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Volumn 25, Issue 14, 2006, Pages 3298-3309

Pemphigus vulgaris identifies plakoglobin as key suppressor of c-Myc in the skin

Author keywords

catenin; Desmosomes; Epidermis; Plakoglobin; Stem cells

Indexed keywords

BETA CATENIN; PLAKOGLOBIN; RNA;

EID: 33746494904     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601224     Document Type: Article
Times cited : (160)

References (55)
  • 1
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H, Bauer A, Stappert J, Kispert A, Kemler R (1997) Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J 16: 3797-3804
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 3
    • 0028104313 scopus 로고
    • 'Eczema' revisited. A status report based upon current textbooks of dermatology
    • Altekrueger I, Ackerman AB (1994) 'Eczema' revisited. A status report based upon current textbooks of dermatology. Am J Dermatopathol 16: 517-522; discussion 523-531
    • (1994) Am J Dermatopathol , vol.16 , pp. 517-522
    • Altekrueger, I.1    Ackerman, A.B.2
  • 4
    • 0025789652 scopus 로고
    • Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion
    • Amagai M, Klaus-Kovtun V, Stanley JR (1991) Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 67: 869-877
    • (1991) Cell , vol.67 , pp. 869-877
    • Amagai, M.1    Klaus-Kovtun, V.2    Stanley, J.R.3
  • 5
    • 0035069781 scopus 로고    scopus 로고
    • Keratinocyte growth factor induces hyperproliferation and delays differentiation in a skin equivalent model system
    • Andreadis ST, Hamoen KE, Yarmush ML, Morgan JR (2001) Keratinocyte growth factor induces hyperproliferation and delays differentiation in a skin equivalent model system. FASEB J 15: 898-906
    • (2001) FASEB J , vol.15 , pp. 898-906
    • Andreadis, S.T.1    Hamoen, K.E.2    Yarmush, M.L.3    Morgan, J.R.4
  • 6
    • 0020030480 scopus 로고
    • Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease
    • Anhalt GJ, Labib RS, Voorhees JJ, Beals TF, Diaz LA (1982) Induction of pemphigus in neonatal mice by passive transfer of IgG from patients with the disease. N Engl J Med 306: 1189-1196
    • (1982) N Engl J Med , vol.306 , pp. 1189-1196
    • Anhalt, G.J.1    Labib, R.S.2    Voorhees, J.J.3    Beals, T.F.4    Diaz, L.A.5
  • 7
    • 0032900965 scopus 로고    scopus 로고
    • Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells
    • Aoyama Y, Kitajima Y (1999) Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells. J Invest Dermatol 112: 67-71
    • (1999) J Invest Dermatol , vol.112 , pp. 67-71
    • Aoyama, Y.1    Kitajima, Y.2
  • 8
    • 0035901594 scopus 로고    scopus 로고
    • c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
    • Arnold I, Watt FM (2001) c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 11: 558-568
    • (2001) Curr Biol , vol.11 , pp. 558-568
    • Arnold, I.1    Watt, F.M.2
  • 10
    • 23244452354 scopus 로고    scopus 로고
    • Stem cell depletion through epidermal deletion of Rac1
    • Benitah SA, Frye M, Glogauer M, Watt FM (2005) Stem cell depletion through epidermal deletion of Rac1. Science 309: 933-935
    • (2005) Science , vol.309 , pp. 933-935
    • Benitah, S.A.1    Frye, M.2    Glogauer, M.3    Watt, F.M.4
  • 11
    • 76549160299 scopus 로고
    • Demonstration of skin autoantibodies in sera of pemphigus vulgaris patients by indirect immunofluorescence staining
    • Beutner EH, Jordon RE (1964) Demonstration of skin autoantibodies in sera of pemphigus vulgaris patients by indirect immunofluorescence staining. Proc Soc Exp Biol Med 117: 505-510
    • (1964) Proc Soc Exp Biol Med , vol.117 , pp. 505-510
    • Beutner, E.H.1    Jordon, R.E.2
  • 12
    • 25444466556 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death
    • Calautti E, Li J, Saoncella S, Brissette JL, Goetinck PF (2005) Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death. J Biol Chem 280: 32856-32865
    • (2005) J Biol Chem , vol.280 , pp. 32856-32865
    • Calautti, E.1    Li, J.2    Saoncella, S.3    Brissette, J.L.4    Goetinck, P.F.5
  • 15
    • 16844364151 scopus 로고    scopus 로고
    • LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
    • Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S (2005) LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 132: 885-896
    • (2005) Development , vol.132 , pp. 885-896
    • Cartwright, P.1    McLean, C.2    Sheppard, A.3    Rivett, D.4    Jones, K.5    Dalton, S.6
  • 16
    • 0034678347 scopus 로고    scopus 로고
    • Plakoglobin suppresses epithelial proliferation and hair growth in vivo
    • Charpentier E, Lavker RM, Acquista E, Cowin P (2000) Plakoglobin suppresses epithelial proliferation and hair growth in vivo. J Cell Biol 149: 503-520
    • (2000) J Cell Biol , vol.149 , pp. 503-520
    • Charpentier, E.1    Lavker, R.M.2    Acquista, E.3    Cowin, P.4
  • 18
    • 0036120562 scopus 로고    scopus 로고
    • The cadherin-catenin adhesion system in signaling and cancer
    • Conacci-Sorrell M, Zhurinsky J, Ben-Ze'ev A (2002) The cadherin-catenin adhesion system in signaling and cancer. J Clin Invest 109: 987-991
    • (2002) J Clin Invest , vol.109 , pp. 987-991
    • Conacci-Sorrell, M.1    Zhurinsky, J.2    Ben-Ze'ev, A.3
  • 19
    • 0029849450 scopus 로고    scopus 로고
    • Role of mitochondria in tributyltin-induced interleukin-1alpha production in murine keratinocytes
    • Corsini E, Schubert C, Marinovich M, Galli CL (1996) Role of mitochondria in tributyltin-induced interleukin-1alpha production in murine keratinocytes. J Invest Dermatol 107: 720-725
    • (1996) J Invest Dermatol , vol.107 , pp. 720-725
    • Corsini, E.1    Schubert, C.2    Marinovich, M.3    Galli, C.L.4
  • 20
    • 0035881472 scopus 로고    scopus 로고
    • Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation
    • Frank SR, Schroeder M, Fernandez P, Taubert S, Amati B (2001) Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev 15: 2069-2082
    • (2001) Genes Dev , vol.15 , pp. 2069-2082
    • Frank, S.R.1    Schroeder, M.2    Fernandez, P.3    Taubert, S.4    Amati, B.5
  • 21
    • 0042913170 scopus 로고    scopus 로고
    • Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
    • Frye M, Gardner C, Li ER, Arnold I, Watt FM (2003) Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development 130: 2793-2808
    • (2003) Development , vol.130 , pp. 2793-2808
    • Frye, M.1    Gardner, C.2    Li, E.R.3    Arnold, I.4    Watt, F.M.5
  • 22
    • 30044444270 scopus 로고    scopus 로고
    • Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway
    • Fukuyama T, Ogita H, Kawakatsu T, Inagaki M, Takai Y (2006) Activation of Rac by cadherin through the c-Src-Rap1-phosphatidylinositol 3-kinase-Vav2 pathway. Oncogene 25: 8-19
    • (2006) Oncogene , vol.25 , pp. 8-19
    • Fukuyama, T.1    Ogita, H.2    Kawakatsu, T.3    Inagaki, M.4    Takai, Y.5
  • 23
    • 0030778620 scopus 로고    scopus 로고
    • c-Myc promotes differentiation of human epidermal stem cells
    • Gandarillas A, Watt FM (1997) c-Myc promotes differentiation of human epidermal stem cells. Genes Dev 11: 2869-2882
    • (1997) Genes Dev , vol.11 , pp. 2869-2882
    • Gandarillas, A.1    Watt, F.M.2
  • 24
    • 0033580842 scopus 로고    scopus 로고
    • Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro
    • Hecht A, Litterst CM, Huber O, Kemler R (1999) Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro. J Biol Chem 274: 18017-18025
    • (1999) J Biol Chem , vol.274 , pp. 18017-18025
    • Hecht, A.1    Litterst, C.M.2    Huber, O.3    Kemler, R.4
  • 25
    • 0345343608 scopus 로고    scopus 로고
    • Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
    • Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG, Kemler R (1996) Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech Dev 59: 3-10
    • (1996) Mech Dev , vol.59 , pp. 3-10
    • Huber, O.1    Korn, R.2    McLaughlin, J.3    Ohsugi, M.4    Herrmann, B.G.5    Kemler, R.6
  • 27
    • 0033600749 scopus 로고    scopus 로고
    • Axin directly interacts with plakoglobin and regulates its stability
    • Kodama S, Ikeda S, Asahara T, Kishida M, Kikuchi A (1999) Axin directly interacts with plakoglobin and regulates its stability. J Biol Chem 274: 27682-27688
    • (1999) J Biol Chem , vol.274 , pp. 27682-27688
    • Kodama, S.1    Ikeda, S.2    Asahara, T.3    Kishida, M.4    Kikuchi, A.5
  • 28
    • 0034212818 scopus 로고    scopus 로고
    • Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin
    • Kolligs FT, Kolligs B, Hajra KM, Hu G, Tani M, Cho KR, Fearon ER (2000) Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev 14: 1319-1331
    • (2000) Genes Dev , vol.14 , pp. 1319-1331
    • Kolligs, F.T.1    Kolligs, B.2    Hajra, K.M.3    Hu, G.4    Tani, M.5    Cho, K.R.6    Fearon, E.R.7
  • 29
    • 18244385986 scopus 로고    scopus 로고
    • Proliferation, cell cycle exit, and onset of terminal differentiation in cultured keratinocytes: Pre-programmed pathways in control of C-Myc and Notch1 prevail over extracellular calcium signals
    • Kolly C, Suter MM, Muller EJ (2005) Proliferation, cell cycle exit, and onset of terminal differentiation in cultured keratinocytes: pre-programmed pathways in control of C-Myc and Notch1 prevail over extracellular calcium signals. J Invest Dermatol 124: 1014-1025
    • (2005) J Invest Dermatol , vol.124 , pp. 1014-1025
    • Kolly, C.1    Suter, M.M.2    Muller, E.J.3
  • 30
    • 0033557198 scopus 로고    scopus 로고
    • Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceous and vulgaris
    • Mahoney MG, Wang Z, Rothenberger K, Koch PJ, Amagai M, Stanley JR (1999) Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceous and vulgaris. J Clin Invest 103: 461-468
    • (1999) J Clin Invest , vol.103 , pp. 461-468
    • Mahoney, M.G.1    Wang, Z.2    Rothenberger, K.3    Koch, P.J.4    Amagai, M.5    Stanley, J.R.6
  • 31
    • 0029658030 scopus 로고    scopus 로고
    • The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression
    • Missero C, Di Cunto F, Kiyokawa H, Koff A, Dotto GP (1996) The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. Genes Dev 10: 3065-3075
    • (1996) Genes Dev , vol.10 , pp. 3065-3075
    • Missero, C.1    Di Cunto, F.2    Kiyokawa, H.3    Koff, A.4    Dotto, G.P.5
  • 34
    • 0036023356 scopus 로고    scopus 로고
    • Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
    • Niemann C, Owens DM, Hulsken J, Birchmeier W, Watt FM (2002) Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development 129: 95-109
    • (2002) Development , vol.129 , pp. 95-109
    • Niemann, C.1    Owens, D.M.2    Hulsken, J.3    Birchmeier, W.4    Watt, F.M.5
  • 35
    • 0038819656 scopus 로고    scopus 로고
    • Contribution of stem cells and differentiated cells to epidermal tumours
    • Owens DM, Watt FM (2003) Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer 3: 444-451
    • (2003) Nat Rev Cancer , vol.3 , pp. 444-451
    • Owens, D.M.1    Watt, F.M.2
  • 37
    • 0033001621 scopus 로고    scopus 로고
    • Reversible activation of c-Myc in skin: Induction of a complex neoplastic phenotype by a single oncogenic lesion
    • Pelengaris S, Littlewood T, Khan M, Elia G, Evan G (1999) Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Mol Cell 3: 565-577
    • (1999) Mol Cell , vol.3 , pp. 565-577
    • Pelengaris, S.1    Littlewood, T.2    Khan, M.3    Elia, G.4    Evan, G.5
  • 39
    • 0033792693 scopus 로고    scopus 로고
    • Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy
    • Sato M, Aoyama Y, Kitajima Y (2000) Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy. Lab Invest 80: 1583-1592
    • (2000) Lab Invest , vol.80 , pp. 1583-1592
    • Sato, M.1    Aoyama, Y.2    Kitajima, Y.3
  • 40
    • 0031934294 scopus 로고    scopus 로고
    • Lack of mucosal involvement in pemphigus foliaceous may be due to low expression of desmoglein 1
    • Shirakata Y, Amagai M, Hanakawa Y, Nishikawa T, Hashimoto K (1998) Lack of mucosal involvement in pemphigus foliaceous may be due to low expression of desmoglein 1. J Invest Dermatol 110: 76-78
    • (1998) J Invest Dermatol , vol.110 , pp. 76-78
    • Shirakata, Y.1    Amagai, M.2    Hanakawa, Y.3    Nishikawa, T.4    Hashimoto, K.5
  • 42
    • 0036713995 scopus 로고    scopus 로고
    • Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents
    • Tao L, Kramer PM, Wang W, Yang S, Lubet RA, Steele VE, Pereira MA (2002) Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents. Carcinogenesis 23: 1447-1454
    • (2002) Carcinogenesis , vol.23 , pp. 1447-1454
    • Tao, L.1    Kramer, P.M.2    Wang, W.3    Yang, S.4    Lubet, R.A.5    Steele, V.E.6    Pereira, M.A.7
