-
1
-
-
52449121246
-
Novel insights in chronic lymphocytic leukemia: Are we getting closer to understanding the pathogenesis of the disease?
-
Caligaris-Cappio F, Ghia P. Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease? J Clin Oncol. 2008;26(27):4497-4503.
-
(2008)
J Clin Oncol
, vol.26
, Issue.27
, pp. 4497-4503
-
-
Caligaris-Cappio, F.1
Ghia, P.2
-
2
-
-
36148983111
-
Emerging therapy for chronic lymphocytic leukaemia
-
DOI 10.1111/j.1365-2141.2007.06877.x
-
Auer RL, Gribben J, Cotter FE. Emerging therapy for chronic lymphocytic leukaemia. Br J Haematol. 2007;139(5):635-644. (Pubitemid 350115738)
-
(2007)
British Journal of Haematology
, vol.139
, Issue.5
, pp. 635-644
-
-
Auer, R.L.1
Gribben, J.2
Cotter, F.E.3
-
4
-
-
0033377032
-
Adhesion to bone marrow stroma inhibits apoptosis of chronic lymphocytic leukemia cells
-
Lagneaux L, Delforge A, De Bruyn C, Bernier M, Bron D. Adhesion to bone marrow stroma inhibits apoptosis of chronic lymphocytic leukemia cells. Leuk Lymphoma. 1999;35(5-6):445-453. (Pubitemid 30015644)
-
(1999)
Leukemia and Lymphoma
, vol.35
, Issue.5-6
, pp. 445-453
-
-
Lagneaux, L.1
Delforge, A.2
De Bruyn, C.3
Bernier, M.4
Bron, D.5
-
5
-
-
0030048565
-
Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro
-
Panayiotidis P, Jones D, Ganeshaguru K, Foroni L, Hoffbrand AV. Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. Br J Haematol. 1996;92(1):97-103. (Pubitemid 26018774)
-
(1996)
British Journal of Haematology
, vol.92
, Issue.1
, pp. 97-103
-
-
Panayiotidis, P.1
Jones, D.2
Ganeshaguru, K.3
Foroni, L.4
Hoffbrand, A.V.5
-
6
-
-
73349126115
-
Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: Development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance
-
Kurtova A, Balakrishnan K, Chen R, et al. Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. Blood. 2009;114(20):4441-4450.
-
(2009)
Blood
, vol.114
, Issue.20
, pp. 4441-4450
-
-
Kurtova, A.1
Balakrishnan, K.2
Chen, R.3
-
7
-
-
0034667624
-
Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
-
Burger JA, Tsukada N, Burger M, Zvaifler NJ, Dell'Aquila M, Kipps TJ. Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood. 2000;96(8):2655-2663.
-
(2000)
Blood
, vol.96
, Issue.8
, pp. 2655-2663
-
-
Burger, J.A.1
Tsukada, N.2
Burger, M.3
Zvaifler, N.J.4
Dell'Aquila, M.5
Kipps, T.J.6
-
8
-
-
0036720390
-
Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1
-
Pedersen IM, Kitada S, Leoni LM, et al. Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1. Blood. 2002; 100(5):1795-1801. (Pubitemid 34925159)
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1795-1801
-
-
Pedersen, I.M.1
Kitada, S.2
Leoni, L.M.3
Zapata, J.M.4
Karras, J.G.5
Tsukada, N.6
Kipps, T.J.7
Choi, Y.S.8
Bennett, F.9
Reed, J.C.10
-
9
-
-
59449095496
-
AT-101 induces apoptosis in CLL B-cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance
-
Balakrishnan K, Burger JA, Wierda WG, Gandhi V. AT-101 induces apoptosis in CLL B-cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. Blood. 2009;113(1): 149-153.
