메뉴 건너뛰기




Volumn 227, Issue 1, 2012, Pages 81-93

Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris

Author keywords

Cell cell adhesion; Desmosomal cadherin; E cadherin Src signalling; Epithelial cells; Pemphigus vulgaris

Indexed keywords

ACTIN; AUTOANTIGEN; BETA CATENIN; CALCIUM; DESMOGLEIN 3; DETERGENT; GLYCOPROTEIN P; PROTEIN P120; PROTEIN TYROSINE KINASE; UVOMORULIN;

EID: 84862804462     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.3982     Document Type: Article
Times cited : (48)

References (66)
  • 1
    • 35748948971 scopus 로고    scopus 로고
    • ICAM-1-mediated, Src-and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration
    • Allingham MJ, van Buul JD, Burridge K. ICAM-1-mediated, Src-and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. J Immunol 2007; 179: 4053-4064.
    • (2007) J Immunol , vol.179 , pp. 4053-4064
    • Allingham, M.J.1    Van Buul, J.D.2    Burridge, K.3
  • 2
    • 33748893008 scopus 로고    scopus 로고
    • Are desmoglein autoantibodies essential for the immunopathogenesis of pemphigus vulgaris, or just 'witnesses of disease'?
    • Amagai M, Ahmed AR, Kitajima Y, et al. Are desmoglein autoantibodies essential for the immunopathogenesis of pemphigus vulgaris, or just 'witnesses of disease'? Exp Dermatol 2006; 15: 815-831.
    • (2006) Exp Dermatol , vol.15 , pp. 815-831
    • Amagai, M.1    Ahmed, A.R.2    Kitajima, Y.3
  • 3
    • 0025789652 scopus 로고
    • Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion
    • Amagai M, Klaus-Kovtun V, Stanley Jr. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 1991; 67: 869-877.
    • (1991) Cell , vol.67 , pp. 869-877
    • Amagai, M.1    Klaus-Kovtun, V.2    Stanley, Jr.3
  • 4
    • 0029865077 scopus 로고    scopus 로고
    • Pemphigus vulgaris antigen (Desmoglein 3) is localized in the lower epidermis, the site of blister formation in patients
    • Amagai M, Koch PJ, Nishikawa T, et al. Pemphigus vulgaris antigen (desmoglein 3) is localized in the lower epidermis, the site of blister formation in patients. J Invest Dermatol 1996; 106: 351-355. (Pubitemid 26094622)
    • (1996) Journal of Investigative Dermatology , vol.106 , Issue.2 , pp. 351-355
    • Amagai, M.1    Koch, P.J.2    Nishikawa, T.3    Stanley, J.R.4
  • 5
    • 0032900965 scopus 로고    scopus 로고
    • Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3- depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells
    • DOI 10.1046/j.1523-1747.1999.00463.x
    • Aoyama Y, Kitajima Y. Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells. J Invest Dermatol 1999; 112: 67-71. (Pubitemid 29024708)
    • (1999) Journal of Investigative Dermatology , vol.112 , Issue.1 , pp. 67-71
    • Aoyama, Y.1    Kitajima, Y.2
  • 6
    • 0033067371 scopus 로고    scopus 로고
    • A pathogenic autoantibody, pemphigus vulgaris-IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes
    • DOI 10.1002/(SICI)1521-4141(199907)29:07<2233::AID-IMMU2233>3.0. CO;2-4
    • Aoyama Y, Owada MK, Kitajima Y. A pathogenic autoantibody, pemphigus vulgaris-IgG, induces phosphorylation of desmoglein 3, its dissociation from plakoglobin in cultured keratinocytes. Eur J Immunol 1999; 29: 2233-2240. (Pubitemid 29313098)
    • (1999) European Journal of Immunology , vol.29 , Issue.7 , pp. 2233-2240
    • Aoyama, Y.1    Owada, M.K.2    Kitajima, Y.3
  • 8
    • 33748069469 scopus 로고    scopus 로고
    • P38MAPK inhibition prevents disease in pemphigus vulgaris mice
    • Berkowitz P, Hu P, Warren S, et al. p38MAPK inhibition prevents disease in pemphigus vulgaris mice. Proc Natl Acad Sci USA 2006; 103: 12855-12860.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12855-12860
    • Berkowitz, P.1    Hu, P.2    Warren, S.3
  • 13
    • 34250354415 scopus 로고    scopus 로고
    • Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: Characterization of novel signaling pathways downstream of pemphigus vulgaris antigens
    • DOI 10.1074/jbc.M611365200
    • Chernyavsky AI, Arredondo J, Kitajima Y, et al. Desmoglein versus non-desmoglein signaling in pemphigus acantholysis: characterization of novel signaling pathways downstream of pemphigus vulgaris antigens. J Biol Chem 2007; 282: 13804-13812. (Pubitemid 47100562)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.18 , pp. 13804-13812
    • Chernyavsky, A.I.1    Arredondo, J.2    Kitajima, Y.3    Sato-Nagai, M.4    Grando, S.A.5
  • 14
    • 77449142413 scopus 로고    scopus 로고
    • Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell-cell detachment and processing of adhesion molecules via mechanisms that involve PKC
    • Cirillo N, Lanza A, Prime SS. Induction of hyper-adhesion attenuates autoimmune-induced keratinocyte cell-cell detachment and processing of adhesion molecules via mechanisms that involve PKC. Exp Cell Res 2010; 316: 580-592.
