-
1
-
-
33847768085
-
Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
-
Almind, K., M. Manieri, W. I. Sivitz, S. Cinti, and C. R. Kahn. 2007. Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice. Proc. Natl. Acad. Sci. USA 104:2366-2371.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 2366-2371
-
-
Almind, K.1
Manieri, M.2
Sivitz, W.I.3
Cinti, S.4
Kahn, C.R.5
-
2
-
-
0035847001
-
Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell
-
Barbera, M. J., A. Schluter, N. Pedraza, R. Iglesias, F. Villarroya, and M. Giralt. 2001. Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell. J. Biol. Chem. 276:1486-1493.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 1486-1493
-
-
Barbera, M.J.1
Schluter, A.2
Pedraza, N.3
Iglesias, R.4
Villarroya, F.5
Giralt, M.6
-
3
-
-
0031735351
-
Leptin and UCP1 genes are reciprocally regulated in brown adipose tissue
-
Cancello, R., M. C. Zingaretti, R. Sarzani, D. Ricquier, and S. Cinti. 1998. Leptin and UCP1 genes are reciprocally regulated in brown adipose tissue. Endocrinology 139:4747-4750.
-
(1998)
Endocrinology
, vol.139
, pp. 4747-4750
-
-
Cancello, R.1
Zingaretti, M.C.2
Sarzani, R.3
Ricquier, D.4
Cinti, S.5
-
4
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon, B., and J. Nedergaard. 2004. Brown adipose tissue: function and physiological significance. Physiol. Rev. 84:277-359.
-
(2004)
Physiol. Rev
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
5
-
-
0035920122
-
β-Adrenergic activation of p38 MAP kinase in adipocytes: CAMP induction of the uncoupling protein-1 (UCP1) gene requires p38 MAP kinase
-
Cao, W., A. V. Medvedev, K. W. Daniel, and S. Collins. 2001. β-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein-1 (UCP1) gene requires p38 MAP kinase. J. Biol. Chem. 276:27077-27082.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 27077-27082
-
-
Cao, W.1
Medvedev, A.V.2
Daniel, K.W.3
Collins, S.4
-
6
-
-
1642293248
-
p38 MAP kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
-
Cao, W., J. Robidoux, P. Puigserver, K. W. Daniel, A. V. Medvedev, X. Bai, L. M. Fleering, B. M. Spiegelman, and S. Collins. 2004. p38 MAP kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Mol. Cell. Biol. 24:3057-3067.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 3057-3067
-
-
Cao, W.1
Robidoux, J.2
Puigserver, P.3
Daniel, K.W.4
Medvedev, A.V.5
Bai, X.6
Fleering, L.M.7
Spiegelman, B.M.8
Collins, S.9
-
7
-
-
0027300035
-
Tissue-specific and β-adrenergic regulation of the mitochondrial uncoupling protein gene: Control by cis-acting elements in the 5′-flanking region
-
Cassard-Doulcier, A.-M., C. Gelly, N. Fox, J. Schrementi, S. Raimbault, S. Klaus, C. Forest, F. Bouillard, and D. Ricquier. 1993. Tissue-specific and β-adrenergic regulation of the mitochondrial uncoupling protein gene: control by cis-acting elements in the 5′-flanking region. Mol. Endocrinol. 7:497-506.
-
(1993)
Mol. Endocrinol
, vol.7
, pp. 497-506
-
-
Cassard-Doulcier, A.-M.1
Gelly, C.2
Fox, N.3
Schrementi, J.4
Raimbault, S.5
Klaus, S.6
Forest, C.7
Bouillard, F.8
Ricquier, D.9
-
8
-
-
27144476457
-
RIP140-targeted repression of gene expression in adipocytes
-
Christian, M., E. Kiskinis, D. Debevec, G. Leonardsson, R. White, and M. G. Parker. 2005. RIP140-targeted repression of gene expression in adipocytes. Mol. Cell. Biol. 25:9383-9391.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 9383-9391
-
-
Christian, M.1
Kiskinis, E.2
Debevec, D.3
Leonardsson, G.4
White, R.5
Parker, M.G.6
-
9
-
-
0004236075
-
-
Editrice Kurtis, Milan, Italy
-
Cinti, S. 1999. The adipose organ. Editrice Kurtis, Milan, Italy.
