Fluctuation of synapse density in the arcuate nucleus during the estrous cycle

Neuroscience

Volumn 144, Issue 4, 2007, Pages 1288-1292

  Csakvari, E ^a   Hoyk, Z ^a   Gyenes, A ^a   Garcia Ovejero, D ^b   Garcia Segura, L M ^c   Parducz A ^a  

^a INSTITUTE OF BIOCHEMISTRY   (Hungary)

^b CSIC   (Spain)

^c INSTITUTO CAJAL   (Spain)

Author keywords

electron microscopic stereology; GABAergic; hormone; synaptic plasticity

Indexed keywords

4 AMINOBUTYRIC ACID; SEX HORMONE;

ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CELL COUNT; DENDRITIC SPINE; ENERGY BALANCE; ESTRUS CYCLE; FEMALE; GABAERGIC SYSTEM; HORMONE ACTION; HORMONE BLOOD LEVEL; HYPOTHALAMUS; IMMUNOCYTOCHEMISTRY; NERVE CELL; NEUROANATOMY; NEUROENDOCRINE SYSTEM; NONHUMAN; PHYSIOLOGY; PRIORITY JOURNAL; RAT; REPRODUCTION; STEREOMETRY; SYNAPSE;

ANIMALS; ARCUATE NUCLEUS; DENDRITIC SPINES; ESTROUS CYCLE; FEMALE; GAMMA-AMINOBUTYRIC ACID; GONADAL STEROID HORMONES; METESTRUS; MICROSCOPY, IMMUNOELECTRON; NEURONAL PLASTICITY; PRESYNAPTIC TERMINALS; PROESTRUS; RATS; RATS, WISTAR; SYNAPSES;

EID: 33846329102     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.11.008     Document Type: Article

References (32)