-
(2009)
Blood
, vol.113
, Issue.1
, pp. 149-153
-
-
Balakrishnan, K.1
Burger, J.A.2
Wierda, W.G.3
Gandhi, V.4
-
10
-
-
0034051534
-
The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms
-
Ghia P, Caligaris-Cappio F. The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms. Adv Cancer Res. 2000;79:157-173. (Pubitemid 30228123)
-
(2000)
Advances in Cancer Research
, vol.79
, pp. 157-173
-
-
Ghia, P.1
Caligaris-Cappio, F.2
-
11
-
-
11444259307
-
Microenvironmental interactions and survival of CLL B-cells
-
DOI 10.1080/10428190412331272703
-
Munk Pedersen I, Reed J. Microenvironmental interactions and survival of CLL B-cells. Leuk Lymphoma. 2004;45(12):2365-2372. (Pubitemid 40081179)
-
(2004)
Leukemia and Lymphoma
, vol.45
, Issue.12
, pp. 2365-2372
-
-
Pedersen, I.M.1
Reed, J.C.2
-
13
-
-
33644845081
-
Microenvironmental niches in the bone marrow required for B-cell development
-
DOI 10.1038/nri1780, PII N1780
-
Nagasawa T. Microenvironmental niches in the bone marrow required for B-cell development. Nat Rev Immunol. 2006;6(2):107-116. (Pubitemid 43361586)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.2
, pp. 107-116
-
-
Nagasawa, T.1
-
14
-
-
58149175555
-
The life of a cell: Apoptosis regulation by the PI3K/PKB pathway
-
Duronio V. The life of a cell: apoptosis regulation by the PI3K/PKB pathway. Biochem J. 2008; 415(3):333-344.
-
(2008)
Biochem J
, vol.415
, Issue.3
, pp. 333-344
-
-
Duronio, V.1
-
15
-
-
59849098801
-
Phosphatidylinositol 3-kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells
-
Su CC, Lin YP, Cheng YJ, et al. Phosphatidylinositol 3-kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells. J Immunol. 2007;179(7):4589-4597.
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4589-4597
-
-
Su, C.C.1
Lin, Y.P.2
Cheng, Y.J.3
-
16
-
-
38349107623
-
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
-
Longo PG, Laurenti L, Gobessi S, Sica S, Leone G, Efremov DG. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells. Blood. 2008;111(2): 846-855.
-
(2008)
Blood
, vol.111
, Issue.2
, pp. 846-855
-
-
Longo, P.G.1
Laurenti, L.2
Gobessi, S.3
Sica, S.4
Leone, G.5
Efremov, D.G.6
-
17
-
-
0035846955
-
Cd19-dependent activation of Akt kinase in B-lymphocytes
-
Otero DC, Omori SA, Rickert RC. Cd19-dependent activation of Akt kinase in B-lymphocytes. J Biol Chem. 2001;276(2):1474-1478.
-
(2001)
J Biol Chem
, vol.276
, Issue.2
, pp. 1474-1478
-
-
Otero, D.C.1
Omori, S.A.2
Rickert, R.C.3
-
18
-
-
0031936619
-
Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes
-
Gringhuis SI, de Leij LF, Coffer PJ, Vellenga E. Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes. Mol Cell Biol. 1998;18(3):1725-1735. (Pubitemid 28100938)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.3
, pp. 1725-1735
-
-
Gringhuis, S.I.1
De Leij, L.F.M.H.2
Coffer, P.J.3
Vellenga, E.4
-
19
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2(7):489-501. (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
20
-
-
68249128423
-
Insights into the PI3-KPKB- MTOR signalling pathway from small molecules
-
Gunn RM, Hailes HC. Insights into the PI3-KPKB- mTOR signalling pathway from small molecules. J Chem Biol. 2008;1(1-4):49-62.
-
(2008)
J Chem Biol
, vol.1
, Issue.1-4
, pp. 49-62
-
-
Gunn, R.M.1
Hailes, H.C.2
-
21
-
-
70349391226
-
Advances in development of phosphatidylinositol 3-kinase inhibitors
-
Kong D, Yamori T. Advances in development of phosphatidylinositol 3-kinase inhibitors. Curr Med Chem. 2009;16(22):2839-2854.
-
(2009)
Curr Med Chem
, vol.16
, Issue.22
, pp. 2839-2854
-
-
Kong, D.1
Yamori, T.2
-
22
-
-
51849084360
-
The PTEN-PI3K pathway: Of feedbacks and cross-talks
-
Carracedo A, Pandolfi PP. The PTEN-PI3K pathway: of feedbacks and cross-talks. Oncogene. 2008;27(41):5527-5541.
