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Volumn 505, Issue 2, 2011, Pages 186-193

Simultaneous measurement of CYP1A2 activity, regioselectivity, and coupling: Implications for environmental sensitivity of enzyme-substrate binding

(3) Traylor, Matthew J a Chai, Jack a Clark, Douglas S a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Cyanocoumarin; CYP1A2; P450 coupling; P450 regioselectivity

Indexed keywords

7 ETHOXYMETHOXY 3 CYANOCOUMARIN; COUMARIN DERIVATIVE; CYTOCHROME P450 1A2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DEALKYLATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; IONIC STRENGTH; PH MEASUREMENT; PRIORITY JOURNAL; TEMPERATURE MEASUREMENT;

ANIMALS; BUFFERS; COUMARINS; CYTOCHROME P-450 CYP1A2; HUMANS; HYDROGEN-ION CONCENTRATION; NADP; OSMOLAR CONCENTRATION; OXIDATION-REDUCTION; PROTEIN BINDING; RABBITS; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 78651249554 PISSN: 00039861 EISSN: 10960384 Source Type: Journal
DOI: 10.1016/j.abb.2010.10.002 Document Type: Article

Times cited : (5)

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