The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis

Nature Medicine

Volumn 12, Issue 5, 2006, Pages 549-556

  Dubois, Marie Julie ^a   Bergeron, Sébastien ^a   Kim, Hyo Jeong ^b,c   Dombrowski, Luce ^a   Perreault, Mylène ^a   Fournès, Bénédicte ^d   Faure, Robert ^a   Olivier, Martin ^e   Beauchemin, Nicole ^d   Shulman, Gerald I ^b,f   Siminovitch, Katherine A ^g   Kim, Jason K ^b,c   Marette, André ^a  

^a LAVAL UNIVERSITY   (Canada)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e MCGILL UNIVERSITY   (Canada)

^f Howard Hughes Medical Institute   (Canada)

^g MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PROTEIN TYROSINE PHOSPHATASE SHP 1; RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REGULATION; GENE SILENCING; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; HEMATOPOIETIC CELL; IN VITRO STUDY; INSULIN CLEARANCE; INSULIN SENSITIVITY; LIVER CELL; LIVER CLEARANCE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOOD GLUCOSE; CARCINOEMBRYONIC ANTIGEN; GENE SILENCING; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-AKT; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 33646551477     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1397     Document Type: Article

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