-
(2008)
Oncogene
, vol.27
, Issue.41
, pp. 5527-5541
-
-
Carracedo, A.1
Pandolfi, P.P.2
-
23
-
-
0038549067
-
PI3K in lymphocyte development, differentiation and activation
-
Okkenhaug K, Vanhaesebroeck B. PI3K in lymphocyte development, differentiation and activation. Nat Rev Immunol. 2003;3(4):317-330. (Pubitemid 37328684)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.4
, pp. 317-330
-
-
Okkenhaug, K.1
Vanhaesebroeck, B.2
-
24
-
-
4344664011
-
A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells
-
DOI 10.1038/sj.leu.2403398
-
Cuni S, Perez-Aciego P, Perez-Chacon G, et al. A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells. Leukemia. 2004;18(8):1391-1400. (Pubitemid 39136749)
-
(2004)
Leukemia
, vol.18
, Issue.8
, pp. 1391-1400
-
-
Cuni, S.1
Perez-Aciego, P.2
Perez-Chacon, G.3
Vargas, J.A.4
Sanchez, A.5
Martin-Saavedra, F.M.6
Ballester, S.7
Garcia-Marco, J.8
Jorda, J.9
Durantez, A.10
-
25
-
-
0037111661
-
Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: Association with protein kinase Cdelta
-
DOI 10.1182/blood-2002-02-0539
-
Ringshausen I, Schneller F, Bogner C, et al. Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta. Blood. 2002;100(10):3741-3748. (Pubitemid 35303946)
-
(2002)
Blood
, vol.100
, Issue.10
, pp. 3741-3748
-
-
Ringshausen, I.1
Schneller, F.2
Bogner, C.3
Hipp, S.4
Duyster, J.5
Peschel, C.6
Decker, T.7
-
26
-
-
0034791463
-
Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia cells
-
DOI 10.1046/j.1365-2141.2001.02978.x
-
Wickremasinghe RG, Ganeshaguru K, Jones DT, et al. Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in Bchronic lymphocytic leukaemia cells. Br J Haematol. 2001;114(3):608-615. (Pubitemid 32953639)
-
(2001)
British Journal of Haematology
, vol.114
, Issue.3
, pp. 608-615
-
-
Wickremasinghe, R.G.1
Ganeshaguru, K.2
Jones, D.T.3
Lindsay, C.4
Spanswick, V.J.5
Hartley, J.A.6
Wadhwa, M.7
Thorpe, R.8
Hoffbrand, A.V.9
Prentice, H.G.10
Mehta, A.B.11
-
27
-
-
33845526567
-
The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease
-
DOI 10.1038/sj.leu.2404417, PII 2404417
-
Longo PG, Laurenti L, Gobessi S, et al. The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease. Leukemia. 2007;21(1):110-120. (Pubitemid 44921842)
-
(2007)
Leukemia
, vol.21
, Issue.1
, pp. 110-120
-
-
Longo, P.G.1
Laurenti, L.2
Gobessi, S.3
Petlickovski, A.4
Pelosi, M.5
Chiusolo, P.6
Sica, S.7
Leone, G.8
Efremov, D.G.9
-
28
-
-
67049137382
-
Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: A novel therapeutic approach
-
Niedermeier M, Hennessy BT, Knight ZA, et al. Isoform-selective phosphoinositide 3′-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach. Blood. 2009;113(22):5549-5557.
