BDNF: A neuromodulator in nociceptive pathways?

Brain Research Reviews

Volumn 40, Issue 1-3, 2002, Pages 240-249

  Pezet, Sophie ^a   Malcangio, Marzia ^a   McMahon, Stephen B ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Centre for Neuroscience Research   (United Kingdom)

Author keywords

Dorsal horn; Neuroplasticity; Neurotrophic factor release; Phospho ERK; Sensory neuron; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ELECTROPHYSIOLOGY; HYPERALGESIA; INFLAMMATION; NERVE STIMULATION; NEUROMODULATION; NEUROPATHIC PAIN; NOCICEPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REVIEW; SECOND MESSENGER; SENSITIZATION; SENSORY NERVE; SPINAL CORD DORSAL HORN; SYNAPSE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; GENE EXPRESSION REGULATION; HUMANS; NEURAL PATHWAYS; NEURONS, AFFERENT; NOCICEPTORS; SYNAPSES;

EID: 0036824741     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(02)00206-0     Document Type: Review

References (60)

1. Abbadie C., Besson J.M. c-fos expression in rat lumbar spinal cord during the development of adjuvant-induced arthritis. Neuroscience. 48:1992;985-993.
2. Abbadie C., Besson J.M. c-fos expression in rat lumbar spinal cord following peripheral stimulation in adjuvant-induced arthritic and normal rats. Brain Res. 607:1993;195-204.
3. Adelson D.W., Wei J.Y., Kruger L. H2O2 sensitivity of afferent splanchnic C fiber units in vitro. J. Neurophysiol. 76:1996;371-380.
4. Adelson D.W., Wei J.Y., Kruger L. Warm-sensitive afferent splanchnic C-fiber units in vitro. J. Neurophysiol. 77:1997;2989-3002.
5. Angleson J.K., Cochilla A.J., Kilic G., Nussinovitch I., Betz W.J. Regulation of dense core release from neuroendocrine cells revealed by imaging single exocytic events. Nat. Neurosci. 2:1999;440-446.
6. Apfel S.C. Neurotrophic factors and pain. Clin. J. Pain. 16:2000;S7-11.
7. Apfel S.C., Wright D.E., Wiideman A.M., Dormia C., Snider W.D., Kessler J.A. Nerve growth factor regulates the expression of brain-derived neurotrophic factor mRNA in the peripheral nervous system. Mol. Cell. Neurosci. 7:1996;134-142.
8. Arvanian V.L., Mendell L.M. Acute modulation of synaptic transmission to motoneurons by BDNF in the neonatal rat spinal cord. Eur. J. Neurosci. 14:2001;1800-1808.
9. Balkowiec A., Katz D.A. Cellular mechanisms underlying activity-dependent release of endogenous BDNF from hippocampal neurons. 31st Annual meeting of the Society for Neuroscience, San Diego, CA:10-15 November 2001.
10. Barakat-Walter I. Brain-derived neurotrophic factor-like immunoreactivity is localized mainly in small sensory neurons of rat dorsal root ganglia. J. Neurosci. Methods. 68:1996;281-288.
11. Bartfai T., Iverfeldt K., Brodin E., Ogren S.O. Functional consequences of coexistence of classical and peptide neurotransmitters. Prog. Brain Res. 68:1986;321-330.
12. Bennett D.L., French J.S., Priestley J.V., McMahon S.B. The effect of BDNF on c-fos and NOS expression in dorsal horn neurons of the adult rat spinal cord. 26th Annual Meeting of the Society for Neuroscience:November 1996.
13. Biffo S., Offenhauser N., Carter B.D., Barde Y.A. Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development. Development. 121:1995;2461-2470.
14. Bradbury E.J., King V.R., Simmons L.J., Priestley J.V., McMahon S.B. NT-3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons. Eur. J. Neurosci. 10:1998;3058-3068.
15. Cho H.J., Kim J.K., Park H.C., Kim J.K., Kim D.S., Ha S.O., Hong H.S. Changes in brain-derived neurotrophic factor immunoreactivity in rat dorsal root ganglia, spinal cord, and gracile nuclei following cut or crush injuries. Exp. Neurol. 154:1998;224-230.
16. Cho H.J., Kim J.K., Zhou X.F., Rush R.A. Increased brain-derived neurotrophic factor immunoreactivity in rat dorsal root ganglia and spinal cord following peripheral inflammation. Brain Res. 764:1997;269-272.
17. Cho H.J., Kim S.Y., Park M.J., Kim D.S., Kim J.K., Chu M.Y. Expression of mRNA for brain-derived neurotrophic factor in the dorsal root ganglion following peripheral inflammation. Brain Res. 749:1997;358-362.
