메뉴 건너뛰기




Volumn 134, Issue 2, 2012, Pages 127-138

Targeting ASIC3 for pain, anxiety, and insulin resistance

Author keywords

APETx2; ASIC; Cardiac ischemia; Heart failure; Inflammation; Postoperative pain

Indexed keywords

ACID SENSING ION CHANNEL 3; AMILORIDE; ANALGESIC AGENT; BENZOTHIOPHENE DERIVATIVE; FREUND ADJUVANT; INSULIN; ION CHANNEL; PROTEIN KINASE B; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

EID: 84862803072     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2011.12.009     Document Type: Review
Times cited : (57)

References (123)
  • 1
    • 77249125805 scopus 로고    scopus 로고
    • The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation
    • K. Alawi, and J. Keeble The paradoxical role of the transient receptor potential vanilloid 1 receptor in inflammation Pharmacol Ther 125 2010 181 195
    • (2010) Pharmacol Ther , vol.125 , pp. 181-195
    • Alawi, K.1    Keeble, J.2
  • 2
    • 77958486556 scopus 로고    scopus 로고
    • Expression in Pichia pastoris and characterization of APETx2, a specific inhibitor of acid sensing ion channel 3
    • R. Anangi, C.C. Chen, Y.W. Lin, Y.R. Cheng, C.H. Cheng, and Y.C. Chen Expression in Pichia pastoris and characterization of APETx2, a specific inhibitor of acid sensing ion channel 3 Toxicon 56 2010 1388 1397
    • (2010) Toxicon , vol.56 , pp. 1388-1397
    • Anangi, R.1    Chen, C.C.2    Lin, Y.W.3    Cheng, Y.R.4    Cheng, C.H.5    Chen, Y.C.6
  • 3
    • 0034665984 scopus 로고    scopus 로고
    • Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+
    • K. Babinski, S. Catarsi, G. Biagini, and P. Seguela Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+ J Biol Chem 275 2000 28519 28525
    • (2000) J Biol Chem , vol.275 , pp. 28519-28525
    • Babinski, K.1    Catarsi, S.2    Biagini, G.3    Seguela, P.4
  • 4
    • 0032900533 scopus 로고    scopus 로고
    • Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties
    • DOI 10.1046/j.1471-4159.1999.0720051.x
    • K. Babinski, K.T. Le, and P. Seguela Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties J Neurochem 72 1999 51 57 (Pubitemid 29013876)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.1 , pp. 51-57
    • Babinski, K.1    Le, K.-T.2    Seguela, P.3
  • 5
    • 78449300659 scopus 로고    scopus 로고
    • Sensing muscle ischemia: Coincident detection of acid and ATP via interplay of two ion channels
    • W.T. Birdsong, L. Fierro, F.G. Williams, V. Spelta, L.A. Naves, and M. Knowles Sensing muscle ischemia: Coincident detection of acid and ATP via interplay of two ion channels Neuron 68 2010 739 749
    • (2010) Neuron , vol.68 , pp. 739-749
    • Birdsong, W.T.1    Fierro, L.2    Williams, F.G.3    Spelta, V.4    Naves, L.A.5    Knowles, M.6
  • 6
    • 77957003945 scopus 로고    scopus 로고
    • A role for acid-sensing ion channel 3, but not acid-sensing ion channel 2, in sensing dynamic mechanical stimuli
    • J. Borzan, C. Zhao, R.A. Meyer, and S.N. Raja A role for acid-sensing ion channel 3, but not acid-sensing ion channel 2, in sensing dynamic mechanical stimuli Anesthesiology 113 2010 647 654
    • (2010) Anesthesiology , vol.113 , pp. 647-654
    • Borzan, J.1    Zhao, C.2    Meyer, R.A.3    Raja, S.N.4
  • 7
    • 68149160090 scopus 로고    scopus 로고
    • Expression of acid-sensing ion channels in neurons of trapezoid body and lateral paragigantocellular nuclei in rat brain, and effects of intermittent hypoxia on their expression
    • X.L. Cao, Q. Chen, H. Zhou, Y.H. Tang, J.G. Xu, and Y. Zheng Expression of acid-sensing ion channels in neurons of trapezoid body and lateral paragigantocellular nuclei in rat brain, and effects of intermittent hypoxia on their expression Sichuan Da Xue Xue Bao Yi Xue Ban 40 2009 662 666
    • (2009) Sichuan da Xue Xue Bao Yi Xue Ban , vol.40 , pp. 662-666
    • Cao, X.L.1    Chen, Q.2    Zhou, H.3    Tang, Y.H.4    Xu, J.G.5    Zheng, Y.6
  • 9
    • 65249129029 scopus 로고    scopus 로고
    • Acid-sensing ion channels in neurones of the rat suprachiasmatic nucleus
    • C.H. Chen, Y.T. Hsu, C.C. Chen, and R.C. Huang Acid-sensing ion channels in neurones of the rat suprachiasmatic nucleus J Physiol 587 2009 1727 1737
    • (2009) J Physiol , vol.587 , pp. 1727-1737
    • Chen, C.H.1    Hsu, Y.T.2    Chen, C.C.3    Huang, R.C.4
  • 10
    • 68349111705 scopus 로고    scopus 로고
    • Expression and function of proton-sensing G-protein-coupled receptors in inflammatory pain
    • Y.J. Chen, C.W. Huang, C.S. Lin, W.H. Chang, and W.H. Sun Expression and function of proton-sensing G-protein-coupled receptors in inflammatory pain Mol Pain 5 2009 39
    • (2009) Mol Pain , vol.5 , pp. 39
    • Chen, Y.J.1    Huang, C.W.2    Lin, C.S.3    Chang, W.H.4    Sun, W.H.5
  • 12
    • 78651228626 scopus 로고    scopus 로고
    • Acid-sensing ion channel 3, but not capsaicin receptor TRPV1, plays a protective role in isoproterenol-induced myocardial ischemia in mice
    • C.F. Cheng, I.L. Chen, M.H. Cheng, W.S. Lian, C.C. Lin, and T.B. Kuo Acid-sensing ion channel 3, but not capsaicin receptor TRPV1, plays a protective role in isoproterenol-induced myocardial ischemia in mice Circ J 75 2011 174 178
    • (2011) Circ J , vol.75 , pp. 174-178
    • Cheng, C.F.1    Chen, I.L.2    Cheng, M.H.3    Lian, W.S.4    Lin, C.C.5    Kuo, T.B.6
  • 13
    • 77954078318 scopus 로고    scopus 로고
    • Probing localized neural mechanotransduction through surface-modified elastomeric matrices and electrophysiology
    • C.M. Cheng, Y.W. Lin, R.M. Bellin, R.L. Steward Jr., Y.R. Cheng, and P.R. LeDuc Probing localized neural mechanotransduction through surface-modified elastomeric matrices and electrophysiology Nat Protoc 5 2010 714 724
    • (2010) Nat Protoc , vol.5 , pp. 714-724
