-
2
-
-
0028020515
-
Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of post occlusion intra-arterial administration
-
Bartus R. T., Hayward N. J., Elliott P. J., Sawyer S. D., Baker K. L., Dean R. L., Akiyama B. S., Straub J. A., Harbeson S. L., Li Z., and Powers J. (1994) Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of post occlusion intra-arterial administration. Stroke 25, 2265-2270.
-
(1994)
Stroke
, vol.25
, pp. 2265-2270
-
-
Bartus, R.T.1
Hayward, N.J.2
Elliott, P.J.3
Sawyer, S.D.4
Baker, K.L.5
Dean, R.L.6
Akiyama, B.S.7
Straub, J.A.8
Harbeson, S.L.9
Li, Z.10
Powers, J.11
-
3
-
-
0028850474
-
Time-related neuronal changes following middle cerebral artery occlusion: Implications for therapeutic intervention and the role of calpain
-
Bartus R. T., Dean R. L., Cavanaugh K., Eveleth D., Carriero D. L., and Lynch G. (1995) Time-related neuronal changes following middle cerebral artery occlusion: implications for therapeutic intervention and the role of calpain. J. Cereb. Blood Flow Metab. 15, 969-979.
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 969-979
-
-
Bartus, R.T.1
Dean, R.L.2
Cavanaugh, K.3
Eveleth, D.4
Carriero, D.L.5
Lynch, G.6
-
4
-
-
0029015969
-
Delayed antagonism of calpain reduces excitotoxicity in cultured neurons
-
Brorson J. R., Marcucilli C. J., and Miller R. J. (1995) Delayed antagonism of calpain reduces excitotoxicity in cultured neurons. Stroke 26, 1259-1267.
-
(1995)
Stroke
, vol.26
, pp. 1259-1267
-
-
Brorson, J.R.1
Marcucilli, C.J.2
Miller, R.J.3
-
5
-
-
0028931596
-
Regional cerebral blood flow after controlled cortical impact in rats
-
Bryan R. M., Cherian L., and Robertson C. (1995) Regional cerebral blood flow after controlled cortical impact in rats. Anesth. Analg. 80, 687-695.
-
(1995)
Anesth. Analg.
, vol.80
, pp. 687-695
-
-
Bryan, R.M.1
Cherian, L.2
Robertson, C.3
-
6
-
-
0023753142
-
Calcium mediated neurotoxicity: Relationship to specific channel type and role in ischemic damage
-
Choi D. W. (1988) Calcium mediated neurotoxicity: relationship to specific channel type and role in ischemic damage. Trends Neurosci. 11, 465-469.
-
(1988)
Trends Neurosci.
, vol.11
, pp. 465-469
-
-
Choi, D.W.1
-
8
-
-
0028922688
-
Spatial memory deficits, increased phosphorylation of the transcription factor CREB and induction of the AP-1 complex following experimental brain injury
-
Dash P. K., Moore A. N., and Dixon C. E. (1994) Spatial memory deficits, increased phosphorylation of the transcription factor CREB and induction of the AP-1 complex following experimental brain injury. J. Neurosci. 15, 2030-2039.
-
(1994)
J. Neurosci.
, vol.15
, pp. 2030-2039
-
-
Dash, P.K.1
Moore, A.N.2
Dixon, C.E.3
-
9
-
-
0026062640
-
A controlled cortical impact model of traumatic brain injury in the rat
-
Dixon C. E., Clifton G. L., Lighthall J. W., Yaghmai A. A., and Hayes R. L. (1991) A controlled cortical impact model of traumatic brain injury in the rat. J. Neurosci. Methods 39, 253-262.
-
(1991)
J. Neurosci. Methods
, vol.39
, pp. 253-262
-
-
Dixon, C.E.1
Clifton, G.L.2
Lighthall, J.W.3
Yaghmai, A.A.4
Hayes, R.L.5
-
10
-
-
0026073804
-
Comparison of the autolyzed and unautolyzed forms of μ- and m-calpain from bovine skeletal muscle
-
Edmunds T., Nagainis P. A., Sathe S. K., Thompson V. F., and Goll D. E. (1991) Comparison of the autolyzed and unautolyzed forms of μ- and m-calpain from bovine skeletal muscle. Biochim. Biophys. Acta 1077, 197-208.
