Glomerular VEGF resistance induced by PKCδ/SHP-1 activation and contribution to diabetic nephropathy

FASEB Journal

Volumn 26, Issue 7, 2012, Pages 2963-2974

  Mima, Akira ^a   Kitada, Munehiro ^a   Geraldes, Pedro ^b   Li, Qian ^a   Matsumoto, Motonobu ^a   Mizutani, Koji ^a   Qi, Weier ^a   Li, Chenzhong ^a   Leitges, Michael ^c   Rask Madsen, Christian ^a   King, George L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITÉ DE SHERBROOKE   (Canada)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Hyperglycemia; Podocyte apoptosis; VEGFR 2

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTIOXIDANT; GLUCOSE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C DELTA; PROTEIN TYROSINE PHOSPHATASE SHP; SN 50; VASCULOTROPIN;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; GLOMERULUS; GLOMERULUS FILTRATION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; DIABETIC NEPHROPATHIES; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FEMALE; GLUCOSE; KIDNEY GLOMERULUS; MALE; MICE; MICE, KNOCKOUT; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PODOCYTES; PROTEIN KINASE C-DELTA; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

MUS; RATTUS; RODENTIA;

EID: 84863215195     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-202994     Document Type: Article

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