TrkB inhibition as a therapeutic target for CNS-related disorders

Progress in Neurobiology

Volumn 98, Issue 2, 2012, Pages 197-206

  Boulle, Fabien ^a,b   Kenis, Gunter ^a   Cazorla, Maxime ^c   Hamon, Michel ^b   Steinbusch, Harry W M ^a   Lanfumey, Laurence ^b   van den Hove, Daniel L A ^a,d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b INSERM   (France)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

BDNF; Cancer; CNS disorders; Treatments; TrkB inhibitors

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CANNABINOID 1 RECEPTOR; CITALOPRAM; CYCLOTHIAZIDE; DEXAMETHASONE; DOPAMINE 1 RECEPTOR; FLUOXETINE; G PROTEIN COUPLED RECEPTOR; GLUCOCORTICOID; IMIPRAMINE; K 252A; KAINIC ACID; LESTAURTINIB; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID; NERVE GROWTH FACTOR; NEUROTROPHIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; REBOXETINE; TROPOMYOSIN RELATED KINASE RECEPTOR B INHIBITOR; TYROSINE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VOLTAGE GATED CALCIUM CHANNEL;

ADDICTION; ALLODYNIA; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DISEASE; COMPUTER MODEL; CRYSTALLOGRAPHY; DEPRESSION; DIMERIZATION; DISEASE COURSE; DISEASE SEVERITY; DOWN REGULATION; DRUG TARGETING; ENDOSOME; EPILEPSY; EPILEPTOGENESIS; GENE MUTATION; GENETIC ALGORITHM; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; HUMAN; HYPERALGESIA; IMMUNOCYTOCHEMISTRY; MENTAL DISEASE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NEUROPATHIC PAIN; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PATHOGENESIS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REVIEW; SEIZURE; SIGNAL TRANSDUCTION; SYMPTOM; UPREGULATION;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CENTRAL NERVOUS SYSTEM DISEASES; HUMANS; RECEPTOR, TRKB; SIGNAL TRANSDUCTION;

EID: 84862979619     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2012.06.002     Document Type: Review

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