-
(1999)
The adipose organ
-
-
Cinti, S.1
-
11
-
-
4544357340
-
Learning new tricks from old dogs: Beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism
-
Collins, S., W. Cao, and J. Robidoux. 2004. Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. Mol. Endocrinol. 18:2123-2131.
-
(2004)
Mol. Endocrinol
, vol.18
, pp. 2123-2131
-
-
Collins, S.1
Cao, W.2
Robidoux, J.3
-
12
-
-
0031025546
-
Strain-specific response to β3-adrenergic receptor agonist treatment of diet-induced obesity in mice
-
Collins, S., K. W. Daniel, A. E. Petro, and R. S. Surwit. 1997. Strain-specific response to β3-adrenergic receptor agonist treatment of diet-induced obesity in mice. Endocrinology 138:405-413.
-
(1997)
Endocrinology
, vol.138
, pp. 405-413
-
-
Collins, S.1
Daniel, K.W.2
Petro, A.E.3
Surwit, R.S.4
-
13
-
-
0348111308
-
Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor {alpha}
-
Dalen, K. T., S. M. Ulven, K. Bamberg, J.-A. Gustafsson, and H. I. Nebb. 2003. Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor {alpha}. J. Biol. Chem. 278: 48283-48291.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 48283-48291
-
-
Dalen, K.T.1
Ulven, S.M.2
Bamberg, K.3
Gustafsson, J.-A.4
Nebb, H.I.5
-
14
-
-
34347261400
-
Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen related receptor alpha
-
Debevec, D., M. Christian, D. Morganstein, A. Seth, M. Parker, and R. White. 2007. Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen related receptor alpha. Mol. Endocrinol. 21:1581-1592.
-
(2007)
Mol. Endocrinol
, vol.21
, pp. 1581-1592
-
-
Debevec, D.1
Christian, M.2
Morganstein, D.3
Seth, A.4
Parker, M.5
White, R.6
-
15
-
-
0034644662
-
Transcriptional activation of the human ucpl gene in a rodent cell line. Synergism of retinoids, isoproterenol, and thiazolidinediones is mediated by a multipartite response element
-
del Mar Gonzalez-Barroso, M., C. Pecqueur, C. Gelly, D. Sanchis, M. C. Alves-Guerra, F. Bouillaud, D. Ricquier, and A. M. Cassard-Doulcier. 2000. Transcriptional activation of the human ucpl gene in a rodent cell line. Synergism of retinoids, isoproterenol, and thiazolidinediones is mediated by a multipartite response element. J. Biol. Chem. 275:31722-31732.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 31722-31732
-
-
del Mar1
Gonzalez-Barroso, M.2
Pecqueur, C.3
Gelly, C.4
Sanchis, D.5
Alves-Guerra, M.C.6
Bouillaud, F.7
Ricquier, D.8
Cassard-Doulcier, A.M.9
-
16
-
-
0037250915
-
Regulation and co-ordination of nuclear gene expression during mitochondrial biogenesis
-
Goffart, S., and R. Wiesner. 2003. Regulation and co-ordination of nuclear gene expression during mitochondrial biogenesis. Exp. Physiol. 88:33-40.
-
(2003)
Exp. Physiol
, vol.88
, pp. 33-40
-
-
Goffart, S.1
Wiesner, R.2
-
17
-
-
0030039131
-
Activation of the uncoupling protein by fatty acids is modulated by mutations in the C-terminal region of the protein
-
Gonzalez-Barroso, M. M., C. Fleury, I. Arechaga, P. Zaragoza, C. Levi-Meyrueis, S. Raimbault, D. Ricquier, F. Bouillaud, and E. Rial. 1996. Activation of the uncoupling protein by fatty acids is modulated by mutations in the C-terminal region of the protein. Eur. J. Biochem. 239:445-450.
