Functional screening of cytochrome P450 activity and uncoupling by capillary electrophoresis

Analytical Chemistry

Volumn 84, Issue 2, 2012, Pages 862-866

  Harskamp, James ^a   Britz Mckibbin, Philip ^a   Wilson, Joanna Y ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC CYCLES; COUPLED REACTION; COUPLING EFFICIENCY; CYTOCHROME P450; DANIO RERIO; FLUORESCENT PRODUCTS; FLUOROGENIC SUBSTRATE; FUNCTIONAL SCREENING; ISOFORMS; MONOOXYGENASES; O-DEALKYLATION; RAPID ASSESSMENT; REACTIVE OXYGEN SPECIES; SUBSTRATE BINDING; SUBSTRATE INTERACTION; UV DETECTION; XENOBIOTIC COMPOUNDS; XENOBIOTIC METABOLISM; ZEBRAFISH;

CAPILLARY ELECTROPHORESIS; EFFICIENCY; HYDROGEN; HYDROGEN PEROXIDE; SUBSTRATES;

CATALYST ACTIVITY;

CYTOCHROME P450; CYTOCHROME P450, FAMILY 1, SUBFAMILY B, POLYPEPTIDE 1; ESTRADIOL; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN; UNSPECIFIC MONOOXYGENASE;

ANIMAL; ARTICLE; CAPILLARY ELECTROPHORESIS; CATALYSIS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; OXIDATION REDUCTION REACTION; ZEBRA FISH;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROPHORESIS, CAPILLARY; ESTRADIOL; HYDROGEN PEROXIDE; NADP; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; UNCOUPLING AGENTS; ZEBRAFISH;

EID: 84862954530     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac202787n     Document Type: Article

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