18. De Biasi S., Rustioni A. Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cord. Proc. Natl. Acad. Sci. USA. 85:1988;7820-7824.
19. Di Luca M., Gardoni F., Finardi A., Pagliardini S., Cattabeni F., Battaglia G., Missale C. NMDA receptor subunits are phosphorylated by activation of neurotrophin receptors in PSD of rat spinal cord. Neuroreport. 12:2001;1301-1305.
20. Dickenson A.H. Spinal cord pharmacology of pain. Br. J. Anaesth. 75:1995;193-200.
21. Duggan A.W., Riley R.C., Mark M.A., MacMillan S.J., Schaible H.G. Afferent volley patterns and the spinal release of immunoreactive substance P in the dorsal horn of the anaesthetized spinal cat. Neuroscience. 65:1995;849-858.
22. Eide F.F., Vining E.R., Eide B.L., Zang K., Wang X.Y., Reichardt L.F. Naturally occurring truncated trkB receptors have dominant inhibitory effects on brain-derived neurotrophic factor signaling. J. Neurosci. 16:1996;3123-3129.
23. Fukuoka T., Kondo E., Dai Y., Hashimoto N., Noguchi K. Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model. J. Neurosci. 21:2001;4891-4900.
24. Ha S.O., Kim J.K., Hong H.S., Kim D.S., Cho H.J. Expression of brain-derived neurotrophic factor in rat dorsal root ganglia, spinal cord and gracile nuclei in experimental models of neuropathic pain. Neuroscience. 107:2001;301-309.
25. Haapasalo A., Koponen E., Hoppe E., Wong G., Castren E. Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival. Biochem. Biophys. Res. Commun. 280:2001;1352-1358.
26. Han W., Li D., Stout A.K., Takimoto K., Levitan E.S. Ca2+-induced deprotonation of peptide hormones inside secretory vesicles in preparation for release. J. Neurosci. 19:1999;900-905.
27. Heppenstall P.A., Lewin G.R. BDNF but not NT-4 is required for normal flexion reflex plasticity and function. Proc. Natl. Acad. Sci. USA. 98:2001;8107-8112.
28. Ji R.R., Baba H., Brenner G.J., Woolf C.J. Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat. Neurosci. 2:1999;1114-1119.
29. Ji R.R., Befort K., Brenner G.J., Woolf C.J. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J. Neurosci. 22:2002;478-485.
30. Josephson A., Widenfalk J., Trifunovski A., Widmer H.R., Olson L., Spenger C. GDNF and NGF family members and receptors in human fetal and adult spinal cord and dorsal root ganglia. J. Comp Neurol. 440:2001;204-217.
31. Kang H., Welcher A.A., Shelton D., Schuman E.M. Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron. 19:1997;653-664.
32. Kerr B.J., Bradbury E.J., Bennett D.L., Trivedi P.M., Dassan P., French J., Shelton D.B., McMahon S.B., Thompson S.W. Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord. J. Neurosci. 19:1999;5138-5148.
33. King V.R., Bradbury E.J., McMahon S.B., Priestley J.V. Changes in truncated trkB and p75 receptor expression in the rat spinal cord following spinal cord hemisection and spinal cord hemisection plus neurotrophin treatment. Exp. Neurol. 165:2000;327-341.
34. Langley K., Grant N.J. Are exocytosis mechanisms neurotransmitter specific? Neurochem. Int. 31:1997;739-757.
35. Lee S.L., Kim J.K., Kim D.S., Cho H.J. Expression of mRNAs encoding full-length and truncated TrkB receptors in rat dorsal root ganglia and spinal cord following peripheral inflammation. Neuroreport. 10:1999;2847-2851.
36. Lever I.J., Bradbury E.J., Cunningham J.R., Adelson D.W., Jones M.G., McMahon S.B., Marvizon J.C., Malcangio M. Brain-derived neurotrophic factor is released in the dorsal horn by distinctive patterns of afferent fiber stimulation. J. Neurosci. 21:2001;4469-4477.
37. Levine E.S., Crozier R.A., Black I.B., Plummer M.R. Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity. Proc. Natl. Acad. Sci. USA. 95:1998;10235-10239.
38. Levine E.S., Kolb J.E. Brain-derived neurotrophic factor increases activity of NR2B-containing N-methyl-D-aspartate receptors in excised patches from hippocampal neurons. J. Neurosci. Res. 62:2000;357-362.
39. Liebl D.J., Huang W., Young W., Parada L.F. Regulation of Trk receptors following contusion of the rat spinal cord. Exp. Neurol. 167:2001;15-26.
