Aglycosylated antibodies and antibody fragments produced in a scalable in vitro transcription-translation system

mAbs

Volumn 4, Issue 2, 2012, Pages 217-225

  Yin, Gang ^a   Garces, Eudean D ^a   Yang, Junhao ^a   Zhang, Juan ^a   Tran, Cuong ^a   Steiner, Alexander R ^a   Roos, Christine ^a   Bajad, Sunil ^a   Hudak, Susan ^a   Penta, Kalyani ^a   Zawada, James ^a   Pollitt, Sonia ^a   Murray, Christopher J ^a  

^a Sutro Biopharma Inc   (United States)

Author keywords

Aglycosylated antibodies; Cell free protein synthesis; Fab antibody; HER2; Trastuzumab

Indexed keywords

DNA; IMMUNOGLOBULIN G; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 23; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TRASTUZUMAB; IL13RA1 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA TEMPLATE; ESCHERICHIA COLI; GLYCOSYLATION; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN SYNTHESIS; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL FREE SYSTEM; CHEMISTRY; GENETIC TRANSCRIPTION; GENETICS; HUMAN; IMMUNOLOGY;

CELL-FREE SYSTEM; GLYCOSYLATION; HUMANS; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; INTERLEUKIN-23; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; SINGLE-CHAIN ANTIBODIES; TRANSCRIPTION, GENETIC;

EID: 84863249248     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.4.2.19202     Document Type: Article

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