-
1
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki T., Sasaki Y., and Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305 (2004) 1010-1013
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
2
-
-
0025717816
-
The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease
-
Arnold S.E., Hyman B.T., Flory J., Damasio A.R., and Van Hoesen G.W. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb. Cortex 1 (1991) 103-116
-
(1991)
Cereb. Cortex
, vol.1
, pp. 103-116
-
-
Arnold, S.E.1
Hyman, B.T.2
Flory, J.3
Damasio, A.R.4
Van Hoesen, G.W.5
-
3
-
-
61449233205
-
Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration
-
Avery M.A., Sheehan A.E., Kerr K.S., Wang J., and Freeman M.R. Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration. J. Cell. Biol. 184 (2009) 501-513
-
(2009)
J. Cell. Biol.
, vol.184
, pp. 501-513
-
-
Avery, M.A.1
Sheehan, A.E.2
Kerr, K.S.3
Wang, J.4
Freeman, M.R.5
-
4
-
-
0029012892
-
Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability
-
Balducci E., Emanuelli M., Raffaelli N., Ruggieri S., Amici A., Magni G., Orsomando G., Polzonetti V., and Natalini P. Assay methods for nicotinamide mononucleotide adenylyltransferase of wide applicability. Anal. Biochem. 228 (1995) 64-68
-
(1995)
Anal. Biochem.
, vol.228
, pp. 64-68
-
-
Balducci, E.1
Emanuelli, M.2
Raffaelli, N.3
Ruggieri, S.4
Amici, A.5
Magni, G.6
Orsomando, G.7
Polzonetti, V.8
Natalini, P.9
-
5
-
-
4243098426
-
Neuroscience. NAD to the rescue
-
Bedalov A., and Simon J.A. Neuroscience. NAD to the rescue. Science 305 (2004) 954-955
-
(2004)
Science
, vol.305
, pp. 954-955
-
-
Bedalov, A.1
Simon, J.A.2
-
6
-
-
58849126602
-
Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo
-
Beirowski B., Babetto E., Gilley J., Mazzola F., Conforti L., Janeckova L., Magni G., Ribchester R.R., and Coleman M.P. Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo. J. Neurosci. 29 (2009) 653-668
-
(2009)
J. Neurosci.
, vol.29
, pp. 653-668
-
-
Beirowski, B.1
Babetto, E.2
Gilley, J.3
Mazzola, F.4
Conforti, L.5
Janeckova, L.6
Magni, G.7
Ribchester, R.R.8
Coleman, M.P.9
-
7
-
-
27744501798
-
Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms
-
Berger F., Lau C., Dahlmann M., and Ziegler M. Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. J. Biol. Chem. 280 (2005) 36334-36341
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36334-36341
-
-
Berger, F.1
Lau, C.2
Dahlmann, M.3
Ziegler, M.4
-
8
-
-
27644591304
-
Axon degeneration mechanisms: commonality amid diversity
-
Coleman M. Axon degeneration mechanisms: commonality amid diversity. Nat. Rev. Neurosci. 6 (2005) 889-898
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 889-898
-
-
Coleman, M.1
-
9
-
-
0036774951
-
Axon pathology in neurological disease: a neglected therapeutic target
-
Coleman M.P., and Perry V.H. Axon pathology in neurological disease: a neglected therapeutic target. Trends Neurosci. 25 (2002) 532-537
-
(2002)
Trends Neurosci.