    • (2010) Exp Cell Res , vol.316 , pp. 580-592
    • Cirillo, N.1    Lanza, A.2    Prime, S.S.3
  • 15
    • 49649095012 scopus 로고    scopus 로고
    • Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism
    • Delva E, Jennings JM, Calkins CC, et al. Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism. J Biol Chem 2008; 283: 18303-18313.
    • (2008) J Biol Chem , vol.283 , pp. 18303-18313
    • Delva, E.1    Jennings, J.M.2    Calkins, C.C.3
  • 16
    • 0031849706 scopus 로고    scopus 로고
    • The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C
    • DOI 10.1006/excr.1997.3890
    • Denning MF, Guy SG, Ellerbroek SM, et al. The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, protein kinase C. Exp Cell Res 1998; 239: 50-59. (Pubitemid 28368477)
    • (1998) Experimental Cell Research , vol.239 , Issue.1 , pp. 50-59
    • Denning, M.F.1    Guy, S.G.2    Ellerbroek, S.M.3    Norvell, S.M.4    Kowalczyk, A.P.5    Green, K.J.6
  • 17
    • 58349097518 scopus 로고    scopus 로고
    • The ultrastructure of acantholysis in pemphigus vulgaris
    • Diercks GF, Pas HH, Jonkman MF. The ultrastructure of acantholysis in pemphigus vulgaris. Br J Dermatol 2009; 160: 460-461.
    • (2009) Br J Dermatol , vol.160 , pp. 460-461
    • Diercks, G.F.1    Pas, H.H.2    Jonkman, M.F.3
  • 19
    • 0021244964 scopus 로고
    • Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition
    • Fey EG, Wan KM, Penman S. Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition. J Cell Biol 1984; 98: 1973-1984. (Pubitemid 14121828)
    • (1984) Journal of Cell Biology , vol.98 , Issue.6 , pp. 1973-1984
    • Fey, E.G.1    Wan, K.M.2    Penman, S.3
  • 20
    • 33751085125 scopus 로고    scopus 로고
    • Apoptotic mechanism in pemphigus autoimmunoglobulins-induced acantholysis - Possible involvement of the EGF receptor
    • DOI 10.1080/08916930600971836, PII T6462JV5L2N03161, Immunology of Pemphigus and Treatment
    • Frusic-Zlotkin M, Raichenberg D,Wang X, et al. Apoptotic mechanism in pemphigus autoimmunoglobulins-induced acantholysis-possible involvement of the EGF receptor. Autoimmunity 2006; 39: 563-575. (Pubitemid 44768925)
    • (2006) Autoimmunity , vol.39 , Issue.7 , pp. 563-575
    • Frusic-Zlotkin, M.1    Raichenberg, D.2    Wang, X.3    David, M.4    Michel, B.5    Milner, Y.6
  • 21
    • 4944237715 scopus 로고    scopus 로고
    • Cdk5 regulates activation and localization of Src during corneal epithelial wound closure
    • DOI 10.1242/jcs.01271
    • Gao CY, Stepp MA, Fariss R, et al. Cdk5 regulates activation and localization of Src during corneal epithelial wound closure. J Cell Sci 2004; 117: 4089-4098. (Pubitemid 39328297)
    • (2004) Journal of Cell Science , vol.117 , Issue.18 , pp. 4089-4098
    • Gao, C.Y.1    Stepp, M.A.2    Fariss, R.3    Zelenka, P.4
  • 22
    • 77956690137 scopus 로고    scopus 로고
    • Desmosomes in vivo
    • Garrod D. Desmosomes in vivo. Dermatol Res Pract 2010; 2010: 212439.