-
(1991)
Biochim. Biophys. Acta
, vol.1077
, pp. 197-208
-
-
Edmunds, T.1
Nagainis, P.A.2
Sathe, S.K.3
Thompson, V.F.4
Goll, D.E.5
-
11
-
-
0024365739
-
The role of excitatory amino acids and NMDA receptors in traumatic brain injury
-
Faden A. I., Dogmatic P., Panter S. S., and Vink R. (1989) The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244, 798-800.
-
(1989)
Science
, vol.244
, pp. 798-800
-
-
Faden, A.I.1
Dogmatic, P.2
Panter, S.S.3
Vink, R.4
-
13
-
-
0028793887
-
Axotomy induced axonal degeneration is mediated by calcium influx through ion-specific channels
-
George E. B., Glass J. D., and Griffin J. W. (1995) Axotomy induced axonal degeneration is mediated by calcium influx through ion-specific channels. J. Neurosci. 15, 6445-6452.
-
(1995)
J. Neurosci.
, vol.15
, pp. 6445-6452
-
-
George, E.B.1
Glass, J.D.2
Griffin, J.W.3
-
14
-
-
0002488233
-
2+-dependent proteinase system
-
Mellgren R. L. and Murachi T., eds, CRC Press, Boca Raton, Florida
-
2+-dependent proteinase system, in Intracellular Calcium-Dependent Proteolysis (Mellgren R. L. and Murachi T., eds), pp. 3-24. CRC Press, Boca Raton, Florida.
-
(1990)
Intracellular Calcium-Dependent Proteolysis
, pp. 3-24
-
-
Goll, D.E.1
Kleese, W.C.2
Okitani, A.3
Kumamoto, T.4
Cong, J.5
Kapprell, H.-P.6
-
15
-
-
0023000721
-
Distributions of calpains I and II in rat brain
-
Hamakubo T., Kannagi R., Murachi T., and Matus A. (1986) Distributions of calpains I and II in rat brain. J. Neurosci. 6, 3103-3111.
-
(1986)
J. Neurosci.
, vol.6
, pp. 3103-3111
-
-
Hamakubo, T.1
Kannagi, R.2
Murachi, T.3
Matus, A.4
-
16
-
-
0023792182
-
The calmodulin binding site in alpha fodrin is near the calcium-dependent-protease-I cleavage site
-
Harris A. S., Croall D. E., and Morrow J. S. (1988) The calmodulin binding site in alpha fodrin is near the calcium-dependent-protease-I cleavage site. J. Biol. Chem. 263, 15754-15761.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 15754-15761
-
-
Harris, A.S.1
Croall, D.E.2
Morrow, J.S.3
-
17
-
-
0024146867
-
Pretreatment with phencyclidine, and N-methyl-D-aspartate antagonist, attenuates long term behavioral deficits in the rat produced by traumatic brain injury
-
Hayes R. L., Jenkins L. K. W., and Lyeth B. G. (1988) Pretreatment with phencyclidine, and N-methyl-D-aspartate antagonist, attenuates long term behavioral deficits in the rat produced by traumatic brain injury. J. Neurotrauma 5, 259-274.
-
(1988)
J. Neurotrauma
, vol.5
, pp. 259-274
-
-
Hayes, R.L.1
Jenkins, L.K.W.2
Lyeth, B.G.3
-
18
-
-
0026518645
-
Neurotransmitter mediated mechanisms of traumatic brain injury
-
Hayes R. L., Jenkin L. K. W., and Lyeth B. G. (1992) Neurotransmitter mediated mechanisms of traumatic brain injury. J. Neurotrauma 9, 173-187.