, vol.25
, pp. 532-537
-
-
Coleman, M.P.1
Perry, V.H.2
-
10
-
-
0034633627
-
A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse
-
Conforti L., Tarlton A., Mack T.G., Mi W., Buckmaster E.A., Wagner D., Perry V.H., and Coleman M.P. A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 11377-11382
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 11377-11382
-
-
Conforti, L.1
Tarlton, A.2
Mack, T.G.3
Mi, W.4
Buckmaster, E.A.5
Wagner, D.6
Perry, V.H.7
Coleman, M.P.8
-
11
-
-
61449113031
-
Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice
-
Conforti L., Wilbrey A., Morreale G., Janeckova L., Beirowski B., Adalbert R., Mazzola F., Di Stefano M., Hartley R., Babetto E., Smith T., Gilley J., Billington R.A., Genazzani A.A., Ribchester R.R., Magni G., and Coleman M. Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice. J. Cell. Biol. 184 (2009) 491-500
-
(2009)
J. Cell. Biol.
, vol.184
, pp. 491-500
-
-
Conforti, L.1
Wilbrey, A.2
Morreale, G.3
Janeckova, L.4
Beirowski, B.5
Adalbert, R.6
Mazzola, F.7
Di Stefano, M.8
Hartley, R.9
Babetto, E.10
Smith, T.11
Gilley, J.12
Billington, R.A.13
Genazzani, A.A.14
Ribchester, R.R.15
Magni, G.16
Coleman, M.17
-
12
-
-
0035808313
-
Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase
-
Emanuelli M., Carnevali F., Saccucci F., Pierella F., Amici A., Raffaelli N., and Magni G. Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase. J. Biol. Chem. 276 (2001) 406-412
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 406-412
-
-
Emanuelli, M.1
Carnevali, F.2
Saccucci, F.3
Pierella, F.4
Amici, A.5
Raffaelli, N.6
Magni, G.7
-
13
-
-
63049111216
-
PCAF acetylates {beta}-catenin and improves its stability
-
Ge X., Jin Q., Zhang F., Yan T., and Zhai Q. PCAF acetylates {beta}-catenin and improves its stability. Mol. Biol. Cell. 20 (2009) 419-427
-
(2009)
Mol. Biol. Cell.
, vol.20
, pp. 419-427
-
-
Ge, X.1
Jin, Q.2
Zhang, F.3
Yan, T.4
Zhai, Q.5
-
14
-
-
2442528438
-
Wallerian degeneration as a window to peripheral neuropathy
-
Glass J.D. Wallerian degeneration as a window to peripheral neuropathy. J. Neurol. Sci. 220 (2004) 123-124
-
(2004)
J. Neurol. Sci.
, vol.220
, pp. 123-124
-
-
Glass, J.D.1
-
15
-
-
0021145680
-
Alzheimer's disease: cell-specific pathology isolates the hippocampal formation
-
Hyman B.T., Van Hoesen G.W., Damasio A.R., and Barnes C.L. Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science 225 (1984) 1168-1170
-
(1984)
Science
, vol.225
, pp. 1168-1170
-
-
Hyman, B.T.1
Van Hoesen, G.W.2
Damasio, A.R.3
Barnes, C.L.4
-
16
-
-
33846406104
-
Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axon-protective function
-
Jia H., Yan T., Feng Y., Zeng C., Shi X., and Zhai Q. Identification of a critical site in Wld(s): essential for Nmnat enzyme activity and axon-protective function. Neurosci. Lett. 413 (2007) 46-51
-
(2007)
Neurosci. Lett.
, vol.413
, pp. 46-51
-
-
Jia, H.1
Yan, T.2
Feng, Y.3
Zeng, C.4
Shi, X.5
Zhai, Q.6
-
17
-
-
63849199824
-
The NMN/NaMN adenylyltransferase (NMNAT) protein family
-
Lau C., Niere M., and Ziegler M. The NMN/NaMN adenylyltransferase (NMNAT) protein family. Front Biosci. 14 (2009) 410-431
-
(2009)
Front Biosci.
, vol.14
, pp. 410-431
-
-
Lau, C.1
Niere, M.2
Ziegler, M.3
-
18
-
-
65249173918
-
Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons
-
Liu D., Gharavi R., Pitta M., Gleichmann M., and Mattson M.P. Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons. Neuromolecular Med. 11 (2009) 28-42
-
(2009)
Neuromolecular Med.
