Short-duration treatment with the calpain inhibitor mdl-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury

Journal of Neurotrauma

Volumn 29, Issue 2, 2012, Pages 445-451

  Ma, Marek ^a,b   Li, Luchuan ^a,b,c   Wang, Xinran ^a,b   Bull, Diana L ^a,b   Shofer, Frances S ^a   Meaney, David F ^d   Neumar, Robert W ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c SHANDONG UNIVERSITY   (China)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

adult brain injury; animal studies; axonal injury; axonal transport; traumatic brain injury

Indexed keywords

[1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER; CALPAIN; FLUOROGOLD; FODRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXONAL INJURY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; NONHUMAN; OPTIC NERVE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; RAT; RETINA GANGLION CELL; RETROGRADE NERVE FIBER TRANSPORT; TRAUMATIC AXONAL INJURY; TREATMENT DURATION;

ANIMALS; AXONAL TRANSPORT; CALPAIN; CYSTEINE PROTEINASE INHIBITORS; DIFFUSE AXONAL INJURY; DIPEPTIDES; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; MALE; NEUROPROTECTIVE AGENTS; RATS; RATS, LONG-EVANS; TIME FACTORS; TREATMENT FAILURE;

EID: 84863078886     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.2060     Document Type: Article

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