-
(1996)
Eur. J. Biochem
, vol.239
, pp. 445-450
-
-
Gonzalez-Barroso, M.M.1
Fleury, C.2
Arechaga, I.3
Zaragoza, P.4
Levi-Meyrueis, C.5
Raimbault, S.6
Ricquier, D.7
Bouillaud, F.8
Rial, E.9
-
18
-
-
0032528169
-
Emergence of brown adipocytes in white fat in mice is under genetic control: Effects on body weight and adiposity
-
Guerra, C., R. A. Koza, H. Yamashita, K. Walsh, and L. P. Kozak. 1998. Emergence of brown adipocytes in white fat in mice is under genetic control: effects on body weight and adiposity. J. Clin. Investig. 102:412-420.
-
(1998)
J. Clin. Investig
, vol.102
, pp. 412-420
-
-
Guerra, C.1
Koza, R.A.2
Yamashita, H.3
Walsh, K.4
Kozak, L.P.5
-
19
-
-
33845596500
-
PGC-1 coactivators, energy homeostasis, and metabolism
-
Handschin, C., and B. M. Spiegelman. 2006. PGC-1 coactivators, energy homeostasis, and metabolism. Endocr. Rev. 27:728-735.
-
(2006)
Endocr. Rev
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
20
-
-
33748366392
-
Regulatory circuits controlling white versus brown adipocyte differentiation
-
Hansen, J. B., and K. Kristiansen. 2006. Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem. J. 398:153-168.
-
(2006)
Biochem. J
, vol.398
, pp. 153-168
-
-
Hansen, J.B.1
Kristiansen, K.2
-
21
-
-
0029978613
-
Transactivation by the thyroid hormone receptor is dependent on the spacer sequence in hormone response elements containing directly repeated half-sites
-
Harbers, M., G. Wahlstrom, and B. Vennstrom. 1996. Transactivation by the thyroid hormone receptor is dependent on the spacer sequence in hormone response elements containing directly repeated half-sites. Nucleic Acids Res. 24:2252-2259.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2252-2259
-
-
Harbers, M.1
Wahlstrom, G.2
Vennstrom, B.3
-
22
-
-
0014031401
-
Distinction of brown from white adipose tissue
-
Hull, D., and M. M. Segall. 1966. Distinction of brown from white adipose tissue. Nature 212:469-472.
-
(1966)
Nature
, vol.212
, pp. 469-472
-
-
Hull, D.1
Segall, M.M.2
-
23
-
-
12444295462
-
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling
-
Ide, T., H. Shimano, T. Yoshikawa, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, M. Nakakuki, S. Yatoh, Y. Iizuka, S. Tomita, K. Ohashi, A. Takahashi, H. Sone, T. Gotoda, J. Osuga, S. Ishibashi, and N. Yamada. 2003. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. Mol. Endocrinol. 17:1255-1267.
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 1255-1267
-
-
Ide, T.1
Shimano, H.2
Yoshikawa, T.3
Yahagi, N.4
Amemiya-Kudo, M.5
Matsuzaka, T.6
Nakakuki, M.7
Yatoh, S.8
Iizuka, Y.9
Tomita, S.10
Ohashi, K.11
Takahashi, A.12
Sone, H.13
Gotoda, T.14
Osuga, J.15
Ishibashi, S.16
Yamada, N.17
-
24
-
-
0033524420
-
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
-
Janowski, B. A., M. J. Grogan, S. A. Jones, G. B. Wisely, S. A. Kliewer, E. J. Corey, and D. J. Mangelsdorf. 1999. Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. Proc. Natl. Acad. Sci. USA 96:266-271.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 266-271
-
-
Janowski, B.A.1
Grogan, M.J.2
Jones, S.A.3
Wisely, G.B.4
Kliewer, S.A.5
Corey, E.J.6
Mangelsdorf, D.J.7
-
25
-
-
0037312554
-
On the role of liver X receptors in lipid accumulation in adipocytes
-
Juvet, L. K., S. M. Andresen, G. U. Schuster, K. T. Dalen, K. A. R. Tobin, K. Heilung, F. Haugen, S. Jacinto, S. M. Ulven, K. Bamberg, J.-A. Gustafsson, and H. I. Nebb. 2003. On the role of liver X receptors in lipid accumulation in adipocytes. Mol. Endocrinol. 17:172-182.