-
(1992)
J. Neurotrauma
, vol.9
, pp. 173-187
-
-
Hayes, R.L.1
Jenkin, L.K.W.2
Lyeth, B.G.3
-
19
-
-
0028902692
-
Temporal response and effects of excitatory amino acid antagonism on microtubule associated protein 2 immunoreactivity following experimental brain injury in rats
-
Hicks R., Douglas S. H., and McIntosh T. K. (1995) Temporal response and effects of excitatory amino acid antagonism on microtubule associated protein 2 immunoreactivity following experimental brain injury in rats. Brain Res. 678, 151-160.
-
(1995)
Brain Res.
, vol.678
, pp. 151-160
-
-
Hicks, R.1
Douglas, S.H.2
McIntosh, T.K.3
-
20
-
-
0028098014
-
Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia
-
Hong S. C., Goto Y., Lanzino G., Soleau S., Kassell N. F., and Lee K. S. (1994a) Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia. Stroke 25, 663-669.
-
(1994)
Stroke
, vol.25
, pp. 663-669
-
-
Hong, S.C.1
Goto, Y.2
Lanzino, G.3
Soleau, S.4
Kassell, N.F.5
Lee, K.S.6
-
21
-
-
0028132284
-
Calcium activated proteolysis in rat neocortex induced by transient focal ischemia
-
Hong S. C., Lazino G., Goto S., Kang S. K., Schottler F., Kassell N. F., and Lee K. S. (1994b) Calcium activated proteolysis in rat neocortex induced by transient focal ischemia. Brain Res. 661, 43-50.
-
(1994)
Brain Res.
, vol.661
, pp. 43-50
-
-
Hong, S.C.1
Lazino, G.2
Goto, S.3
Kang, S.K.4
Schottler, F.5
Kassell, N.F.6
Lee, K.S.7
-
22
-
-
0025184647
-
Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats
-
Inuzuka T., Tamura A., Sato S., Kirino T., Toyoshima I., and Miyatake T. (1990) Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats. Brain Res. 526, 177-179.
-
(1990)
Brain Res.
, vol.526
, pp. 177-179
-
-
Inuzuka, T.1
Tamura, A.2
Sato, S.3
Kirino, T.4
Toyoshima, I.5
Miyatake, T.6
-
23
-
-
0025731595
-
Degradation of microtubule-associated protein 2 and spectrin by calpain: A comparative study
-
Johnson G. V. W., Litersky J. M., and Jope R. S. (1991) Degradation of microtubule-associated protein 2 and spectrin by calpain: a comparative study. J. Neurochem. 56, 1630-1638.
-
(1991)
J. Neurochem.
, vol.56
, pp. 1630-1638
-
-
Johnson, G.V.W.1
Litersky, J.M.2
Jope, R.S.3
-
24
-
-
0027256393
-
Alterations of a 200kDa neurofilament in the rat hippocampus after forebrain ischemia
-
Kaku Y., Yonekawa Y., Tsukahara T., Ogata N., Kimura T., and Taniguchi T. (1993) Alterations of a 200kDa neurofilament in the rat hippocampus after forebrain ischemia. J. Cereb. Blood Flow Metab. 13, 402-408.
-
(1993)
J. Cereb. Blood Flow Metab.
, vol.13
, pp. 402-408
-
-
Kaku, Y.1
Yonekawa, Y.2
Tsukahara, T.3
Ogata, N.4
Kimura, T.5
Taniguchi, T.6
-
25
-
-
0021912078
-
2+, and its effect on the neurofilament triplet
-
2+, and its effect on the neurofilament triplet. J. Neurosci. Res. 13, 391-403.
-
(1985)
J. Neurosci. Res.
, vol.13
, pp. 391-403
-
-
Kamakura, K.1
Ishiura, S.2
Suzuki, K.3
Sugita, H.4
Takaku, F.5
-
26
-
-
0029045236
-
Calpain inhibitors reduce depolarization induced loss of tau protein in primary septo-hippocampal cultures
-
Kampfl A., Whitson S. J., Zhao X., Posmantur R., Clifton G. L., and Hayes R. L. (1995) Calpain inhibitors reduce depolarization induced loss of tau protein in primary septo-hippocampal cultures. Neurosci. Lett. 194, 149-152.
-
(1995)
Neurosci. Lett.
