Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells

Life Sciences

Volumn 76, Issue 12, 2005, Pages 1367-1379

  Zheng, Pei Wen ^a   Chiang, Lien Chai ^a   Lin, Chun Ching ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apigenin; Apoptosis; Bcl 2; Caspase 3; Fas; p21; p53

Indexed keywords

APIGENIN; CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA FRAGMENT; FAS ANTIGEN; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE G1 PHASE; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; DRUG STRUCTURE; FEMALE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; IC 50; MITOSIS INHIBITION; PROTEIN EXPRESSION; UPREGULATION; UTERINE CERVIX CARCINOMA;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APIGENIN; APOPTOSIS; CASPASE 3; CASPASES; CELL CYCLE; CELL SURVIVAL; DNA FRAGMENTATION; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HELA CELLS; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 12744276051     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.08.023     Document Type: Article

References (39)

1. M.L. Agarwal, A. Agarwal, W.R. Taylor, and G.R. Stark p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts Proceedings of the National Academy of Sciences of the United States of America 92 1995 8493 8497
2. M.L. Agarwal, W.R. Taylor, M.V. Chernov, O.B. Chernova, and G.R. Stark The p53 network The Journal of Biological Chemistry 273 1998 1 4
3. R.T. Allen, W.J. Hunter III, and D.K. Agrawal Morphological and biochemical characterization and analysis of apoptosis Journal of Pharmacological and Toxicological Methods 37 1997 215 228
4. C.H. Chen, L.L. Huang, C.C. Huang, C.C. Lin, Y. Lee, and F.J. Lu Baicalein, a novel apoptotic agent for hepatoma cell lines: a potential medicine for hepatoma Nutrition and Cancer 38 2000 287 295
5. J. Cheng, T. Zhou, C. Liu, J.P. Shapiro, M.J. Brauer, M.C. Kiefer, P.J. Barr, and J.D. Mountz Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule Science 263 1994 1759 1762
6. G. Duthie, and A. Crozier Plant-derived phenolic antioxidants Current Opinion in Clinical Nutrition and Metabolic Care 3 2000 447 451
7. E.J. Fuchs, K.A. McKenna, and A. Bedi p53-dependent DNA damage-induced apoptosis requires Fas/APO-1-independent activation of CPP32beta Cancer Research 57 1997 2550 2554
8. K.H. Gan, Y.F. Fann, S.H. Hsu, K.W. Kuo, and C.N. Lin Mediation of the cytotoxicity of lanostanoids and steroids of Ganoderma tsugae through apoptosis and cell cycle Journal of Natural Products 61 1998 485 487
9. T. Glaser, B. Wagenknecht, and M. Weller Identification of p21 as a target of cycloheximide-mediated facilitation of CD95-mediated apoptosis in human malignant glioma cells Oncogene 20 2001 4757 4767
10. C.J. Goodwin, S.J. Holt, S. Downes, and N.J. Marshall Microculture tetrazolium assays: a comparison between two new tetrazolium salts, XTT and MTS Journal of Immunological Methods 179 1995 95 103
11. K. Hastak, S. Gupta, N. Ahmad, M.K. Agarwal, M.L. Agarwal, and H. Mukhtar Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells Oncogene 22 2003 4851 4859
12. D.M. Hockenbery, Z.N. Oltvai, X.M. Yin, C.L. Milliman, and S.J. Korsmeyer Bcl-2 functions in an antioxidant pathway to prevent apoptosis Cell 75 1993 241 251
13. C. Huang, W.Y. Ma, J. Li, S.S. Hecht, and Z. Dong Essential role of p53 in phenethyl isothiocyanate-induced apoptosis Cancer Research 58 1998 4102 4106
14. C. Huang, W.Y. Ma, A. Goranson, and Z. Dong Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway Carcinogenesis 20 1999 237 242
15. K. Kannan, N. Amariglio, G. Rechavi, J. Jakob-Hirsch, I. Kela, N. Kaminski, G. Getz, E. Domany, and D. Givol DNA microarrays identification of primary and secondary target genes regulated by p53 Oncogene 20 2001 2225 2234
