-
1
-
-
0036512435
-
Multiple myeloma: Evolving genetic events and host interactions
-
Kuehl WM, Bergsagel PL. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer. 2002;2(3):175-187. (Pubitemid 37328787)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.3
, pp. 175-187
-
-
Kuehl, W.M.1
Bergsagel, P.L.2
-
2
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 2000;102(5): 553-563.
-
(2000)
Cell
, vol.102
, Issue.5
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
3
-
-
77952583868
-
Preventing AID, a physiological mutator, from deleterious activation: Regulation of the genomic instability that is associated with antibody diversity
-
Nagaoka H, Tran TH, Kobayashi M, Aida M, Honjo T. Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity. Int Immunol. 2010;22(4):227-235.
-
(2010)
Int Immunol
, vol.22
, Issue.4
, pp. 227-235
-
-
Nagaoka, H.1
Tran, T.H.2
Kobayashi, M.3
Aida, M.4
Honjo, T.5
-
4
-
-
39149099085
-
Two levels of protection for the B cell genome during somatic hypermutation
-
DOI 10.1038/nature06547, PII NATURE06547
-
Liu M, Duke JL, Richter DJ, et al. Two levels of protection for the B cell genome during somatic hypermutation. Nature. 2008;451(7180):841-845. (Pubitemid 351253166)
-
(2008)
Nature
, vol.451
, Issue.7180
, pp. 841-845
-
-
Liu, M.1
Duke, J.L.2
Richter, D.J.3
Vinuesa, C.G.4
Goodnow, C.C.5
Kleinstein, S.H.6
Schatz, D.G.7
-
5
-
-
4644257592
-
AID is required for c-myc/IgH chromosome translocations in vivo
-
DOI 10.1016/j.cell.2004.08.006, PII S0092867404007524
-
Ramiro AR, Jankovic M, Eisenreich T, et al. AID is required for c-myc/IgH chromosome translocations in vivo. Cell. 2004;118(4):431-438. (Pubitemid 39485663)
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 431-438
-
-
Ramiro, A.R.1
Jankovic, M.2
Eisenreich, T.3
Difilippantonio, S.4
Chen-Kiang, S.5
Muramatsu, M.6
Honjo, T.7
Nussenzweig, A.8
Nussenzweig, M.C.9
-
6
-
-
8644241815
-
Expression of the AID protein in normal and neoplastic B cells
-
DOI 10.1182/blood-2004-04-1558
-
Pasqualucci L, Guglielmino R, Houldsworth J, et al. Expression of the AID protein in normal and neoplastic B cells. Blood. 2004;104(10):3318-3325. (Pubitemid 39507152)
-
(2004)
Blood
, vol.104
, Issue.10
, pp. 3318-3325
-
-
Pasqualucci, L.1
Guglielmino, R.2
Houldsworth, J.3
Mohr, J.4
Aoufouchi, S.5
Polakiewicz, R.6
Chaganti, R.S.K.7
Dalla-Favera, R.8
-
7
-
-
36749011232
-
The malignant clone and the bonemarrow environment
-
Podar K, Richardson PG, Hideshima T, Chauhan D, Anderson KC. The malignant clone and the bonemarrow environment. Best Pract Res Clin Haematol. 2007;20:597-612.
-
(2007)
Best Pract Res Clin Haematol
, vol.20
, pp. 597-612
-
-
Podar, K.1
Richardson, P.G.2
Hideshima, T.3
Chauhan, D.4
Anderson, K.C.5
-
8
-
-
34249671217
-
CD28-mediated regulation of multiple myeloma cell proliferation and survival
-
DOI 10.1182/blood-2006-03-012542
-
Bahlis NJ, King AM, Kolonias D, et al. CD28-mediated regulation of multiple myeloma cell proliferation and survival. Blood. 2007;109(11):5002-5010. (Pubitemid 46827800)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 5002-5010
-
-
Bahlis, N.J.1
King, A.M.2
Kolonias, D.3
Carlson, L.M.4
Hong, Y.L.5
Hussein, M.A.6
Terebelo, H.R.7
Byrne Jr., G.E.8
Levine, B.L.9
Boise, L.H.10
Lee, K.P.11
-
9
-
-
0030709310
-
Localization of Kaposi's sarcoma-associated herpesvirus in bone marrow biopsy samples from patients with multiple myeloma
-
Said JW, Rettig MR, Heppner K, et al. Localization of Kaposi's sarcoma-associated herpesvirus in bone marrow biopsy samples from patients with multiple myeloma. Blood. 1997;90(11):4278-4282. (Pubitemid 27508433)
-
(1997)
Blood
, vol.90
, Issue.11
, pp. 4278-4282
-
-
Said, J.W.1
Rettig, M.R.2
Heppner, K.3
Vescio, R.A.4
Schiller, G.5
Ma, H.J.6
Belson, D.7
Savage, A.8
Shintaku, I.P.9
Koeffier, H.P.10
Asou, H.11
Pinkus, G.12
Pinkus, J.13
Schrage, M.14
Green, E.15
Berenson, J.R.16
-
10
-
-
70349577375
-
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: A therapeutic target
-
Chauhan D, Singh AV, Brahmandam M, et al. Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. Cancer Cell. 2009;16(4):309-323.