    • Cheng, C.M.1    Lin, Y.W.2    Bellin, R.M.3    Steward, Jr.R.L.4    Cheng, Y.R.5    Leduc, P.R.6
  • 14
    • 77951493120 scopus 로고    scopus 로고
    • Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells
    • W.S. Chung, J.M. Farley, A. Swenson, J.M. Barnard, G. Hamilton, and R. Chiposi Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells Am J Physiol Cell Physiol 298 2010 C1198 1208
    • (2010) Am J Physiol Cell Physiol , vol.298 , pp. 1198-1208
    • Chung, W.S.1    Farley, J.M.2    Swenson, A.3    Barnard, J.M.4    Hamilton, G.5    Chiposi, R.6
  • 15
    • 77951558509 scopus 로고    scopus 로고
    • Expression and response of acid-sensing ion channels (ASICs) in urinary bladder to cyclophosphamide (CYP)-induced cystitis
    • K. Corrow, B.M. Girard, and M.A. Vizzard Expression and response of acid-sensing ion channels (ASICs) in urinary bladder to cyclophosphamide (CYP)-induced cystitis Am J Physiol Renal Physiol 298 2010 F1130 F1139
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Corrow, K.1    Girard, B.M.2    Vizzard, M.A.3
  • 16
    • 17644411712 scopus 로고    scopus 로고
    • Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin
    • DOI 10.1523/JNEUROSCI.5239-04.2005
    • K. Dang, K. Bielefeldt, and G.F. Gebhart Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin J Neurosci 25 2005 3973 3984 (Pubitemid 40570430)
    • (2005) Journal of Neuroscience , vol.25 , Issue.15 , pp. 3973-3984
    • Dang, K.1    Bielefeldt, K.2    Gebhart, G.F.3
  • 18
    • 78049273246 scopus 로고    scopus 로고
    • Acid-sensing ion channels (ASICs): Pharmacology and implication in pain
    • E. Deval, X. Gasull, J. Noel, M. Salinas, A. Baron, and S. Diochot Acid-sensing ion channels (ASICs): Pharmacology and implication in pain Pharmacol Ther 128 2010 549 558
    • (2010) Pharmacol Ther , vol.128 , pp. 549-558
    • Deval, E.1    Gasull, X.2    Noel, J.3    Salinas, M.4    Baron, A.5    Diochot, S.6
  • 20
    • 56549096001 scopus 로고    scopus 로고
    • ASIC3, a sensor of acidic and primary inflammatory pain
    • E. Deval, J. Noel, N. Lay, A. Alloui, S. Diochot, and V. Friend ASIC3, a sensor of acidic and primary inflammatory pain EMBO J 27 2008 3047 3055
    • (2008) EMBO J , vol.27 , pp. 3047-3055
    • Deval, E.1    Noel, J.2    Lay, N.3    Alloui, A.4    Diochot, S.5    Friend, V.6
  • 21
    • 2342629343 scopus 로고    scopus 로고
    • A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons
    • DOI 10.1038/sj.emboj.7600177
    • S. Diochot, A. Baron, L.D. Rash, E. Deval, P. Escoubas, and S. Scarzello A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid-sensitive channel in sensory neurons EMBO J 23 2004 1516 1525 (Pubitemid 38579512)
    • (2004) EMBO Journal , vol.23 , Issue.7 , pp. 1516-1525
    • Diochot, S.1    Baron, A.2    Rash, L.D.3    Deval, E.4    Escoubas, P.5    Scarzello, S.6    Salinas, M.7    Lazdunski, M.8
  • 22
    • 70350705955 scopus 로고    scopus 로고
    • Do distinct populations of dorsal root ganglion neurons account for the sensory peptidergic innervation of the kidney?
    • T. Ditting, G. Tiegs, K. Rodionova, P.W. Reeh, W. Neuhuber, and W. Freisinger Do distinct populations of dorsal root ganglion neurons account for the sensory peptidergic innervation of the kidney? Am J Physiol Renal Physiol 297 2009 F1427 1434
    • (2009) Am J Physiol Renal Physiol , vol.297 , pp. 1427-1434
    • Ditting, T.1    Tiegs, G.2    Rodionova, K.3    Reeh, P.W.4    Neuhuber, W.5    Freisinger, W.6
  • 23
    • 2442699006 scopus 로고    scopus 로고
    • Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones
    • DOI 10.1113/jphysiol.2003.058693
    • L.J. Drew, D.K. Rohrer, M.P. Price, K.E. Blaver, D.A. Cockayne, and P. Cesare Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones J Physiol 556 2004 691 710 (Pubitemid 38660308)
    • (2004) Journal of Physiology , vol.556 , Issue.3 , pp. 691-710
    • Drew, L.J.1    Rohrer, D.K.2    Price, M.P.3    Blaver, K.E.4    Cockayne, D.A.5    Cesare, P.6    Wood, J.N.7
  • 26
    • 33645750797 scopus 로고    scopus 로고
    • ASIC3-immunoreactive neurons in the rat vagal and glossopharyngeal sensory ganglia
    • T. Fukuda, H. Ichikawa, R. Terayama, T. Yamaai, T. Kuboki, and T. Sugimoto ASIC3-immunoreactive neurons in the rat vagal and glossopharyngeal sensory ganglia Brain Res 1081 2006 150 155
    • (2006) Brain Res , vol.1081 , pp. 150-155
    • Fukuda, T.1    Ichikawa, H.2    Terayama, R.3    Yamaai, T.4    Kuboki, T.5    Sugimoto, T.6
  • 27
    • 13844299377 scopus 로고    scopus 로고
    • Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line
    • DOI 10.1113/jphysiol.2004.075069
    • D.P. Gitterman, J. Wilson, and A.D. Randall Functional properties and pharmacological inhibition of ASIC channels in the human SJ-RH30 skeletal muscle cell line J Physiol 562 2005 759 769 (Pubitemid 40246791)
    • (2005) Journal of Physiology , vol.562 , Issue.3 , pp. 759-769
    • Gitterman, D.P.1    Wilson, J.2    Randall, A.D.3
  • 28
    • 39049110691 scopus 로고    scopus 로고
    • ASIC proteins regulate smooth muscle cell migration
    • DOI 10.1016/j.mvr.2007.08.003, PII S0026286207001045
    • S.C. Grifoni, N.L. Jernigan, G. Hamilton, and H.A. Drummond ASIC proteins regulate smooth muscle cell migration Microvasc Res 75 2008 202 210 (Pubitemid 351240936)
    • (2008) Microvascular Research , vol.75 , Issue.2 , pp. 202-210
    • Grifoni, S.C.1    Jernigan, N.L.2    Hamilton, G.3    Drummond, H.A.4
  • 29
    • 33746584487 scopus 로고    scopus 로고
    • Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels
    • M. Groth, T. Helbig, V. Grau, W. Kummer, and R.V. Haberberger Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels Respir Res 7 2006 96
