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Volumn 25, Issue 2, 2011, Pages 576-589

Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions

Author keywords

Apoptosis; Atherosclerosis; Cellular transformation; ER stress; GRP78

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA; SCAVENGER RECEPTOR; X BOX BINDING PROTEIN 1;

EID: 79551635705     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-159319     Document Type: Article
Times cited : (43)

References (68)
  • 1
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis. The road ahead
    • Glass, C. K., and Witztum, J. L. (2001) Atherosclerosis. The road ahead. Cell 104, 503-516
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 2
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A. J. (2000) Atherosclerosis. Nature 407, 233-241
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 4
    • 0036995812 scopus 로고    scopus 로고
    • Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals
    • Takahashi, K., Takeya, M., and Sakashita, N. (2002) Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals. Med. Electron Microsc. 35, 179-203
    • (2002) Med. Electron Microsc. , vol.35 , pp. 179-203
    • Takahashi, K.1    Takeya, M.2    Sakashita, N.3
  • 5
    • 38849162120 scopus 로고    scopus 로고
    • Macrophage differentiation and function in health and disease
    • Naito, M. (2008) Macrophage differentiation and function in health and disease. Pathol. Int. 58, 143-155
    • (2008) Pathol. Int. , vol.58 , pp. 143-155
    • Naito, M.1
  • 6
    • 0030474490 scopus 로고    scopus 로고
    • Foam cell apoptosis and the development of the lipid core of human atherosclerosis
    • Hegyi, L., Skepper, J. N., Cary, N. R., and Mitchinson, M. J. (1996) Foam cell apoptosis and the development of the lipid core of human atherosclerosis. J. Pathol. 180, 423-429
    • (1996) J. Pathol. , vol.180 , pp. 423-429
    • Hegyi, L.1    Skepper, J.N.2    Cary, N.R.3    Mitchinson, M.J.4
  • 8
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby, P., Ridker, P. M., and Maseri, A. (2002) Inflammation and atherosclerosis. Circulation 105, 1135-1143
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 10
    • 17144419252 scopus 로고    scopus 로고
    • Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice
    • Zhou, J., Lhotak, S., Hilditch, B. A., and Austin, R. C. (2005) Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 111, 1814-1821
    • (2005) Circulation , vol.111 , pp. 1814-1821
    • Zhou, J.1    Lhotak, S.2    Hilditch, B.A.3    Austin, R.C.4
  • 11
    • 0347285295 scopus 로고    scopus 로고
    • A trip to the ER: Coping with stress
    • Rutkowski, D. T., and Kaufman, R. J. (2004) A trip to the ER: coping with stress. Trends Cell Biol. 14, 20-28
    • (2004) Trends Cell Biol. , vol.14 , pp. 20-28
    • Rutkowski, D.T.1    Kaufman, R.J.2
  • 12
    • 33644858343 scopus 로고    scopus 로고
    • The unfolded protein response: A stress signaling pathway critical for health and disease
    • Zhang, K., and Kaufman, R. J. (2006) The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 66, S102-109
    • (2006) Neurology , vol.66
    • Zhang, K.1    Kaufman, R.J.2
  • 14
    • 0038080911 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: Role of ATP binding site in suppression of caspase-7 activation
    • Reddy, R. K., Mao, C., Baumeister, P., Austin, R. C., Kaufman, R. J., and Lee, A. S. (2003) Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J. Biol. Chem. 278, 20915-20924
    • (2003) J. Biol. Chem. , vol.278 , pp. 20915-20924