-
(2009)
Cancer Cell
, vol.16
, Issue.4
, pp. 309-323
-
-
Chauhan, D.1
Singh, A.V.2
Brahmandam, M.3
-
11
-
-
33746912289
-
Enhancement of clonogenicity of human multiple myeloma by dendritic cells
-
DOI 10.1084/jem.20052136
-
Kukreja A, Hutchinson A, Dhodapkar K, et al. Enhancement of clonogenicity of human multiple myeloma by dendritic cells. J Exp Med. 2006; 203(8):1859-1865. (Pubitemid 44188460)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.8
, pp. 1859-1865
-
-
Kukreja, A.1
Hutchinson, A.2
Dhodapkar, K.3
Mazumder, A.4
Vesole, D.5
Angitapalli, R.6
Jagannath, S.7
Dhodapkar, M.V.8
-
12
-
-
53449089919
-
Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma
-
Dhodapkar KM, Barbuto S, Matthews P, et al. Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma. Blood. 2008;112(7):2878-2885.
-
(2008)
Blood
, vol.112
, Issue.7
, pp. 2878-2885
-
-
Dhodapkar, K.M.1
Barbuto, S.2
Matthews, P.3
-
13
-
-
33750614944
-
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after DC injection of cytokine matured DCs in myeloma patients
-
Banerjee D, Dhodapkar MV, Matayeva E, Steinman RM, Dhodapkar K. Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after DC injection of cytokine matured DCs in myeloma patients. Blood. 2006;108(8):2655-2661.
-
(2006)
Blood
, vol.108
, Issue.8
, pp. 2655-2661
-
-
Banerjee, D.1
Dhodapkar, M.V.2
Matayeva, E.3
Steinman, R.M.4
Dhodapkar, K.5
-
14
-
-
79551635705
-
Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions
-
Dickhout JG, Lhotak S, Hilditch BA, et al. Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions. FASEB J. 2011;25:576-589.
-
(2011)
FASEB J
, vol.25
, pp. 576-589
-
-
Dickhout, J.G.1
Lhotak, S.2
Hilditch, B.A.3
-
15
-
-
78149475282
-
A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells
-
Lee H, Trott JS, Haque S, McCormick S, Chiorazzi N, Mongini PK. A cyclooxygenase-2/prostaglandin E2 pathway augments activation-induced cytosine deaminase expression within replicating human B cells. J Immunol. 2010; 185(9):5300-5314.
-
(2010)
J Immunol
, vol.185
, Issue.9
, pp. 5300-5314
-
-
Lee, H.1
Trott, J.S.2
Haque, S.3
McCormick, S.4
Chiorazzi, N.5
Mongini, P.K.6
-
16
-
-
58149470357
-
Impaired NHEJ function in multiple myeloma
-
Yang C, Betti C, Singh S, Toor A, Vaughan A. Impaired NHEJ function in multiple myeloma. Mutat Res. 2009;660(1-2):66-73.
-
(2009)
Mutat Res
, vol.660
, Issue.1-2
, pp. 66-73
-
-
Yang, C.1
Betti, C.2
Singh, S.3
Toor, A.4
Vaughan, A.5
-
17
-
-
77958500026
-
Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas
-
Cheong C, Matos I, Choi JH, et al. Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell. 2010;143(3):416-429.