    • (2010) Dermatol Res Pract , vol.2010 , pp. 212439
    • Garrod, D.1
  • 23
    • 39849097562 scopus 로고    scopus 로고
    • Desmosome structure, composition and function
    • DOI 10.1016/j.bbamem.2007.07.014, PII S0005273607002751
    • Garrod D, Chidgey M. Desmosome structure, composition and function. Biochim Biophys Acta 2008; 1778: 572-587. (Pubitemid 351317796)
    • (2008) Biochimica et Biophysica Acta - Biomembranes , vol.1778 , Issue.3 , pp. 572-587
    • Garrod, D.1    Chidgey, M.2
  • 24
    • 0035991944 scopus 로고    scopus 로고
    • Desmosomal adhesion: Structural basis, molecular mechanism and regulation (review)
    • DOI 10.1080/09687680210132476
    • Garrod DR, Merritt AJ, Nie Z. Desmosomal adhesion: structural basis, molecular mechanism and regulation [review]. Mol Membr Biol 2002; 19: 81-94. (Pubitemid 34753312)
    • (2002) Molecular Membrane Biology , vol.19 , Issue.2 , pp. 81-94
    • Garrod, D.R.1    Merritt, A.J.2    Nie, Z.3
  • 27
    • 0034568948 scopus 로고    scopus 로고
    • Are desmosomes more than tethers for intermediate filaments?
    • Green KJ, Gaudry CA. Are desmosomes more than tethers for intermediate filaments? Nat Rev Mol Cell Biol 2000; 1: 208-216.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 208-216
    • Green, K.J.1    Gaudry, C.A.2
  • 29
    • 0014093660 scopus 로고
    • An electron microscopic study on pemphigus vulgaris of the mouth and the skin with special reference to the intercellular cement
    • Hashimoto K, Lever WF. An electron microscopic study on pemphigus vulgaris of the mouth and the skin with special reference to the intercellular cement. J Invest Dermatol 1967; 48: 540-552.
    • (1967) J Invest Dermatol , vol.48 , pp. 540-552
    • Hashimoto, K.1    Lever, W.F.2
  • 30
    • 0017798491 scopus 로고
    • Epidermal acantholysis induced in vitro by pemphigus autoantibody. An ultrastructural study
    • Hu CH, Michel B, Schiltz Jr. Epidermal acantholysis induced in vitro by pemphigus autoantibody. An ultrastructural study. Am J Pathol 1978; 90: 345-362.
    • (1978) Am J Pathol , vol.90 , pp. 345-362
    • Hu, C.H.1    Michel, B.2    Schiltz, Jr.3
  • 31
    • 0036228744 scopus 로고    scopus 로고
    • Intercellular adhesion, signalling and the cytoskeleton
    • DOI 10.1038/ncb0402-e101
    • Jamora C, Fuchs E. Intercellular adhesion, signalling and the cytoskeleton. Nat Cell Biol 2002; 4: E101-108. (Pubitemid 34308851)
    • (2002) Nature Cell Biology , vol.4 , Issue.4
    • Jamora, C.1    Fuchs, E.2
  • 32
    • 42549173683 scopus 로고    scopus 로고
    • P120-catenin is a novel desmoglein 3 interacting partner: Identification of the p120- Catenin association site of desmoglein 3
    • Kanno M, Isa Y, Aoyama Y, et al. P120-catenin is a novel desmoglein 3 interacting partner: identification of the p120- catenin association site of desmoglein 3. Exp Cell Res 2008; 314: 1683-1692.