-
(2009)
Blood
, vol.113
, Issue.22
, pp. 5549-5557
-
-
Niedermeier, M.1
Hennessy, B.T.2
Knight, Z.A.3
-
29
-
-
0032080433
-
Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin
-
Christodoulopoulos G, Muller C, Salles B, Kazmi R, Panasci L. Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin. Cancer Res. 1998;58(9): 1789-1792. (Pubitemid 28217447)
-
(1998)
Cancer Research
, vol.58
, Issue.9
, pp. 1789-1792
-
-
Christodoulopoulos, G.1
Muller, C.2
Salles, B.3
Kazmi, R.4
Panasci, L.5
-
30
-
-
85047690320
-
TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia
-
DOI 10.1172/JCI200419540
-
Shehata M, Schwarzmeier JD, Hilgarth M, Hubmann R, Duechler M, Gisslinger H. TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia. J Clin Invest. 2004;113(5): 676-685. (Pubitemid 38544160)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.5
, pp. 676-685
-
-
Shehata, M.1
Schwarzmeier, J.D.2
Hilgarth, M.3
Hubmann, R.4
Duechler, M.5
Gisslinger, H.6
-
31
-
-
33947218937
-
Covalent Reactions of Wortmannin under Physiological Conditions
-
DOI 10.1016/j.chembiol.2007.02.007, PII S1074552107000749
-
Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L. Covalent reactions of wortmannin under physiological conditions. Chem Biol. 2007; 14(3):321-328. (Pubitemid 46428147)
-
(2007)
Chemistry and Biology
, vol.14
, Issue.3
, pp. 321-328
-
-
Yuan, H.1
Barnes, K.R.2
Weissleder, R.3
Cantley, L.4
Josephson, L.5
-
32
-
-
42249098543
-
Oncogenic signaling of class I PI3K isoforms
-
DOI 10.1038/sj.onc.1210918, PII 1210918
-
Denley A, Kang S, Karst U, Vogt PK. Oncogenic signaling of class I PI3K isoforms. Oncogene. 2008;27(18):2561-2574. (Pubitemid 351550883)
-
(2008)
Oncogene
, vol.27
, Issue.18
, pp. 2561-2574
-
-
Denley, A.1
Kang, S.2
Karst, U.3
Vogt, P.K.4
-
34
-
-
0033199841
-
Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: Identification of five sites of phosphorylation in vivo
-
DOI 10.1042/0264-6021:3420287
-
Casamayor A, Morrice NA, Alessi DR. Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo. Biochem J. 1999;342(Pt 2):287-292. (Pubitemid 29425348)
-
(1999)
Biochemical Journal
, vol.342
, Issue.2
, pp. 287-292
-
-
Casamayor, A.1
Morrice, N.A.2
Alessi, D.R.3
-
35
-
-
0033946740
-
Phosphorylation of the PTEN tail regulates protein stability and function
-
DOI 10.1128/MCB.20.14.5010-5018.2000
-
Vazquez F, Ramaswamy S, Nakamura N, Sellers WR. Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol. 2000; 20(14):5010-5018. (Pubitemid 30431555)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.14
, pp. 5010-5018
-
-
Vazquez, F.1
Ramaswamy, S.2
Nakamura, N.3
Sellers, W.R.4
-
36
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
-
DOI 10.1074/jbc.M009134200
-
Torres J, Pulido R. The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome- mediated degradation. J Biol Chem. 2001;276(2):993-998. (Pubitemid 32096519)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.2
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
37
-
-
0037269847
-
Protein kinase CK2: Structure, regulation and role in cellular decisions of life and death
-
Litchfield DW. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J. 2003;369(Pt 1):1-15.
-
(2003)
Biochem J
, vol.369
, Issue.PART 1
, pp. 1-15
-
-
Litchfield, D.W.1
-
38
-
-
0037174166
-
Direct identification of PTEN phosphorylation sites
-
Miller SJ, Lou DY, Seldin DC, Lane WS, Neel BG. Direct identification of PTEN phosphorylation sites. FEBS Lett. 2002;528(1-3):145-153.
-
(2002)
FEBS Lett
, vol.528
, Issue.1-3
, pp. 145-153
-
-
Miller, S.J.1
Lou, D.Y.2
Seldin, D.C.3
Lane, W.S.4
Neel, B.G.5
-
39
-
-
0032572792
-
DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site
-
Blaydes JP, Hupp TR. DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site. Oncogene. 1998;17(8):1045-1052.