-
(2010)
Cell
, vol.143
, Issue.3
, pp. 416-429
-
-
Cheong, C.1
Matos, I.2
Choi, J.H.3
-
18
-
-
0033104851
-
Detection of Kaposi's sarcoma herpesvirus DNA sequences in multiple myeloma bone marrow stromal cells
-
Chauhan D, Bharti A, Raje N, et al. Detection of Kaposi's sarcoma herpesvirus DNA sequences in multiple myeloma bone marrow stromal cells. Blood. 1999;93(5):1482-1486. (Pubitemid 29102473)
-
(1999)
Blood
, vol.93
, Issue.5
, pp. 1482-1486
-
-
Chauhan, D.1
Bharti, A.2
Raje, N.3
Gustafson, E.4
Pinkus, G.S.5
Pinkus, J.L.6
Teoh, G.7
Hideshima, T.8
Treon, S.P.9
Fingeroth, J.D.10
Anderson, K.C.11
-
19
-
-
34047118525
-
Osteoprotegerin expression in dendritic cells increases with maturation and is NF-kappaB-dependent
-
DOI 10.1002/jcb.21129
-
Schoppet M, Henser S, Ruppert V, et al. Osteoprotegerin expression in dendritic cells increases with maturation and is NF-kappaB-dependent. J Cell Biochem. 2007;100(6):1430-1439. (Pubitemid 46515577)
-
(2007)
Journal of Cellular Biochemistry
, vol.100
, Issue.6
, pp. 1430-1439
-
-
Schoppet, M.1
Hehser, S.2
Ruppert, V.3
Stubig, T.4
Al-Fakhri, N.5
Maisch, B.6
Hofbauer, L.C.7
-
20
-
-
56549098575
-
RANK/RANKL: Regulators of immune responses and bone physiology
-
Leibbrandt A, Penninger JM. RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci. 2008;1143(11):123-150.
-
(2008)
Ann N Y Acad Sci
, vol.1143
, Issue.11
, pp. 123-150
-
-
Leibbrandt, A.1
Penninger, J.M.2
-
21
-
-
70350464349
-
A coming-of-age story: Activation-induced cytidine deaminase turns 10
-
Delker RK, Fugmann SD, Papavasiliou FN. A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat Immunol. 2009;10(11): 1147-1153.
-
(2009)
Nat Immunol
, vol.10
, Issue.11
, pp. 1147-1153
-
-
Delker, R.K.1
Fugmann, S.D.2
Papavasiliou, F.N.3
-
22
-
-
77955921194
-
Widespread genomic breaks generated by activationinduced cytidine deaminase are prevented by homologous recombination
-
Hasham MG, Donghia NM, Coffey E, et al. Widespread genomic breaks generated by activationinduced cytidine deaminase are prevented by homologous recombination. Nat Immunol. 2010; 11(9):820-826.
-
(2010)
Nat Immunol
, vol.11
, Issue.9
, pp. 820-826
-
-
Hasham, M.G.1
Donghia, N.M.2
Coffey, E.3
-
23
-
-
77950961695
-
GammaH2AX: A sensitive molecular marker of DNA damage and repair
-
Mah LJ, El-Osta A, Karagiannis TC. gammaH2AX: a sensitive molecular marker of DNA damage and repair. Leukemia. 2010;24(4):679-686.
-
(2010)
Leukemia
, vol.24
, Issue.4
, pp. 679-686
-
-
Mah, L.J.1
El-Osta, A.2
Karagiannis, T.C.3
-
24
-
-
79960598123
-
Immature dendritic cells from patients with multiple myeloma are prone to osteoclast differentiation in vitro
-
Tucci M, Ciavarella S, Strippoli S, Brunetti O, Dammacco F, Silvestris F. Immature dendritic cells from patients with multiple myeloma are prone to osteoclast differentiation in vitro. Exp Hematol. 2011;39(7):773-783.e1.
-
(2011)
Exp Hematol
, vol.39
, Issue.7
-
-
Tucci, M.1
Ciavarella, S.2
Strippoli, S.3
Brunetti, O.4
Dammacco, F.5
Silvestris, F.6
-
25
-
-
79960880111
-
Dendritic cells and malignant plasma cells: An alliance in multiple myeloma tumor progression?