    • (2006) Respir Res , vol.7 , pp. 96
    • Groth, M.1    Helbig, T.2    Grau, V.3    Kummer, W.4    Haberberger, R.V.5
  • 30
    • 33745686066 scopus 로고    scopus 로고
    • Characterization of acid signaling in rat vagal pulmonary sensory neurons
    • Q. Gu, and L.Y. Lee Characterization of acid signaling in rat vagal pulmonary sensory neurons Am J Physiol Lung Cell Mol Physiol 291 2006 L58 65
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , pp. 58-65
    • Gu, Q.1    Lee, L.Y.2
  • 31
    • 65649118890 scopus 로고    scopus 로고
    • Silent myocardial ischemia
    • D.D. Gutterman Silent myocardial ischemia Circ J 73 2009 785 797
    • (2009) Circ J , vol.73 , pp. 785-797
    • Gutterman, D.D.1
  • 32
    • 69249228607 scopus 로고    scopus 로고
    • ASIC2a and ASIC3 heteromultimerize to form pH-sensitive channels in mouse cardiac dorsal root ganglia neurons
    • T. Hattori, J. Chen, A.M. Harding, M.P. Price, Y. Lu, and F.M. Abboud ASIC2a and ASIC3 heteromultimerize to form pH-sensitive channels in mouse cardiac dorsal root ganglia neurons Circ Res 105 2009 279 286
    • (2009) Circ Res , vol.105 , pp. 279-286
    • Hattori, T.1    Chen, J.2    Harding, A.M.3    Price, M.P.4    Lu, Y.5    Abboud, F.M.6
  • 34
    • 78650047802 scopus 로고    scopus 로고
    • Acid sensing by visceral afferent neurones
    • P. Holzer Acid sensing by visceral afferent neurones Acta Physiol (Oxf) 201 2011 63 75
    • (2011) Acta Physiol (Oxf) , vol.201 , pp. 63-75
    • Holzer, P.1
  • 35
    • 77951767398 scopus 로고    scopus 로고
    • Upregulations of P2X(3) and ASIC3 involve in hyperalgesia induced by cisplatin administration in rats
    • K. Hori, N. Ozaki, S. Suzuki, and Y. Sugiura Upregulations of P2X(3) and ASIC3 involve in hyperalgesia induced by cisplatin administration in rats Pain 149 2010 393 405
    • (2010) Pain , vol.149 , pp. 393-405
    • Hori, K.1    Ozaki, N.2    Suzuki, S.3    Sugiura, Y.4
  • 36
    • 34548662156 scopus 로고    scopus 로고
    • Nociceptors of dorsal root ganglion express proton-sensing G-protein-coupled receptors
    • C.W. Huang, J.N. Tzeng, Y.J. Chen, W.F. Tsai, C.C. Chen, and W.H. Sun Nociceptors of dorsal root ganglion express proton-sensing G-protein-coupled receptors Mol Cell Neurosci 36 2007 195 210
    • (2007) Mol Cell Neurosci , vol.36 , pp. 195-210
    • Huang, C.W.1    Tzeng, J.N.2    Chen, Y.J.3    Tsai, W.F.4    Chen, C.C.5    Sun, W.H.6
  • 37
    • 44149123309 scopus 로고    scopus 로고
    • Increase of insulin sensitivity and reversal of age-dependent glucose intolerance with inhibition of ASIC3
    • S.J. Huang, W.S. Yang, Y.W. Lin, H.C. Wang, and C.C. Chen Increase of insulin sensitivity and reversal of age-dependent glucose intolerance with inhibition of ASIC3 Biochem Biophys Res Commun 371 2008 729 734
    • (2008) Biochem Biophys Res Commun , vol.371 , pp. 729-734
    • Huang, S.J.1    Yang, W.S.2    Lin, Y.W.3    Wang, H.C.4    Chen, C.C.5
  • 38
    • 33846450301 scopus 로고    scopus 로고
    • Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia
    • DOI 10.1002/cne.21204
    • P.A. Hughes, S.M. Brierley, R.L. Young, and L.A. Blackshaw Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia J Comp Neurol 500 2007 863 875 (Pubitemid 46137723)
    • (2007) Journal of Comparative Neurology , vol.500 , Issue.5 , pp. 863-875
    • Hughes, P.A.1    Brierley, S.M.2    Young, R.L.3    Blackshaw, L.A.4
  • 39
    • 70350234542 scopus 로고    scopus 로고
    • Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue
    • T. Huque, B.J. Cowart, L. Dankulich-Nagrudny, E.A. Pribitkin, D.L. Bayley, and A.I. Spielman Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue PLoS One 4 2009 e7347
    • (2009) PLoS One , vol.4 , pp. 7347
    • Huque, T.1    Cowart, B.J.2    Dankulich-Nagrudny, L.3    Pribitkin, E.A.4    Bayley, D.L.5    Spielman, A.I.6
  • 40
    • 0030764973 scopus 로고    scopus 로고
    • Good pain, bad pain
    • DOI 10.1126/science.278.5336.239
    • J.M. Iadarola, and R.M. Caudle Good pain, bad pain Science 278 1997 239 240 (Pubitemid 27450861)
    • (1997) Science , vol.278 , Issue.5336 , pp. 239-240
    • Iadarola, M.J.1    Caudle, R.M.2
  • 41
    • 0037067795 scopus 로고    scopus 로고
    • The co-expression of ASIC3 with calcitonin gene-related peptide and parvalbumin in the rat trigeminal ganglion
    • DOI 10.1016/S0006-8993(02)02831-7, PII S0006899302028317
    • H. Ichikawa, and T. Sugimoto The co-expression of ASIC3 with calcitonin gene-related peptide and parvalbumin in the rat trigeminal ganglion Brain Res 943 2002 287 291 (Pubitemid 36120388)
    • (2002) Brain Research , vol.943 , Issue.2 , pp. 287-291
    • Ichikawa, H.1    Sugimoto, T.2
  • 42
    • 47049097585 scopus 로고    scopus 로고
    • Role of ASIC3 in the primary and secondary hyperalgesia produced by joint inflammation in mice
    • M. Ikeuchi, S.J. Kolker, L.A. Burnes, R.Y. Walder, and K.A. Sluka Role of ASIC3 in the primary and secondary hyperalgesia produced by joint inflammation in mice Pain 137 2008 662 669
    • (2008) Pain , vol.137 , pp. 662-669
    • Ikeuchi, M.1    Kolker, S.J.2    Burnes, L.A.3    Walder, R.Y.4    Sluka, K.A.5
  • 43
    • 0032540129 scopus 로고    scopus 로고
    • Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis
    • DOI 10.1006/bbrc.1998.8483
    • K. Ishibashi, and F. Marumo Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis Biochem Biophys Res Commun 245 1998 589 593 (Pubitemid 28418549)
    • (1998) Biochemical and Biophysical Research Communications , vol.245 , Issue.2 , pp. 589-593
    • Ishibashi, K.1    Marumo, F.2
  • 44
    • 0029983818 scopus 로고    scopus 로고
    • Pain due to tissue acidosis: A mechanism for inflammatory and ischemic myalgia?