, vol.194
, pp. 149-152
-
-
Kampfl, A.1
Whitson, S.J.2
Zhao, X.3
Posmantur, R.4
Clifton, G.L.5
Hayes, R.L.6
-
27
-
-
0030070664
-
Calpain inhibitors protect against depolarization induced neurofilament protein loss of septo-hippocampal neurons in culture
-
Kampfl A., Zhao X., Whitson S. J., Posmantur R., Dixon C. E., Yang K., Clilfton G. L., and Hayes R. L. (1996) Calpain inhibitors protect against depolarization induced neurofilament protein loss of septo-hippocampal neurons in culture. Eur. J. Neurosci. 8, 344-352.
-
(1996)
Eur. J. Neurosci.
, vol.8
, pp. 344-352
-
-
Kampfl, A.1
Zhao, X.2
Whitson, S.J.3
Posmantur, R.4
Dixon, C.E.5
Yang, K.6
Clilfton, G.L.7
Hayes, R.L.8
-
28
-
-
0025242563
-
Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury
-
Katayama Y., Becker D. P., Tamura T., and Hovda D. A. (1990) Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J. Neurosurg. 73, 889-900.
-
(1990)
J. Neurosurg.
, vol.73
, pp. 889-900
-
-
Katayama, Y.1
Becker, D.P.2
Tamura, T.3
Hovda, D.A.4
-
29
-
-
0025774025
-
Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo
-
Katayama Y., Kawamata T., Tamura T., Hovda D. A., Becker D. P., and Tsubokawa T. (1991) Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo. Brain Res. 558, 136-140.
-
(1991)
Brain Res.
, vol.558
, pp. 136-140
-
-
Katayama, Y.1
Kawamata, T.2
Tamura, T.3
Hovda, D.A.4
Becker, D.P.5
Tsubokawa, T.6
-
30
-
-
0022500962
-
2+ concentration in isolated hippocampal neurons
-
2+ concentration in isolated hippocampal neurons. Br. J. Pharmacol. 89, 191-199.
-
(1986)
Br. J. Pharmacol.
, vol.89
, pp. 191-199
-
-
Kudo, Y.1
Ogura, A.2
-
31
-
-
0025826867
-
Inhibition of proteolysis protects hippocampal neurons from ischemia
-
Lee K. S., Frank S., Vanderklish P., Arai A., and Lynch G. (1991) Inhibition of proteolysis protects hippocampal neurons from ischemia. Proc. Natl. Acad. Sci. USA 88, 7233-7237.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7233-7237
-
-
Lee, K.S.1
Frank, S.2
Vanderklish, P.3
Arai, A.4
Lynch, G.5
-
32
-
-
0028087618
-
Microtubule-associated protein 2 as an early indicator of ischemia-induced neurodegeneration in the gerbil forebrain
-
Matesic D. F. and Lin R. C. S. (1994) Microtubule-associated protein 2 as an early indicator of ischemia-induced neurodegeneration in the gerbil forebrain. J. Neurochem. 63, 1012-1020.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1012-1020
-
-
Matesic, D.F.1
Lin, R.C.S.2
-
35
-
-
0023485902
-
The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro
-
Murphy S. N., Thayer S. A., and Miller R. J. (1987) The effects of excitatory amino acids on intracellular calcium in single mouse striatal neurons in vitro. J. Neurosci. 7, 4145-4158.
-
(1987)
J. Neurosci.
, vol.7
, pp. 4145-4158
-
-
Murphy, S.N.1
Thayer, S.A.2
Miller, R.J.3
-
36
-
-
0026612609
-
Differential distribution of 68kD and 200kD neurofilament proteins in gerbil hippocampus and their early distributional changes following transient forebrain ischemia
-
Nakamura M., Araki M., Oguro K., and Masuzawa T. (1992) Differential distribution of 68kD and 200kD neurofilament proteins in gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Exp. Brain Res. 89, 31-39.
-
(1992)
Exp. Brain Res.
