A pharmacological analysis of the neuroprotective efficacy of the brain-and cell-permeable calpain inhibitor MDL-28170 in the mouse controlled cortical impact traumatic brain injury model

Journal of Neurotrauma

Volumn 27, Issue 12, 2010, Pages 2233-2243

  Thompson, Stephanie N ^a   Carrico, Kimberly M ^a   Mustafa, Ayman G ^a,b   Bains, Mona ^a   Hall, Edward D ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

Author keywords

calpain; controlled cortical impact; cytoskeleton; neurodegeneration; traumatic brain injury

Indexed keywords

[1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER; FODRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXONAL INJURY; BLOOD BRAIN BARRIER; BRAIN CORTEX; CELL MEMBRANE PERMEABILITY; DEGRADATION; DOSE RESPONSE; DRUG EFFECT; DRUG HALF LIFE; HIPPOCAMPUS; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; SILVER STAINING; TRAUMATIC BRAIN INJURY;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN INJURIES; CALPAIN; CEREBRAL CORTEX; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; MALE; MICE; NERVE DEGENERATION; NEURONS; SPECTRIN;

EID: 78650082396     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2010.1474     Document Type: Article

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