Genome-wide RNAi screen and in vivo protein aggregation reporters identify degradation of damaged proteins as an essential hypertonic stress response

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 6, 2008, Pages

  Choe, Keith P ^a   Strange, Kevin ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Caenorhabditis elegans; Cell volume; Kidney; Macromolecular crowding; Polyglutamine

Indexed keywords

POLYGLUTAMINE; PROTEASOME; UBIQUITIN; UREA;

ACCLIMATIZATION; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENDOSOME; GENETIC SCREENING; GENOME ANALYSIS; HYPEROSMOTIC STRESS; LYSOSOME; MACROMOLECULE; MOLECULAR WEIGHT; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN TARGETING; PROTEIN TRANSPORT; RNA INTERFERENCE; SURVIVAL; UBIQUITINATION;

ANIMALS; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GENE EXPRESSION; HYPERTONIC SOLUTIONS; MICROSCOPY, CONFOCAL; OSMOSIS; OSMOTIC PRESSURE; RNA INTERFERENCE; STRESS, PHYSIOLOGICAL;

CAENORHABDITIS ELEGANS;

EID: 57349200362     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00450.2008     Document Type: Article

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