    • Reddy, R.K.1    Mao, C.2    Baumeister, P.3    Austin, R.C.4    Kaufman, R.J.5    Lee, A.S.6
  • 15
    • 33644790277 scopus 로고    scopus 로고
    • Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: Implications in atherogenesis
    • Dickhout, J. G., Hossain, G. S., Pozza, L. M., Zhou, J., Lhotak, S., and Austin, R. C. (2005) Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler. Thromb. Vasc. Biol. 25, 2623-2629
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2623-2629
    • Dickhout, J.G.1    Hossain, G.S.2    Pozza, L.M.3    Zhou, J.4    Lhotak, S.5    Austin, R.C.6
  • 16
    • 0037497965 scopus 로고    scopus 로고
    • Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice
    • Zhou, J., Moller, J., Ritskes-Hoitinga, M., Larsen, M. L., Austin, R. C., and Falk, E. (2003) Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice. Atherosclerosis 168, 255-262
    • (2003) Atherosclerosis , vol.168 , pp. 255-262
    • Zhou, J.1    Moller, J.2    Ritskes-Hoitinga, M.3    Larsen, M.L.4    Austin, R.C.5    Falk, E.6
  • 17
    • 0035573652 scopus 로고    scopus 로고
    • Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice
    • Zhou, J., Moller, J., Danielsen, C. C., Bentzon, J., Ravn, H. B., Austin, R. C., and Falk, E. (2001) Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 21, 1470-1476
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1470-1476
    • Zhou, J.1    Moller, J.2    Danielsen, C.C.3    Bentzon, J.4    Ravn, H.B.5    Austin, R.C.6    Falk, E.7
  • 18
    • 0037926903 scopus 로고    scopus 로고
    • Hyperhomocysteinemia accelerates atherosclerosis in cystathionine β-synthase and apolipoprotein e double knock-out mice with and without dietary perturbation
    • Wang, H., Jiang, X., Yang, F., Gaubatz, J. W., Ma, L., Magera, M. J., Yang, X., Berger, P. B., Durante, W., Pownall, H. J., and Schafer, A. I. (2003) Hyperhomocysteinemia accelerates atherosclerosis in cystathionine β-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation. Blood 101, 3901-3907
    • (2003) Blood , vol.101 , pp. 3901-3907
    • Wang, H.1    Jiang, X.2    Yang, F.3    Gaubatz, J.W.4    Ma, L.5    Magera, M.J.6    Yang, X.7    Berger, P.B.8    Durante, W.9    Pownall, H.J.10    Schafer, A.I.11
  • 20
    • 0033533527 scopus 로고    scopus 로고
    • Homocyst(e)ine and cardiovascular disease: A critical review of the epidemiologic evidence
    • Eikelboom, J. W., Lonn, E., Genest, J., Jr., Hankey, G., and Yusuf, S. (1999) Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence. Ann. Intern. Med. 131, 363-375
    • (1999) Ann. Intern. Med. , vol.131 , pp. 363-375
    • Eikelboom, J.W.1    Lonn, E.2    Genest Jr., J.3    Hankey, G.4    Yusuf, S.5
  • 21
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
    • Boushey, C. J., Beresford, S. A., Omenn, G. S., and Motulsky, A. G. (1995) A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 274, 1049-1057
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 22
    • 0036732030 scopus 로고    scopus 로고
    • Cholesterol in health and disease
    • Tabas, I. (2002) Cholesterol in health and disease. J. Clin. Invest. 110, 583-590
    • (2002) J. Clin. Invest. , vol.110 , pp. 583-590
    • Tabas, I.1
  • 24
    • 0037023726 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP
    • Gotoh, T., Oyadomari, S., Mori, K., and Mori, M. (2002) Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP. J. Biol. Chem. 277, 12343-12350
    • (2002) J. Biol. Chem. , vol.277 , pp. 12343-12350
    • Gotoh, T.1    Oyadomari, S.2    Mori, K.3    Mori, M.4
