메뉴 건너뛰기




Volumn 313, Issue 11, 2007, Pages 2336-2344

Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference

Author keywords

Desmoplakin; Desmosomes; Keratinocyte; Proliferation; RNAi

Indexed keywords

DESMOPLAKIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

EID: 34250172068     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.01.010     Document Type: Article
Times cited : (36)

References (44)
  • 1
    • 1842733459 scopus 로고    scopus 로고
    • Working out the strength and flexibility of desmosomes
    • Getsios S., Huen A.C., and Green K.J. Working out the strength and flexibility of desmosomes. Nat. Rev., Mol. Cell Biol. 5 (2004) 271-281
    • (2004) Nat. Rev., Mol. Cell Biol. , vol.5 , pp. 271-281
    • Getsios, S.1    Huen, A.C.2    Green, K.J.3
  • 2
    • 0035991944 scopus 로고    scopus 로고
    • Desmosomal adhesion: structural basis, molecular mechanism and regulation
    • (Review)
    • Garrod D.R., Merritt A.J., and Nie Z. Desmosomal adhesion: structural basis, molecular mechanism and regulation. (Review). Mol. Membr. Biol. 19 (2002) 81-94
    • (2002) Mol. Membr. Biol. , vol.19 , pp. 81-94
    • Garrod, D.R.1    Merritt, A.J.2    Nie, Z.3
  • 4
    • 0037459077 scopus 로고    scopus 로고
    • Sticky business: orchestrating cellular signals at adherens junctions
    • Perez-Moreno M., Jamora C., and Fuchs E. Sticky business: orchestrating cellular signals at adherens junctions. Cell 112 (2003) 535-548
    • (2003) Cell , vol.112 , pp. 535-548
    • Perez-Moreno, M.1    Jamora, C.2    Fuchs, E.3
  • 5
    • 0029895526 scopus 로고    scopus 로고
    • Mice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation, and epidermal differentiation
    • Allen E., Yu Q.C., and Fuchs E. Mice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation, and epidermal differentiation. J. Cell Biol. 133 (1996) 1367-1382
    • (1996) J. Cell Biol. , vol.133 , pp. 1367-1382
    • Allen, E.1    Yu, Q.C.2    Fuchs, E.3
  • 6
    • 0036315292 scopus 로고    scopus 로고
    • Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation
    • Merritt A.J., Berika M.Y., Zhai W., Kirk S.E., Ji B., Hardman M.J., and Garrod D.R. Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation. Mol. Cell. Biol. 22 (2002) 5846-5858
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5846-5858
    • Merritt, A.J.1    Berika, M.Y.2    Zhai, W.3    Kirk, S.E.4    Ji, B.5    Hardman, M.J.6    Garrod, D.R.7
  • 7
    • 4344680669 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells
    • Lorch J.H., Klessner J., Park J.K., Getsios S., Wu Y.L., Stack M.S., and Green K.J. Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells. J. Biol. Chem. 279 (2004) 37191-37200
    • (2004) J. Biol. Chem. , vol.279 , pp. 37191-37200
    • Lorch, J.H.1    Klessner, J.2    Park, J.K.3    Getsios, S.4    Wu, Y.L.5    Stack, M.S.6    Green, K.J.7
  • 9
    • 0029847068 scopus 로고    scopus 로고
    • Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly
    • Bornslaeger E.A., Corcoran C.M., Stappenbeck T.S., and Green K.J. Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly. J. Cell Biol. 134 (1996) 985-1001
    • (1996) J. Cell Biol. , vol.134 , pp. 985-1001
    • Bornslaeger, E.A.1    Corcoran, C.M.2    Stappenbeck, T.S.3    Green, K.J.4
  • 14
    • 20644437528 scopus 로고    scopus 로고
    • Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage
    • Gallicano G.I., Kouklis P., Bauer C., Yin M., Vasioukhin V., Degenstein L., and Fuchs E. Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage. J. Cell Biol. 143 (1998) 2009-2022
    • (1998) J. Cell Biol. , vol.143 , pp. 2009-2022
    • Gallicano, G.I.1    Kouklis, P.2    Bauer, C.3    Yin, M.4    Vasioukhin, V.5    Degenstein, L.6    Fuchs, E.7
  • 15
    • 0035066688 scopus 로고    scopus 로고
    • Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature
    • Gallicano G.I., Bauer C., and Fuchs E. Rescuing desmoplakin function in extra-embryonic ectoderm reveals the importance of this protein in embryonic heart, neuroepithelium, skin and vasculature. Development 128 (2001) 929-941
    • (2001) Development , vol.128 , pp. 929-941
    • Gallicano, G.I.1    Bauer, C.2    Fuchs, E.3
  • 19
    • 0242351028 scopus 로고    scopus 로고
    • Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes
    • Wan H., Stone M.G., Simpson C., Reynolds L.E., Marshall J.F., Hart I.R., Hodivala-Dilke K.M., and Eady R.A. Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes. J. Cell Sci. 116 (2003) 4239-4248
    • (2003) J. Cell Sci. , vol.116 , pp. 4239-4248
    • Wan, H.1    Stone, M.G.2    Simpson, C.3    Reynolds, L.E.4    Marshall, J.F.5    Hart, I.R.6    Hodivala-Dilke, K.M.7    Eady, R.A.8
  • 20
    • 0031849706 scopus 로고    scopus 로고
    • The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C
    • Denning M.F., Guy S.G., Ellerbroek S.M., Norvell S.M., Kowalczyk A.P., and Green K.J. The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C. Exp. Cell Res. 239 (1998) 50-59
    • (1998) Exp. Cell Res. , vol.239 , pp. 50-59
    • Denning, M.F.1    Guy, S.G.2    Ellerbroek, S.M.3    Norvell, S.M.4    Kowalczyk, A.P.5    Green, K.J.6
  • 21
    • 0033017076 scopus 로고    scopus 로고
    • Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts
    • Schoop V.M., Mirancea N., and Fusenig N.E. Epidermal organization and differentiation of HaCaT keratinocytes in organotypic coculture with human dermal fibroblasts. J. Invest. Dermatol. 112 (1999) 343-353
    • (1999) J. Invest. Dermatol. , vol.112 , pp. 343-353
    • Schoop, V.M.1    Mirancea, N.2    Fusenig, N.E.3
  • 22
    • 1042291164 scopus 로고    scopus 로고
    • Down-regulation of MEK/ERK signaling by E-cadherin-dependent PI3K/Akt pathway in differentiating intestinal epithelial cells
    • Laprise P., Langlois M.J., Boucher M.J., Jobin C., and Rivard N. Down-regulation of MEK/ERK signaling by E-cadherin-dependent PI3K/Akt pathway in differentiating intestinal epithelial cells. J. Cell Physiol. 199 (2004) 32-39
    • (2004) J. Cell Physiol. , vol.199 , pp. 32-39
    • Laprise, P.1    Langlois, M.J.2    Boucher, M.J.3    Jobin, C.4    Rivard, N.5
  • 25
    • 17444398948 scopus 로고    scopus 로고
    • Molecular abnormalities of the desmosomal protein desmoplakin in human disease
    • Lai Cheong J.E., Wessagowit V., and McGrath J.A. Molecular abnormalities of the desmosomal protein desmoplakin in human disease. Clin. Exp. Dermatol. 30 (2005) 261-266
    • (2005) Clin. Exp. Dermatol. , vol.30 , pp. 261-266
    • Lai Cheong, J.E.1    Wessagowit, V.2    McGrath, J.A.3
  • 26
    • 0035723758 scopus 로고    scopus 로고
    • Central role of the plakoglobin-binding domain for desmoglein 3 incorporation into desmosomes
    • Andl C.D., and Stanley J.R. Central role of the plakoglobin-binding domain for desmoglein 3 incorporation into desmosomes. J. Invest. Dermatol. 117 (2001) 1068-1074
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 1068-1074
    • Andl, C.D.1    Stanley, J.R.2
  • 27
    • 0029019126 scopus 로고
    • Plakoglobin binding by human Dsg3 (pemphigus vulgaris antigen) in keratinocytes requires the cadherin-like intracytoplasmic segment
    • Roh J.Y., and Stanley J.R. Plakoglobin binding by human Dsg3 (pemphigus vulgaris antigen) in keratinocytes requires the cadherin-like intracytoplasmic segment. J. Invest. Dermatol. 104 (1995) 720-724
    • (1995) J. Invest. Dermatol. , vol.104 , pp. 720-724
    • Roh, J.Y.1    Stanley, J.R.2
  • 28
    • 0027942767 scopus 로고
    • Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability
    • Kowalczyk A.P., Palka H.L., Luu H.H., Nilles L.A., Anderson J.E., Wheelock M.J., and Green K.J. Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability. J. Biol. Chem. 269 (1994) 31214-31223
    • (1994) J. Biol. Chem. , vol.269 , pp. 31214-31223
    • Kowalczyk, A.P.1    Palka, H.L.2    Luu, H.H.3    Nilles, L.A.4    Anderson, J.E.5    Wheelock, M.J.6    Green, K.J.7
  • 30
    • 0034695656 scopus 로고    scopus 로고
    • Directed actin polymerization is the driving force for epithelial cell-cell adhesion
    • Vasioukhin V., Bauer C., Yin M., and Fuchs E. Directed actin polymerization is the driving force for epithelial cell-cell adhesion. Cell 100 (2000) 209-219
    • (2000) Cell , vol.100 , pp. 209-219
    • Vasioukhin, V.1    Bauer, C.2    Yin, M.3    Fuchs, E.4
  • 31
    • 9244238200 scopus 로고    scopus 로고
    • Regulation of desmosome assembly and adhesion
    • Yin T., and Green K.J. Regulation of desmosome assembly and adhesion. Semin. Cell Dev. Biol. 15 (2004) 665-677
