Novel reducible linear L-lysine-modified copolymers as efficient nonviral vectors

Journal of Controlled Release

Volumn 143, Issue 3, 2010, Pages 326-334

  Nounou, Mohamed Ismail ^a   Emmanouil, Kalyopy ^a   Chung, Samuel ^a   Pham, Thu ^a   Lu, Zhuoyuan ^a   Bikram, Malavosklish ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

Biodegradable polymers; Bioreducible polymers; Lysine; Nonviral gene delivery; Transfection efficiency

Indexed keywords

BIOCOMPATIBLE POLYMER; BIOREDUCIBLE POLYMER; CLINICAL TRANSLATION; DITHIOTHREITOL; GEL-RETARDATION ASSAY; GENE CARRIER; GENE DELIVERY SYSTEMS; HIGH MOLECULAR WEIGHT; L-LYSINE; LUCIFERASE ASSAYS; MCF-7 CELLS; NON-VIRAL GENE DELIVERY; NONVIRAL; NONVIRAL VECTORS; POLY-L-LYSINE; POLYDISPERSITY INDICES; POLYPLEX STABILITY; POLYPLEXES; TRANSFECTION EFFICIENCY;

AMINO ACIDS; ASSAYS; COPOLYMERIZATION; COPOLYMERS; DNA; GELS; GENE TRANSFER; GENES; NUCLEIC ACIDS; POLYDISPERSITY; SULFUR COMPOUNDS; SYNTHESIS (CHEMICAL);

BIODEGRADABLE POLYMERS;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; COPOLYMER; DEOXYRIBONUCLEASE I; DITHIOTHREITOL; DNA; LUCIFERASE; LYSINE; POLYLYSINE;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CELL LINE; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DISPERSION; FLUORESCENCE MICROSCOPY; GEL PERMEATION CHROMATOGRAPHY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; ZETA POTENTIAL;

BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; DNA; HUMANS; LYSINE; OXIDATION-REDUCTION; PLASMIDS; POLYMERS; TRANSFECTION;

EID: 77952236935     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.12.032     Document Type: Article

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