Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 12, 2004, Pages 4112-4117

  Hansen, Jacob B ^a,b   Jørgensen, Claus ^a   Petersen, Rasmus K ^a   Hallenborg, Philip ^a   De Matteis, Rita ^c   Bøye, Hans A ^a   Petrovic, Natasa ^d   Enerbäck, Sven ^e   Nedergaard, Jan ^d   Cinti, Saverio ^c   Te Riele, Hein ^b   Kristiansen, Karsten ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^d STOCKHOLM UNIVERSITY   (Sweden)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORKHEAD TRANSCRIPTION FACTOR FOXC2; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; VIRUS ANTIGEN;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BROWN ADIPOSE TISSUE; CELL CYCLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL POPULATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FIBROBLAST; GENE EXPRESSION; GENE TARGETING; IMMUNOHISTOCHEMISTRY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIMIAN VIRUS 40; STEM CELL; UPREGULATION; WHITE ADIPOSE TISSUE; WILD TYPE;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CARRIER PROTEINS; CELL DIFFERENTIATION; CYCLIC AMP; FIBROBLASTS; ION CHANNELS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RETINOBLASTOMA PROTEIN; SIMIAN VIRUS 40;

ANIMALIA; SIMIAE; SIMIAN VIRUS 40;

EID: 12144287013     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0301964101     Document Type: Article

References (36)

1. Lowell, B. B. & Spiegelman, B. M. (2000) Nature 404, 652-660.
2. Rosen, E. D., Walkey, C. J., Puigserver, P. & Spiegelman, B. M. (2000) Genes Dev. 14, 1293-1307.
3. Lowell, B. B., S-Susulic, V., Hamann, A., Lawitts, J. A., Himms-Hagen, J., Boyer, B. B., Kozak, L. P. & Flier, J. S. (1993) Nature 366, 740-742.
4. Picard, F., Géhin, M., Annicotte, J.-S., Rocchi, S., Champy, M.-F., O'Malley, B. W., Chambon, P. & Auwerx, J. (2002) Cell 111, 931-941.
5. Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M. & Spiegelman, B. M. (1998) Cell 92, 829-839.
6. Cederberg, A., Grønning, L. M., Ahrén, B., Taskén, K., Carlsson, P. & Enerbäck, S. (2001) Cell 106, 563-573.
7. Harbour, J. W. & Dean, D. C. (2000) Genes Dev. 14, 2393-2409.
8. Lipinski, M. M. & Jacks, T. (2000) Oncogene 18, 7873-7882.
9. Chen, P.-L., Riley, D. J., Chen, Y. & Lee, W.-H. (1996) Genes Dev. 10, 2794-2804.
10. Hansen, J. B., Petersen, R. K., Larsen, B. M., Bartkova, J., Alsner, J. & Kristiansen, K. (1999) J. Biol. Chem. 274, 2386-2393.
11. Hansen, J. B., Petersen, R. K., Jørgensen, C. & Kristiansen, K. (2002) J. Biol. Chem. 277, 26335-26339.
12. Himms-Hagen, J., Melnyk, A., Zingaretti, M. C., Ceresi, E., Barbatelli, G. & Cinti, S. (2000) Am. J. Physiol. 279, C670-C681.
13. Hansen, J. B., Zhang, H., Rasmussen, T. H., Petersen, R. K., Flindt, E. N. & Kristiansen, K. (2001) J. Biol. Chem. 276, 3175-3182.
14. Dannenberg, J.-H., van Rossum, A., Schuijff, L. & te Riele, H. (2000) Genes Dev. 14, 3051-3064.
15. Rosen, E. D., Sarraf, P., Troy, A. E., Bradwin, G., Moore, K., Milstone, D. S., Spiegelman, B. M. & Mortensen, R. M. (1999) Mol. Cell 4, 611-617.
16. Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B. B., Scarpulla, R. C. & Spiegelman, B. M. (1999) Cell 98, 115-124.
17. Benito, M., Porras, A. & Santos, E. (1993) Exp. Cell Res. 209, 248-254.
18. Kozak, U. C., Held, W., Kreutter, D. & Kozak, L. P. (1992) Mol. Endocrinol. 6, 763-772.
19. Rohlfs, E. M., Daniels, K. W., Premont, R. T., Kozak, L. P. & Collins, S. (1995) J. Biol. Chem. 270, 10723-10732.
20. Ross, S. R., Choy, L., Graves, R. A., Fox, N., Solevjeva, V., Klaus, S., Ricquier, D. & Spiegelman, B. M. (1992) Proc. Natl. Acad. Sci. USA 89, 7561-7565.
21. Cherington, V., Morgan, B., Spiegelman, B. M. & Roberts, T. M. (1986) Proc. Natl. Acad. Sci. USA 83, 4307-4311.
22. Higgins, C., Chatterjee, S. & Cherington, V. (1996) J. Virol. 70, 745-752.
23. Ali, S. H. & DeCaprio, J. A. (2001) Semin. Cancer Biol. 11, 15-23.
24. Puigserver, P., Vazquez, F., Bonet, M. L., Pico, C. & Palou, A. (1996) Biochem. J. 317, 827-833.
25. Issemann, I. & Green, S. (1990) Nature 347, 645-650.
26. Lin, J., Puigserver, P., Donovan, J., Tarr, P. & Spiegelman, B. M. (2002) J. Biol. Chem. 277, 1645-1648.
27. Masuda, N., Yasumo, H., Furusawa, T., Tsukamoto, T., Sadano, H. & Osumi, T. (1998) Gene 221, 225-233.
28. Ricquier, D. & Bouillaud, F. (2000) J. Physiol. 529, 3-10.
29. Larsson, N.-G., Wang, J., Wilhelmsson, H., Oldfors, A., Rustin, P., Lewandoski, M., Barsh, G. S. & Clayton, D. A. (1998) Nat. Genet. 18, 231-236.
30. Scarpulla, R. C. (2002) Biochim. Biophys. Acta 1576, 1-14.
31. Cinti, S. (2002) J. Endocrinol. Invest. 25, 823-835.
32. Houstek, J., Kopecky, J., Rychter, Z. & Soukup, T. (1988) Biochim. Biophys. Acta 935, 19-25.
33. Moulin, K., Truel, N., André, M., Arnauld, E., Nibbelink, M., Cousin, B., Dani, C., Pénicaud, L. & Casteilla, L. (2001) Biochem. J. 356, 659-664.
34. Rehnmark, S. & Nedergaard, J. (1989) Exp. Cell Res. 180, 574-579.
35. Herzig, S., Long, F., Jhala, U. S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, R., Schutz, G., Yoon, C., Puigserver, P., Spiegelman, B. & Montminy, M. (2001) Nature 413, 179-183.
36. Chang, K.-H., Chen, Y., Chen, T.-T., Chou, W.-H., Chen, P.-L., Ma, Y.-Y., Yang-Feng, T. L., Leng, X., Tsai, M.-J., O'Malley, B. W. et al.. (1997) Proc. Natl. Acad. Sci. USA 94, 9040-9045.