Ascochlorin inhibits growth factor-induced HIF-1α activation and tumor-angiogenesis through the suppression of EGFR/ERK/p70S6K signaling pathway in human cervical carcinoma cells

Journal of Cellular Biochemistry

Volumn 113, Issue 4, 2012, Pages 1302-1313

  Jeong, Ji Hak ^a   Jeong, Yun Jeong ^a   Cho, Hyun Ji ^a   Shin, Jae Moon ^a   Kang, Jeong Han ^a   Park, Kwan Kyu ^a   Park, Yoon Yub ^a   Chung, Il Kyung ^a   Chang, Hyeun Wook ^b   Magae, Junji ^c   Kang, Shin Sung ^d   Chang, Young Chae ^a  

^a Catholic University of Daegu   (South Korea)

^b Yeungnam University   (South Korea)

^c CENTRAL RESEARCH INSTITUTE OF ELECTRIC POWER INDUSTRY   (Japan)

^d University of Ulsan   (South Korea)

Author keywords

ANGIOGENESIS; ASCOCHLORIN; EGFR; HIF 1 ; VEGF

Indexed keywords

ANTINEOPLASTIC AGENT; ASCOCHLORIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENOL DERIVATIVE; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSITION ELEMENT; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UTERINE CERVIX CARCINOMA;

ALKENES; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE, TUMOR; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOVASCULARIZATION, PATHOLOGIC; PHENOLS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UTERINE CERVICAL NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ASCOCHYTA; FUNGI;

EID: 84863115594     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24001     Document Type: Article

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