, vol.89
, pp. 31-39
-
-
Nakamura, M.1
Araki, M.2
Oguro, K.3
Masuzawa, T.4
-
37
-
-
0029671032
-
Brain μ-calpain autolysis during global cerebral ischemia
-
Neumar R. W. Hagle S. M., DeGracia D. J., Krause G. S., and White B. C. (1996) Brain μ-calpain autolysis during global cerebral ischemia. J. Neurochem. 66, 421-424.
-
(1996)
J. Neurochem.
, vol.66
, pp. 421-424
-
-
Neumar, R.W.1
Hagle, S.M.2
DeGracia, D.J.3
Krause, G.S.4
White, B.C.5
-
38
-
-
0028238507
-
Brain ischemia decreases phosphatidylcholine-phospholipase D but not phosphatidylinositol-phospholipase C in rats
-
Nishida A., Emoto K., Shimizu M., Uozumi T., and Yamawaki S. (1994) Brain ischemia decreases phosphatidylcholine-phospholipase D but not phosphatidylinositol-phospholipase C in rats. Stroke 25, 1247-1251.
-
(1994)
Stroke
, vol.25
, pp. 1247-1251
-
-
Nishida, A.1
Emoto, K.2
Shimizu, M.3
Uozumi, T.4
Yamawaki, S.5
-
39
-
-
0025943790
-
Neurofilament phosphorylation: A new look at regulation and function
-
Nixon R. A. and Sihag R. K. (1991) Neurofilament phosphorylation: a new look at regulation and function. Trends Neurosci. 14, 501-506.
-
(1991)
Trends Neurosci.
, vol.14
, pp. 501-506
-
-
Nixon, R.A.1
Sihag, R.K.2
-
40
-
-
0025689162
-
Aluminum inhibits calpain-mediated proteolysis and induces human neurofilament proteins to form protein-resistant high molecular weight complexes
-
Nixon R. A., Clarke J. F., Logvinenko K. B., Tan M. K. H., Hoult M., and Grynspan F. (1990) Aluminum inhibits calpain-mediated proteolysis and induces human neurofilament proteins to form protein-resistant high molecular weight complexes. J. Neurochem. 55, 1950-1959.
-
(1990)
J. Neurochem.
, vol.55
, pp. 1950-1959
-
-
Nixon, R.A.1
Clarke, J.F.2
Logvinenko, K.B.3
Tan, M.K.H.4
Hoult, M.5
Grynspan, F.6
-
41
-
-
0028656522
-
Calcium activated neutral proteinase (calpain) system in aging and Alzheimer's disease
-
Nixon R. A., Saito K., Grynspan F., Griffin W. R., Katayama S., Honda T., Mohan P. S., and Shea T. B. (1994) Calcium activated neutral proteinase (calpain) system in aging and Alzheimer's disease. Ann. NY Acad. Sci. 747, 77-91.
-
(1994)
Ann. NY Acad. Sci.
, vol.747
, pp. 77-91
-
-
Nixon, R.A.1
Saito, K.2
Grynspan, F.3
Griffin, W.R.4
Katayama, S.5
Honda, T.6
Mohan, P.S.7
Shea, T.B.8
-
42
-
-
0027934386
-
Subcellular distribution of calpain and calpastatin immunoreactivity and fodrin proteolysis in rabbit hippocampus after hypoxia and glucocorticoid treatment
-
Ostwald K., Hayashi M., Nakamura M., and Kawashima S. (1994) Subcellular distribution of calpain and calpastatin immunoreactivity and fodrin proteolysis in rabbit hippocampus after hypoxia and glucocorticoid treatment. J. Neurochem. 63, 1069-1076.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1069-1076
-
-
Ostwald, K.1
Hayashi, M.2
Nakamura, M.3
Kawashima, S.4
-
43
-
-
0028135244
-
Neurofilament 68 and neurofilament 200 protein levels decrease after traumatic brain injury
-
Posmantur R., Hayes R. L., Dixon C. E., and Taft W. C. (1994) Neurofilament 68 and neurofilament 200 protein levels decrease after traumatic brain injury. J. Neurotrauma 11, 533-545.
