.314
, pp. 628-631
-
-
Staerz, U.D.1
Kanagawa, O.2
Bevan, M.J.3
-
27
-
-
0023126589
-
The use of hybrid hybridomas to target human cytotoxic T lymphocytes
-
Lanzavecchia A and Scheidegger D: The use of hybrid hybridomas to target human cytotoxic T lymphocytes. Eur J Immunol 1987;17:105-111.
-
(1987)
Eur J Immunol
, vol.17
, pp. 105-111
-
-
Lanzavecchia, A.1
Scheidegger, D.2
-
28
-
-
0030738617
-
New protein engineering approaches to multivalent and bispecific antibody fragments
-
Pluckthun A and Pack P: New protein engineering approaches to multivalent and bispecific antibody fragments. Immunotechnology 1997;3:83-105.
-
(1997)
Immunotechnology
, vol.3
, pp. 83-105
-
-
Pluckthun, A.1
Pack, P.2
-
29
-
-
0026772358
-
Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate
-
Cumber AJ, Ward ES, Winter G, Parnell GD, and Wawrzynczak EJ: Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate. J Immunol 1992;149:120-126.
-
(1992)
J Immunol
, vol.149
, pp. 120-126
-
-
Cumber, A.J.1
Ward, E.S.2
Winter, G.3
Parnell, G.D.4
Wawrzynczak, E.J.5
-
30
-
-
0028302596
-
Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli
-
Gruber M, Schodin BA, Wilson ER, and Kranz DM: Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli. J Immunol 1994;152:5368-5374.
-
(1994)
J Immunol
, vol.152
, pp. 5368-5374
-
-
Gruber, M.1
Schodin, B.A.2
Wilson, E.R.3
Kranz, D.M.4
-
31
-
-
0028236196
-
Single-chain mono- and bispecific antibody derivatives with novel biological properties and antitumour activity from a COS cell transient expression system
-
Hayden MS, Linsley PS, Gayle MA, Bajorath J, Brady WA, Norris NA, Fell HP, Ledbetter JA, and Gilliland LK: Single-chain mono- and bispecific antibody derivatives with novel biological properties and antitumour activity from a COS cell transient expression system. Ther Immunol 1994;1:3-15.
-
(1994)
Ther Immunol
, vol.1
, pp. 3-15
-
-
Hayden, M.S.1
Linsley, P.S.2
Gayle, M.A.3
Bajorath, J.4
Brady, W.A.5
Norris, N.A.6
Fell, H.P.7
Ledbetter, J.A.8
Gilliland, L.K.9
-
32
-
-
0029614330
-
Production and characterization of bispecific single-chain antibody fragments
-
De Jonge J, Brissinck J, Heirman C, Demanet C, Leo O, Moser M, and Thielemans K: Production and characterization of bispecific single-chain antibody fragments. Mol Immunol 1995;32:1405-1412.
-
(1995)
Mol Immunol
, vol.32
, pp. 1405-1412
-
-
De Jonge, J.1
Brissinck, J.2
Heirman, C.3
Demanet, C.4
Leo, O.5
Moser, M.6
Thielemans, K.7
-
33
-
-
0029932582
-
Specific killing of lymphoma cells by cytotoxic T-cells mediated by a bispecific diabody
-
Holliger P, Brissinck J, Williams RL, Thielemans K, and Winter G: Specific killing of lymphoma cells by cytotoxic T-cells mediated by a bispecific diabody. Protein Eng 1996;9:299-305.
-
(1996)
Protein Eng
, vol.9
, pp. 299-305
-
-
Holliger, P.1
Brissinck, J.2
Williams, R.L.3
Thielemans, K.4
Winter, G.5
-
34
-
-
0029851132
-
Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent antitumour Fab′ fragments
-
Casey JL, King DJ, Chaplin LC, Haines AM, Pedley RB, Mountain A, Yarranton GT, and Begent RH: Preparation, characterisation and tumour targeting of cross-linked divalent and trivalent antitumour Fab′ fragments. Br J Cancer 1996;74:1397-1405.
-
(1996)
Br J Cancer
, vol.74
, pp. 1397-1405
-
-
Casey, J.L.1
King, D.J.2
Chaplin, L.C.3
Haines, A.M.4
Pedley, R.B.5
Mountain, A.6
Yarranton, G.T.7
Begent, R.H.8
-
35
-
-
0022378268
-
Radiolabeled monoclonal anti-tumor antibodies in diagnosis and therapy
-
Larson SM: Radiolabeled monoclonal anti-tumor antibodies in diagnosis and therapy. J Nucl Med 1985;26:538-545.
-
(1985)
J Nucl Med
, vol.26
, pp. 538-545
-
-
Larson, S.M.1
|