    • (2008) Exp Cell Res , vol.314 , pp. 1683-1692
    • Kanno, M.1    Isa, Y.2    Aoyama, Y.3
  • 33
    • 0033584297 scopus 로고    scopus 로고
    • Inhibition of pp60(c-Src) reduces Bcl-X(L) expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors
    • DOI 10.1038/sj.onc.1202835
    • Karni R, Jove R, Levitzki A. Inhibition of pp60c-Src reduces Bcl- XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors. Oncogene 1999; 18: 4654-4662. (Pubitemid 29417740)
    • (1999) Oncogene , vol.18 , Issue.33 , pp. 4654-4662
    • Karni, R.1    Jove, R.2    Levitzki, A.3
  • 34
    • 33751098790 scopus 로고    scopus 로고
    • Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK phosphorylation in human squamous carcinoma cell line
    • DOI 10.1080/08916930600971943, PII U087815760H25855, Immunology of Pemphigus and Treatment
    • Kawasaki Y, Aoyama Y, Tsunoda K, et al. Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK phosphorylation in human squamous carcinoma cell line. Autoimmunity 2006; 39: 587-590. (Pubitemid 44768927)
    • (2006) Autoimmunity , vol.39 , Issue.7 , pp. 587-590
    • Kawasaki, Y.1    Aoyama, Y.2    Tsunoda, K.3    Amagai, M.4    Kitajima, Y.5
  • 35
    • 33947191090 scopus 로고    scopus 로고
    • Calcium-independent desmosomes of keratinocytes are hyper-adhesive
    • DOI 10.1038/sj.jid.5700643, PII 5700643
    • Kimura TE, Merritt AJ, Garrod DR. Calcium-independent desmosomes of keratinocytes are hyper-adhesive. J Invest Dermatol 2007; 127: 775-781. (Pubitemid 46434658)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.4 , pp. 775-781
    • Kimura, T.E.1    Merritt, A.J.2    Garrod, D.R.3
  • 36
    • 0032857374 scopus 로고    scopus 로고
    • Transmembrane signaling for adhesive regulation of desmosomes and hemidesmosomes, for cell-cell datachment induced by pemphigus IgG in cultured keratinocytes: Involvement of protein kinase C
    • Kitajima Y, Aoyama Y, Seishima M. Transmembrane signaling for adhesive regulation of desmosomes and hemidesmosomes, for cell-cell datachment induced by pemphigus IgG in cultured keratinocytes: involvement of protein kinase C. J Invest Dermatol Symp Proc 1999; 4: 137-144.
    • (1999) J Invest Dermatol Symp Proc , vol.4 , pp. 137-144
    • Kitajima, Y.1    Aoyama, Y.2    Seishima, M.3
  • 38
    • 14944369064 scopus 로고    scopus 로고
    • A transient increase in the activity of Src-family kinases induced by cell detachment delays anoikis of intestinal epithelial cells
    • DOI 10.1038/sj.onc.1208379
    • Loza-Coll MA, Perera S, Shi W, et al. A transient increase in the activity of Src-family kinases induced by cell detachment delays anoikis of intestinal epithelial cells. Oncogene 2005; 24: 1727-1737. (Pubitemid 40461129)
    • (2005) Oncogene , vol.24 , Issue.10 , pp. 1727-1737
    • Loza-Coll, M.A.1    Perera, S.2    Shi, W.3    Filmus, J.4
  • 39
    • 79959703249 scopus 로고    scopus 로고
    • RNAi-mediated inhibition of the desmosomal cadherin (desmoglein 3) impairs epithelial cell proliferation
    • Mannan T, Jing S, Foroushania SH, et al. RNAi-mediated inhibition of the desmosomal cadherin (desmoglein 3) impairs epithelial cell proliferation. Cell Prolif 2011; 44: 301-310.
