Stress and aging induce distinct polyQ protein aggregation states

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 26, 2012, Pages 10587-10592

  Moronetti Mazzeo, Lorenza E ^a   Dersh, Devin ^a,b   Boccitto, Marco ^b,c   Kalb, Robert G ^b,c   Lamitina, Todd ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Huntington disease; Osmoregulation; Polyglutamine; Protein homeostasis

Indexed keywords

DAF 2 PROTEIN; POLYGLUTAMINE; PROTEIN; UNCLASSIFIED DRUG;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; CELL STRUCTURE; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING;

AGING; ANIMALS; MICE; OSMOTIC PRESSURE; OXIDATIVE STRESS; PEPTIDES; STRESS, PHYSIOLOGICAL;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 84862991002     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1108766109     Document Type: Article

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