  • 43
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F (1999) Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 45
    • 0025794148 scopus 로고
    • LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function
    • corrected [published erratum appears in Genes Dev 1991 Jun; 5(6):following 1113]
    • Travis A, Amsterdam A, Belanger C, Grosschedl R (1991) LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected] [published erratum appears in Genes Dev 1991 Jun; 5(6):following 1113]. Genes Dev 5: 880-894
    • (1991) Genes Dev , vol.5 , pp. 880-894
    • Travis, A.1    Amsterdam, A.2    Belanger, C.3    Grosschedl, R.4
  • 46
    • 0037442123 scopus 로고    scopus 로고
    • Induction of pemphigus phenotype by a mouse monoclonal antibody against the aminoterminal adhesive interface of desmoglein 3
    • Tsunoda K, Ota T, Aoki M, Yamada T, Nagai T, Nakagawa T, Koyasu S, Nishikawa T, Amagai M (2003) Induction of pemphigus phenotype by a mouse monoclonal antibody against the aminoterminal adhesive interface of desmoglein 3. J Immunol 170: 2170-2178
    • (2003) J Immunol , vol.170 , pp. 2170-2178
    • Tsunoda, K.1    Ota, T.2    Aoki, M.3    Yamada, T.4    Nagai, T.5    Nakagawa, T.6    Koyasu, S.7    Nishikawa, T.8    Amagai, M.9
  • 48
    • 0033607029 scopus 로고    scopus 로고
    • Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis
    • Waikel RL, Wang XJ, Roop DR (1999) Targeted expression of c-Myc in the epidermis alters normal proliferation, differentiation and UV-B induced apoptosis. Oncogene 18: 4870-4878
    • (1999) Oncogene , vol.18 , pp. 4870-4878
    • Waikel, R.L.1    Wang, X.J.2    Roop, D.R.3
  • 49
    • 0242351028 scopus 로고    scopus 로고
    • Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes
    • Wan H, Stone MG, Simpson C, Reynolds LE, Marshall JF, Hart IR, Hodivala-Dilke KM, Eady RA (2003) Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes. J Cell Sci 116: 4239-4248
    • (2003) J Cell Sci , vol.116 , pp. 4239-4248
    • Wan, H.1    Stone, M.G.2    Simpson, C.3    Reynolds, L.E.4    Marshall, J.F.5    Hart, I.R.6    Hodivala-Dilke, K.M.7    Eady, R.A.8
  • 50
    • 0035427373 scopus 로고    scopus 로고
    • Stem cell fate and patterning in mammalian epidermis
    • Watt FM (2001) Stem cell fate and patterning in mammalian epidermis. Curr Opin Genet Dev 11: 410-417
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 410-417
    • Watt, F.M.1
  • 51
    • 28844473269 scopus 로고    scopus 로고
    • Mechanisms of Plakoglobin-dependent adhesion: Desmosome-specific functions in assembly and regulation by epidermal growth factor receptor
    • Yin T, Getsios S, Caldelari R, Godsel LM, Kowalczyk AP, Muller EJ, Green KJ (2005a) Mechanisms of Plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor. J Biol Chem 280: 40355-40363
    • (2005) J Biol Chem , vol.280 , pp. 40355-40363
    • Yin, T.1    Getsios, S.2    Caldelari, R.3    Godsel, L.M.4    Kowalczyk, A.P.5    Muller, E.J.6    Green, K.J.7
  • 53
    • 0142057146 scopus 로고    scopus 로고
    • Low molecular weight inhibitors of Myc-Max interaction and function
    • Yin X, Giap C, Lazo JS, Prochownik EV (2003) Low molecular weight inhibitors of Myc-Max interaction and function. Oncogene 22: 6151-6159
    • (2003) Oncogene , vol.22 , pp. 6151-6159
    • Yin, X.1    Giap, C.2    Lazo, J.S.3    Prochownik, E.V.4
  • 54
    • 0033788835 scopus 로고    scopus 로고
    • Plakoglobin and β-catenin: Protein interactions, regulation and biological roles
    • Zhurinsky J, Shtutman M, Ben-Ze'ev A (2000a) Plakoglobin and β-catenin: protein interactions, regulation and biological roles. J Cell Sci 113 (Part 18): 3127-3139
    • (2000) J Cell Sci , vol.113 , Issue.18 PART , pp. 3127-3139
    • Zhurinsky, J.1    Shtutman, M.2    Ben-Ze'ev, A.3
  • 55
    • 0034036739 scopus 로고    scopus 로고
    • Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin
    • Zhurinsky J, Shtutman M, Ben-Ze'ev A (2000b) Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin. Mol Cell Biol 20: 4238-4252
    • (2000) Mol Cell Biol , vol.20 , pp. 4238-4252
    • Zhurinsky, J.1    Shtutman, M.2    Ben-Ze'ev, A.3


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