    • (2011) Cell Prolif , vol.44 , pp. 301-310
    • Mannan, T.1    Jing, S.2    Foroushania, S.H.3
  • 41
    • 34249891883 scopus 로고    scopus 로고
    • Not so simple: The complexity of phosphotyrosine signaling at cadherin adhesive contacts
    • DOI 10.1007/s00109-007-0198-x, Special Topic: Tumor Cell Invasion and Metastasis
    • McLachlan RW, Yap AS. Not so simple: the complexity of phosphotyrosine signaling at cadherin adhesive contacts. J Mol Med 2007; 85: 545-554. (Pubitemid 46870898)
    • (2007) Journal of Molecular Medicine , vol.85 , Issue.6 , pp. 545-554
    • McLachlan, R.W.1    Yap, A.S.2
  • 42
    • 39149091017 scopus 로고    scopus 로고
    • Outside-in signaling through integrins and cadherins: A central mechanism to control epidermal growth and differentiation?
    • DOI 10.1038/sj.jid.5701248, PII 5701248
    • Muller EJ, Williamson L, Kolly C, et al. Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation? J Invest Dermatol 2008; 128: 501-516. (Pubitemid 351252683)
    • (2008) Journal of Investigative Dermatology , vol.128 , Issue.3 , pp. 501-516
    • Muller, E.J.1    Williamson, L.2    Kolly, C.3    Suter, M.M.4
  • 43
    • 37249063047 scopus 로고    scopus 로고
    • IgG against extracellular subdomains of desmoglein 3 relates to clinical phenotype of pemphigus vulgaris
    • DOI 10.1111/j.1600-0625.2007.00615.x
    • Muller R, Svoboda V, Wenzel E, et al. IgG against extracellular subdomains of desmoglein 3 relates to clinical phenotype of pemphigus vulgaris. Exp Dermatol 2008; 17: 35-43. (Pubitemid 350269210)
    • (2008) Experimental Dermatology , vol.17 , Issue.1 , pp. 35-43
    • Muller, R.1    Svoboda, V.2    Wenzel, E.3    Muller, H.-H.4    Hertl, M.5
  • 44
    • 0035992434 scopus 로고    scopus 로고
    • Src family kinase inhibitor PP2 restores the E-cadherin/catenin cell adhesion system in human cancer cells and reduces cancer metastasis
    • Nam JS, Ino Y, Sakamoto M, et al. Src family kinase inhibitor PP2 restores the E-cadherin/catenin cell adhesion system in human cancer cells and reduces cancer metastasis. Clin Cancer Res 2002; 8: 2430-2436. (Pubitemid 34753619)
    • (2002) Clinical Cancer Research , vol.8 , Issue.7 , pp. 2430-2436
    • Nam, J.-S.1    Ino, Y.2    Sakamoto, M.3    Hirohashi, S.4
  • 45
    • 0030890618 scopus 로고    scopus 로고
    • Pemphigus IgG activates and translocates protein kinase C from the cytosol to the particulate/cytoskeleton fractions in human keratinocytes
    • Osada K, Seishima M, Kitajima Y. Pemphigus IgG activates and translocates protein kinase C from the cytosol to the particulate/ cytoskeleton fractions in human keratinocytes. J Invest Dermatol 1997; 108: 482-487. (Pubitemid 27148285)
    • (1997) Journal of Investigative Dermatology , vol.108 , Issue.4 , pp. 482-487
    • Osada, K.1    Seishima, M.2    Kitajima, Y.3
  • 46
    • 0038819656 scopus 로고    scopus 로고
    • Contribution of stem cells and differentiated cells to epidermal tumours
    • DOI 10.1038/nrc1096
    • Owens DM, Watt FM. Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer 2003; 3: 444-451. (Pubitemid 37328848)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 444-451
    • Owens, D.M.1    Watt, F.M.2
  • 49
    • 0029019126 scopus 로고
    • Plakoglobin binding by human Dsg3 (pemphigus vulgaris antigen) in keratinocytes requires the cadherin-like intracytoplasmic segment
    • Roh JY, Stanley Jr. Plakoglobin binding by human Dsg3 (pemphigus vulgaris antigen) in keratinocytes requires the cadherin-like intracytoplasmic segment. J Invest Dermatol 1995; 104: 720-724.
    • (1995) J Invest Dermatol , vol.104 , pp. 720-724
    • Roh, J.Y.1    Stanley, Jr.2
  • 51
    • 0033792693 scopus 로고    scopus 로고
    • Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris- IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy
    • Sato M, Aoyama Y, Kitajima Y. Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris- IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy. Lab Invest 2000; 80: 1583-1592.
