Actin at cell-cell junctions is composed of two dynamic and functional populations

Journal of Cell Science

Volumn 118, Issue 23, 2005, Pages 5549-5562

  Zhang, Juankun ^a   Betson, Martha ^a,d   Erasmus, Jennifer ^a   Zeikos, Kostas ^a   Bailly, Maryse ^b   Cramer, Louise P ^c   Braga, Vania M M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Actin bundles; Cadherins; Cell cell contact; Keratinocytes; Microfilaments

Indexed keywords

ACTIN; CADHERIN; F ACTIN; G ACTIN;

ARTICLE; CELL ADHESION; CELL CONTACT; CELL JUNCTION; CELL SHAPE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; KERATINOCYTE; MICROFILAMENT; MUSCLE CONTRACTILITY; POLARIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STABILITY;

ACTINS; CELL ADHESION; CELL POLARITY; HUMANS; INTERCELLULAR JUNCTIONS; KERATINOCYTES;

EID: 30544433202     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02639     Document Type: Article

References (46)

1. Adams, C. L., Nelson, W. J. and Smith, S. J. (1996). Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion. J. Cell Biol. 135, 1899-1911.
2. Adams, C. L., Chen, Y.-T., Smith, S. J. and Nelson, W. J. (1998). Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein. J. Cell Biol. 142, 1105-1119.
3. Amato, P. A. and Taylor, D. L. (1986). Probing the mechanism of incorporation of fluorescently labeled actin into stress fibers. J. Cell Biol. 102, 1074-1084.
4. Betson, M., Lozano, E., Zhang, J. and Braga, V. M. M. (2002). Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor. J. Biol. Chem. 277, 36962-36969.
5. Bhowmick, N. A., Ghiassi, M., Bakin, A., Aakre, M., Lundquist, C. A., Engel, M. E., Arteaga, C. L. and Moses, H. L. (2001). Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA dependent mechanism. Mol. Biol. Cell 12, 27-36.
6. Braga, V. (2000). Cadherin adhesion regulation in keratinocytes. In Cell-Cell Interactions: a practical approach (ed. T. Fleming), pp. 1-36. Oxford: Oxford University Press.
7. Braga, V. M. M., Hodivala, K. J. and Watt, F. M. (1995). Calcium-induced changes in distribution and solubility of cadherins and their associated cytoplasmic proteins in human keratinocytes. Cell Adhes. Commun. 3, 201-215.
8. Braga, V. M. M., Najabagheri, N. and Watt, F.M. (1998). Calcium-induced intercellular adhesion of keratinocytes does not involve accumulation of β1 integrins at cell-cell contact sites and does not involve changes in the levels or phosphorylation of the catenins. Cell Adhes. Commun. 5, 137-139.
9. Braga, V. M. M., Machesky, L. M., Hall, A. and Hotchin, N. A. (1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J. Cell Biol. 137, 1421-1431.
10. Bubb, M. R., Senderowicz, A. M. J., Sausville, E. A., Duncan, K. L. K. and Korn, E. D. (1994). Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J. Biol. Chem. 269, 14869-14871.
11. Calautti, E., Grossi, M., Mammucari, C., Aoyama, Y., Pirro, M., Ono, Y., Li, J. and Dotto, G. P. (2002). Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell-cell adhesion. J. Cell Biol. 156, 137-148.
12. Chan, A. Y., Bailly, M., Zebba, N., Segall, J. E. and Condeelis, J. S. (2000). Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protusion. J. Cell Biol. 148, 531-542.
13. Clayton, L., Hall, A. and Johnson, M. H. (1999). A role for the Rho-like GTPases in the polarisation of mouse eight-cell blastomeres. Dev. Biol. 205, 322-331.
14. Collins, J. and Fleming, T. P. (1995). Epithelial differentiation in the mouse pre-implantation embryo: making adhesive cell contacts for the first time. Trends Biochem. Sci. 20, 307-312.
15. Cramer, L. P. (1999). Role of actin-filament disassembly in lamellipodium protrusion in motile cells revealed using the drug jasplakinotide. Curr. Biol. 9, 1095-1105.
16. Cramer, L., Briggs, L. and Dawe, H. (2002). Use of fluorescently labelled deoxyribonuclease I to spatially measure G-actin levels in migrating and non-migrating cells. Cell Mot. Cytoskeleton 51, 27-38.
17. Gloushankova, N. A., Krendel, M. F., Alieva, N. O., Bonder, E. M., Feder, H. H., Vasiliev, J. M. and Gelfand, I. M. (1998). Dynamics of contacts between lamellae of fibroblasts: essential role of the actin cytoskeleton. Proc. Natl. Acad. Sci. USA 95, 4362-4367.
18. Green, K. J., Geiger, B., Jones, J. C. R., Talian, J. C. and Goldman, R. D. (1987). The relationship between intermediate filaments and microfilaments before and during the formation of desmosomes and adherens-type junctions in mouse epidermal cells. J. Cell Biol. 104, 1389-1402.
19. Hirai, Y., Nose, A., Kobayashi, S. and Takeichi, M. (1989). Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. I. Lung epithelial morphogenesis. Development 105, 263-270.
20. Hodivala, K. J. and Watt, F. M. (1994). Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation. J. Cell Biol. 124, 589-600.