-
Tucci M, Stucci S, Strippoli S, Dammacco F, Silvestris F. Dendritic cells and malignant plasma cells: an alliance in multiple myeloma tumor progression? Oncologist. 2011;16(7):1040-1048.
-
(2011)
Oncologist
, vol.16
, Issue.7
, pp. 1040-1048
-
-
Tucci, M.1
Stucci, S.2
Strippoli, S.3
Dammacco, F.4
Silvestris, F.5
-
26
-
-
33845496508
-
Bortezomib disrupts tumour-dendritic cell interactions in myeloma and lymphoma: Therapeutic implications
-
DOI 10.1111/j.1365-2141.2006.06369.x
-
Kukreja A, Hutchinson A, Mazumder A, et al. Bortezomib disrupts tumor-dendritic cell interactions in myeloma and lymphoma: therapeutic implications. Br J Haematol. 2006;136(1):106-110. (Pubitemid 44912594)
-
(2007)
British Journal of Haematology
, vol.136
, Issue.1
, pp. 106-110
-
-
Kukreja, A.1
Hutchinson, A.2
Mazumder, A.3
Vesole, D.4
Angitapalli, R.5
Jagannath, S.6
O'Connor, O.A.7
Dhodapkar, M.V.8
-
27
-
-
70350710809
-
Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: Implications for bone disease
-
Kukreja A, Radfar S, Sun BH, Insogna K, Dhodapkar MV. Dominant role of CD47-thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease. Blood. 2009;114(16):3413-3421.
-
(2009)
Blood
, vol.114
, Issue.16
, pp. 3413-3421
-
-
Kukreja, A.1
Radfar, S.2
Sun, B.H.3
Insogna, K.4
Dhodapkar, M.V.5
-
28
-
-
77950955761
-
Origin of chromosomal translocations in lymphoid cancer
-
Nussenzweig A, Nussenzweig MC. Origin of chromosomal translocations in lymphoid cancer. Cell. 2010;141(1):27-38.
-
(2010)
Cell
, vol.141
, Issue.1
, pp. 27-38
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
29
-
-
38549131395
-
AID-Dependent Activation of a MYC Transgene Induces Multiple Myeloma in a Conditional Mouse Model of Post-Germinal Center Malignancies
-
DOI 10.1016/j.ccr.2008.01.007, PII S153561080800007X
-
Chesi M, Robbiani DF, Sebag M, et al. AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies. Cancer Cell. 2008;13(2):167-180. (Pubitemid 351163163)
-
(2008)
Cancer Cell
, vol.13
, Issue.2
, pp. 167-180
-
-
Chesi, M.1
Robbiani, D.F.2
Sebag, M.3
Chng, W.J.4
Affer, M.5
Tiedemann, R.6
Valdez, R.7
Palmer, S.E.8
Haas, S.S.9
Stewart, A.K.10
Fonseca, R.11
Kremer, R.12
Cattoretti, G.13
Bergsagel, P.L.14
-
30
-
-
59449102152
-
Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes
-
Casellas R, Yamane A, Kovalchuk AL, Potter M. Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes. Immunology. 2009;126(3):316-328.
-
(2009)
Immunology
, vol.126
, Issue.3
, pp. 316-328
-
-
Casellas, R.1
Yamane, A.2
Kovalchuk, A.L.3
Potter, M.4
-
31
-
-
51049110262
-
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development
-
Takizawa M, Tolarova H, Li Z, et al. AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development. J Exp Med. 2008;205(9): 1949-1957.
-
(2008)
J Exp Med
, vol.205
, Issue.9
, pp. 1949-1957
-
-
Takizawa, M.1
Tolarova, H.2
Li, Z.3
-
32
-
-
77953955599
-
High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: Link with an activated microenvironment in CLL disease
-
Palacios F, Moreno P, Morande P, et al. High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease. Blood. 2010;115(22):4488-4496.
-
(2010)
Blood
, vol.115
, Issue.22
, pp. 4488-4496
-
-
Palacios, F.1
Moreno, P.2
Morande, P.3
-
33
-
-
60549115641
-
Estrogen directly activates AID transcription and function
-
Pauklin S, Sernandez IV, Bachmann G, Ramiro AR, Petersen-Mahrt SK. Estrogen directly activates AID transcription and function. J Exp Med. 2009;206(1): 99-111.