  • 25
    • 0035812912 scopus 로고    scopus 로고
    • Induction of CHOP and apoptosis by nitric oxide in p53-deficient microglial cells
    • Kawahara, K., Oyadomari, S., Gotoh, T., Kohsaka, S., Nakayama, H., and Mori, M. (2001) Induction of CHOP and apoptosis by nitric oxide in p53-deficient microglial cells. FEBS Lett. 506, 135-139
    • (2001) FEBS Lett. , vol.506 , pp. 135-139
    • Kawahara, K.1    Oyadomari, S.2    Gotoh, T.3    Kohsaka, S.4    Nakayama, H.5    Mori, M.6
  • 28
    • 43049176549 scopus 로고    scopus 로고
    • Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: A randomized trial
    • Albert, C. M., Cook, N. R., Gaziano, J. M., Zaharris, E., Mac- Fadyen, J., Danielson, E., Buring, J. E., and Manson, J. E. (2008) Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial. JAMA 299, 2027-2036
    • (2008) JAMA , vol.299 , pp. 2027-2036
    • Albert, C.M.1    Cook, N.R.2    Gaziano, J.M.3    Zaharris, E.4    Mac-Fadyen, J.5    Danielson, E.6    Buring, J.E.7    Manson, J.E.8
  • 29
    • 77953867844 scopus 로고    scopus 로고
    • Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: A randomized trial
    • Armitage, J. M., Bowman, L., Clarke, R. J., Wallendszus, K., Bulbulia, R., Rahimi, K., Haynes, R., Parish, S., Sleight, P., Peto, R., and Collins, R. (2010) Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial. JAMA 303, 2486-2494
    • (2010) JAMA , vol.303 , pp. 2486-2494
    • Armitage, J.M.1    Bowman, L.2    Clarke, R.J.3    Wallendszus, K.4    Bulbulia, R.5    Rahimi, K.6    Haynes, R.7    Parish, S.8    Sleight, P.9    Peto, R.10    Collins, R.11
  • 30
    • 65349135431 scopus 로고    scopus 로고
    • Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP
    • Thorp, E., Li, G., Seimon, T. A., Kuriakose, G., Ron, D., and Tabas, I. (2009) Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. Cell Metab. 9, 474-481
    • (2009) Cell Metab. , vol.9 , pp. 474-481
    • Thorp, E.1    Li, G.2    Seimon, T.A.3    Kuriakose, G.4    Ron, D.5    Tabas, I.6
  • 31
    • 0142061067 scopus 로고    scopus 로고
    • Increasing the yield of human mononuclear cells and low serum conditions for in vitro generation of macrophages with M-CSF
    • Plesner, A. (2003) Increasing the yield of human mononuclear cells and low serum conditions for in vitro generation of macrophages with M-CSF. J. Immunol. Methods 279, 287-295
    • (2003) J. Immunol. Methods , vol.279 , pp. 287-295
    • Plesner, A.1
  • 33
    • 0034529396 scopus 로고    scopus 로고
    • Establishment of fluorescein diacetate and ethidium bromide (FDAEB) assay for quality assessment of isolated islets
    • Miyamoto, M., Morimoto, Y., Nozawa, Y., Balamurugan, A., Xu, B., and Inoue, K. (2000) Establishment of fluorescein diacetate and ethidium bromide (FDAEB) assay for quality assessment of isolated islets. Cell Transplant. 9, 681-686
    • (2000) Cell Transplant. , vol.9 , pp. 681-686
    • Miyamoto, M.1    Morimoto, Y.2    Nozawa, Y.3    Balamurugan, A.4    Xu, B.5    Inoue, K.6
  • 34
    • 0029998236 scopus 로고    scopus 로고
    • Biotin- or digoxigenin-conjugated nucleotides bind to matrix vesicles in atherosclerotic plaques
    • Kockx, M. M., Muhring, J., Bortier, H., De Meyer, G. R., and Jacob, W. (1996) Biotin- or digoxigenin-conjugated nucleotides bind to matrix vesicles in atherosclerotic plaques. Am. J. Pathol. 148, 1771-1777
    • (1996) Am. J. Pathol. , vol.148 , pp. 1771-1777
    • Kockx, M.M.1    Muhring, J.2    Bortier, H.3    De Meyer, G.R.4    Jacob, W.5
  • 36
    • 42349106840 scopus 로고    scopus 로고
    • Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors
    • Wang, Y. C., Kulp, S. K., Wang, D., Yang, C. C., Sargeant, A. M., Hung, J. H., Kashida, Y., Yamaguchi, M., Chang, G. D., and Chen, C. S. (2008) Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors. Cancer Res. 68, 2820-2830
    • (2008) Cancer Res. , vol.68 , pp. 2820-2830
    • Wang, Y.C.1    Kulp, S.K.2    Wang, D.3    Yang, C.C.4    Sargeant, A.M.5    Hung, J.H.6    Kashida, Y.7    Yamaguchi, M.8    Chang, G.D.9    Chen, C.S.10
  • 37
    • 68949214283 scopus 로고    scopus 로고
    • The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response
    • Basseri, S., Lhotak, S., Sharma, A. M., and Austin, R. C. (2009) The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response. J. Lipid Res. 50, 2486-2501
    • (2009) J. Lipid Res. , vol.50 , pp. 2486-2501
    • Basseri, S.1    Lhotak, S.2    Sharma, A.M.3    Austin, R.C.4
  • 38
    • 34447550255 scopus 로고    scopus 로고
    • Managing and exploiting stress in the antibody factory
    • Cenci, S., and Sitia, R. (2007) Managing and exploiting stress in the antibody factory. FEBS Lett. 581, 3652-3657
    • (2007) FEBS Lett. , vol.581 , pp. 3652-3657
    • Cenci, S.1    Sitia, R.2
  • 39
    • 0037930861 scopus 로고    scopus 로고
    • Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin- binding protein (GRP78/ BiP) inhibits tissue factor procoagulant activity
    • Watson, L. M., Chan, A. K., Berry, L. R., Li, J., Sood, S. K., Dickhout, J. G., Xu, L., Werstuck, G. H., Bajzar, L., Klamut, H. J., and Austin, R. C. (2003) Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin- binding protein (GRP78/ BiP) inhibits tissue factor procoagulant activity. J. Biol. Chem. 278, 17438-17447
    • (2003) J. Biol. Chem. , vol.278 , pp. 17438-17447
    • Watson, L.M.1    Chan, A.K.2    Berry, L.R.3    Li, J.4    Sood, S.K.5    Dickhout, J.G.6    Xu, L.7    Werstuck, G.H.8    Bajzar, L.9    Klamut, H.J.10    Austin, R.C.11
  • 40
    • 35448946819 scopus 로고    scopus 로고
    • Role of endoplasmic reticulum calcium disequilibria in the mechanism of homocysteine-induced ER stress
    • Dickhout, J. G., Sood, S. K., and Austin, R. C. (2007) Role of endoplasmic reticulum calcium disequilibria in the mechanism of homocysteine-induced ER stress. Antioxid. Redox Signal. 9, 1863-1873
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 1863-1873
    • Dickhout, J.G.1    Sood, S.K.2    Austin, R.C.3
  • 41
    • 0037384175 scopus 로고    scopus 로고
    • The stressful road to antibody secretion
    • Ma, Y., and Hendershot, L. M. (2003) The stressful road to antibody secretion. Nat. Immunol. 4, 310-311
    • (2003) Nat. Immunol. , vol.4 , pp. 310-311
    • Ma, Y.1    Hendershot, L.M.2
  • 42
    • 0037385313 scopus 로고    scopus 로고
    • Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
    • Iwakoshi, N. N., Lee, A. H., Vallabhajosyula, P., Otipoby, K. L., Rajewsky, K., and Glimcher, L. H. (2003) Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat. Immunol. 4, 321-329
    • (2003) Nat. Immunol. , vol.4 , pp. 321-329
    • Iwakoshi, N.N.1    Lee, A.H.2    Vallabhajosyula, P.3    Otipoby, K.L.4    Rajewsky, K.5    Glimcher, L.H.6
  • 43
    • 10444226462 scopus 로고    scopus 로고
    • ER stress and the unfolded protein response
    • Schroder, M., and Kaufman, R. J. (2005) ER stress and the unfolded protein response. Mutat. Res. 569, 29-63
    • (2005) Mutat. Res. , vol.569 , pp. 29-63
    • Schroder, M.1    Kaufman, R.J.2
  • 44
    • 0037332128 scopus 로고    scopus 로고
    • Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion
    • Van Anken, E., Romijn, E. P., Maggioni, C., Mezghrani, A., Sitia, R., Braakman, I., and Heck, A. J. (2003) Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. Immunity 18, 243-253
    • (2003) Immunity , vol.18 , pp. 243-253
    • Van Anken, E.1    Romijn, E.P.2    Maggioni, C.3    Mezghrani, A.4    Sitia, R.5    Braakman, I.6    Heck, A.J.7
  • 45
    • 0030698129 scopus 로고    scopus 로고
    • A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells
    • Brewer, J. W., Cleveland, J. L., and Hendershot, L. M. (1997) A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells. EMBO J. 16, 7207-7216
    • (1997) EMBO J. , vol.16 , pp. 7207-7216
    • Brewer, J.W.1    Cleveland, J.L.2    Hendershot, L.M.3
  • 46
    • 0024465760 scopus 로고
    • Increased circulating CSF-1 (M-CSF) in myeloproliferative disease: Association with myeloid metaplasia and peripheral bone marrow extension
    • Gilbert, H. S., Praloran, V., and Stanley, E. R. (1989) Increased circulating CSF-1 (M-CSF) in myeloproliferative disease: association with myeloid metaplasia and peripheral bone marrow extension. Blood 74, 1231-1234
    • (1989) Blood , vol.74 , pp. 1231-1234
    • Gilbert, H.S.1    Praloran, V.2    Stanley, E.R.3
  • 47
    • 30044448462 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 in immunity and inflammation
    • Chitu, V., and Stanley, E. R. (2006) Colony-stimulating factor-1 in immunity and inflammation. Curr. Opin. Immunol. 18, 39-48
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 39-48
    • Chitu, V.1    Stanley, E.R.2
  • 48
    • 0026536343 scopus 로고
    • Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis
    • Clinton, S. K., Underwood, R., Hayes, L., Sherman, M. L., Kufe, D. W., and Libby, P. (1992) Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis. Am. J. Pathol. 140, 301-316
    • (1992) Am. J. Pathol. , vol.140 , pp. 301-316
    • Clinton, S.K.1    Underwood, R.2    Hayes, L.3    Sherman, M.L.4    Kufe, D.W.5    Libby, P.6
  • 49
    • 0026514827 scopus 로고
    • Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans
    • Rosenfeld, M. E., Yla-Herttuala, S., Lipton, B. A., Ord, V. A., Witztum, J. L., and Steinberg, D. (1992) Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans. Am. J. Pathol. 140, 291-300
    • (1992) Am. J. Pathol. , vol.140 , pp. 291-300
    • Rosenfeld, M.E.1    Yla-Herttuala, S.2    Lipton, B.A.3    Ord, V.A.4    Witztum, J.L.5    Steinberg, D.6
  • 50
    • 22144474008 scopus 로고    scopus 로고
    • Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin
    • Misra, U. K., and Pizzo, S. V. (2005) Up-regulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin. J. Leukoc. Biol. 78, 187-197
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 187-197
    • Misra, U.K.1    Pizzo, S.V.2
  • 51
    • 0028958712 scopus 로고
    • Expression and phosphorylation of BiP/GRP78, a molecular chaperone in the endoplasmic reticulum, during the differentiation of a mouse myeloblastic cell line
    • Nakai, A., Kawatani, T., Ohi, S., Kawasaki, H., Yoshimori, T., Tashiro, Y., Miyata, Y., Yahara, I., Satoh, M., and Nagata, K. (1995) Expression and phosphorylation of BiP/GRP78, a molecular chaperone in the endoplasmic reticulum, during the differentiation of a mouse myeloblastic cell line. Cell Struct. Funct. 20, 33-39
    • (1995) Cell Struct. Funct. , vol.20 , pp. 33-39
    • Nakai, A.1    Kawatani, T.2    Ohi, S.3    Kawasaki, H.4    Yoshimori, T.5    Tashiro, Y.6    Miyata, Y.7    Yahara, I.8    Satoh, M.9    Nagata, K.10