40. Lin S.Y., Wu K., Levine E.S., Mount H.T., Suen P.C., Black I.B. BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities. Brain Res. Mol. Brain Res. 55:1998;20-27.
41. Luo X., Rush R.A., Zhou X. Ultrastructural localization of brain-derived neurotrophic factor in rat primary sensory neurons. Neurosci. Res. 39:2001;377-384.
42. Mannion R.J., Costigan M., Decosterd I., Amaya F., Ma Q.P., Holstege J.C., Ji R.R., Acheson A., Lindsay R.M., Wilkinson G.A., Woolf C.J. Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc. Natl. Acad. Sci. U.SA. 96:1999;9385-9390.
43. Marvizon J.C., Martinez V., Grady E.F., Bunnett N.W., Mayer E.A. Neurokinin 1 receptor internalization in spinal cord slices induced by dorsal root stimulation is mediated by NMDA receptors. J. Neurosci. 17:1997;8129-8136.
44. Meyer-Franke A., Wilkinson G.A., Kruttgen A., Hu M., Munro E., Hanson M.G. Jr., Reichardt L.F., Barres B.A. Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons. Neuron. 21:1998;681-693.
45. Michael G.J., Averill S., Nitkunan A., Rattray M., Bennett D.L., Yan Q., Priestley J.V. Nerve growth factor treatment increases brain-derived neurotrophic factor selectively in TrkA-expressing dorsal root ganglion cells and in their central terminations within the spinal cord. J. Neurosci. 17:1997;8476-8490.
46. Narita M., Yajima Y., Aoki T., Ozaki S., Mizoguchi H., Tseng L.F., Suzuki T. Up-regulation of the TrkB receptor in mice injured by the partial ligation of the sciatic nerve. Eur. J. Pharmacol. 401:2000;187-190.
47. Pan W., Banks W.A., Fasold M.B., Bluth J., Kastin A.J. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology. 37:1998;1553-1561.
48. Pezet S., Lever I., Malcangio M., Williams R.J., McMahon S.B. Nociceptive stimulation induces TrkB receptor phosphorylation in the rat dorsal horn. 31st Annual Meeting of the Society for Neuroscience, San Diego, CA:10-15 November 2001.
49. Shelton D.L., Sutherland J., Gripp J., Camerato T., Armanini M.P., Phillips H.S., Carroll K., Spencer S.D., Levinson A.D. Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins. J. Neurosci. 15:1995;477-491.
50. Slack S., Pezet S., Malcangio M., Thompson S.W.N. BDNF induces NMDA receptor subunit 1 phosphorylation in rat dorsal horn neurons. 31st Annual Meeting of the Society for Neuroscience, San Diego, CA:10-15 November 2001.
51. Small D.L., Murray C.L., Mealing G.A., Poulter M.O., Buchan A.M., Morley P. Brain derived neurotrophic factor induction of N-methyl-D-aspartate receptor subunit NR2A expression in cultured rat cortical neurons. Neurosci. Lett. 252:1998;211-214.
52. Snider W.D., McMahon S.B. Tackling pain at the source: new ideas about nociceptors. Neuron. 20:1998;629-632.
53. Thompson S.W., Bennett D.L., Kerr B.J., Bradbury E.J., McMahon S.B. Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord. Proc. Natl. Acad. Sci. USA. 96:1999;7714-7718.
54. Urban L., Thompson S.W., Dray A. Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci. 17:1994;432-438.
55. Wetmore C., Olson L. Neuronal and nonneuronal expression of neurotrophins and their receptors in sensory and sympathetic ganglia suggest new intercellular trophic interactions. J. Comp. Neurol. 353:1995;143-159.
56. Yan Q., Radeke M.J., Matheson C.R., Talvenheimo J., Welcher A.A., Feinstein S.C. Immunocytochemical localization of TrkB in the central nervous system of the adult rat. J. Comp. Neurol. 378:1997;135-157.
57. Yan Q., Rosenfeld R.D., Matheson C.R., Hawkins N., Lopez O.T., Bennett L., Welcher A.A. Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system. Neuroscience. 78:1997;431-448.
58. Zhou X.F., Chie E.T., Deng Y.S., Zhong J.H., Xue Q., Rush R.A., Xian C.J. Injured primary sensory neurons switch phenotype for brain-derived neurotrophic factor in the rat. Neuroscience. 92:1999;841-853.
59. Zhou X.F., Parada L.F., Soppet D., Rush R.A. Distribution of trkB tyrosine kinase immunoreactivity in the rat central nervous system. Brain Res. 622:1993;63-70.
60. Zhou X.F., Rush R.A. Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons. Neuroscience. 74:1996;945-953.