    • DOI 10.1016/0304-3940(96)12576-3
    • U. Issberner, P.W. Reeh, and K.H. Steen Pain due to tissue acidosis: A mechanism for inflammatory and ischemic myalgia? Neurosci Lett 208 1996 191 194 (Pubitemid 26140154)
    • (1996) Neuroscience Letters , vol.208 , Issue.3 , pp. 191-194
    • Issberner, U.1    Reeh, P.W.2    Steen, K.H.3
  • 46
    • 66949177983 scopus 로고    scopus 로고
    • Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3
    • J.E. Jensen, T. Durek, P.F. Alewood, D.J. Adams, G.F. King, and L.D. Rash Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3 Toxicon 54 2009 56 61
    • (2009) Toxicon , vol.54 , pp. 56-61
    • Jensen, J.E.1    Durek, T.2    Alewood, P.F.3    Adams, D.J.4    King, G.F.5    Rash, L.D.6
  • 47
    • 33646204186 scopus 로고    scopus 로고
    • Proton sensitivity Ca2+ permeability and molecular basis of acid-sensing ion channels expressed in glabrous and hairy skin afferents
    • N. Jiang, K.K. Rau, R.D. Johnson, and B.Y. Cooper Proton sensitivity Ca2+ permeability and molecular basis of acid-sensing ion channels expressed in glabrous and hairy skin afferents J Neurophysiol 95 2006 2466 2478
    • (2006) J Neurophysiol , vol.95 , pp. 2466-2478
    • Jiang, N.1    Rau, K.K.2    Johnson, R.D.3    Cooper, B.Y.4
  • 48
    • 34447099726 scopus 로고    scopus 로고
    • Short-term sensitization of colon mechanoreceptors is associated with long-term hypersensitivity to colon distention in the mouse
    • DOI 10.1053/j.gastro.2007.04.042, PII S0016508507007949
    • R.C. Jones III, E. Otsuka, E. Wagstrom, C.S. Jensen, M.P. Price, and G.F. Gebhart Short-term sensitization of colon mechanoreceptors is associated with long-term hypersensitivity to colon distention in the mouse Gastroenterology 133 2007 184 194 (Pubitemid 47031128)
    • (2007) Gastroenterology , vol.133 , Issue.1 , pp. 184-194
    • Jones III, R.C.W.1    Otsuka, E.2    Wagstrom, E.3    Jensen, C.S.4    Price, M.P.5    Gebhart, G.F.6
  • 50
    • 28044453285 scopus 로고    scopus 로고
    • The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3
    • DOI 10.1523/JNEUROSCI.0703-05.2005
    • R.C. Jones III, L. Xu, and G.F. Gebhart The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3 J Neurosci 25 2005 10981 10989 (Pubitemid 41692628)
    • (2005) Journal of Neuroscience , vol.25 , Issue.47 , pp. 10981-10989
    • Jones III, R.C.W.1    Xu, L.2    Gebhart, G.F.3
  • 51
    • 36048960083 scopus 로고    scopus 로고
    • Anxiety and otovestibular disorders: Linking behavioral phenotypes in men and mice
    • DOI 10.1016/j.bbr.2007.07.032, PII S0166432807003762
    • A.V. Kalueff, K. Ishikawa, and A.J. Griffith Anxiety and otovestibular disorders: Linking behavioral phenotypes in men and mice Behav Brain Res 186 2008 1 11 (Pubitemid 350100891)
    • (2008) Behavioural Brain Research , vol.186 , Issue.1 , pp. 1-11
    • Kalueff, A.V.1    Ishikawa, K.2    Griffith, A.J.3
  • 52
    • 77957231525 scopus 로고    scopus 로고
    • Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
    • J. Karczewski, R.H. Spencer, V.M. Garsky, A. Liang, M.D. Leitl, and M.J. Cato Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2 Br J Pharmacol 161 2010 950 960
    • (2010) Br J Pharmacol , vol.161 , pp. 950-960
    • Karczewski, J.1    Spencer, R.H.2    Garsky, V.M.3    Liang, A.4    Leitl, M.D.5    Cato, M.J.6
  • 53
    • 56049104472 scopus 로고    scopus 로고
    • Genetic variation in the ASIC3 gene influences blood pressure levels in Taiwanese
    • Y.L. Ko, L.A. Hsu, S. Wu, M.S. Teng, H.H. Chang, and C.C. Chen Genetic variation in the ASIC3 gene influences blood pressure levels in Taiwanese J Hypertens 26 2008 2154 2160
    • (2008) J Hypertens , vol.26 , pp. 2154-2160
    • Ko, Y.L.1    Hsu, L.A.2    Wu, S.3    Teng, M.S.4    Chang, H.H.5    Chen, C.C.6
  • 54
    • 77951617386 scopus 로고    scopus 로고
    • Acid-sensing ion channel 3 expressed in type B synoviocytes and chondrocytes modulates hyaluronan expression and release
    • S.J. Kolker, R.Y. Walder, Y. Usachev, J. Hillman, D.L. Boyle, and G.S. Firestein Acid-sensing ion channel 3 expressed in type B synoviocytes and chondrocytes modulates hyaluronan expression and release Ann Rheum Dis 69 2010 903 909
    • (2010) Ann Rheum Dis , vol.69 , pp. 903-909
    • Kolker, S.J.1    Walder, R.Y.2    Usachev, Y.3    Hillman, J.4    Boyle, D.L.5    Firestein, G.S.6
  • 55
    • 0042926849 scopus 로고    scopus 로고
    • The ASICs: Signaling molecules? Modulators?