, vol.11
, pp. 28-42
-
-
Liu, D.1
Gharavi, R.2
Pitta, M.3
Gleichmann, M.4
Mattson, M.P.5
-
19
-
-
33744926927
-
The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons
-
MacDonald J.M., Beach M.G., Porpiglia E., Sheehan A.E., Watts R.J., and Freeman M.R. The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron 50 (2006) 869-881
-
(2006)
Neuron
, vol.50
, pp. 869-881
-
-
MacDonald, J.M.1
Beach, M.G.2
Porpiglia, E.3
Sheehan, A.E.4
Watts, R.J.5
Freeman, M.R.6
-
20
-
-
0035195636
-
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene
-
Mack T.G., Reiner M., Beirowski B., Mi W., Emanuelli M., Wagner D., Thomson D., Gillingwater T., Court F., Conforti L., Fernando F.S., Tarlton A., Andressen C., Addicks K., Magni G., Ribchester R.R., Perry V.H., and Coleman M.P. Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat. Neurosci. 4 (2001) 1199-1206
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 1199-1206
-
-
Mack, T.G.1
Reiner, M.2
Beirowski, B.3
Mi, W.4
Emanuelli, M.5
Wagner, D.6
Thomson, D.7
Gillingwater, T.8
Court, F.9
Conforti, L.10
Fernando, F.S.11
Tarlton, A.12
Andressen, C.13
Addicks, K.14
Magni, G.15
Ribchester, R.R.16
Perry, V.H.17
Coleman, M.P.18
-
22
-
-
44949233176
-
Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress
-
Press C., and Milbrandt J. Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. J. Neurosci. 28 (2008) 4861-4871
-
(2008)
J. Neurosci.
, vol.28
, pp. 4861-4871
-
-
Press, C.1
Milbrandt, J.2
-
23
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff M.C., Whitmore A.V., and Finn J.T. Axonal self-destruction and neurodegeneration. Science 296 (2002) 868-871
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
24
-
-
0036031865
-
Identification of a novel human nicotinamide mononucleotide adenylyltransferase
-
Raffaelli N., Sorci L., Amici A., Emanuelli M., Mazzola F., and Magni G. Identification of a novel human nicotinamide mononucleotide adenylyltransferase. Biochem. Biophys. Res. Commun. 297 (2002) 835-840
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 835-840
-
-
Raffaelli, N.1
Sorci, L.2
Amici, A.3
Emanuelli, M.4
Mazzola, F.5
Magni, G.6
-
25
-
-
33748174151
-
Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
-
Sasaki Y., Araki T., and Milbrandt J. Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. J. Neurosci. 26 (2006) 8484-8491
-
(2006)
J. Neurosci.
, vol.26
, pp. 8484-8491
-
-
Sasaki, Y.1
Araki, T.2
Milbrandt, J.3
-
26
-
-
65649126738
-
Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide
-
Sasaki Y., Vohra B.P., Lund F.E., and Milbrandt J. Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. J. Neurosci. 29 (2009) 5525-5535
-
(2009)
J. Neurosci.
, vol.29
, pp. 5525-5535
-
-
Sasaki, Y.1
Vohra, B.P.2
Lund, F.E.3
Milbrandt, J.4
-
27
-
-
67049160318
-
NAD and axon degeneration: from the Wlds gene to neurochemistry
-
Wang J., and He Z. NAD and axon degeneration: from the Wlds gene to neurochemistry. Cell Adh. Migr. 3 (2009) 77-87
-
(2009)
Cell Adh. Migr.