21. Krendel, M. F. and Bonder, E. M. (1999). Analysis of actin filament bundle dynamics during contact formation in live epithelial cells. Cell Motil. Cytoskeleton 43, 296-309.
22. Krendel, M., Gloushankova, N. A., Bonder, E. M., Feder, H. H., Vasiliev, J. M. and Gelfand, I. M. (1999). Myosin-dependent contractile activity of the actin cytoskeleton modulates the spatial organization of cell-cell contacts in cultured epitheliocytes. Proc. Natl. Acad. Sci. USA 96, 9666-9670.
23. Littlefield, R., Almenar-Queralt, A. and Fowler, V. M. (2001). Actin dynamics at pointed ends regulates thin filament length in striated muscle. Nat. Cell Biol. 3, 544-551.
24. Mandato, C. A. and Bement, W. M. (2001). Contraction and polymerization cooperate to assemble and close actomyosin rings around Xenopus oocyte wounds. J. Cell Biol. 154, 785-798.
25. McNeill, H., Ryan, T. A., Smith, S. J. and Nelson, J. W. (1993). Spatial and temporal dissection of immediate and early events following cadherin-mediated epithelial cell adhesion. J. Cell Biol. 120, 1217-1226.
26. Nelson, W. J. (2003). Adaptation of core mechanisms to generate cell polarity. Nature 422, 766-774.
27. Noren, N. K., Niessen, C. M., Gumbiner, B. M. and Burridge, K. (2001). Cadherin engagement regulates Rho family GTPases. J. Biol. Chem. 276, 33305-33308.
28. Owaribe, K., Kodama, R. and Eguchi, G. (1981). Demonstration of contractility of circumferential actin bundles and its morphogenetic significance in pigmented epithelium in vitro and in vivo. J. Cell Biol. 90, 507-514.
29. Philip, N. J. and Nachmias, V. T. (1985). Components of the cytoskeleton in the retinal pigmented epithelium of the chick. J. Cell Biol. 101, 358-362.
30. Pollard, T. D., Blanchoin, L. and Mullins, R. D. (2000). Molecular mechanisms controlling actin filament dynamics in non muscle cells. Annu. Rev. Biophys. Biomol. Struct. 29, 545-576.
31. Ridley, A. J., Schwartz, M. A., Burridge, K., Firtel, R. A., Ginsberg, M. H., Borisy, G., Parsons, J. T. and Horwitz, A. R. (2003). Cell migration: integrating signals from front to back. Science 302, 1704-1709.
32. Sahai, E. and Marshall, C. J. (2002). ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat. Cell Biol. 4, 408-415.
33. Sanger, J. W., Sanger, J. M. and Jockusch, B. M. (1983). Differences in the stress fibers between fibroblasts and epithelial cells. J. Cell Biol. 96, 961-969.
34. Sharpe, G. R., Fisher, C., Gillespie, J. I. and Greenwell, J. R. (1993). Growth and differentiation stimuli induce different and distinct increases in intracellular free calcium in human keratinocytes. Arch. Dermatol. Res. 284, 445-450.
35. Shimoyama, Y., Yoshida, T., Terada, M., Shimosato, Y., Abe, O. and Hirohashi, S. (1989). Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. J. Cell Biol. 109, 1787-1794.
36. Stoffler, H. E., Honnert, U., Bauer, C. A., Hofer, D., Schwarz, H., Muller, R. T., Dreckhahn, D. and Bahler, M. (1998). Targeting of the myosin-I to intercellular adherens type junctions induced by dominant active Cdc42 in Hela cells. J. Cell Sci. 111, 2779-2788.
37. Straight, A. F., Cheung, A., Limouze, J., Chen, I., Westwood, N. J., Sellers, J. R. and Mitchison, T. J. (2003). Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science 299, 1743-1747.
38. Theriot, J. A. and Mitchison, T. J. (1991). Actm microfilament dynamics in locomoting cells. Nature 352, 126-131.
39. Vaezi, A., Bauer, C., Vasioukhin, V. and Fuchs, E. (2002). Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epithelium. Dev. Cell 3, 367-381.
40. Vasioukhin, V., Bauer, C., Yin, M. and Fuchs, E. (2000). Directed actin polymerization is the driving force for epithelial cell-cell adhesion. Cell 100, 209-219.
41. Wissmann, A., Ingles, J. and Mains, P. E. (1999). The Caenorhabditis elegans mel-11 myosin phosphatase regulatory subunit affects tissue contraction in the somatic gonad and the embryonic epidermis and genetically interacts with the Rac signalling pathway. Dev. Biol. 209, 111-127.
42. Wozniak, M. A., Desai, R., Solski, P. A., Der, C. J. and Keely, P. J. (2003). ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. J. Cell Biol. 163, 583-595.
43. Yap, A. S., Brieher, W. M. and Gumbiner, B. M. (1997). Molecular and functional analysis of cadherin-based adherens junctions. Annu. Rev. Cell Dev. Biol. 13, 119-146.
44. Yonemura, S., Itoh, M., Nagafuchi, A. and Tsukita, S. (1995). Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J. Cell Sci. 108, 127-142.
45. Zamansky, G. B., Nguyen, U. and Chou, I.-N. (1991). An immunofluorescence study of the calcium-induced coordinated reorganization of microfilaments, keratin intermediate filaments, and microtubules in cultured human epidermal keratinocytes. J. Inv. Dermatol. 97, 985-994.
46. Zhong, C., Kinch, M. S. and Burridge, K. (1997). Rho-stimulated contractily contributes to the fibroblastic phenotype of Ras-transformed epithelial cells. Mol. Biol. Cell 8, 2329-2344.