Biodegradable nanoparticles of mPEG-PLGA-PLL triblock copolymers as novel non-viral vectors for improving siRNA delivery and gene silencing

International Journal of Molecular Sciences

Volumn 13, Issue 1, 2012, Pages 516-533

  Du, Jing ^a   Sun, Ying ^b   Shi, Qiu Sheng ^a   Liu, Pei Feng ^b   Zhu, Ming Jie ^b   Wang, Chun Hui ^c   Du, Lian Fang ^a   Duan, You Rong ^b  

^a SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Sino American United Biotechnology Institute Co Ltd   (China)

Author keywords

Gene silencing; GFP; Nanoparticles; PLGA; PLL; SiRNA delivery

Indexed keywords

COPOLYMER; GREEN FLUORESCENT PROTEIN; LIPOFECTAMINE; MONOMETHOXYPOLY(ETHYLENE GLYCOL) POLY(LACTIC CO GLYCOLIC ACID) POLYLYSINE TRIBLOCK COPOLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BIOMATERIAL; CARBOCYANINE; CYANINE DYE 3; DRUG CARRIER; LIPID; MACROGOL DERIVATIVE; NANOPARTICLE; POLY(D,L-LACTIC-CO-GLYCOLIC ACID)-METHOXY-POLY(ETHYLENEGLYCOL) COPOLYMER; POLYGLACTIN;

ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; ENCAPSULATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MORPHOLOGY; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SURFACE CHARGE; ZETA POTENTIAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; METABOLISM; RNA INTERFERENCE; TOXICITY; TUMOR CELL LINE;

BIOCOMPATIBLE MATERIALS; CARBOCYANINES; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; HUMANS; LIPIDS; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLACTIN 910; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84863017894     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13010516     Document Type: Article

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