    • DOI 10.1016/S0166-2236(03)00210-8
    • O. Krishtal The ASICs: Signaling molecules? Modulators? Trends Neurosci 26 2003 477 483 (Pubitemid 37025785)
    • (2003) Trends in Neurosciences , vol.26 , Issue.9 , pp. 477-483
    • Krishtal, O.1
  • 58
    • 77952228354 scopus 로고    scopus 로고
    • Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567
    • S.D. Kuduk, C.N. Di Marco, V. Bodmer-Narkevitch, S.P. Cook, M.J. Cato, and A. Jovanovska Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567 ACS Chem Neurosci 1 2010 19 24
    • (2010) ACS Chem Neurosci , vol.1 , pp. 19-24
    • Kuduk, S.D.1    Di Marco, C.N.2    Bodmer-Narkevitch, V.3    Cook, S.P.4    Cato, M.J.5    Jovanovska, A.6
  • 60
    • 79953670885 scopus 로고    scopus 로고
    • Role of the acid-sensing ion channel 3 in blood volume control
    • C.H. Lee, S.H. Sun, S.H. Lin, and C.C. Chen Role of the acid-sensing ion channel 3 in blood volume control Circ J 75 2011 874 883
    • (2011) Circ J , vol.75 , pp. 874-883
    • Lee, C.H.1    Sun, S.H.2    Lin, S.H.3    Chen, C.C.4
  • 62
    • 78751675607 scopus 로고    scopus 로고
    • ASIC3 channels in multimodal sensory perception
    • W.G. Li, and T.L. Xu ASIC3 channels in multimodal sensory perception ACS Chem Neurosci 2 2011 26 37
    • (2011) ACS Chem Neurosci , vol.2 , pp. 26-37
    • Li, W.G.1    Xu, T.L.2
  • 63
    • 78649785634 scopus 로고    scopus 로고
    • ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain
    • W.G. Li, Y. Yu, Z.D. Zhang, H. Cao, and T.L. Xu ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain Mol Pain 6 2010 88
    • (2010) Mol Pain , vol.6 , pp. 88
    • Li, W.G.1    Yu, Y.2    Zhang, Z.D.3    Cao, H.4    Xu, T.L.5
  • 64
    • 70349443514 scopus 로고    scopus 로고
    • Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects
    • A.R. Light, A.T. White, R.W. Hughen, and K.C. Light Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects J Pain 10 2009 1099 1112
    • (2009) J Pain , vol.10 , pp. 1099-1112
    • Light, A.R.1    White, A.T.2    Hughen, R.W.3    Light, K.C.4
  • 65
    • 0842347348 scopus 로고    scopus 로고
    • The Discovery and Characterization of a Proton-Gated Sodium Current in Rat Retinal Ganglion Cells
    • DOI 10.1523/JNEUROSCI.3191-03.2004
    • S. Lilley, P. LeTissier, and J. Robbins The discovery and characterization of a proton-gated sodium current in rat retinal ganglion cells J Neurosci 24 2004 1013 1022 (Pubitemid 38177008)
    • (2004) Journal of Neuroscience , vol.24 , Issue.5 , pp. 1013-1022
    • Lilley, S.1    LeTissier, P.2    Robbins, J.3
  • 67
    • 59549092607 scopus 로고    scopus 로고
    • Understanding sensory nerve mechanotransduction through localized elastomeric matrix control
    • Y.W. Lin, C.M. Cheng, P.R. Leduc, and C.C. Chen Understanding sensory nerve mechanotransduction through localized elastomeric matrix control PLoS One 4 2009 e4293
    • (2009) PLoS One , vol.4 , pp. 4293
    • Lin, Y.W.1    Cheng, C.M.2    Leduc, P.R.3    Chen, C.C.4
  • 68
    • 37849010271 scopus 로고    scopus 로고
    • Identification and characterization of a subset of mouse sensory neurons that express acid-sensing ion channel 3
    • Y.W. Lin, M.Y. Min, C.C. Lin, W.N. Chen, W.L. Wu, and H.M. Yu Identification and characterization of a subset of mouse sensory neurons that express acid-sensing ion channel 3 Neuroscience 151 2008 544 557
    • (2008) Neuroscience , vol.151 , pp. 544-557
    • Lin, Y.W.1    Min, M.Y.2    Lin, C.C.3    Chen, W.N.4    Wu, W.L.5    Yu, H.M.6
  • 69
    • 34547101720 scopus 로고    scopus 로고
    • Acid-sensing ion channels in sensory perception
    • DOI 10.1074/jbc.R700011200
    • E. Lingueglia Acid-sensing ion channels in sensory perception J Biol Chem 282 2007 17325 17329 (Pubitemid 47100265)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.24 , pp. 17325-17329
    • Lingueglia, E.1
  • 70
    • 78249259702 scopus 로고    scopus 로고
    • Femoral artery occlusion increases expression of ASIC3 in dorsal root ganglion neurons
    • J. Liu, Z. Gao, and J. Li Femoral artery occlusion increases expression of ASIC3 in dorsal root ganglion neurons Am J Physiol Heart Circ Physiol 299 2010 H1357 1364
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. 1357-1364
    • Liu, J.1    Gao, Z.2    Li, J.3
  • 71
    • 82855167206 scopus 로고    scopus 로고
    • Chronic hypoxia-induced acid-sensitive ion channel expression in chemoafferent neurons contributes to chemoreceptor hypersensitivity
    • 10.1152/ajplung.00132.02011
    • X. Liu, L. He, B. Dinger, and S.J. Fidone Chronic hypoxia-induced acid-sensitive ion channel expression in chemoafferent neurons contributes to chemoreceptor hypersensitivity Am J Physiol Lung Cell Mol Physiol 2011 10.1152/ajplung.00132.02011
    • (2011) Am J Physiol Lung Cell Mol Physiol
    • Liu, X.1    He, L.2    Dinger, B.3    Fidone, S.J.4
  • 72
    • 0037115054 scopus 로고    scopus 로고
    • Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels
    • J. Mamet, A. Baron, M. Lazdunski, and N. Voilley Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels J Neurosci 22 2002 10662 10670 (Pubitemid 36005140)
    • (2002) Journal of Neuroscience , vol.22 , Issue.24 , pp. 10662-10670
    • Mamet, J.1    Baron, A.2    Lazdunski, M.3    Voilley, N.4
  • 73
    • 62249172184 scopus 로고    scopus 로고
    • Distribution of acid-sensing ion channel 3 in the rat hypothalamus
    • Q.Y. Meng, W. Wang, X.N. Chen, T.L. Xu, and J.N. Zhou Distribution of acid-sensing ion channel 3 in the rat hypothalamus Neuroscience 159 2009 1126 1134
    • (2009) Neuroscience , vol.159 , pp. 1126-1134
    • Meng, Q.Y.1    Wang, W.2    Chen, X.N.3    Xu, T.L.4    Zhou, J.N.5
  • 74
    • 41749104013 scopus 로고    scopus 로고
    • Muskelschmerz: Mechanismen und klinische bedeutung
    • DOI 10.3238/artzebl.2008.0214
    • S. Mense Muscle pain: Mechanisms and clinical significance Dtsch Arztebl Int 105 2008 214 219 (Pubitemid 351487273)
    • (2008) Deutsches Arzteblatt , vol.105 , Issue.12 , pp. 214-219
    • Mense, S.1
  • 75
    • 33748530286 scopus 로고    scopus 로고
    • Acid-sensing ionic channels in the rat vestibular endorgans and ganglia
    • DOI 10.1152/jn.00378.2006
    • F. Mercado, I.A. Lopez, D. Acuna, R. Vega, and E. Soto Acid-sensing ionic channels in the rat vestibular endorgans and ganglia J Neurophysiol 96 2006 1615 1624 (Pubitemid 44371548)