1. Amateau S.K., and McCarthy M.M. A novel mechanism of dendritic spine plasticity involving estradiol induction of prostaglandin-E2. J Neurosci 22 (2002) 8586-8596
2. Arnold A.P., and Breedlove S.M. Organizational and activational effects of sex steroids on brain and behavior: a reanalysis. Horm Behav 19 (1985) 469-498
3. Chronwall B.M. Anatomy and physiology of the neuroendocrine arcuate nucleus. Peptides 6 Suppl 2 (1985) 1-11
4. Frankfurt M., Gould E., Woolley C.S., and McEwen B.S. Gonadal steroids modify dendritic spine density in ventromedial hypothalamic neurons: a Golgi study in the adult rat. Neuroendocrinology 51 (1990) 530-535
5. Garcia-Segura L.M., Chowen J.A., Parducz A., and Naftolin F. Gonadal hormones as promoters of structural synaptic plasticity: cellular mechanisms. Prog Neurobiol 44 (1994) 279-307
6. Garcia-Segura L.M., Luquin S., Parducz A., and Naftolin F. Gonadal hormone regulation of glial fibrillary acidic protein immunoreactivity and glial ultrastructure in the rat neuroendocrine hypothalamus. Glia 10 (1994) 59-69
7. Gould E., Woolley C.S., Frankfurt M., and McEwen B.S. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J Neurosci 10 (1990) 1286-1291
8. Greenough W.T., Carter C.S., Steerman C., and DeVoogd T.J. Sex differences in dendritic patterns in hamster preoptic area. Brain Res 126 (1977) 63-72
9. Guillamon A., Segovia S., and del Abril A. Early effects of gonadal steroids on the neuron number in the medial posterior region and the lateral division of the bed nucleus of the stria terminalis in the rat. Brain Res Dev Brain Res 44 (1988) 281-290
10. Hoyk Z., Parducz A., and Theodosis D.T. The highly sialylated isoform of the neural cell adhesion molecule is required for estradiol-induced morphological synaptic plasticity in the adult arcuate nucleus. Eur J Neurosci 13 (2001) 649-656
11. Kretz O., Fester L., Wehrenberg U., Zhou L., Brauckmann S., Zhao S., Prange-Kiel J., Naumann T., Jarry H., Frotscher M., and Rune G.M. Hippocampal synapses depend on hippocampal estrogen synthesis. J Neurosci 24 (2004) 5913-5921
12. Leal S., Andrade J.P., Paula-Barbosa M.M., and Madeira M.D. Arcuate nucleus of the hypothalamus: effects of age and sex. J Comp Neurol 401 (1998) 65-88
13. Maclusky N.J., Luine V.N., Hajszan T., and Leranth C. The 17alpha and 17beta isomers of estradiol both induce rapid spine synapse formation in the CA1 hippocampal subfield of ovariectomized female rats. Endocrinology 146 (2005) 287-293
14. Matsumoto A., and Arai Y. Sexual dimorphism in "wiring pattern" in the hypothalamic arcuate nucleus and its modification by neonatal hormonal environment. Brain Res 190 (1980) 238-242
15. Mong J.A., Nunez J.L., and McCarthy M.M. GABA mediates steroid-induced astrocyte differentiation in the neonatal rat hypothalamus. J Neuroendocrinol 14 (2002) 45-55
16. Mong J.A., Roberts R.C., Kelly J.J., and McCarthy M.M. Gonadal steroids reduce the density of axospinous synapses in the developing rat arcuate nucleus: an electron microscopy analysis. J Comp Neurol 432 (2001) 259-267
17. Murphy D.D., Cole N.B., Greenberger V., and Segal M. Estradiol increases dendritic spine density by reducing GABA neurotransmission in hippocampal neurons. J Neurosci 18 (1998) 2550-2559
18. Naftolin F., Brown-Grant K., and Corker C.S. Plasma and pituitary luteinizing hormone and peripheral plasma oestradiol concentrations in the normal oestrous cycle of the rat and after experimental manipulation of the cycle. J Endocrinol 53 (1972) 17-30
19. Olmos G., Naftolin F., Perez J., Tranque P.A., and Garcia-Segura L.M. Synaptic remodeling in the rat arcuate nucleus during the estrous cycle. Neuroscience 32 (1989) 663-667
20. Parducz A., and Garcia-Segura L.M. Sexual differences in the synaptic connectivity in the rat dentate gyrus. Neurosci Lett 161 (1993) 53-56
21. Parducz A., Hoyk Z., Kis Z., and Garcia-Segura L.M. Hormonal enhancement of neuronal firing is linked to structural remodelling of excitatory and inhibitory synapses. Eur J Neurosci 16 (2002) 665-670
22. Parducz A., Perez J., and Garcia-Segura L.M. Estradiol induces plasticity of gabaergic synapses in the hypothalamus. Neuroscience 53 (1993) 395-401
23. Parducz A., Zsarnovszky A., Naftolin F., and Horvath T.L. Estradiol affects axo-somatic contacts of neuroendocrine cells in the arcuate nucleus of adult rats. Neuroscience 117 (2003) 791-794
24. Perez J., Luquin S., Naftolin F., and Garcia-Segura L.M. The role of estradiol and progesterone in phased synaptic remodelling of the rat arcuate nucleus. Brain Res 608 (1993) 38-44
25. Perez J., Naftolin F., and Garcia Segura L.M. Sexual differentiation of synaptic connectivity and neuronal plasma membrane in the arcuate nucleus of the rat hypothalamus. Brain Res 527 (1990) 116-122
26. Segal M., and Murphy D. Estradiol induces formation of dendritic spines in hippocampal neurons: functional correlates. Horm Behav 40 (2001) 156-159
27. Small S.V. Measurement of section thickness. In: Bocciarelli D.S. (Ed). Proc. 4th European congress on electron microscopy (1968), Poliglotta Vaticana, Rome 609-610
28. Somogyi P., and Hodgson A.J. Antisera to gamma-aminobutyric acid. III. Demonstration of GABA in Golgi-impregnated neurons and in conventional electron microscopic sections of cat striate cortex. J Histochem Cytochem 33 (1985) 249-257
29. Sterio D.C. The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134 Pt 2 (1984) 127-136
30. Uylings H.B., van Eden C.G., and Hofman M.A. Morphometry of size/volume variables and comparison of their bivariate relations in the nervous system under different conditions. J Neurosci Methods 18 (1986) 19-37
31. Woolley C.S., Gould E., Frankfurt M., and McEwen B.S. Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J Neurosci 10 (1990) 4035-4039
32. Woolley C.S., and McEwen B.S. Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J Neurosci 12 (1992) 2549-2554