-
(1994)
J. Neurotrauma
, vol.11
, pp. 533-545
-
-
Posmantur, R.1
Hayes, R.L.2
Dixon, C.E.3
Taft, W.C.4
-
44
-
-
0345431202
-
Multiple lines of evidence for prolonged calpain mediated proteolysis following traumatic brain injury (TBI)
-
Posmantur R. M., Kampfl A., Liu S. J., Clifton G. L., and Hayes R. L. (1995) Multiple lines of evidence for prolonged calpain mediated proteolysis following traumatic brain injury (TBI). (Abstr.) J. Neurotrauma 12, NC7, 972.
-
(1995)
J. Neurotrauma
, vol.12
, Issue.NC7
, pp. 972
-
-
Posmantur, R.M.1
Kampfl, A.2
Liu, S.J.3
Clifton, G.L.4
Hayes, R.L.5
-
45
-
-
0030063506
-
Cytoskeletal derangements of cortical neuronal processes three hours after traumatic brain injury in rats: An immunofluorescence study
-
Posmantur R. M., Kampfl A., Liu S. J., Heck K., Taft W. C., Clifton G. L., and Hayes R. L. (1996a) Cytoskeletal derangements of cortical neuronal processes three hours after traumatic brain injury in rats: an immunofluorescence study. J. Neuropathol. Exp. Neurol. 55, 68-80.
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 68-80
-
-
Posmantur, R.M.1
Kampfl, A.2
Liu, S.J.3
Heck, K.4
Taft, W.C.5
Clifton, G.L.6
Hayes, R.L.7
-
46
-
-
10144253093
-
A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental brain injury in the rat
-
in press
-
Posmantur R. M., Kampfl A., Siman R., Liu S. J., Zhao X., Clifton G. L., and Hayes R. L. (1996b) A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental brain injury in the rat. Neuroscience (in press).
-
(1996)
Neuroscience
-
-
Posmantur, R.M.1
Kampfl, A.2
Siman, R.3
Liu, S.J.4
Zhao, X.5
Clifton, G.L.6
Hayes, R.L.7
-
47
-
-
0029915040
-
Diminished microtubule associated protein 2 immunoreactivity following cortical impact injury
-
Posmantur R., Kampfl A., Taft W. C., Bhattacharjee M., Dixon C. E., Bao J., and Hayes R. L. (1996c) Diminished microtubule associated protein 2 immunoreactivity following cortical impact injury. J. Neurotrauma 13, 125-137.
-
(1996)
J. Neurotrauma
, vol.13
, pp. 125-137
-
-
Posmantur, R.1
Kampfl, A.2
Taft, W.C.3
Bhattacharjee, M.4
Dixon, C.E.5
Bao, J.6
Hayes, R.L.7
-
48
-
-
0027215039
-
Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo
-
Rami A. and Krieglstein J. (1993) Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo. Brain Res. 609, 67-70.
-
(1993)
Brain Res.
, vol.609
, pp. 67-70
-
-
Rami, A.1
Krieglstein, J.2
-
49
-
-
0028282502
-
Immunolocalization of μ calpain mediated spectrin degradation to vulnerable neurons in ischemic gerbil brain
-
Roberts-Lewis J. M., Savage M. J., Marcy V. R., Pinsker L. R., and Siman R. (1994) Immunolocalization of μ calpain mediated spectrin degradation to vulnerable neurons in ischemic gerbil brain. J. Neurosci. 14, 3934-3944.
-
(1994)
J. Neurosci.
, vol.14
, pp. 3934-3944
-
-
Roberts-Lewis, J.M.1
Savage, M.J.2
Marcy, V.R.3
Pinsker, L.R.4
Siman, R.5
-
50
-
-
9244230699
-
Calpain activation following experimental brain injury
-
Saatman K. E., Bozyczko-Coyne D., Siman R., Marcy V., Generalli A., and McIntosh T. K. (1995a) Calpain activation following experimental brain injury. (Abstr.) J. Neurotrauma 12, 138.