    • (2004) Semin. Cell Dev. Biol. , vol.15 , pp. 665-677
    • Yin, T.1    Green, K.J.2
  • 33
    • 0034020357 scopus 로고    scopus 로고
    • The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells
    • Wallis S., Lloyd S., Wise I., Ireland G., Fleming T.P., and Garrod D. The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cells. Mol. Biol. Cell 11 (2000) 1077-1092
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1077-1092
    • Wallis, S.1    Lloyd, S.2    Wise, I.3    Ireland, G.4    Fleming, T.P.5    Garrod, D.6
  • 34
    • 0029824402 scopus 로고    scopus 로고
    • Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: an immunohistochemical aid to diagnosis
    • (published erratum appears in Acta Derm Venereol 1996 Nov;76(6):504)
    • Krunic A.L., Garrod D.R., Smith N.P., Orchard G.S., and Cvijetic O.B. Differential expression of desmosomal glycoproteins in keratoacanthoma and squamous cell carcinoma of the skin: an immunohistochemical aid to diagnosis. (published erratum appears in Acta Derm Venereol 1996 Nov;76(6):504). Acta Derm. -Venereol. 76 (1996) 394-398
    • (1996) Acta Derm. -Venereol. , vol.76 , pp. 394-398
    • Krunic, A.L.1    Garrod, D.R.2    Smith, N.P.3    Orchard, G.S.4    Cvijetic, O.B.5
  • 35
    • 0031888858 scopus 로고    scopus 로고
    • Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin
    • Krunic A.L., Garrod D.R., Madani S., Buchanan M.D., and Clark R.E. Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin. Br. J. Cancer 77 (1998) 1275-1279
    • (1998) Br. J. Cancer , vol.77 , pp. 1275-1279
    • Krunic, A.L.1    Garrod, D.R.2    Madani, S.3    Buchanan, M.D.4    Clark, R.E.5
  • 36
    • 0242708723 scopus 로고    scopus 로고
    • Expression of desmosomal proteins in squamous cell carcinomas of the skin
    • Kurzen H., Munzing I., and Hartschuh W. Expression of desmosomal proteins in squamous cell carcinomas of the skin. J. Cutan. Pathol. 30 (2003) 621-630
    • (2003) J. Cutan. Pathol. , vol.30 , pp. 621-630
    • Kurzen, H.1    Munzing, I.2    Hartschuh, W.3
  • 40
    • 1842857530 scopus 로고    scopus 로고
    • Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells
    • Eshkind L., Tian Q., Schmidt A., Franke W.W., Windoffer R., and Leube R.E. Loss of desmoglein 2 suggests essential functions for early embryonic development and proliferation of embryonal stem cells. Eur. J. Cell Biol. 81 (2002) 592-598
    • (2002) Eur. J. Cell Biol. , vol.81 , pp. 592-598
    • Eshkind, L.1    Tian, Q.2    Schmidt, A.3    Franke, W.W.4    Windoffer, R.5    Leube, R.E.6
  • 41
    • 0036228744 scopus 로고    scopus 로고
    • Intercellular adhesion, signalling and the cytoskeleton
    • Jamora C., and Fuchs E. Intercellular adhesion, signalling and the cytoskeleton. Nat. Cell Biol. 4 (2002) E101-E108
    • (2002) Nat. Cell Biol. , vol.4
    • Jamora, C.1    Fuchs, E.2
  • 42
    • 18244385986 scopus 로고    scopus 로고
    • Proliferation, cell cycle exit, and onset of terminal differentiation in cultured keratinocytes: pre-programmed pathways in control of C-Myc and Notch1 prevail over extracellular calcium signals
    • Kolly C., Suter M.M., and Muller E.J. Proliferation, cell cycle exit, and onset of terminal differentiation in cultured keratinocytes: pre-programmed pathways in control of C-Myc and Notch1 prevail over extracellular calcium signals. J. Invest. Dermatol. 124 (2005) 1014-1025
    • (2005) J. Invest. Dermatol. , vol.124 , pp. 1014-1025
    • Kolly, C.1    Suter, M.M.2    Muller, E.J.3
  • 43
    • 0033516481 scopus 로고    scopus 로고
    • Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex
    • Pece S., Chiariello M., Murga C., and Gutkind J.S. Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex. J. Biol. Chem. 274 (1999) 19347-19351
    • (1999) J. Biol. Chem. , vol.274 , pp. 19347-19351
    • Pece, S.1    Chiariello, M.2    Murga, C.3    Gutkind, J.S.4
  • 44
    • 0034731148 scopus 로고    scopus 로고
    • Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation
    • Pece S., and Gutkind J.S. Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation. J. Biol. Chem. 275 (2000) 41227-41233
    • (2000) J. Biol. Chem. , vol.275 , pp. 41227-41233
    • Pece, S.1    Gutkind, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.