-
(2003)
Mol. Endocrinol
, vol.17
, pp. 172-182
-
-
Juvet, L.K.1
Andresen, S.M.2
Schuster, G.U.3
Dalen, K.T.4
Tobin, K.A.R.5
Heilung, K.6
Haugen, F.7
Jacinto, S.8
Ulven, S.M.9
Bamberg, K.10
Gustafsson, J.-A.11
Nebb, H.I.12
-
26
-
-
24144490445
-
LXRs regulate the balance between fat storage and oxidation
-
Kalaany, N. Y., K. C. Gauthier, A. M. Zavacki, P. P. Mammen, T. Kitazume, J. A. Peterson, J. D. Horton, D. J. Garry, A. C. Bianco, and D. J. Mangelsdorf. 2005. LXRs regulate the balance between fat storage and oxidation. Cell Metab. 1:231-244.
-
(2005)
Cell Metab
, vol.1
, pp. 231-244
-
-
Kalaany, N.Y.1
Gauthier, K.C.2
Zavacki, A.M.3
Mammen, P.P.4
Kitazume, T.5
Peterson, J.A.6
Horton, J.D.7
Garry, D.J.8
Bianco, A.C.9
Mangelsdorf, D.J.10
-
27
-
-
0029894407
-
Reduction of dietary obesity in aP2-Ucp transgenic mice: Mechanism and adipose tissue morphology
-
Kopecky, J., M. Rossmeisl, Z. Hodny, I. Syrovy, M. Horakova, and P. Kolarova. 1996. Reduction of dietary obesity in aP2-Ucp transgenic mice: mechanism and adipose tissue morphology. Am. J. Physiol. 270:E776-E786.
-
(1996)
Am. J. Physiol
, vol.270
-
-
Kopecky, J.1
Rossmeisl, M.2
Hodny, Z.3
Syrovy, I.4
Horakova, M.5
Kolarova, P.6
-
28
-
-
0028153698
-
An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene
-
Kozak, U. C., J. Kopecky, J. Teisinger, S. Enerback, B. Boyer, and L. P. Kozak. 1994. An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene. Mol. Cell. Biol. 14:59-67.
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 59-67
-
-
Kozak, U.C.1
Kopecky, J.2
Teisinger, J.3
Enerback, S.4
Boyer, B.5
Kozak, L.P.6
-
29
-
-
0037965630
-
Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue
-
Laffitte, B. A., L. C. Chao, J. Li, R. Walczak, S. Hummasti, S. B. Joseph, A. Castrillo, D. C. Wilpitz, D. J. Mangelsdorf, J. L. Collins, E. Saez, and P. Tontonoz. 2003. Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proc. Natl. Acad. Sci. USA 100:5419-5424.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5419-5424
-
-
Laffitte, B.A.1
Chao, L.C.2
Li, J.3
Walczak, R.4
Hummasti, S.5
Joseph, S.B.6
Castrillo, A.7
Wilpitz, D.C.8
Mangelsdorf, D.J.9
Collins, J.L.10
Saez, E.11
Tontonoz, P.12
-
30
-
-
2942532305
-
Nuclear receptor corepressor RIP140 regulates fat accumulation
-
Leonardsson, G., J. H. Steel, M. Christian, V. Pocock, S. Milligan, J. Bell, P. W. So, G. Medina-Gomez, A. Vidal-Puig, R. White, and M. G. Parker. 2004. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc. Natl. Acad. Sci. USA 101:8437-8442.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8437-8442
-
-
Leonardsson, G.1
Steel, J.H.2
Christian, M.3
Pocock, V.4
Milligan, S.5
Bell, J.6
So, P.W.7
Medina-Gomez, G.8
Vidal-Puig, A.9
White, R.10
Parker, M.G.11
-
31
-
-
33845656956
-
Mitochondrial retrograde signaling
-
Liu, Z., and R. A. Butow. 2006. Mitochondrial retrograde signaling. Annu. Rev. Genet. 40:159-185.
