A "solvated rotamer" approach to modeling water-mediated hydrogen bonds at protein-protein interfaces

Proteins: Structure, Function and Genetics

Volumn 58, Issue 4, 2005, Pages 893-904

  Jiang, Lin ^a   Kuhlman, Brian ^b   Kortemme, Tanja ^c   Baker, David ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Free energy function; Hydration; Protein design; Protein protein interactions; Solvent modeling; Water mediated hydrogen bonds

Indexed keywords

HYDROGEN; MONOMER; NUCLEIC ACID; PROTEIN; ROTAMER; SOLVENT; UNCLASSIFIED DRUG; WATER;

ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; CALCULATION; CRYSTAL STRUCTURE; ENERGY TRANSFER; HYDROGEN BOND; MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; SOLVATION; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; AMINO ACID SEQUENCE; AMINO ACIDS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DATABASES, PROTEIN; ELECTROSTATICS; HYDROGEN BONDING; MODELS, MOLECULAR; NITROGEN; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION MAPPING; PROTEINS; PROTEOMICS; SOLVENTS; TEMPERATURE; THERMODYNAMICS; WATER;

EID: 13944256616     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20347     Document Type: Article

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