  • 53
    • 0032978142 scopus 로고    scopus 로고
    • The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo
    • Guevara, N. V., Kim, H. S., Antonova, E. I., and Chan, L. (1999) The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo. Nat. Med. 5, 335-339
    • (1999) Nat. Med. , vol.5 , pp. 335-339
    • Guevara, N.V.1    Kim, H.S.2    Antonova, E.I.3    Chan, L.4
  • 54
    • 11144220581 scopus 로고    scopus 로고
    • Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice
    • Liu, J., Thewke, D. P., Su, Y. R., Linton, M. F., Fazio, S., and Sinensky, M. S. (2005) Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice. Arterioscler. Thromb. Vasc. Biol. 25, 174-179
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 174-179
    • Liu, J.1    Thewke, D.P.2    Su, Y.R.3    Linton, M.F.4    Fazio, S.5    Sinensky, M.S.6
  • 56
    • 0031054643 scopus 로고    scopus 로고
    • Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins
    • Morris, J. A., Dorner, A. J., Edwards, C. A., Hendershot, L. M., and Kaufman, R. J. (1997) Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins. J. Biol. Chem. 272, 4327-4334
    • (1997) J. Biol. Chem. , vol.272 , pp. 4327-4334
    • Morris, J.A.1    Dorner, A.J.2    Edwards, C.A.3    Hendershot, L.M.4    Kaufman, R.J.5
  • 60
    • 0032853093 scopus 로고    scopus 로고
    • Macrophage colony-stimulating factor reduces tert-butyl hydroperoxide induced oxidative injury to monocytes/macrophages
    • Pang, Z. J., Zhou, M., Chen, Y., and Wan, J. (1999) Macrophage colony-stimulating factor reduces tert-butyl hydroperoxide induced oxidative injury to monocytes/macrophages. Atherosclerosis 147, 33-40
    • (1999) Atherosclerosis , vol.147 , pp. 33-40
    • Pang, Z.J.1    Zhou, M.2    Chen, Y.3    Wan, J.4
  • 61
    • 0029079926 scopus 로고
    • Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E
    • Smith, J. D., Trogan, E., Ginsberg, M., Grigaux, C., Tian, J., and Miyata, M. (1995) Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. Proc. Natl. Acad. Sci. U. S. A. 92, 8264-8268
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 8264-8268
    • Smith, J.D.1    Trogan, E.2    Ginsberg, M.3    Grigaux, C.4    Tian, J.5    Miyata, M.6
  • 64
    • 70350435712 scopus 로고    scopus 로고
    • Macrophage apoptosis in advanced atherosclerosis
    • Tabas, I., Seimon, T., Timmins, J., Li, G., and Lim, W. (2009) Macrophage apoptosis in advanced atherosclerosis. Ann. N. Y. Acad. Sci. 1173(Suppl. 1), E40-E45
    • (2009) Ann. N. Y. Acad. Sci. , vol.1173 , Issue.SUPPL. 1
    • Tabas, I.1    Seimon, T.2    Timmins, J.3    Li, G.4    Lim, W.5
  • 66
    • 27644537437 scopus 로고    scopus 로고
    • Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: The importance of lesion stage and phagocytic efficiency
    • Tabas, I. (2005) Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arterioscler. Thromb. Vasc. Biol. 25, 2255-2264
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , pp. 2255-2264
    • Tabas, I.1
  • 67
    • 34948901308 scopus 로고    scopus 로고
    • Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome - A balancing act between plaque stability and rupture
    • Dickhout, J. G., Colgan, S. M., Lhotak, S., and Austin, R. C. (2007) Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome - a balancing act between plaque stability and rupture. Circulation 116, 1214-1216
    • (2007) Circulation , vol.116 , pp. 1214-1216
    • Dickhout, J.G.1    Colgan, S.M.2    Lhotak, S.3    Austin, R.C.4


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