Inhibition of the NFAT pathway alleviates amyloid beta neurotoxicity in a mouse model of Alzheimer's disease

Journal of Neuroscience

Volumn 32, Issue 9, 2012, Pages 3176-3192

  Hudry, Eloise ^a   Wu, Hai Yan ^a   Arbel Ornath, Michal ^a   Hashimoto, Tadafumi ^a   Matsouaka, Roland ^b   Fan, Zhanyun ^a   Spires Jones, Tara L ^a   Betensky, Rebecca A ^b   Bacskai, Brian J ^a   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CALCINEURIN; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR; PEPTIDE; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; VIVIT PEPTIDE;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; EMBRYO; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOLOGY; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; DENDRITES; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; MICE; MICE, TRANSGENIC; NEURAL INHIBITION; NFATC TRANSCRIPTION FACTORS; OLIGOPEPTIDES; SIGNAL TRANSDUCTION;

EID: 84863238028     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6439-11.2012     Document Type: Article

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