-
(1995)
J. Neurotrauma
, vol.12
, pp. 138
-
-
Saatman, K.E.1
Bozyczko-Coyne, D.2
Siman, R.3
Marcy, V.4
Generalli, A.5
McIntosh, T.K.6
-
51
-
-
10144242605
-
The calpain inhibitor AK295 improves outcome following experimental brain injury
-
Saatman K. E., Murai H., Bartus R. T., Hayward N., Perri B. R., and McIntosh T. K. (1995b) The calpain inhibitor AK295 improves outcome following experimental brain injury. (Abstr.) J. Neurotrauma 12, 481.
-
(1995)
J. Neurotrauma
, vol.12
, pp. 481
-
-
Saatman, K.E.1
Murai, H.2
Bartus, R.T.3
Hayward, N.4
Perri, B.R.5
McIntosh, T.K.6
-
52
-
-
0026542341
-
Autolytic transition of μ calpain upon activation as resolved by antibodies distinguishing between pre- and post-autolysis forms
-
Saido T. C., Nagao S., Shiramine M., Tsukaguchi M., Sorimachi H., Murofushi H., Tsuchiya T., Ito H., and Suzuki K. (1992) Autolytic transition of μ calpain upon activation as resolved by antibodies distinguishing between pre- and post-autolysis forms. J. Biochem. (Tokyo) 111, 81-86.
-
(1992)
J. Biochem. (Tokyo)
, vol.111
, pp. 81-86
-
-
Saido, T.C.1
Nagao, S.2
Shiramine, M.3
Tsukaguchi, M.4
Sorimachi, H.5
Murofushi, H.6
Tsuchiya, T.7
Ito, H.8
Suzuki, K.9
-
53
-
-
0028088153
-
Calpain: New perspectives in molecular diversity and physiological-pathological involvement
-
Saido T. C., Sorimachi H., and Suzuki K. (1994) Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J. 8, 814-822.
-
(1994)
FASEB J.
, vol.8
, pp. 814-822
-
-
Saido, T.C.1
Sorimachi, H.2
Suzuki, K.3
-
54
-
-
0027474051
-
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: A potential molecular basis for neuronal degeneration
-
Saito K. I., Elce J. S., Hamos J. E., and Nixon R. A. (1993) Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc. Natl. Acad. Sci. USA 90, 2628-2632.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2628-2632
-
-
Saito, K.I.1
Elce, J.S.2
Hamos, J.E.3
Nixon, R.A.4
-
55
-
-
0025099366
-
Inhibitory effects of di- and tripeptidyl aldehydes on calpains and cathepsins
-
Sasaki T., Kishi M., Saito M., Tanaka T., Higuchi N., Kominami E., Katunuma M., and Murachi T. (1990) Inhibitory effects of di- and tripeptidyl aldehydes on calpains and cathepsins. J. Enzym, Inhib. 2, 195-201.
-
(1990)
J. Enzym, Inhib.
, vol.2
, pp. 195-201
-
-
Sasaki, T.1
Kishi, M.2
Saito, M.3
Tanaka, T.4
Higuchi, N.5
Kominami, E.6
Katunuma, M.7
Murachi, T.8
-
56
-
-
0022272961
-
Calcium-activated proteolysis of intermediate filaments
-
Schlaepfer W. W. and Zimmerman U. J. P. (1985) Calcium-activated proteolysis of intermediate filaments. Ann. NY Acad. Sci. 455, 552-562.
-
(1985)
Ann. NY Acad. Sci.
, vol.455
, pp. 552-562
-
-
Schlaepfer, W.W.1
Zimmerman, U.J.P.2
-
57
-
-
0024347477
-
Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus
-
Seubert P., Lee K., and Lynch G. (1989) Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus. Brain Res. 492, 366-370.
-
(1989)
Brain Res.
, vol.492
, pp. 366-370
-
-
Seubert, P.1
Lee, K.2
Lynch, G.3
-
58
-
-
0024556434
-
Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: A unifying hypothesis
-
Siesjö B. K. and Bengtsson F. (1989) Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J. Cereb. Blood Flow Metab. 9, 127-140.