-
(1998)
Oncogene
, vol.17
, Issue.8
, pp. 1045-1052
-
-
Blaydes, J.P.1
Hupp, T.R.2
-
40
-
-
0035805108
-
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2')
-
DOI 10.1016/S0014-5793(01)02404-8, PII S0014579301024048
-
Sarno S, Reddy H, Meggio F, et al. Selectivity of 4,5,6,7- tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2′). FEBS Lett. 2001;496(1):44-48. (Pubitemid 32436419)
-
(2001)
FEBS Letters
, vol.496
, Issue.1
, pp. 44-48
-
-
Sarno, S.1
Reddy, H.2
Meggio, F.3
Ruzzene, M.4
Davies, S.P.5
Donella-Deana, A.6
Shugar, D.7
Pinna, L.A.8
-
41
-
-
20044377997
-
Protein kinase CK2 phosphorylates and upregulates Akt/PKB
-
DOI 10.1038/sj.cdd.4401604
-
Di Maira G, Salvi M, Arrigoni G, et al. Protein kinase CK2 phosphorylates and upregulates Akt/ PKB. Cell Death Differ. 2005;12(6):668-677. (Pubitemid 40767169)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.6
, pp. 668-677
-
-
Di Maira, G.1
Salvi, M.2
Arrigoni, G.3
Marin, O.4
Sarno, S.5
Brustolon, F.6
Pinna, L.A.7
Ruzzene, M.8
-
42
-
-
66149141021
-
PTEN and the PI3-kinase pathway in cancer
-
Chalhoub N, Baker SJ. PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol. 2009;4:127-150.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 127-150
-
-
Chalhoub, N.1
Baker, S.J.2
-
43
-
-
0037393911
-
Disparate expression of the PTEN gene: A novel finding in B-cell chronic lymphocytic leukaemia (B-CLL)
-
DOI 10.1046/j.1365-2141.2003.04227.x
-
Leupin N, Cenni B, Novak U, et al. Disparate expression of the PTEN gene: a novel finding in Bcell chronic lymphocytic leukaemia (B-CLL). Br J Haematol. 2003;121(1):97-100. (Pubitemid 36461273)
-
(2003)
British Journal of Haematology
, vol.121
, Issue.1
, pp. 97-100
-
-
Leupin, N.1
Cenni, B.2
Novak, U.3
Hugli, B.4
Graber, H.U.5
Tobler, A.6
Fey, M.F.7
-
44
-
-
38349030742
-
New insights into PTEN
-
Tamguney T, Stokoe D. New insights into PTEN. J Cell Sci. 2007;120(Pt 23):4071-4079.
-
(2007)
J Cell Sci
, vol.120
, Issue.PART 23
, pp. 4071-4079
-
-
Tamguney, T.1
Stokoe, D.2
-
45
-
-
24944568790
-
Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis
-
DOI 10.1158/0008-5472.CAN-05-1888
-
Chung JH, Eng C. Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis. Cancer Res. 2005;65(18):8096-8100. (Pubitemid 41330571)
-
(2005)
Cancer Research
, vol.65
, Issue.18
, pp. 8096-8100
-
-
Chung, J.-H.1
Eng, C.2
-
46
-
-
0036644058
-
Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation
-
Birle D, Bottini N, Williams S, et al. Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation. J Immunol. 2002;169(1):286-291. (Pubitemid 34686147)
-
(2002)
Journal of Immunology
, vol.169
, Issue.1
, pp. 286-291
-
-
Birle, D.1
Bottini, N.2
Williams, S.3
Huynh, H.4
DeBelle, I.5
Adamson, E.6
Mustelin, T.7
-
47
-
-
55849138418
-
PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability
-
Silva A, Yunes JA, Cardoso BA, et al. PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability. J Clin Invest. 2008;118(11):3762-3774.
-
(2008)
J Clin Invest
, vol.118
, Issue.11
, pp. 3762-3774
-
-
Silva, A.1
Yunes, J.A.2
Cardoso, B.A.3
-
48
-
-
70350734809
-
The microenvironment in mature B-cell malignancies: A target for new treatment strategies
-
Burger J, Ghia P, Rosenwald A, Caligaris-Cappio F. The microenvironment in mature B-cell malignancies: a target for new treatment strategies. Blood. 2009;114(16):3367-3375.
-
(2009)
Blood
, vol.114
, Issue.16
, pp. 3367-3375
-
-
Burger, J.1
Ghia, P.2
Rosenwald, A.3
Caligaris-Cappio, F.4
-
49
-
-
55249096769
-
Protein kinase CK2 inhibitors: Emerging anticancer therapeutic agents?
-
Bortolato A, Cozza G, Moro S. Protein kinase CK2 inhibitors: emerging anticancer therapeutic agents? Anticancer Agents Med Chem. 2008; 8(7):798-806.
-
(2008)
Anticancer Agents Med Chem
, vol.8
, Issue.7
, pp. 798-806
-
-
Bortolato, A.1
Cozza, G.2
Moro, S.3
-
50
-
-
43749120732
-
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications
-
DOI 10.2174/156800908784293659
-
Carnero A, Blanco-Aparicio C, Renner O, Link W, Leal JF. The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Curr Cancer Drug Targets. 2008;8(3):187-198. (Pubitemid 351688437)
-
(2008)
Current Cancer Drug Targets
, vol.8
, Issue.3
, pp. 187-198
-
-
Carnero, A.1
Blanco-Aparicio, C.2
Renner, O.3
Link, W.4
Leal, J.F.M.5
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