    • (2006) Journal of Neurophysiology , vol.96 , Issue.3 , pp. 1615-1624
    • Mercado, F.1    Lopez, I.A.2    Acuna, D.3    Vega, R.4    Soto, E.5
  • 77
    • 31644446447 scopus 로고    scopus 로고
    • ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons
    • D.C. Molliver, D.C. Immke, L. Fierro, M. Pare, F.L. Rice, and E.W. McCleskey ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons Mol Pain 1 2005 35
    • (2005) Mol Pain , vol.1 , pp. 35
    • Molliver, D.C.1    Immke, D.C.2    Fierro, L.3    Pare, M.4    Rice, F.L.5    McCleskey, E.W.6
  • 78
    • 45849146514 scopus 로고    scopus 로고
    • Effects of selective spinal nerve ligation on acetic acid-induced nociceptive responses and ASIC3 immunoreactivity in the rat dorsal root ganglion
    • M. Omori, M. Yokoyama, Y. Matsuoka, H. Kobayashi, S. Mizobuchi, and Y. Itano Effects of selective spinal nerve ligation on acetic acid-induced nociceptive responses and ASIC3 immunoreactivity in the rat dorsal root ganglion Brain Res 1219 2008 26 31
    • (2008) Brain Res , vol.1219 , pp. 26-31
    • Omori, M.1    Yokoyama, M.2    Matsuoka, Y.3    Kobayashi, H.4    Mizobuchi, S.5    Itano, Y.6
  • 79
    • 25444506199 scopus 로고    scopus 로고
    • Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function
    • DOI 10.1136/gut.2005.071084
    • A.J. Page, S.M. Brierley, C.M. Martin, M.P. Price, E. Symonds, and R. Butler Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function Gut 54 2005 1408 1415 (Pubitemid 41375197)
    • (2005) Gut , vol.54 , Issue.10 , pp. 1408-1415
    • Page, A.J.1    Brierley, S.M.2    Martin, C.M.3    Price, M.P.4    Symonds, E.5    Butler, R.6    Wemmie, J.A.7    Blackshaw, L.A.8
  • 80
    • 33748893261 scopus 로고    scopus 로고
    • Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
    • DOI 10.1113/jphysiol.2006.113035
    • O. Poirot, T. Berta, I. Decosterd, and S. Kellenberger Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury J Physiol 576 2006 215 234 (Pubitemid 44426232)
    • (2006) Journal of Physiology , vol.576 , Issue.1 , pp. 215-234
    • Poirot, O.1    Berta, T.2    Decosterd, I.3    Kellenberger, S.4
  • 82
    • 78650694288 scopus 로고    scopus 로고
    • Detection of acid-sensing ion channel 3 (ASIC3) in periodontal Ruffini endings of mouse incisors
    • F. Rahman, F. Harada, I. Saito, A. Suzuki, Y. Kawano, and K. Izumi Detection of acid-sensing ion channel 3 (ASIC3) in periodontal Ruffini endings of mouse incisors Neurosci Lett 488 2011 173 177
    • (2011) Neurosci Lett , vol.488 , pp. 173-177
    • Rahman, F.1    Harada, F.2    Saito, I.3    Suzuki, A.4    Kawano, Y.5    Izumi, K.6
  • 83
    • 2142707226 scopus 로고    scopus 로고
    • Acid-sensing ion channel-2 is not necessary for sour taste in mice
    • DOI 10.1523/JNEUROSCI.0653-04.2004
    • T.A. Richter, G.A. Dvoryanchikov, S.D. Roper, and N. Chaudhari Acid-sensing ion channel-2 is not necessary for sour taste in mice J Neurosci 24 2004 4088 4091 (Pubitemid 38544235)
    • (2004) Journal of Neuroscience , vol.24 , Issue.16 , pp. 4088-4091
    • Richter, T.A.1    Dvoryanchikov, G.A.2    Roper, S.D.3    Chaudhari, N.4
  • 86
    • 78751692683 scopus 로고    scopus 로고
    • Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters
    • M.L. Scattoni, L. Ricceri, and J.N. Crawley Unusual repertoire of vocalizations in adult BTBR T+tf/J mice during three types of social encounters Genes Brain Behav 10 2011 44 56
    • (2011) Genes Brain Behav , vol.10 , pp. 44-56
    • Scattoni, M.L.1    Ricceri, L.2    Crawley, J.N.3
  • 87
    • 1842784824 scopus 로고    scopus 로고
    • Increased expression of TRPV1 receptor in dorsal root ganglia by acid insult of the rat gastric mucosa
    • DOI 10.1111/j.1460-9568.2004.03290.x
    • R. Schicho, W. Florian, I. Liebmann, P. Holzer, and I.T. Lippe Increased expression of TRPV1 receptor in dorsal root ganglia by acid insult of the rat gastric mucosa Eur J Neurosci 19 2004 1811 1818 (Pubitemid 38482568)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.7 , pp. 1811-1818
    • Schicho, R.1    Florian, W.2    Liebmann, I.3    Holzer, P.4    Lippe, I.Th.5
  • 88
    • 0035157571 scopus 로고    scopus 로고
    • Unilateral intramuscular injections of acidic saline produce a bilateral, long-lasting hyperalgesia
    • DOI 10.1002/1097-4598(200101)24:1<37::AID-MUS4>3.0.CO;2-8
    • K.A. Sluka, A. Kalra, and S.A. Moore Unilateral intramuscular injections of acidic saline produce a bilateral, long-lasting hyperalgesia Muscle Nerve 24 2001 37 46 (Pubitemid 32038025)
    • (2001) Muscle and Nerve , vol.24 , Issue.1 , pp. 37-46
    • Sluka, K.A.1    Kalra, A.2    Moore, S.A.3
  • 89
    • 0344305593 scopus 로고    scopus 로고
    • Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1
    • DOI 10.1016/S0304-3959(03)00269-0
    • K.A. Sluka, M.P. Price, N.M. Breese, C.L. Stucky, J.A. Wemmie, and M.J. Welsh Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1 Pain 106 2003 229 239 (Pubitemid 37505871)
    • (2003) Pain , vol.106 , Issue.3 , pp. 229-239
    • Sluka, K.A.1    Price, M.P.2    Breese, N.M.3    Stucky, C.L.4    Wemmie, J.A.5    Welsh, M.J.6
  • 91
    • 0036721543 scopus 로고    scopus 로고
    • Chronic muscle pain induced by repeated acid injection is reversed by spinally administered μ- and δ-, but not κ-, opioid receptor agonists
    • DOI 10.1124/jpet.102.033167
    • K.A. Sluka, J.J. Rohlwing, R.A. Bussey, S.A. Eikenberry, and J.M. Wilken Chronic muscle pain induced by repeated acid Injection is reversed by spinally administered mu- and delta-, but not kappa-, opioid receptor agonists J Pharmacol Exp Ther 302 2002 1146 1150 (Pubitemid 34920237)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.302 , Issue.3 , pp. 1146-1150
    • Sluka, K.A.1    Rohlwing, J.J.2    Bussey, R.A.3    Eikenberry, S.A.4    Wilken, J.M.5
  • 93
    • 67349250447 scopus 로고    scopus 로고
    • Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test
    • A.A. Staniland, and S.B. McMahon Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test Eur J Pain 13 2009 554 563
    • (2009) Eur J Pain , vol.13 , pp. 554-563
    • Staniland, A.A.1    McMahon, S.B.2
  • 94
    • 0022572309 scopus 로고
    • Effects of visual and acoustic deprivation on agonistic behaviour of the albino mouse (M. musculus L.)
