Genome-wide RNAi screening identifies protein damage as a regulator of osmoprotective gene expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 32, 2006, Pages 12173-12178

  Lamitina, Todd ^a,c   Huang, Chunyi George ^b   Strange, Kevin ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Caenorhabditis elegans; Functional genomics; Organic osmolytes; Osmotic stress

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; CHAPERONE; CHAPERONIN; CHEMOKINE RECEPTOR CCR4; COLLAGEN; GLYCEROL; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; HEAT SHOCK PROTEIN 70; HYPOTONIC SOLUTION; INITIATION FACTOR 3; PDZ PROTEIN; PROTEASOME; SMALL NUCLEAR RIBONUCLEOPROTEIN; TUNICAMYCIN;

ARTICLE; CAENORHABDITIS ELEGANS; DELETION MUTANT; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX; FUNCTIONAL GENOMICS; GENE; GENE EXPRESSION; GENE FUNCTION; GPDH 1 GENE; GPDH 2 GENE; HOMEOSTASIS; METABOLISM; NONHUMAN; NORTHERN BLOTTING; NUCLEAR IMPORT; OSMOTIC STRESS; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RNA INTERFERENCE; RNA PROCESSING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRANSGENICS; TRANSLATION INITIATION; WILD TYPE;

ANIMALS; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION; GENETIC TECHNIQUES; GENOMICS; GLYCEROL; GREEN FLUORESCENT PROTEINS; MODELS, GENETIC; OSMOSIS; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; RNA INTERFERENCE;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 33747083190     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0602987103     Document Type: Article

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