    • (2000) Lab Invest , vol.80 , pp. 1583-1592
    • Sato, M.1    Aoyama, Y.2    Kitajima, Y.3
  • 52
    • 34548039475 scopus 로고    scopus 로고
    • Beyond steric hindrance: The role of adhesion signaling pathways in the pathogenesis of pemphigus
    • DOI 10.1016/j.jdermsci.2007.05.005, PII S0923181107001739
    • Sharma P, Mao X, Payne AS. Beyond steric hindrance: the role of adhesion signaling pathways in the pathogenesis of pemphigus. J Dermatol Sci 2007; 48: 1-14. (Pubitemid 47284801)
    • (2007) Journal of Dermatological Science , vol.48 , Issue.1 , pp. 1-14
    • Sharma, P.1    Mao, X.2    Payne, A.S.3
  • 56
    • 77955073513 scopus 로고    scopus 로고
    • Desmosomes: Adhesive strength and signalling in health and disease
    • Thomason HA, Scothern A, McHarg S, et al. Desmosomes: adhesive strength and signalling in health and disease. Biochem J 2010; 429: 419-433.
    • (2010) Biochem J , vol.429 , pp. 419-433
    • Thomason, H.A.1    Scothern, A.2    McHarg, S.3
  • 57
    • 78649944079 scopus 로고    scopus 로고
    • Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src
    • Tsang SM, Liu L, Teh MT, et al. Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src. PLoS One 2010; 5: e14211.
    • (2010) PLoS One , vol.5
    • Tsang, S.M.1    Liu, L.2    Teh, M.T.3
  • 58
    • 0034695656 scopus 로고    scopus 로고
    • Directed actin polymerization is the driving force for epithelial cell- cell adhesion
    • Vasioukhin V, Bauer C, Yin M, et al. Directed actin polymerization is the driving force for epithelial cell-cell adhesion. Cell 2000; 100: 209-219. (Pubitemid 30064909)
    • (2000) Cell , vol.100 , Issue.2 , pp. 209-219
    • Vasioukhin, V.1    Bauer, C.2    Yin, M.3    Fuchs, E.4
  • 59
    • 34250172068 scopus 로고    scopus 로고
    • Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference
    • DOI 10.1016/j.yexcr.2007.01.010, PII S0014482707000249
    • Wan H, South AP, Hart IR. Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference. Exp Cell Res 2007; 313: 2336-2344. (Pubitemid 46900938)
    • (2007) Experimental Cell Research , vol.313 , Issue.11 , pp. 2336-2344
    • Wan, H.1    South, A.P.2    Hart, I.R.3
  • 62
    • 0001305901 scopus 로고
    • An electron microscopic study of acantholysis in pemphigus vulgaris
    • Wilgram GF, Caulfield JB, Lever WF. An electron microscopic study of acantholysis in pemphigus vulgaris. J Invest Dermatol 1961; 36: 373-382.
    • (1961) J Invest Dermatol , vol.36 , pp. 373-382
    • Wilgram, G.F.1    Caulfield, J.B.2    Lever, W.F.3
  • 64
    • 28844473269 scopus 로고    scopus 로고
    • Mechanisms of plakoglobin-dependent adhesion: Desmosome-specific functions in assembly and regulation by epidermal growth factor receptor
    • DOI 10.1074/jbc.M506692200
    • Yin T, Getsios S, Caldelari R, et al. Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor. J Biol Chem 2005; 280: 40355-40363. (Pubitemid 41779173)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.48 , pp. 40355-40363
    • Yin, T.1    Getsios, S.2    Caldelari, R.3    Godsel, L.M.4    Kowalczyk, A.P.5    Muller, E.J.6    Green, K.J.7
  • 65
    • 9244238200 scopus 로고    scopus 로고
    • Regulation of desmosome assembly and adhesion
    • DOI 10.1016/j.semcdb.2004.09.005, PII S1084952104000916
    • Yin T, Green KJ. Regulation of desmosome assembly and adhesion. Semin Cell Dev Biol 2004; 15: 665-677. (Pubitemid 39550246)
    • (2004) Seminars in Cell and Developmental Biology , vol.15 , Issue.6 SPEC. ISS. , pp. 665-677
    • Yin, T.1    Green, K.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.