-
(2006)
Annu. Rev. Genet
, vol.40
, pp. 159-185
-
-
Liu, Z.1
Butow, R.A.2
-
32
-
-
0242580188
-
Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha
-
Luo, J., R. Sladek, J. Carrier, J. A. Bader, D. Richard, and V. Giguere. 2003. Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol. Cell. Biol. 23:7947-7956.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 7947-7956
-
-
Luo, J.1
Sladek, R.2
Carrier, J.3
Bader, J.A.4
Richard, D.5
Giguere, V.6
-
33
-
-
0035815650
-
Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-gamma-dependent activation
-
Medvedev, A. V., S. K. Snedden, S. Raimbault, D. Ricquier, and S. Collins. 2001. Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-gamma-dependent activation. J. Biol. Chem. 276:10817-10823.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 10817-10823
-
-
Medvedev, A.V.1
Snedden, S.K.2
Raimbault, S.3
Ricquier, D.4
Collins, S.5
-
34
-
-
33845542745
-
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
-
Morino, K., K. F. Petersen, and G. I. Shulman. 2006. Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 55:S9-S15.
-
(2006)
Diabetes
, vol.55
-
-
Morino, K.1
Petersen, K.F.2
Shulman, G.I.3
-
35
-
-
10044251948
-
Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland
-
Morroni, M., A. Giordano, M. C. Zingaretti, R. Boiani, R. De Matteis, B. B. Kahn, E. Nisoli, C. Tonello, C. Pisoschi, M. M. Luchetti, M. Marelli, and S. Cinti. 2004. Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland. Proc. Natl. Acad. Sci. USA 101:16801-16806.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16801-16806
-
-
Morroni, M.1
Giordano, A.2
Zingaretti, M.C.3
Boiani, R.4
De Matteis, R.5
Kahn, B.B.6
Nisoli, E.7
Tonello, C.8
Pisoschi, C.9
Luchetti, M.M.10
Marelli, M.11
Cinti, S.12
-
36
-
-
0021089059
-
Development of brown fat cells in monolayer culture. I. Morphological and biochemical distinction from white fat cells in culture
-
Nechad, M., P. Kuusela, C. Carneheim, P. Bjorntorp, J. Nedergaard, and B. Cannon. 1983. Development of brown fat cells in monolayer culture. I. Morphological and biochemical distinction from white fat cells in culture. Exp. Cell Res. 149:105-118.
-
(1983)
Exp. Cell Res
, vol.149
, pp. 105-118
-
-
Nechad, M.1
Kuusela, P.2
Carneheim, C.3
Bjorntorp, P.4
Nedergaard, J.5
Cannon, B.6
-
37
-
-
0021067975
-
Development of brown fat cells in monolayer culture. II. Ultrastructural characterization of precursors, differentiating adipocytes and their mitochondria
-
Nechad, M., P. Kuusela, C. Carneheim, P. Bjorntorp, J. Nedergaard, and B. Cannon. 1983. Development of brown fat cells in monolayer culture. II. Ultrastructural characterization of precursors, differentiating adipocytes and their mitochondria. Exp. Cell Res. 149:119-127.
-
(1983)
Exp. Cell Res
, vol.149
, pp. 119-127
-
-
Nechad, M.1
Kuusela, P.2
Carneheim, C.3
Bjorntorp, P.4
Nedergaard, J.5
Cannon, B.6
-
39
-
-
33845948962
-
RIP140 expression is stimulated by estrogen-related receptor {alpha} during adipogenesis
-
Nichol, D., M. Christian, J. H. Steel, R. White, and M. G. Parker. 2006. RIP140 expression is stimulated by estrogen-related receptor {alpha} during adipogenesis. J. Biol. Chem. 281:32140-32147.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 32140-32147
-
-
Nichol, D.1
Christian, M.2
Steel, J.H.3
White, R.4
Parker, M.G.5
-
40
-
-
31044432605
-
Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes
-
Powelka, A. M., A. Seth, J. V. Virbasius, E. Kiskinis, S. M. Nicoloro, A. Guilherme, X. Tang, J. Straubhaar, A. D. Cherniack, M. G. Parker, and M. P. Czech. 2006. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J. Clin. Investig. 116:125-136.