, vol.3
, pp. 77-87
-
-
Wang, J.1
He, Z.2
-
28
-
-
23744474976
-
A local mechanism mediates NAD-dependent protection of axon degeneration
-
Wang J., Zhai Q., Chen Y., Lin E., Gu W., McBurney M.W., and He Z. A local mechanism mediates NAD-dependent protection of axon degeneration. J. Cell. Biol. 170 (2005) 349-355
-
(2005)
J. Cell. Biol.
, vol.170
, pp. 349-355
-
-
Wang, J.1
Zhai, Q.2
Chen, Y.3
Lin, E.4
Gu, W.5
McBurney, M.W.6
He, Z.7
-
29
-
-
0142071135
-
A method for the absolute quantification of cDNA using real-time PCR
-
Whelan J.A., Russell N.B., and Whelan M.A. A method for the absolute quantification of cDNA using real-time PCR. J. Immunol. Methods 278 (2003) 261-269
-
(2003)
J. Immunol. Methods
, vol.278
, pp. 261-269
-
-
Whelan, J.A.1
Russell, N.B.2
Whelan, M.A.3
-
30
-
-
66049102890
-
Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration
-
Yahata N., Yuasa S., and Araki T. Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration. J. Neurosci. 29 (2009) 6276-6284
-
(2009)
J. Neurosci.
, vol.29
, pp. 6276-6284
-
-
Yahata, N.1
Yuasa, S.2
Araki, T.3
-
31
-
-
0942279500
-
Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas
-
Yalowitz J.A., Xiao S., Biju M.P., Antony A.C., Cummings O.W., Deeg M.A., and Jayaram H.N. Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas. Biochem. J. 377 (2004) 317-326
-
(2004)
Biochem. J.
, vol.377
, pp. 317-326
-
-
Yalowitz, J.A.1
Xiao, S.2
Biju, M.P.3
Antony, A.C.4
Cummings, O.W.5
Deeg, M.A.6
Jayaram, H.N.7
-
32
-
-
34247195332
-
NAD+ and NADH in brain functions, brain diseases and brain aging
-
Ying W. NAD+ and NADH in brain functions, brain diseases and brain aging. Front Biosci. 12 (2007) 1863-1888
-
(2007)
Front Biosci.
, vol.12
, pp. 1863-1888
-
-
Ying, W.1
-
33
-
-
34547659994
-
NAD+ and NADH in neuronal death
-
Ying W. NAD+ and NADH in neuronal death. J. Neuroimmune Pharmacol. 2 (2007) 270-275
-
(2007)
J. Neuroimmune Pharmacol.
, vol.2
, pp. 270-275
-
-
Ying, W.1
-
34
-
-
0042848910
-
Involvement of the ubiquitin-proteasome system in the early stages of Wallerian degeneration
-
Zhai Q., Wang J., Kim A., Liu Q., Watts R., Hoopfer E., Mitchison T., Luo L., and He Z. Involvement of the ubiquitin-proteasome system in the early stages of Wallerian degeneration. Neuron 39 (2003) 217-225
-
(2003)
Neuron
, vol.39
, pp. 217-225
-
-
Zhai, Q.1
Wang, J.2
Kim, A.3
Liu, Q.4
Watts, R.5
Hoopfer, E.6
Mitchison, T.7
Luo, L.8
He, Z.9
-
35
-
-
33845477523
-
Drosophila NMNAT maintains neural integrity independent of Its NAD synthesis activity
-
Zhai R.G., Cao Y., Hiesinger P.R., Zhou Y., Mehta S.Q., Schulze K.L., Verstreken P., and Bellen H.J. Drosophila NMNAT maintains neural integrity independent of Its NAD synthesis activity. PLoS Biol. 4 (2006) e416
-
(2006)
PLoS Biol.
, vol.4
-
-
Zhai, R.G.1
Cao, Y.2
Hiesinger, P.R.3
Zhou, Y.4
Mehta, S.Q.5
Schulze, K.L.6
Verstreken, P.7
Bellen, H.J.8
-
36
-
-
42249103603
-
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
-
Zhai R.G., Zhang F., Hiesinger P.R., Cao Y., Haueter C.M., and Bellen H.J. NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature 452 (2008) 887-891
-
(2008)
Nature
, vol.452
, pp. 887-891
-
-
Zhai, R.G.1
Zhang, F.2
Hiesinger, P.R.3
Cao, Y.4
Haueter, C.M.5
Bellen, H.J.6
|