16. M.B. Kastan, O. Onyekwere, D. Sidransky, B. Vogelstein, and R.W. Craig Participation of p53 protein in the cellular response to DNA damage Cancer Research 51 1991 6304 6311
17. H.P. Kim, I. Mani, L. Iversen, and V.A. Ziboh Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea-pigs Prostaglandins, Leukotrienes, and Essential Fatty Acids 58 1998 17 24
18. W.R. Lee, S.C. Shen, H.Y. Lin, W.C. Hou, L.L. Yang, and Y.C. Chen Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease Biochemical Pharmacology 63 2002 225 236
19. D.M. Lepley, and J.C. Pelling Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin Molecular Carcinogenesis 19 1997 74 82
20. P. May, and E. May Twenty years of p53 research: structural and functional aspects of the p53 protein Oncogene 18 1999 7621 7636
21. M. McVean, H. Xiao, K. Isobe, and J.C. Pelling Increase in wild-type p53 stability and transactivational activity by the chemopreventive agent apigenin in keratinocytes Carcinogenesis 21 2000 633 639
22. M.D. Mediavilla, S. Cos, and E.J. Sanchez-Barcelo Melatonin increases p53 and p21WAF1 expression in MCF-7 human breast cancer cells in vitro Life Science 65 1999 415 420
23. D. Michalovitz, O. Halevy, and M. Oren Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53 Cell 62 1990 671 680
24. D. Munsch, R. Watanabe-Fukunaga, J.C. Bourdon, S. Nagata, E. May, E. Yonish-Rouach, and P. Reisdorf Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis The Journal of Biological Chemistry 275 2000 3867 3872
25. B. Pucci, M. Kasten, and A. Giordano Cell cycle and apoptosis Neoplasia 2 2000 291 299
26. J.C. Reed Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance Current Opinion in Oncology 7 1995 541 546
27. F. Sato, Y. Matsukawa, K. Matsumoto, H. Nishino, and T. Sakai Apigenin induces morphological differentiation and G2-M arrest in rat neuronal cells Biochemical and Biophysical Research Communications 204 1994 578 584
28. J.L. Schwartz In vitro growth changes of oral human keratinocytes after treatment with carotenoids, retinoid, and/or DMBA Nutrition and Cancer 33 1999 58 68
29. D.A. Scudiero, R.H. Shoemaker, K.D. Paull, A. Monks, S. Tierney, T.H. Nofziger, M.J. Currens, D. Seniff, and M.R. Boyd Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines Cancer Research 48 1988 4827 4833
30. C.J. Sherr G1 Phase progression: cycling on cue Cell 79 1994 551 555
31. D.E. Shieh, Y.Y. Chen, M.H. Yen, L.C. Chiang, and C.C. Lin Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells Life Science 74 2004 2279 2290
32. N. Stewart, G.G. Hicks, F. Paraskevas, and M. Mowat Evidence for a second cell cycle block at G2/M by p53 Oncogene 10 1995 109 115
33. S.Y. Sun, P. Yue, G.S. Wu, W.S. El-Deiry, B. Shroot, W.K. Hong, and R. Lotan Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells Cancer Research 59 1999 2829 2833
34. Y. Tendler, G. Weisinger, R. Coleman, E. Diamond, S. Lischinsky, H. Kerner, V. Rotter, and O. Zinder Tissue-specific p53 expression in the nervous system. Brain research Molecular Brain Research 72 1999 40 46
35. A. Vidal, and A. Koff Cell-cycle inhibitors: three families united by a common cause Gene 247 2000 1 15
36. C. Wang, and M.S. Kurzer Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells Nutrition and Cancer 28 1997 236 247
37. W. Wang, L. Heideman, C.S. Chung, J.C. Pelling, K.J. Koehler, and D.F. Birt Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines Molecular Carcinogenesis 28 2000 102 110
38. X.M. Yin, Z.N. Oltvai, D.J. Veis-Novack, G.P. Linette, and S.J. Korsmeyer Bcl-2 gene family and the regulation of programmed cell death Cold Spring Harbor Symposia on Quantitative Biology 59 1994 387 393
39. Y. Zhang, N. Fujita, and T. Tsuruo Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis Oncogene 18 1999 1131 1138