-
(2006)
J. Clin. Investig
, vol.116
, pp. 125-136
-
-
Powelka, A.M.1
Seth, A.2
Virbasius, J.V.3
Kiskinis, E.4
Nicoloro, S.M.5
Guilherme, A.6
Tang, X.7
Straubhaar, J.8
Cherniack, A.D.9
Parker, M.G.10
Czech, M.P.11
-
41
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver, P., Z. Wu, C. Park, R. Graves, M. Wright, and B. Spiegelman. 1998. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92:829-839.
-
(1998)
Cell
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.3
Graves, R.4
Wright, M.5
Spiegelman, B.6
-
42
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
-
Repa, J. J., G. Liang, J. Ou, Y. Bashmakov, J. M. Lobaccaro, I. Shimomura, B. Shan, M. S. Brown, J. L. Goldstein, and D. J. Mangelsdorf. 2000. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev. 14:2819-2830.
-
(2000)
Genes Dev
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
43
-
-
0037072886
-
Regulatory motifs for CREB-binding protein and Nfe212 transcription factors in the upstream enhancer of the mitochondrial uncoupling protein 1 gene
-
Rim, J. S., and L. P. Kozak. 2002. Regulatory motifs for CREB-binding protein and Nfe212 transcription factors in the upstream enhancer of the mitochondrial uncoupling protein 1 gene. J. Biol. Chem. 277:34589-34600.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 34589-34600
-
-
Rim, J.S.1
Kozak, L.P.2
-
44
-
-
20744441357
-
Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38α MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes
-
Robidoux, J., W. Cao, H. Quan, K. W. Daniel, F. Moukdar, X. Bai, L. M. Fleering, and S. Collins. 2005. Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38α MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. Mol. Cell. Biol. 25:5466-5479.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 5466-5479
-
-
Robidoux, J.1
Cao, W.2
Quan, H.3
Daniel, K.W.4
Moukdar, F.5
Bai, X.6
Fleering, L.M.7
Collins, S.8
-
45
-
-
1342323625
-
Beta-adrenergic receptors and regulation of energy expenditure: A family affair
-
Robidoux, J., T. L. Martin, and S. Collins. 2004. Beta-adrenergic receptors and regulation of energy expenditure: a family affair. Annu. Rev. Pharmacol. Toxicol. 44:297-323.
-
(2004)
Annu. Rev. Pharmacol. Toxicol
, vol.44
, pp. 297-323
-
-
Robidoux, J.1
Martin, T.L.2
Collins, S.3
-
46
-
-
33845864967
-
Adipocytes as regulators of energy balance and glucose homeostasis
-
Rosen, E. D., and B. M. Spiegelman. 2006. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 444:847-853.
-
(2006)
Nature
, vol.444
, pp. 847-853
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
47
-
-
33744792310
-
Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
-
Rosenfeld, M. G., V. V. Lunyak, and C. K. Glass. 2006. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 20:1405-1428.
-
(2006)
Genes Dev
, vol.20
, pp. 1405-1428
-
-
Rosenfeld, M.G.1
Lunyak, V.V.2
Glass, C.K.3
-
48
-
-
0026655613
-
Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene
-
Ross, S. R., L. Choy, R. A. Graves, N. Fox, V. Solevjeva, S. Klaus, D. Ricquier, and B. M. Spiegelman. 1992. Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene. Proc. Natl. Acad. Sci. USA 89:7561-7565.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7561-7565
-
-
Ross, S.R.1
Choy, L.2
Graves, R.A.3
Fox, N.4
Solevjeva, V.5
Klaus, S.6
Ricquier, D.7
Spiegelman, B.M.8
-
49
-
-
18244386043
-
Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo
-
Rossmeisl, M., G. Barbatelli, P. Flachs, P. Brauner, M. C. Zingaretti, M. Marelli, P. Janovska, M. Horakova, I. Syrovy, S. Cinti, and J. Kopecky. 2002. Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo. Eur. J. Biochem. 269:19-28.