-
(2009)
J Exp Med
, vol.206
, Issue.1
, pp. 99-111
-
-
Pauklin, S.1
Sernandez, I.V.2
Bachmann, G.3
Ramiro, A.R.4
Petersen-Mahrt, S.K.5
-
34
-
-
0033571785
-
In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
-
Bell D, Chomarat P, Broyles D, et al. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med. 1999;190(10):1417-1426.
-
(1999)
J Exp Med
, vol.190
, Issue.10
, pp. 1417-1426
-
-
Bell, D.1
Chomarat, P.2
Broyles, D.3
-
35
-
-
33744967284
-
A Role for Activation-Induced Cytidine Deaminase in the Host Response against a Transforming Retrovirus
-
DOI 10.1016/j.immuni.2006.03.021, PII S1074761306002329
-
Gourzi P, Leonova T, Papavasiliou FN. A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus. Immunity. 2006;24(6):779-786. (Pubitemid 43867362)
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 779-786
-
-
Gourzi, P.1
Leonova, T.2
Papavasiliou, F.N.3
-
36
-
-
33644643189
-
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations
-
DOI 10.1038/nature04495, PII N04495
-
Ramiro AR, Jankovic M, Callen E, et al. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature. 2006; 440(7080):105-109. (Pubitemid 43336276)
-
(2006)
Nature
, vol.440
, Issue.7080
, pp. 105-109
-
-
Ramiro, A.R.1
Jankovic, M.2
Callen, E.3
Difilippantonio, S.4
Chen, H.-T.5
McBride, K.M.6
Eisenreich, T.R.7
Chen, J.8
Dickins, R.A.9
Lowe, S.W.10
Nussenzweig, A.11
Nussenzweig, M.C.12
-
37
-
-
79961087495
-
Controversies in clinical cancer dormancy
-
Uhr JW, Pantel K. Controversies in clinical cancer dormancy. Proc Natl Acad Sci U S A. 2011; 108(30):12396-12400.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.30
, pp. 12396-12400
-
-
Uhr, J.W.1
Pantel, K.2
-
38
-
-
0022374035
-
The relative spatial distribution of CFU-S in the mouse spleen
-
Ploemacher RE, Brons NH. The relative spatial distribution of CFU-S in the mouse spleen. Exp Hematol. 1985;13(10):1068-1072. (Pubitemid 16172302)
-
(1985)
Experimental Hematology
, vol.13
, Issue.10
, pp. 1068-1072
-
-
Ploemacher, R.E.1
Brons, N.H.C.2
-
39
-
-
0345599884
-
Vigorous Premalignancy-specific Effector T Cell Response in the Bone Marrow of Patients with Monoclonal Gammopathy
-
DOI 10.1084/jem.20031030
-
Dhodapkar MV, Krasovsky J, Osman K, Geller MD. Vigorous premalignancy-specific effector T cell response in the bone marrow of patients with monoclonal gammopathy. J Exp Med. 2003;198(11):1753-1757. (Pubitemid 37494167)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.11
, pp. 1753-1757
-
-
Dhodapkar, M.V.1
Krasovsky, J.2
Osman, K.3
Geller, M.D.4
-
40
-
-
39549084084
-
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma
-
DOI 10.1073/pnas.0711293105
-
Jinushi M, Vanneman M, Munshi NC, et al. MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc Natl Acad Sci U S A. 2008;105(4):1285-1290. (Pubitemid 351397045)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.4
, pp. 1285-1290
-
-
Jinushi, M.1
Vanneman, M.2
Munshi, N.C.3
Tai, Y.-T.4
Prabhala, R.H.5
Ritz, J.6
Neuberg, D.7
Anderson, K.C.8
Carrasco, D.R.9
Dranoff, G.10
-
41
-
-
79960372865
-
Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells
-
Rozanski CH, Arens R, Carlson LM, et al. Sustained antibody responses depend on CD28 function in bone marrow-resident plasma cells. J Exp Med. 2011;208(7):1435-1446.
-
(2011)
J Exp Med
, vol.208
, Issue.7
, pp. 1435-1446
-
-
Rozanski, C.H.1
Arens, R.2
Carlson, L.M.3
|