    • DOI 10.1016/0031-9384(86)90367-7
    • S. Strasser, and A.K. Dixon Effects of visual and acoustic deprivation on agonistic behaviour of the albino mouse (M. musculus L.) Physiol Behav 36 1986 773 778 (Pubitemid 16111762)
    • (1986) Physiology and Behavior , vol.36 , Issue.4 , pp. 773-778
    • Strasser, S.1    Dixon, A.K.2
  • 95
    • 0029847688 scopus 로고    scopus 로고
    • Sensitization of meningeal sensory neurons and the origin of headaches
    • DOI 10.1038/384560a0
    • A.M. Strassman, S.A. Raymond, and R. Burstein Sensitization of meningeal sensory neurons and the origin of headaches Nature 384 1996 560 564 (Pubitemid 26415932)
    • (1996) Nature , vol.384 , Issue.6609 , pp. 560-564
    • Strassman, A.M.1    Raymond, S.A.2    Burstein, R.3
  • 97
    • 34250643159 scopus 로고    scopus 로고
    • Mouse colon sensory neurons detect extracellular acidosis via TRPV1
    • T. Sugiura, K. Bielefeldt, and G.F. Gebhart Mouse colon sensory neurons detect extracellular acidosis via TRPV1 Am J Physiol Cell Physiol 292 2007 C1768 1774
    • (2007) Am J Physiol Cell Physiol , vol.292 , pp. 1768-1774
    • Sugiura, T.1    Bielefeldt, K.2    Gebhart, G.F.3
  • 98
    • 14944354848 scopus 로고    scopus 로고
    • Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach
    • DOI 10.1523/JNEUROSCI.2894-04.2005
    • T. Sugiura, K. Dang, K. Lamb, K. Bielefeldt, and G.F. Gebhart Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach J Neurosci 25 2005 2617 2627 (Pubitemid 40365173)
    • (2005) Journal of Neuroscience , vol.25 , Issue.10 , pp. 2617-2627
    • Sugiura, T.1    Dang, K.2    Lamb, K.3    Bielefeldt, K.4    Gebhart, G.F.5
  • 100
    • 36048946296 scopus 로고    scopus 로고
    • Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells
    • DOI 10.1161/CIRCRESAHA.107.154377
    • Z.Y. Tan, Y. Lu, C.A. Whiteis, C.J. Benson, M.W. Chapleau, and F.M. Abboud Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells Circ Res 101 2007 1009 1019 (Pubitemid 350084978)
    • (2007) Circulation Research , vol.101 , Issue.10 , pp. 1009-1019
    • Tan, Z.-Y.1    Lu, Y.2    Whiteis, C.A.3    Benson, C.J.4    Chapleau, M.W.5    Abboud, F.M.6
  • 101
    • 77649120606 scopus 로고    scopus 로고
    • Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR
    • Z.Y. Tan, Y. Lu, C.A. Whiteis, A.E. Simms, J.F. Paton, and M.W. Chapleau Chemoreceptor hypersensitivity, sympathetic excitation, and overexpression of ASIC and TASK channels before the onset of hypertension in SHR Circ Res 106 2010 536 545
    • (2010) Circ Res , vol.106 , pp. 536-545
    • Tan, Z.Y.1    Lu, Y.2    Whiteis, C.A.3    Simms, A.E.4    Paton, J.F.5    Chapleau, M.W.6
  • 103
    • 79953218352 scopus 로고    scopus 로고
    • Acid-sensing ion channels contribute to the effect of acidosis on the function of dendritic cells
    • J. Tong, W.N. Wu, X. Kong, P.F. Wu, L. Tian, and W. Du Acid-sensing ion channels contribute to the effect of acidosis on the function of dendritic cells J Immunol 186 2011 3686 3692
    • (2011) J Immunol , vol.186 , pp. 3686-3692
    • Tong, J.1    Wu, W.N.2    Kong, X.3    Wu, P.F.4    Tian, L.5    Du, W.6
  • 104
    • 38749098170 scopus 로고    scopus 로고
    • Expression of Acid-Sensing Ion Channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling
    • DOI 10.1359/jbmr.070805
    • Y. Uchiyama, C.C. Cheng, K.G. Danielson, J. Mochida, T.J. Albert, and I.M. Shapiro Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling J Bone Miner Res 22 2007 1996 2006 (Pubitemid 351229316)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.12 , pp. 1996-2006
    • Uchiyama, Y.1    Cheng, C.-C.2    Danielson, K.G.3    Mochida, J.4    Albert, T.J.5    Shapiro, I.M.6    Risbud, M.V.7
  • 105
    • 52949134780 scopus 로고    scopus 로고
    • SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc
    • Y. Uchiyama, A. Guttapalli, S. Gajghate, J. Mochida, I.M. Shapiro, and M.V. Risbud SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc J Bone Miner Res 23 2008 1619 1628
    • (2008) J Bone Miner Res , vol.23 , pp. 1619-1628
    • Uchiyama, Y.1    Guttapalli, A.2    Gajghate, S.3    Mochida, J.4    Shapiro, I.M.5    Risbud, M.V.6
  • 106
    • 0036802854 scopus 로고    scopus 로고
    • Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors
    • DOI 10.1172/JCI200215709
    • S. Ugawa, T. Ueda, Y. Ishida, M. Nishigaki, Y. Shibata, and S. Shimada Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors J Clin Invest 110 2002 1185 1190 (Pubitemid 35215899)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.8 , pp. 1185-1190
    • Ugawa, S.1    Ueda, T.2    Ishida, Y.3    Nishigaki, M.4    Shibata, Y.5    Shimada, S.6
  • 108
    • 0035887733 scopus 로고    scopus 로고
    • Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors
    • N. Voilley, J. de Weille, J. Mamet, and M. Lazdunski Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors J Neurosci 21 2001 8026 8033 (Pubitemid 32952759)
    • (2001) Journal of Neuroscience , vol.21 , Issue.20 , pp. 8026-8033
    • Voilley, N.1    De Weille, J.2    Mamet, J.3    Lazdunski, M.4
  • 109
    • 77649235024 scopus 로고    scopus 로고
    • ASIC1 and ASIC3 play different roles in the development of hyperalgesia after inflammatory muscle injury
    • R.Y. Walder, L.A. Rasmussen, J.D. Rainier, A.R. Light, J.A. Wemmie, and K.A. Sluka ASIC1 and ASIC3 play different roles in the development of hyperalgesia after inflammatory muscle injury J Pain 11 2010 210 218