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 19-28
-
-
Rossmeisl, M.1
Barbatelli, G.2
Flachs, P.3
Brauner, P.4
Zingaretti, M.C.5
Marelli, M.6
Janovska, P.7
Horakova, M.8
Syrovy, I.9
Cinti, S.10
Kopecky, J.11
-
50
-
-
0018646453
-
A role for brown adipose tissue in diet-induced thermogenesis
-
Rothwell, N. J., and M. J. Stock. 1979. A role for brown adipose tissue in diet-induced thermogenesis. Nature 281:31-35.
-
(1979)
Nature
, vol.281
, pp. 31-35
-
-
Rothwell, N.J.1
Stock, M.J.2
-
51
-
-
34347326271
-
Transcriptional control of brown fat determination by PRDM16
-
Seale, P., S. Kajimura, W. Yang, S. Chin, L. Rohas, M. Uldry, G. Tavernier, D. Langin, and B. M. Spiegelman. 2007. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 6:38-54.
-
(2007)
Cell Metab
, vol.6
, pp. 38-54
-
-
Seale, P.1
Kajimura, S.2
Yang, W.3
Chin, S.4
Rohas, L.5
Uldry, M.6
Tavernier, G.7
Langin, D.8
Spiegelman, B.M.9
-
52
-
-
0029941669
-
Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: Regulation by peroxisome proliferator-activated receptor gamma
-
Sears, I. B., M. A. MacGinnitie, L. G. Kovacs, and R. A. Graves. 1996. Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gamma. Mol. Cell. Biol. 16:3410-3419.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 3410-3419
-
-
Sears, I.B.1
MacGinnitie, M.A.2
Kovacs, L.G.3
Graves, R.A.4
-
53
-
-
11144356074
-
Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression
-
Seo, J. B., H. M. Moon, W. S. Kim, Y. S. Lee, H. W. Jeong, E. J. Yoo, J. Ham, H. Kang, M. G. Park, K. R. Steffensen, T. M. Stulnig, J. A. Gustafsson, S. D. Park, and J. B. Kim. 2004. Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression. Mol. Cell. Biol. 24:3430-3444.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 3430-3444
-
-
Seo, J.B.1
Moon, H.M.2
Kim, W.S.3
Lee, Y.S.4
Jeong, H.W.5
Yoo, E.J.6
Ham, J.7
Kang, H.8
Park, M.G.9
Steffensen, K.R.10
Stulnig, T.M.11
Gustafsson, J.A.12
Park, S.D.13
Kim, J.B.14
-
54
-
-
4644295401
-
Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids
-
Shabalina, I. G., A. Jacobsson, B. Cannon, and J. Nedergaard. 2004. Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids. J. Biol. Chem. 279:38236-38248.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 38236-38248
-
-
Shabalina, I.G.1
Jacobsson, A.2
Cannon, B.3
Nedergaard, J.4
-
55
-
-
33645873573
-
Thermogenic mechanisms and their hormonal regulation
-
Silva, J. E. 2006. Thermogenic mechanisms and their hormonal regulation. Physiol. Rev. 86:435-464.
-
(2006)
Physiol. Rev
, vol.86
, pp. 435-464
-
-
Silva, J.E.1
-
56
-
-
0017367947
-
Protein kinases in brown adipose tissue of developing rats. State of activation of protein kinase during development and cold exposure and its relationship to adenosine 3′:5′-monophosphate, lipolysis, and heat production
-
Skala, J. P., and B. L. Knight. 1977. Protein kinases in brown adipose tissue of developing rats. State of activation of protein kinase during development and cold exposure and its relationship to adenosine 3′:5′-monophosphate, lipolysis, and heat production. J. Biol. Chem. 252:1064-4070.