-
(1989)
J. Cereb. Blood Flow Metab.
, vol.9
, pp. 127-140
-
-
Siesjö, B.K.1
Bengtsson, F.2
-
59
-
-
0024020782
-
Excitatory amino acids activate μ calpain and induce structural protein breakdown in vivo
-
Siman R. and Noszek J. C. (1988) Excitatory amino acids activate μ calpain and induce structural protein breakdown in vivo. Neuron 1, 279-287.
-
(1988)
Neuron
, vol.1
, pp. 279-287
-
-
Siman, R.1
Noszek, J.C.2
-
60
-
-
0024363137
-
Calpain 1 activation is specifically related to excitatory amino acid induction of hippocampal damage
-
Siman R., Noszek J. C., and Kegerise C. (1989) Calpain 1 activation is specifically related to excitatory amino acid induction of hippocampal damage. J. Neurosci. 9, 1579-1590.
-
(1989)
J. Neurosci.
, vol.9
, pp. 1579-1590
-
-
Siman, R.1
Noszek, J.C.2
Kegerise, C.3
-
61
-
-
0023658410
-
Calcium-activated neutral protease and its endogenous inhibitor
-
Suzuki K., Imajoh S., Emori Y., Kawasaki H., Minami Y., and Ohno S. (1987) Calcium-activated neutral protease and its endogenous inhibitor. FEBS Lett. 220, 271-277.
-
(1987)
FEBS Lett.
, vol.220
, pp. 271-277
-
-
Suzuki, K.1
Imajoh, S.2
Emori, Y.3
Kawasaki, H.4
Minami, Y.5
Ohno, S.6
-
62
-
-
0026489693
-
Microtubule associated protein 2 level in hippocampus following traumatic brain injury
-
Taft W. C., Yang K., Dixon C. E., and Hayes R. L. (1992) Microtubule associated protein 2 level in hippocampus following traumatic brain injury. J. Neurotrauma 9, 281-290.
-
(1992)
J. Neurotrauma
, vol.9
, pp. 281-290
-
-
Taft, W.C.1
Yang, K.2
Dixon, C.E.3
Hayes, R.L.4
-
63
-
-
0027199244
-
Hypothermia attenuates the loss of hippocampal microtubule-associated protein 2 (MAP2) following traumatic brain injury
-
Taft W. C., Yang K., Dixon C. E., Clifton G. L., and Hayes R. L. (1993) Hypothermia attenuates the loss of hippocampal microtubule-associated protein 2 (MAP2) following traumatic brain injury. J. Cereb. Blood Flow Metab. 13, 796-802.
-
(1993)
J. Cereb. Blood Flow Metab.
, vol.13
, pp. 796-802
-
-
Taft, W.C.1
Yang, K.2
Dixon, C.E.3
Clifton, G.L.4
Hayes, R.L.5
-
64
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin H., Staehelin T., and Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
65
-
-
0027988820
-
Calpain inhibition: An overview of its therapeutic potential
-
Wang K. K. W. and Yuen P. W. (1994) Calpain inhibition: an overview of its therapeutic potential. Trends Pharmacol. Sci. 15, 412-419.
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 412-419
-
-
Wang, K.K.W.1
Yuen, P.W.2
-
66
-
-
0026715839
-
Alteration in the immunoreactivity of the calcineurin subunits after ischemia hippocampal damage
-
Yamasaki Y., Onodera H., Adachi K., Shozuhura H., and Kogure K. (1992) Alteration in the immunoreactivity of the calcineurin subunits after ischemia hippocampal damage. Neuroscience 49, 545-556.
-
(1992)
Neuroscience
, vol.49
, pp. 545-556
-
-
Yamasaki, Y.1
Onodera, H.2
Adachi, K.3
Shozuhura, H.4
Kogure, K.5
-
67
-
-
0025911090
-
Two stage autolysis of the catalytic subunit initiates activation of μ calpain
-
Zimmerman U. J. P. and Schlaepfer W. W. (1991) Two stage autolysis of the catalytic subunit initiates activation of μ calpain. Biochim. Biophys. Acta 1078, 192-198.
-
(1991)
Biochim. Biophys. Acta
, vol.1078
, pp. 192-198
-
-
Zimmerman, U.J.P.1
Schlaepfer, W.W.2
|