    • (2010) J Pain , vol.11 , pp. 210-218
    • Walder, R.Y.1    Rasmussen, L.A.2    Rainier, J.D.3    Light, A.R.4    Wemmie, J.A.5    Sluka, K.A.6
  • 110
    • 0030946297 scopus 로고    scopus 로고
    • A proton-gated cation channel involved in acid-sensing
    • DOI 10.1038/386173a0
    • R. Waldmann, G. Champigny, F. Bassilana, C. Heurteaux, and M. Lazdunski A proton-gated cation channel involved in acid-sensing Nature 386 1997 173 177 (Pubitemid 27131444)
    • (1997) Nature , vol.386 , Issue.6621 , pp. 173-177
    • Waldmann, R.1    Champigny, G.2    Bassilana, F.3    Heurteaux, C.4    Lazdunski, M.5
  • 111
    • 0032103129 scopus 로고    scopus 로고
    • +-gated cation channels: Neuronal acid sensors in the NaC/DEG family of ion channels
    • DOI 10.1016/S0959-4388(98)80070-6
    • R. Waldmann, and M. Lazdunski H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels Curr Opin Neurobiol 8 1998 418 424 (Pubitemid 28288580)
    • (1998) Current Opinion in Neurobiology , vol.8 , Issue.3 , pp. 418-424
    • Waldmann, R.1    Lazdunski, M.2
  • 112
    • 33644875613 scopus 로고    scopus 로고
    • TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice
    • DOI 10.1161/CIRCULATIONAHA.105.556274, PII 0000301720051206000014
    • L. Wang, and D.H. Wang TRPV1 gene knockout impairs postischemic recovery in isolated perfused heart in mice Circulation 112 2005 3617 3623 (Pubitemid 43739540)
    • (2005) Circulation , vol.112 , Issue.23 , pp. 3617-3623
    • Wang, L.1    Wang, D.H.2
  • 113
    • 33748797928 scopus 로고    scopus 로고
    • Acid-sensing ion channels: Advances, questions and therapeutic opportunities
    • DOI 10.1016/j.tins.2006.06.014, PII S0166223606001706
    • J.A. Wemmie, M.P. Price, and M.J. Welsh Acid-sensing ion channels: Advances, questions and therapeutic opportunities Trends Neurosci 29 2006 578 586 (Pubitemid 44416458)
    • (2006) Trends in Neurosciences , vol.29 , Issue.10 , pp. 578-586
    • Wemmie, J.A.1    Price, M.P.2    Welsh, M.J.3
  • 114
    • 77953285662 scopus 로고    scopus 로고
    • Association between an ASIC3 gene variant and insulin resistance in Taiwanese
    • S. Wu, L.A. Hsu, H.H. Chou, M.S. Teng, H.H. Chang, and K.H. Yeh Association between an ASIC3 gene variant and insulin resistance in Taiwanese Clin Chim Acta 411 2010 1132 1136
    • (2010) Clin Chim Acta , vol.411 , pp. 1132-1136
    • Wu, S.1    Hsu, L.A.2    Chou, H.H.3    Teng, M.S.4    Chang, H.H.5    Yeh, K.H.6
  • 115
    • 77955144561 scopus 로고    scopus 로고
    • Mice lacking Asic3 show reduced anxiety-like behavior on the elevated plus maze and reduced aggression
    • W.L. Wu, Y.W. Lin, M.Y. Min, and C.C. Chen Mice lacking Asic3 show reduced anxiety-like behavior on the elevated plus maze and reduced aggression Genes Brain Behav 9 2010 603 614
    • (2010) Genes Brain Behav , vol.9 , pp. 603-614
    • Wu, W.L.1    Lin, Y.W.2    Min, M.Y.3    Chen, C.C.4
  • 116
    • 68349157476 scopus 로고    scopus 로고
    • Asic3(-/-) female mice with hearing deficit affects social development of pups
    • W.L. Wu, C.H. Wang, E.Y. Huang, and C.C. Chen Asic3(-/-) female mice with hearing deficit affects social development of pups PLoS One 4 2009 e6508
    • (2009) PLoS One , vol.4 , pp. 6508
    • Wu, W.L.1    Wang, C.H.2    Huang, E.Y.3    Chen, C.C.4
  • 117
    • 37849000674 scopus 로고    scopus 로고
    • Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis
    • T. Wultsch, E. Painsipp, A. Shahbazian, M. Mitrovic, M. Edelsbrunner, and M. Lazdunski Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis Pain 134 2008 245 253
    • (2008) Pain , vol.134 , pp. 245-253
    • Wultsch, T.1    Painsipp, E.2    Shahbazian, A.3    Mitrovic, M.4    Edelsbrunner, M.5    Lazdunski, M.6
  • 118
    • 33748362837 scopus 로고    scopus 로고
    • Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia
    • DOI 10.1161/01.RES.0000238388.79295.4c, PII 0000301220060901000010
    • J. Yagi, H.N. Wenk, L.A. Naves, and E.W. McCleskey Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia Circ Res 99 2006 501 509 (Pubitemid 44337822)
    • (2006) Circulation Research , vol.99 , Issue.5 , pp. 501-509
    • Yagi, J.1    Wenk, H.N.2    Naves, L.A.3    McCleskey, E.W.4
  • 119
    • 79953648285 scopus 로고    scopus 로고
    • Acid-sensing ion channels in blood volume regulation
    • M. Yamada Acid-sensing ion channels in blood volume regulation Circ J 75 2011 781 782
    • (2011) Circ J , vol.75 , pp. 781-782
    • Yamada, M.1
  • 120
    • 78650415308 scopus 로고    scopus 로고
    • Dural afferents express acid-sensing ion channels: A role for decreased meningeal pH in migraine headache
    • J. Yan, R.M. Edelmayer, X. Wei, M. De Felice, F. Porreca, and G. Dussor Dural afferents express acid-sensing ion channels: A role for decreased meningeal pH in migraine headache Pain 152 2011 106 113
    • (2011) Pain , vol.152 , pp. 106-113
    • Yan, J.1    Edelmayer, R.M.2    Wei, X.3    De Felice, M.4    Porreca, F.5    Dussor, G.6
  • 121
  • 123
    • 77957293978 scopus 로고    scopus 로고
    • A nonproton ligand sensor in the acid-sensing ion channel
    • Y. Yu, Z. Chen, W.G. Li, H. Cao, E.G. Feng, and F. Yu A nonproton ligand sensor in the acid-sensing ion channel Neuron 68 2010 61 72
    • (2010) Neuron , vol.68 , pp. 61-72
    • Yu, Y.1    Chen, Z.2    Li, W.G.3    Cao, H.4    Feng, E.G.5    Yu, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.