-
(1977)
J. Biol. Chem
, vol.252
, pp. 1064-4070
-
-
Skala, J.P.1
Knight, B.L.2
-
57
-
-
0034770191
-
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1
-
Tsukiyama-Kohara, K., F. Poulin, M. Kohara, C. T. DeMaria, A. Cheng, Z. Wu, A.-C. Gingras, A. Katsume, M. Elchebly, B. M. Spiegelman, M.-E. Harper, M. L. Tremblay, and N. Sonenberg. 2001. Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Nat. Med. 7:1128-1132.
-
(2001)
Nat. Med
, vol.7
, pp. 1128-1132
-
-
Tsukiyama-Kohara, K.1
Poulin, F.2
Kohara, M.3
DeMaria, C.T.4
Cheng, A.5
Wu, Z.6
Gingras, A.-C.7
Katsume, A.8
Elchebly, M.9
Spiegelman, B.M.10
Harper, M.-E.11
Tremblay, M.L.12
Sonenberg, N.13
-
58
-
-
12144291468
-
Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: Putative role of LXRs in lipid detoxification processes
-
Volle, D. H., J. J. Repa, A. Mazur, C. L. Cummins, P. Val, J. Henry-Berger, F. Caira, G. Veyssiere, D. J. Mangelsdorf, and J. M. Lobaccaro. 2004. Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes. Mol. Endocrinol. 18:888-898.
-
(2004)
Mol. Endocrinol
, vol.18
, pp. 888-898
-
-
Volle, D.H.1
Repa, J.J.2
Mazur, A.3
Cummins, C.L.4
Val, P.5
Henry-Berger, J.6
Caira, F.7
Veyssiere, G.8
Mangelsdorf, D.J.9
Lobaccaro, J.M.10
-
59
-
-
0043133791
-
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression
-
Wagner, B. L., A. F. Valledor, G. Shao, C. L. Daige, E. D. Bischoff, M. Petrowski, K. Jepsen, S. H. Baek, R. A. Heyman, M. G. Rosenfeld, I. G. Schulman, and C. K. Glass. 2003. Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol. Cell. Biol. 23:5780-5789.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5780-5789
-
-
Wagner, B.L.1
Valledor, A.F.2
Shao, G.3
Daige, C.L.4
Bischoff, E.D.5
Petrowski, M.6
Jepsen, K.7
Baek, S.H.8
Heyman, R.A.9
Rosenfeld, M.G.10
Schulman, I.G.11
Glass, C.K.12
-
60
-
-
12444256363
-
-
Yoshikawa, T., T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, S. Yatoh, T. Kitamine, H. Okazaki, Y. Tamura, M. Sekiya, A. Takahashi, A. H. Hasty, R. Sato, H. Sone, J. Osuga, S. Ishibashi, and N. Yamada. 2003. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. Mol. Endocrinol. 17:1240-1254.
-
Yoshikawa, T., T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, S. Yatoh, T. Kitamine, H. Okazaki, Y. Tamura, M. Sekiya, A. Takahashi, A. H. Hasty, R. Sato, H. Sone, J. Osuga, S. Ishibashi, and N. Yamada. 2003. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. Mol. Endocrinol. 17:1240-1254.
-
-
-
-
61
-
-
0041353552
-
Cidea-deficient mice have lean phenotype and are resistant to obesity
-
Zhou, Z., S. Yon Toh, Z. Chen, K. Guo, C. P. Ng, S. Ponniah, S. C. Lin, W. Hong, and P. Li. 2003. Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat. Genet. 35:49-56.
-
(2003)
Nat. Genet
, vol.35
, pp. 49-56
-
-
Zhou, Z.1
Yon Toh, S.2
Chen, Z.3
Guo, K.4
Ng, C.P.5
Ponniah, S.6
Lin, S.C.7
Hong, W.8
Li, P.9
|